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2014 Journal Article Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG miceBenham, Helen, Rehaume, Linda M., Hasnain, Sumaira Z., Velasco, Jared, Baillet, Athan C., Ruutu, Merja, Kikly, Kristine, Wang, Ran, Tseng, Hsu-Wen, Thomas, Gethin P., Brown, Matthew A., Strutton, Geoffrey, McGuckin, Michael A. and Thomas, Ranjeny (2014). Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis and Rheumatology, 66 (7), 1755-1767. doi: 10.1002/art.38638 |
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2014 Journal Article Functional divergence in gastrointestinal microbiota in physically-separated genetically identical miceRogers, G. B., Kozlowska, J., Keeble, J., Metcalfe, K., Fao, M., Dowd, S. E., Mason, A. J., McGuckin, M. A. and Bruce, K. D. (2014). Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice. Scientific Reports, 4 (1) 5437. doi: 10.1038/srep05437 |
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2014 Journal Article A novel microbiota stratification system predicts future exacerbations in bronchiectasisRogers, Geraint B., Zain, Nur Masirah M., Bruce, Kenneth D., Burr, Lucy D., Chen, Alice C., Rivett, Damian W., McGuckin, Michael A. and Serisier, David J. (2014). A novel microbiota stratification system predicts future exacerbations in bronchiectasis. Annals of the American Thoracic Society, 11 (4), 496-503. doi: 10.1513/AnnalsATS.201310-335OC |
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2014 Conference Publication IL-22 May Maintain Colonic Mucosal Barrier Function by Overriding ROS-Induced ER Stress and Chemokine Production in Colonic Epithelial CellsLourie, Rohan, Hasnain, Sumaira Z., McGuckin, Michael A. and Florin, Timothy H. (2014). IL-22 May Maintain Colonic Mucosal Barrier Function by Overriding ROS-Induced ER Stress and Chemokine Production in Colonic Epithelial Cells. Digestive Disease Week 2014, Chicago, Illinois, 3-6 May 2014. Maryland Heights, MO, United States: W.B. Saunders Co.. |
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2014 Conference Publication Clinical Benefits of Long-Term, Low-Dose Erythromycin in Bronchiectasis Are Not Due to Modulation of Sputum Mucin ContentChen, A., Martin, M., Lourie, R., Burr, L., Hasnain, S., Bowler, S., Mcguckin, M. and Serisier, D. (2014). Clinical Benefits of Long-Term, Low-Dose Erythromycin in Bronchiectasis Are Not Due to Modulation of Sputum Mucin Content. Annual Scientific Meeting of the Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science 2014, Adelaide, SA Australia, 4-9 April 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12263_6 |
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2014 Conference Publication Direct Adverse Effects of IL-23 on Epithelial Cells Underline Greater Efficacy of Neutralizing IL-23 in Suppressing Murine ColitisWang, Ran, Hasnain, Sumaira Z., Tong, Hui, Lourie, Rohan, Florin, Timothy H. and McGuckin, Michael A. (2014). Direct Adverse Effects of IL-23 on Epithelial Cells Underline Greater Efficacy of Neutralizing IL-23 in Suppressing Murine Colitis. 55th Annual Meeting of the Society for Surgery of the Alimentary Tract (SSAT) / Digestive Disease Week (DDW), Chicago, Il, United States, May 03-06, 2014. Maryland Heights, MO, United States: W.B. Saunders Co.. doi: 10.1016/S0016-5085(14)62987-5 |
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2014 Conference Publication Human Neutrophil Elastase Activity and Matrix Metalloproteinase Activity Are Markers of Disease Severity in Non-Cf BronchiectasisChen, A., Lourie, R., Martin, M., Burr, L., Hasnain, S., Fantino, E., Bowler, S., Mcguckin, M. and Serisier, D. (2014). Human Neutrophil Elastase Activity and Matrix Metalloproteinase Activity Are Markers of Disease Severity in Non-Cf Bronchiectasis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2014 Annual Scientific Meetings, Adelaide Australia, 4-9 April 2014. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12263_6 |
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2014 Conference Publication IL-23 and IL-24 Upregulate Pro-Inflammatory Chemokine Genes in Colonic Epithelial CellsLourie, R., Hasnain, S. Z., McGuckin, M. A. and Florin, T. H. (2014). IL-23 and IL-24 Upregulate Pro-Inflammatory Chemokine Genes in Colonic Epithelial Cells. 103rd Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), San Diego, California, 1-7 March 2014. London, United Kingdom: Nature Publishing Group. |
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2014 Conference Publication Is geographic variability of incidence and prevalence of Crohn's Disease linked to Helicobacter pylori? An ecologic studyShah, A., Talley, N. J., Walker, M., Koloski, N., Shanahan, E. R., Morrison, M., Burger, D., Andrews, J. M., Mcguckin, M., Jones, M. and Holtmann, G. (2014). Is geographic variability of incidence and prevalence of Crohn's Disease linked to Helicobacter pylori? An ecologic study. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22-24 October 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736_6 |
