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2016 Other Outputs Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseasesBhandari, Ashok, Bourne, Gregory, Cheng, Xiaoli, Frederick, Brian Troy, Zhang, Jie, Patel, Dinesh V. and Liu, David (2016). Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases. WO2017011820. |
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2016 Other Outputs Hepcidin and mini-hepcidin analogues and uses therofBourne, Gregory Thomas, Smythe, Mark Leslie, Frederick, Brian Troy and Vink, Simone (2016). Hepcidin and mini-hepcidin analogues and uses therof. WO2015200916A2. |
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2016 Conference Publication Discovery of novel and potent orally stable peptide antagonists of the human IL-23 receptor and their pre-clinical POC in rat colitis modelsBhandari, Ashok, Cheng, Xiaoli, Bourne, Greg T., Frederick, Brian, Zhang, Jenny, McMahon, Jaimee, Celino, Herodion, Zemede, Genet, Vinh Tran,, Tovera, James, Dogra, Mridula, Bai, Lu, Zhao, Li, Lister, Harriet, Shah, Shairaz, Annamalai, Thamil, Mattheakis, Larry, Patel, Dinesh and Liu, David (2016). Discovery of novel and potent orally stable peptide antagonists of the human IL-23 receptor and their pre-clinical POC in rat colitis models. Digestive Disease Week (DDW), San Diego, CA, United States, 20-24 May 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/s0016-5085(16)30739-9 |
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2016 Conference Publication Novel hepcidin mimeticsBourne, Greg, Smythe, Mark, Frederick, Brian, Scott, Sonya, Vink, Simone, Fog, Jacob Ulrik, Tofteng-Shelton, Pernille and Madala, Praveen (2016). Novel hepcidin mimetics. 6th Meeting of the International BioIron Society, Hangzhou, China, 6-10 September 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/ajh.24277 |
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2015 Journal Article Discovery and characterization of a potent interleukin-6 binding peptide with neutralizing activity in vivoRanganath, Sheila, Bhandari, Ashok, Avitahl-Curtis, Nicole, McMahon, Jaimee, Wachtel, Derek, Zhang, Jenny, Leitheiser, Christopher, Bernier, Sylvie G., Liu, Guang, Tran, Tran T., Celino, Herodion, Tobin, Jenny, Jung, Joon, Zhao, Hong, Glen, Katie E., Graul, Chris, Griffin, Aliesha, Schairer, Wayne C., Higgins, Carolyn, Reza, Tammi L., Mowe, Eva, Rivers, Sam, Scott, Sonya, Monreal, Alex, Shea, Courtney, Bourne, Greg, Coons, Casey, Smith, Adaline, Tang, Kim ... Carlson, Kenneth E. (2015). Discovery and characterization of a potent interleukin-6 binding peptide with neutralizing activity in vivo. PLoS One, 10 (11) e0141330, 1-19. doi: 10.1371/journal.pone.0141330 |
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2015 Other Outputs Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseasesPatel, Dinesh V., Liu, David, Bourne, Gregory, Bhandari, Ashok, Cheng, Xiaoli and Frederick, Brian Troy (2015). Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases. WO2016011208A1. |
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2015 Other Outputs Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseasesBourne, Gregory Thomas, Bhandari, Ashok, Cheng, Xiaoli, Frederick, Brian Troy, Zhang, Jie and Patel, Dinesh V. (2015). Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases. US9624268B2. |
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2014 Other Outputs Hepcidin analogues and uses therofSmythe, Mark Leslie, Bourne, Gregory Thomas, Vink, Simone, Frederick, Brian T., Madala, Praveen, Tofteng Shelton, Anne Pernille and Fog, Jacob Ulrik (2014). Hepcidin analogues and uses therof. WO2014145561A2. |
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2013 Conference Publication Replacement of peptide amide bond by amide nitroxide to enhance precision of distance distributions by DEER EPRMarshall, Garland R., Kulis, Christina, Bourne, Gregory T., Hindson, Christopher M., Hanson, Graeme R. and Smythe, Mark L. (2013). Replacement of peptide amide bond by amide nitroxide to enhance precision of distance distributions by DEER EPR. 23rd American Peptide Symposium, Waikoloa, HI, United States, 22-27 June 2013. Hoboken, NJ, United States: John Wiley & Sons. |
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2013 Journal Article Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel(1)Pettit, George R., Tang, Yuping, Zhang, Qingwen, Bourne, Gregory T., Arm, Christoph A., Leet, John E., Knight, John C., Pettit, Robin K., Chapuis, Jean-Charles, Doubek, Dennis L., Ward, Franklin J., Weber, Christine and Hooper, John N. A. (2013). Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel(1). Journal of Natural Products, 76 (3), 420-424. doi: 10.1021/np300828y |
