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2023 Journal Article A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragmentsLi, Junrong, Howard, Christopher B., Dey, Shuvashis, Lowry, Kym, Whiley, David M., Puttick, Simon, Rose, Stephen, Lobb, Richard J., Wuethrich, Alain, Edwardraja, Selvakumar and Trau, Matt (2023). A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments. Nature Nanotechnology, 18 (10), 1222-1229. doi: 10.1038/s41565-023-01415-1 |
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2023 Journal Article Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemiaMoles, Ernest, Howard, Christopher B., Huda, Pie, Karsa, Mawar, McCalmont, Hannah, Kimpton, Kathleen, Duly, Alastair, Chen, Yongjuan, Huang, Yizhou, Tursky, Melinda L., Ma, David, Bustamante, Sonia, Pickford, Russell, Connerty, Patrick, Omari, Sofia, Jolly, Christopher J., Joshi, Swapna, Shen, Sylvie, Pimanda, John E., Dolnikov, Alla, Cheung, Laurence C., Kotecha, Rishi S., Norris, Murray D., Haber, Michelle, de Bock, Charles E., Somers, Klaartje, Lock, Richard B., Thurecht, Kristofer J. and Kavallaris, Maria (2023). Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia. Science Translational Medicine, 15 (696) abm1262, 1-17. doi: 10.1126/scitranslmed.abm1262 |
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2023 Journal Article A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concernVedelago, Courtney, Li, Junrong, Lowry, Kym, Howard, Christopher, Wuethrich, Alain and Trau, Matt (2023). A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern. ACS Sensors, 8 (4), 1648-1657. doi: 10.1021/acssensors.2c02782 |
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2026 Journal Article A digital SERS platform powered by bispecific antibody fragments for SARS-CoV-2 diagnosticsWang, Jing, Zhou, Quan, Lowry, Kym, Howard, Christopher B. and Trau, Matt (2026). A digital SERS platform powered by bispecific antibody fragments for SARS-CoV-2 diagnostics. Biosensors and Bioelectronics, 294 118252, 1-6. doi: 10.1016/j.bios.2025.118252 |
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2026 Journal Article Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effectWei, Xiaoli, Ding, Tianhao, Xi, Meili, Thurecht, Kristofer J., Howard, Christopher B., Cui, Jiwei, Zhan, Changyou and Zhang, Zui (2026). Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect. Nano Today, 66 102923, 102923. doi: 10.1016/j.nantod.2025.102923 |
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2025 Journal Article Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivoChu, Weijing, Ediriweera, Gayathri R., Prior, Amber, Huda, Pie, Lum, Benedict, Howard, Christopher B., Fletcher, Nicholas L., Bernhardt, Paul V. and Thurecht, Kristofer J. (2025). Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivo. Biomacromolecules acs.biomac.5c01157. doi: 10.1021/acs.biomac.5c01157 |
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2025 Journal Article Programmable dual‐targeting nano bioconjugates: a universal bioconjugation strategy to enhance single molecule proteomic assaysFarokhinejad, Fahimeh, Anderson, Will, Niu, Xueming, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2025). Programmable dual‐targeting nano bioconjugates: a universal bioconjugation strategy to enhance single molecule proteomic assays. Small Methods e01235, e01235. doi: 10.1002/smtd.202501235 |
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2025 Journal Article Evaluating mRNA Delivery Using Nuclear MedicineHumphries, James, Witjaksono, Andrea, Poudel, Abishek, Mardon, Karine, Migotto, Mary-anne, Cheetham, Seth, Howard, Christopher and Thurecht, Kristofer (2025). Evaluating mRNA Delivery Using Nuclear Medicine. Nuclear Medicine and Biology, 150-151 109117, 109117. doi: 10.1016/j.nucmedbio.2025.109117 |
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2025 Journal Article Physicochemical Tuning of Bispecific Antibody Fragment Immobilization for Robust Digital SERS BiosensingWang, Jing, Zhou, Quan, Howard, Christopher B. and Trau, Matt (2025). Physicochemical Tuning of Bispecific Antibody Fragment Immobilization for Robust Digital SERS Biosensing. Analytical Chemistry, 97 (43) acs.analchem.5c03980, 23994-24002. doi: 10.1021/acs.analchem.5c03980 |
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2025 Journal Article Exploiting the geranylgeranyl-pyrophosphate-sensing N-terminal domain of HMG-CoA reductase 2 to regulate farnesyl pyrophosphate synthase (Erg20p) for improved monoterpene production in Saccharomyces cerevisiaeLu, Zeyu, Evans, Samuel, McDonnell, Liam, Bandari, Naga Chandra, Weng, Yilun, Jin, Wanli, Speight, Robert, Schenk, Gerhard, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2025). Exploiting the geranylgeranyl-pyrophosphate-sensing N-terminal domain of HMG-CoA reductase 2 to regulate farnesyl pyrophosphate synthase (Erg20p) for improved monoterpene production in Saccharomyces cerevisiae. Yeast, 42 (8-10), 169-180. doi: 10.1002/yea.4005 |
