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2024 Conference Publication Intervention with an NLRP3 inhibitor does not prevent cardiovascular and cystic burden in a pre-clinical model of polycystic kidney diseaseMajor, Emily, Gasperoni, Jemma, Barton, Sean, Phillips, Jacqueline, Robertson, Avril, Dinh, Quynh, Drummond, Grant and Huuskes, Brooke (2024). Intervention with an NLRP3 inhibitor does not prevent cardiovascular and cystic burden in a pre-clinical model of polycystic kidney disease. 59th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Adelaide, SA, Australia, 31 August–4 September 2024. Richmond, VIC, Australia: John Wiley & Sons. |
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2024 Conference Publication Neuroinflammation drives acute lymphoblastic leukemia therapy-induced neuropathyStarobova, Hana, McCalmont, Hannah, Shatunova, Svetlana, Tay, Nicolette, Winkler, Ingrid, Robertson, Avril, Lock, Richard and Vetter, Irina (2024). Neuroinflammation drives acute lymphoblastic leukemia therapy-induced neuropathy. 2024 PNS Annual Meeting, Montreal, Canada, 22 - 25 June 2024. Hoboken, NJ, United States: Wiley-Blackwell Publishing. |
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2023 Conference Publication Targeting single inflammation marker IL-1Β does not alter development of advanced atherosclerotic plaques in high-fat diet-fed ApoE knockout miceWallert, M., Maluenda, A., Chen, Y. -C., Searle, A., Ziegler, M., Ying, Y. -L., Wu, E., Hosseini, H., Noonan, J., Zaldivia, M., Bormel, L., Eddy, E., Bongcaron, V., Witt, R., Wang, X., Lorkowski, S., Bobik, A., Robertson, A., Drummond, G., Mcfadyen, J. and Peter, K. (2023). Targeting single inflammation marker IL-1Β does not alter development of advanced atherosclerotic plaques in high-fat diet-fed ApoE knockout mice. 91st Annual Meeting of the European-Atherosclerosis-Society (EAS), Mannheim, Germany, 21-24 May 2023. E Park, Shannon, Ireland: Elsevier Ireland. |
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2022 Conference Publication Interaction between type 2 cytokine and inflammasome responses in the pathogenesis of obesity-associated asthmaPinkerton, J., Kim, R., Brown, A., Rae, B., Donovan, C., Mayall, J., Ali, M. K., Scott, H., Berthon, B., Baines, K., Starkey, M., Kermani, N., Guo, Y., Robertson, A., O'Neill, L., Adcock, , Cooper, M., Gibson, P., Wood, L., Hansbro, P. and Horvat, J. (2022). Interaction between type 2 cytokine and inflammasome responses in the pathogenesis of obesity-associated asthma. International Congress of the European-Respiratory-Society (ERS), Barcelona Spain, Sep 04-06, 2022. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2022.871 |
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2020 Conference Publication Targeting the NLRP3 inflammasome as a novel approach to treat pulmonary hypertensionScott, T. E., Ung, V., Baliga, R. S., Robertson, A. A. B., Nold-Petry, C. A., Nold, M. F., Drummond, G. R., Hobbs, A. J. and Kemp-Harper, B. K. (2020). Targeting the NLRP3 inflammasome as a novel approach to treat pulmonary hypertension. International Conference of the American Thoracic Society, Electr Network, 2020. New York, NY, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3830 |
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2019 Conference Publication IL-5/IL-13 drive NLRP3 inflammasome-mediated, steroid-resistant AHR in a model of obesity-associated asthmaPinkerton, James, Kim, Richard, Brown, Alexandra, Rae, Brittany, Mayall, Jemma, Ali, Md. Khadem, Starkey, Malcolm, Robertson, Avril, Wood, Lisa, Cooper, Matthew, O'Neill, Luke, Hansbro, Philip and Horvat, Jay (2019). IL-5/IL-13 drive NLRP3 inflammasome-mediated, steroid-resistant AHR in a model of obesity-associated asthma. European Respiratory Society (ERS) International Congress, Madrid, Spain, 28 September-2 October 2019. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2019.pa3345 |
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2019 Conference Publication Inhibition of NLRP3 does not protect against photo-oxidative damage-induced retinal degenerationWooff, Yvette, Fernando, Nilisha, Wong, Josephine, Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua Aaron, Doyle, Sarah, Robertson, Avril, Man, Si Ming and Natoli, Riccardo Carlo (2019). Inhibition of NLRP3 does not protect against photo-oxidative damage-induced retinal degeneration. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Vancouver, Canada, 28 April - 2 May 2019. Rockville, MD, United States: Association for Research in Vision and Ophthalmology. |
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2017 Conference Publication High Fat Diet-Induced Obesity Promotes Steroid-Resistant Asthma Through An Nlrp3 Inflammasome-Dependent MechanismPinkerton, James, Kim, Richard, Mayall, Jemma, Ali, Md. Khadem, Starkey, Malcolm, Robertson, Avril, O'Neill, Luke, Cooper, Matthew, Hansbro, Philip and Horvat, Jay (2017). High Fat Diet-Induced Obesity Promotes Steroid-Resistant Asthma Through An Nlrp3 Inflammasome-Dependent Mechanism. HOBOKEN: WILEY. |
