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2026 Journal Article The isolated thumb domain of acid‐sensing ion channels forms a minimal folding unit enabling ligand binding studiesMishra, Biswa P., Cristofori‐Armstrong, Ben, Budusan, Elena, Golder, Mimi, Butcher, Neville J., Liu, Junyu, Crawford, Theo, Chin, Yanni K.‐Y., Schmidt, Anneka Pereira, Jia, Xinying, Smallwood, Taylor B., Clark, Richard J., Wurm, Jan P., Rash, Lachlan D. and Mobli, Mehdi (2026). The isolated thumb domain of acid‐sensing ion channels forms a minimal folding unit enabling ligand binding studies. Angewandte Chemie, 138 (19) e23977, 1-12. doi: 10.1002/ange.202523977 |
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2026 Journal Article The nanobody Nb.C1 potentiates human acid-sensing ion channel 1a and 1bGolder, Mimi, Butcher, Neville J., Naughton, Jennifer D., Liu, Junyu, Crawford, Theo, Rash, Lachlan D., Mobli, Mehdi and Cristofori-Armstrong, Ben (2026). The nanobody Nb.C1 potentiates human acid-sensing ion channel 1a and 1b. European Journal of Pharmacology, 1022 178850, 178850-1022. doi: 10.1016/j.ejphar.2026.178850 |
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2026 Journal Article The Isolated Thumb Domain of Acid‐Sensing Ion Channels Forms a Minimal Folding Unit Enabling Ligand Binding StudiesMishra, Biswa P., Cristofori‐Armstrong, Ben, Budusan, Elena, Golder, Mimi, Butcher, Neville J., Liu, Junyu, Crawford, Theo, Chin, Yanni K.‐Y., Pereira Schmidt, Anneka, Jia, Xinying, Smallwood, Taylor B., Clark, Richard J., Wurm, Jan P., Rash, Lachlan D. and Mobli, Mehdi (2026). The Isolated Thumb Domain of Acid‐Sensing Ion Channels Forms a Minimal Folding Unit Enabling Ligand Binding Studies. Angewandte Chemie International Edition, 65 (19) e23977, 1-12. doi: 10.1002/anie.202523977 |
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2025 Journal Article Optimization of production and enzymatic efficiency for self‐cyclizing nanodisc proteinsNaughton, Jennifer D., Xie, Donghong, Zhu, Yifei, Cristofori‐Armstrong, Ben, Chin, Yanni K.‐Y., Jia, Xinying, Crawford, Theo and Mobli, Mehdi (2025). Optimization of production and enzymatic efficiency for self‐cyclizing nanodisc proteins. Protein Science, 35 (1) e70429, e70429. doi: 10.1002/pro.70429 |
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2025 Journal Article Refining the NaV1.7 pharmacophore of a class of venom-derived peptide inhibitors via a combination of in silico screening and rational engineeringSharma, Gagan, Deuis, Jennifer R., Jia, Xinying, Crawford, Theo, Rahnama, Sassan, Undheim, Eivind A. B., Vetter, Irina, Chin, Yanni K.Y. and Mobli, Mehdi (2025). Refining the NaV1.7 pharmacophore of a class of venom-derived peptide inhibitors via a combination of in silico screening and rational engineering. Febs Letters, 599 (12), 1717-1732. doi: 10.1002/1873-3468.70036 |
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2024 Journal Article Structural basis of the bivalency of the TRPV1 agonist DkTxRamanujam, Venkatraman, Crawford, Theo, Cristofori‐Armstrong, Ben, Deuis, Jennifer R., Jia, Xinying, Maxwell, Michael J., Jami, Sina, Ma, Linlin, Vetter, Irina and Mobli, Mehdi (2024). Structural basis of the bivalency of the TRPV1 agonist DkTx. Angewandte Chemie, 136 (3), 1-8. doi: 10.1002/ange.202314621 |
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2024 Journal Article Structural basis of the bivalency of the TRPV1 agonist DkTxRamanujam, Venkatraman, Crawford, Theo, Cristofori-Armstrong, Ben, Deuis, Jennifer, Jia, Xinying, Maxwell, Michael, Jami, Sina, Ma, Linlin, Vetter, Irina and Mobli, Mehdi (2024). Structural basis of the bivalency of the TRPV1 agonist DkTx. Angewandte Chemie International Edition, 63 (3) e202314621, 1-8. doi: 10.1002/anie.202314621 |
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2023 Journal Article Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisationJia, Xinying, Chin, Yanni K.-Y., Zhang, Alan H., Crawford, Theo, Zhu, Yifei, Fletcher, Nicholas L., Zhou, Zihan, Hamilton, Brett R., Stroet, Martin, Thurecht, Kristofer J. and Mobli, Mehdi (2023). Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation. Communications Chemistry, 6 (1) 48, 1-10. doi: 10.1038/s42004-023-00841-5 |