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2025 Journal Article Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markersDietmair, Bettina, Humphries, James, Mercer, Timothy R., Thurecht, Kristofer J., Howard, Christopher B. and Cheetham, Seth W. (2025). Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers. Molecular Therapy Nucleic Acids, 36 (2) 102520, 1-7. doi: 10.1016/j.omtn.2025.102520 |
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2025 Journal Article Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancerLiu, Feifei, Howard, Christopher B., Huda, Pie, Fletcher, Nicholas L., Bell, Craig A., Blakey, Idriss, Agrez, Michael and Thurecht, Kristofer J. (2025). Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancer. Biomaterials, 317 123089, 1-14. doi: 10.1016/j.biomaterials.2025.123089 |
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2025 Journal Article Development and application of multivalent nanobody-functionalized plasmonic probes in SERS sensing platformsWang, Jing, Zhou, Quan, Lowry, Kym, Howard, Christopher B. and Trau, Matt (2025). Development and application of multivalent nanobody-functionalized plasmonic probes in SERS sensing platforms. Biosensors and Bioelectronics, 278 117292, 117292. doi: 10.1016/j.bios.2025.117292 |
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2025 Journal Article Multiplexing label-free polymeric nanocarriers via antipolymer antibodiesHumphries, James, Hobson-Peters, Jody, Ghosh, Saikat, Howard, Christopher B., Huda, Pie, Bell, Craig A., Fletcher, Nicholas L., Kempe, Kristian and Thurecht, Kristofer J. (2025). Multiplexing label-free polymeric nanocarriers via antipolymer antibodies. ACS Sensors, 10 (2), 1280-1288. doi: 10.1021/acssensors.4c03184 |
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2025 Journal Article Application of chimeric antigens to paper-based diagnostics for detection of West Nile virus infections of Crocodylus porosus – A novel animal test caseJohnston, Ryan A., Habarugira, Gervais, Harrison, Jessica J., Isberg, Sally R., Moran, Jasmin, Morgan, Mahali S., Davis, Steven S., Melville, Lorna, Howard, Christopher B., Henry, Charles S., Macdonald, Joanne, Bielefeldt-Ohmann, Helle, Hall, Roy A. and Hobson-Peters, Jody (2025). Application of chimeric antigens to paper-based diagnostics for detection of West Nile virus infections of Crocodylus porosus – A novel animal test case. Sensors and Actuators B: Chemical, 422 136611, 1-11. doi: 10.1016/j.snb.2024.136611 |
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2024 Journal Article A novel immunomodulating peptide with potential to complement oligodeoxynucleotide-mediated adjuvanticity in vaccination strategiesAgrez, Michael, Chandler, Christopher, Thurecht, Kristofer J., Fletcher, Nicholas L., Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew M., Gooding, Hayley and Gallagher, Laura (2024). A novel immunomodulating peptide with potential to complement oligodeoxynucleotide-mediated adjuvanticity in vaccination strategies. Scientific Reports, 14 (1) 26737, 1-17. doi: 10.1038/s41598-024-78150-7 |
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2024 Journal Article mRNA display pipeline for protein biosensor constructionCui, Zhenling, Ayva, Cagla Ergun, Liew, Yi Jin, Guo, Zhong, Mutschler, Roxane, Dreier, Birgit, Fiorito, Maria M., Walden, Patricia, Howard, Christopher B., Ely, Fernanda, Plückthun, Andreas, Pretorius, Carel, Ungerer, Jacobus P.J., Buckle, Ashley M. and Alexandrov, Kirill (2024). mRNA display pipeline for protein biosensor construction. ACS Sensors, 9 (6), 2846-2857. doi: 10.1021/acssensors.3c02471 |
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2024 Journal Article LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiaeLu, Zeyu, Shen, Qianyi, Bandari, Naga Chandra, Evans, Samuel, Mcdonnell, Liam, Liu, Lian, Jin, Wanli, Luna-Flores, Carlos Horacio, Collier, Thomas, Talbo, Gert, Mccubbin, Tim, Esquirol, Lygie, Myers, Chris, Trau, Matt, Dumsday, Geoff, Speight, Robert, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2024). LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae. Nucleic Acids Research, 52 (12) gkae460, 7367-7383. doi: 10.1093/nar/gkae460 |
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2024 Journal Article EGFR targeting of liposomal doxorubicin improves recognition and suppression of non-small cell lung cancerMoles, Ernest, Chang, David, Mansfeld, Friederike, Duly, Alastair, Kimpton, Kathleen, Logan, Amy, Howard, Christopher, Thurecht, Kristofer and Kavallaris, Maria (2024). EGFR targeting of liposomal doxorubicin improves recognition and suppression of non-small cell lung cancer. International Journal of Nanomedicine, 2024 (19), 3623-3639. doi: 10.2147/ijn.s450534 |
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2024 Journal Article Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastomaLogan, Amy, Howard, Christopher B., Huda, Pie, Kimpton, Kathleen, Ma, Zerong, Thurecht, Kristofer J., McCarroll, Joshua A., Moles, Ernest and Kavallaris, Maria (2024). Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma. Journal of Controlled Release, 367, 806-820. doi: 10.1016/j.jconrel.2024.02.007 |