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2017 Conference Publication Understanding IMPDH and ADSS in Cryptococcus neoformans andtheir inhibitors designKummari, Lalith Kumar, Furlong, Emily, Luo, Zhenyao, Blundell, Ross, Kappler, Ulrike, Butler, Mark, Robertson, Avril, Cooper, Matthew, Fraser, James and Kobe, Bostjan (2017). Understanding IMPDH and ADSS in Cryptococcus neoformans andtheir inhibitors design. CHESTER: INT UNION CRYSTALLOGRAPHY. doi: 10.1107/S205327331709324X |
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2016 Conference Publication A Small-molecule Inhibitor of NLRP3 Inflammasome Activity, MCC950, Reduces Blood Pressure and Restores Renal Function in Hypertensive MiceFerens, Dorota M., Krishnan, Shalini M., Kett, Michelle M., Ling, Yeong H., Mirabito, Katrina M., Robertson, Avril A., Cooper, Matthew A., Vinh, Antony, Chan, Christopher T., Mansell, Ashley, Sobey, Christopher G. and Drummond, Grant R. (2016). A Small-molecule Inhibitor of NLRP3 Inflammasome Activity, MCC950, Reduces Blood Pressure and Restores Renal Function in Hypertensive Mice. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. |
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2016 Conference Publication NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive steroid-resistant asthmaHorvat, Jay, Kim, Richard, Pinkerton, James, Essilfie, Ama-Tawiah, Robertson, Avril, Baines, Katherine, Mayall, Jemma, Starkey, Malcolm, Wark, Peter, Gibson, Peter, O'Neill, Luke, Cooper, Matthew and Hansbro, Philip (2016). NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive steroid-resistant asthma. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2016.PA564 |
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2016 Conference Publication Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survivalTate, M., Pinar, A., Dowling, J., McAuley, J., Robertson, A., Cooper, M. and Mansell, A. (2016). Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survival. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive severe, steroid-resistant asthmaKim, R., Pinkerton, J., Essilfie, A. -T, Robertson, A., Baines, K., Mayall, J., Starkey, M., Wark, P., Gibson, P., O'neill, L., Cooper, M., Horvat, J. and Hansbro, P. (2016). NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive severe, steroid-resistant asthma. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Autocrine NLRP3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+T cellsArbore, G., West, E., Robertson, A., Klos, A., Rheinheimer, C., Dutow, P., Woodruff, T., O'Neill, L., Coll, R., Sher, A., Leonard, W., Koehl, J., Monk, P., Cooper, M., Arno, M., Afzali, B., Lachmann, H., Cope, A., Mayer-Barber, K. and Kemper, C. (2016). Autocrine NLRP3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+T cells. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infectionTate, M., Ong, J., Dowling, J., Robertson, A., Cooper, M. and Mansell, A. (2016). Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infection. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Human monocytes engage an alternative inflammasome pathwayGaidt, M., Ebert, T., Chauhan, D., Schmidt, T., Schmid-Burgk, J., Rapino, F., Robertson, A., Cooper, M., Graf, T. and Hornung, (2016). Human monocytes engage an alternative inflammasome pathway. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cellsWest, Erin E., Arbore, Giuseppina, Robertson, Avril A.B., Klos, Andreas, Woodruff, Trent M., O’Neill, Luke A., Coll, Rebecca C., Sher, Alan, Leonard, Warren J., Köhl, Jörg, Monk, Pete, Cooper, Matthew A., Afzali, Behdad, Lachmann, Helen J., Cope, Andrew P., Mayer-Barber, Katrin and Kemper, Claudia (2016). Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cells. Immunology 2016™ Meeting, Seattle, WA United States, 13 - 17 May 2016. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.196.supp.58.6 |
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2016 Conference Publication Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetesKammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Butler, M. S., Roberston, A. A. B., O'Neill, L. A., Murphy, A. J., Cooper, M. A. and Febbraio, M. A. (2016). Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetes. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Nlrp3 Inflammasome-Mediated, Il-1 beta-Dependent Inflammatory Responses Drive Severe, Steroid-Insensitive AsthmaKim, R. Y., Pinkerton, J. W., Essilfie, A. -T., Robertson, A. A., Baines, K. J., Mayall, J. R., Starkey, M. R., Wark, P. A., Gibson, P. G., O'Neill, L. A., Cooper, M. A., Horvat, J. C. and Hansbro, P. M. (2016). Nlrp3 Inflammasome-Mediated, Il-1 beta-Dependent Inflammatory Responses Drive Severe, Steroid-Insensitive Asthma. International Conference of the American Thoracic Society (ATS), San Francisco, California, 13-18 May 2016 . New York, NY, United States: American Thoracic Society. |
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2016 Conference Publication The NLRP3 inflammasome negatively regulates type 2 immunity to gastrointestinal helminth infectionAlhallaf, R., Agha, Z., Miller, C. M., Robertson, A. A., Dent, L. A., Cooper, M. A., Masters, S. L., Smith, N. C., Loukas, A. and Giacomin, P. R. (2016). The NLRP3 inflammasome negatively regulates type 2 immunity to gastrointestinal helminth infection. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200 |