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2023 Journal Article Structural conformation and activity of spider-derived inhibitory cystine knot peptide Pn3a are modulated by pHTran, Poanna, Crawford, Theo, Ragnarsson, Lotten, Deuis, Jennifer R., Mobli, Mehdi, Sharpe, Simon J., Schroeder, Christina I. and Vetter, Irina (2023). Structural conformation and activity of spider-derived inhibitory cystine knot peptide Pn3a are modulated by pH. ACS Omega, 8 (29), 26276-26286. doi: 10.1021/acsomega.3c02664 |
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2023 Journal Article Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 functionJami, Sina, Deuis, Jennifer R., Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L., Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R., Ju, Robert J., Robinson, Samuel D., Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L., Tran, Hue N. T., Chin, Yanni K.-Y., Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M., Andersson, David A., Rash, Lachlan D., Wood, John N. ... Vetter, Irina (2023). Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function. Nature Communications, 14 (1) 2442. doi: 10.1038/s41467-023-37963-2 |
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2023 Journal Article A bivalent remipede toxin promotes calcium release via ryanodine receptor activationMaxwell, Michael J., Thekkedam, Chris, Lamboley, Cedric, Chin, Yanni K.-Y., Crawford, Theo, Smith, Jennifer J., Liu, Junyu, Jia, Xinying, Vetter, Irina, Laver, Derek R., Launikonis, Bradley S., Dulhunty, Angela, Undheim, Eivind A. B. and Mobli, Mehdi (2023). A bivalent remipede toxin promotes calcium release via ryanodine receptor activation. Nature Communications, 14 (1) 1036, 1-13. doi: 10.1038/s41467-023-36579-w |
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2023 Journal Article ScrepYard: an online resource for disulfide-stabilised tandem repeat peptidesLiu, Junyu, Maxwell, Michael, Cuddihy, Thom, Crawford, Theo, Bassetti, Madeline, Hyde, Cameron, Peigneur, Steve, Tytgat, Jan, Undheim, Eivind A.B. and Mobli, Mehdi (2023). ScrepYard: an online resource for disulfide-stabilised tandem repeat peptides. Protein Science, 32 (2) e4566, 1-12. doi: 10.1002/pro.4566 |
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2022 Journal Article Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivoAnane-Adjei, Akosua B., Fletcher, Nicholas L., Cavanagh, Robert J., Houston, Zachary H., Crawford, Theodore, Pearce, Amanda K., Taresco, Vincenzo, Ritchie, Alison A., Clarke, Phillip, Grabowska, Anna M., Gellert, Paul R., Ashford, Marianne B., Kellam, Barrie, Thurecht, Kristofer J. and Alexander, Cameron (2022). Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo. Biomaterials Science, 10 (9), 2328-2344. doi: 10.1039/d1bm01548f |
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2021 Other Outputs A fusion proteinMobli, Mohammadmehdi, Jia, Xinying, Chin, Yanni Ka-Yan, Zhang, Alan Harry and Crawford, Theo Gene (2021). A fusion protein. WO/2021/248185. |
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2019 Journal Article A new vector coupling ligation-independent cloning with sortase a fusion for efficient cloning and one-step purification of tag-free recombinant proteinsJia, Xinying, Crawford, Theo, Zhang, Alan H. and Mobli, Mehdi (2019). A new vector coupling ligation-independent cloning with sortase a fusion for efficient cloning and one-step purification of tag-free recombinant proteins. Protein Expression and Purification, 161, 1-7. doi: 10.1016/j.pep.2019.04.004 |
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2019 Other Outputs B. anthracis protective antigen: a molecular imaging agent targeting squamous cell carcinomaCrawford, Theo (2019). B. anthracis protective antigen: a molecular imaging agent targeting squamous cell carcinoma. PhD Thesis, Queensland Brain Institute, The University of Queensland. doi: 10.14264/uql.2019.579 |
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2019 Journal Article Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell CarcinomaCrawford, Theo, Fletcher, Nicholas, Veitch, Margaret, Gonzalez Cruz, Jazmina L., Pett, Nicola, Brereton, Ian, Wells, James W., Mobli, Mehdi and Tesiram, Yasvir (2019). Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma. Frontiers in Medicine, 6 (FEB) 22, 22. doi: 10.3389/fmed.2019.00022 |