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2014 Conference Publication Peroxisome Proliferator Activated Receptor. Gene Expression In The Airways Of Non Cystic Fibrosis Bronchiectasis Subjects Is Lower Than Healthy Controls And Inversely Correlated To Total Pseudomonas AerugINOSa Bacterial Load At Baseline Entry Into A Clinical TrialBurr, L. D., Rogers, G., Chen, A., McGuckin, M. and Serisier, D. J. (2014). Peroxisome Proliferator Activated Receptor. Gene Expression In The Airways Of Non Cystic Fibrosis Bronchiectasis Subjects Is Lower Than Healthy Controls And Inversely Correlated To Total Pseudomonas AerugINOSa Bacterial Load At Baseline Entry Into A Clinical Trial. NEW YORK: AMER THORACIC SOC. |
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2014 Journal Article Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cellsSpeckmann, Bodo, Gerloff, Kirsten, Simms, Lisa, Oancea, Iulia, Shi, Wei, McGuckin, Michael A., Radford-Smith, Graham and Khanna, Kum Kum (2014). Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells. Free Radical Biology and Medicine, 67, 265-277. doi: 10.1016/j.freeradbiomed.2013.11.001 |
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2013 Conference Publication Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil RecoveryWinkler, Ingrid G., Barbier, Valerie, Nutt, Heather L., Hasnain, Sumaira Z., Levesque, Jean-Pierre, Magnani, John L. and McGuckin, Michael A. (2013). Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil Recovery. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY. |
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2013 Journal Article Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucinsWalsh, Michael D., Cummings, Margaret C., Pearson, Sally-Ann, Clendenning, Mark, Walters, Rhiannon J., Nagler, Belinda, Hopper, John L., Jenkins, Mark A., Suthers, Graeme K., Goldblatt, Jack, Tucker, Kathy, Gattas, Michael R., Arnold, Julie L., Parry, Susan, Macrae, Finlay A., McGuckin, Michael A., Young, Joanne P. and Buchanan, Daniel D. (2013). Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins. Modern Pathology, 26 (7), 944-954. doi: 10.1038/modpathol.2012.232 |
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2013 Journal Article Gastrointestinal cell lines form polarized epithelia with an adherent mucus layer when cultured in semi-wet interfaces with mechanical stimulationNavabi, Nazanin, McGuckin, Michael A. and Linden, Sara K. (2013). Gastrointestinal cell lines form polarized epithelia with an adherent mucus layer when cultured in semi-wet interfaces with mechanical stimulation. PLoS One, 8 (7) e68761, e68761.1-e68761.15. doi: 10.1371/journal.pone.0068761 |
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2013 Journal Article Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteinsDas, Indrajit, Png, Chin Wen, Oancea, Iulia, Hasnain, Sumaira Z., Lourie, Rohan, Proctor, Martina, Eri, Rajaraman D., Sheng, Yong, Crane, Denis I., Florin, Timothy H. and McGuckin, Michael A. (2013). Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. Journal of Experimental Medicine, 210 (6), 1201-1216. doi: 10.1084/jem.20121268 |
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2013 Journal Article MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuliSheng, Y. H., Triyana, S., Wang, R., Das, I., Gerloff, K., Florin, T. H., Sutton, P. and McGuckin, M. A. (2013). MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuli. Mucosal Immunology, 6 (3), 557-568. doi: 10.1038/mi.2012.98 |
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2013 Journal Article A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion systemGorrell, Rebecca J., Guan, Jyeswei, Xin, Yue, Tafreshi, Mona Anoushiravani, Hutton, Melanie L., McGuckin, Michael A., Ferrero, Richard L. and Kwok, Terry (2013). A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system. Cellular Microbiology, 15 (4), 554-570. doi: 10.1111/cmi.12055 |
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2013 Journal Article Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in miceSina, Christian, Lipinski, Simone, Gavrilova, Olga, Aden, Konrad, Rehman, Ateequr, Till, Andreas, Rittger, Andrea, Podschun, Rainer, Meyer-Hoffert, Ulf, Haesler, Robert, Midtling, Emilie, Puetsep, Katrin, McGuckin, Michael A., Schreiber, Stefan, Saftig, Paul and Rosenstiel, Philip (2013). Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice. Gut, 62 (4), 520-530. doi: 10.1136/gutjnl-2011-300076 |
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2013 Journal Article A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicityOancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013). A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 (4), 594-605. doi: 10.1136/gutjnl-2012-302274 |
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2013 Journal Article Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trialSerisier, David J., Martin, Megan L., McGuckin, Michael A., Lourie, Rohan, Chen, Alice C., Brain, Barbara, Biga, Sally, Schlebusch, Sanmarié, Dash, Peter and Bowler, Simon D. (2013). Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. JAMA: The Journal of the American Medical Association, 309 (12), 1260-1267. doi: 10.1001/jama.2013.2290 |