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2010 Journal Article Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthasesChrist, Angelika N., Labzin, Larisa, Bourne, Gregory T., Fukunishi, Hirotada, Weber, Jane E., Sweet, Matthew J., Smythe, Mark L. and Flanagan, Jack U. (2010). Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthases. Journal of Medicinal Chemistry, 53 (15), 5536-5548. doi: 10.1021/jm100194a |
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2010 Journal Article Synthesis of the phenylpyridal scaffold as a helical peptide mimeticBourne, Gregory T., Kuster, Daniel J. and Marshall, Garland R. (2010). Synthesis of the phenylpyridal scaffold as a helical peptide mimetic. Chemistry: A European Journal, 16 (28), 8439-8445. doi: 10.1002/chem.201000315 |
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2010 Conference Publication Design, synthesis and evaluation of inhibitors targeting the SHP-1 catalytic domainKulis, C., Bourne, G., Kellie, S. and Smythe, M. (2010). Design, synthesis and evaluation of inhibitors targeting the SHP-1 catalytic domain. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.1303 |
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2008 Journal Article Library of biphenyl privileged substructures using a safety-catch linker approachSeverinsen, Rune, Bourne, Gregory T., Tran, Tran T., Ankersen, Michael, Begtrup, Mikael and Smythe, Mark L. (2008). Library of biphenyl privileged substructures using a safety-catch linker approach. Journal of Combinatorial Chemistry, 10 (4), 557-566. doi: 10.1021/cc800006g |
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2008 Journal Article Cyclic tetrapeptides via the ring contraction strategy: Chemical techniques useful for their identificationHorton, D. A., Bourne, G. T., Coughlan, J., Kaiser, S. M., Jacobs, C. M., Jones, A., Ruhmann, A., Turner, J. Y. and Smythe, M. L. (2008). Cyclic tetrapeptides via the ring contraction strategy: Chemical techniques useful for their identification. Organic & Biomolecular Chemistry, 6 (8), 1386-1395. doi: 10.1039/b800464a |
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2007 Journal Article Conformational manifold of α-aminoisobutyric acid (Aib) containing alanine-Based tripeptides in aqueous solution explored by vibrational spectroscopy, electronic circular dichroism spectroscopy, and molecular dynamics simulationsSchweitzer-Stenner, Reinhard, Gonzales, Widalys, Bourne, Gregory T., Feng, Jianwen A. and Marshall, Garland R. (2007). Conformational manifold of α-aminoisobutyric acid (Aib) containing alanine-Based tripeptides in aqueous solution explored by vibrational spectroscopy, electronic circular dichroism spectroscopy, and molecular dynamics simulations. Journal of the American Chemical Society, 129 (43), 13095-13109. doi: 10.1021/ja0738430 |
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2006 Journal Article A gradient descent algorithm for minimizing amino acid coupling reactions when synthesizing cyclic-peptide librariesDarwen, PJ, Tran, TT, Bourne, GT, Nielson, JL and Smythe, ML (2006). A gradient descent algorithm for minimizing amino acid coupling reactions when synthesizing cyclic-peptide libraries. Combinatorial Chemistry & High Throughput Screening, 9 (7), 559-563. doi: 10.2174/138620706777935333 |
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2005 Journal Article A convenient method for synthesis of cyclic peptide librariesBourne, Gregory T, Nielson, Jonathon L, Coughlan, Justin F, Darwen, Paul, Campitelli, Marc R, Horton, Douglas A, Rhümann, Andreas, Love, Stephen G, Tran, Tran T and Smythe, Mark L (2005). A convenient method for synthesis of cyclic peptide libraries. Methods in molecular biology (Clifton, N.J.), 298, 151-165. doi: 10.1385/1-59259-877-3:151 |
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2005 Journal Article A safety catch linker for Fmoc-based assembly of constrained cyclic peptidesRavn, J, Bourne, GT and Smythe, ML (2005). A safety catch linker for Fmoc-based assembly of constrained cyclic peptides. Journal of Peptide Science, 11 (9), 572-578. doi: 10.1002/psc.651 |
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2005 Journal Article Topological side-chain classification of beta-turns: Ideal motifs for peptidomimetic developmentTran, TT, McKie, J, Meutermans, WDF, Bourne, GT, Andrews, PR and Smythe, ML (2005). Topological side-chain classification of beta-turns: Ideal motifs for peptidomimetic development. Journal of Computer-aided Molecular Design, 19 (8), 551-566. doi: 10.1007/s10822-005-9006-2 |
