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2022

Journal Article

Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution

Kelderman, Cormac A. A., Davey, Patrick R. W. J., Ma, Michelle T., de Veer, Michael, Salimova, Ekaterina, Donnelly, Paul S. and Paterson, Brett M. (2022). Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution. Dalton Transactions, 51 (37), 14064-14078. doi: 10.1039/d2dt01264b

Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution

2021

Journal Article

The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes

Grieve, Melyssa L., Davey, Patrick R. W. J., Forsyth, Craig M. and Paterson, Brett M. (2021). The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes. Molecules, 26 (12) 3646, 3646. doi: 10.3390/molecules26123646

The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes

2020

Journal Article

An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals

Lange, Jaclyn L., Davey, Patrick R. W. J., Ma, Michelle T., White, Jonathan M., Morgenstern, Alfred, Bruchertseifer, Frank, Blower, Philip J. and Paterson, Brett M. (2020). An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals. Dalton Transactions, 49 (42), 14962-14974. doi: 10.1039/d0dt02673e

An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals

2019

Journal Article

Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups

Paterson, Brett M., Cullinane, Carleen, Crouch, Peter J., White, Anthony R., Barnham, Kevin J., Roselt, Peter D., Noonan, Wayne, Binns, David, Hicks, Rodney J. and Donnelly, Paul S. (2019). Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups. Inorganic Chemistry, 58 (7), 4540-4552. doi: 10.1021/acs.inorgchem.9b00117

Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups

2019

Journal Article

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

2019

Journal Article

Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging

Imberti, Cinzia, Chen, Yu-Lin, Foley, Calum A., Ma, Michelle T., Paterson, Brett M., Wang, Yifu, Young, Jennifer D., Hider, Robert C. and Blower, Philip J. (2019). Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging. Dalton Transactions, 48 (13), 4299-4313. doi: 10.1039/c8dt04454f

Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging

2018

Journal Article

64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy

Hicks, Rodney J., Jackson, Price, Kong, Grace, Ware, Robert E., Hofman, Michael S., Pattison, David A., Akhurst, Timothy A., Drummond, Elizabeth, Roselt, Peter, Callahan, Jason, Price, Roger, Jeffery, Charmaine M., Hong, Emily, Noonan, Wayne, Herschtal, Alan, Hicks, Lauren J., Hedt, Amos, Harris, Matthew, Paterson, Brett M. and Donnelly, Paul S. (2018). 64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy. Journal of Nuclear Medicine, 60 (6), 777-785. doi: 10.2967/jnumed.118.217745

64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy

2017

Journal Article

Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling

Tsionou, Maria Iris, Knapp, Caroline E., Foley, Calum A., Munteanu, Catherine R., Cakebread, Andrew, Imberti, Cinzia, Eykyn, Thomas R., Young, Jennifer D., Paterson, Brett M., Blower, Philip J. and Ma, Michelle T. (2017). Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling. RSC Advances, 7 (78), 49586-49599. doi: 10.1039/c7ra09076e

Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling

2017

Journal Article

Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes. Angewandte Chemie International Edition, 56 (29). doi: 10.1002/anie.201782961

Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

2017

Journal Article

Frontispiz: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Frontispiz: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes. Angewandte Chemie, 129 (29). doi: 10.1002/ange.201782961

Frontispiz: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

2017

Journal Article

Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes. Angewandte Chemie - International Edition, 56 (29), 8370-8374. doi: 10.1002/anie.201701596

Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes

2017

Journal Article

Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes. Angewandte Chemie, 129 (29), 8490-8494. doi: 10.1002/ange.201701596

Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

2016

Journal Article

Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets

Ziegler, Melanie, Alt, Karen, Paterson, Brett M., Kanellakis, Peter, Bobik, Alex, Donnelly, Paul S., Hagemeyer, Christoph E. and Peter, Karlheinz (2016). Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets. Scientific Reports, 6 (1) 38161. doi: 10.1038/srep38161

Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets

2016

Conference Publication

First-Time-in-Human Trial of Cu-64 MeCOSAR-octreotate (CuSARTATE) for Imaging and Dosimetry Estimation in Neuroendocrine Tumor (NET)

Hicks, Rodney, Jackson, Price, Ware, Robert, Drummond, Elizabeth, Roselt, Peter, Noonan, Wayne, Price, Roger, Jeffrey, Charmaine, Callahan, Jason, Hong, Emily, Hicks, Lauren, Hedt, Amos, Paterson, Brett, Kong, Grace and Donnelly, Paul (2016). First-Time-in-Human Trial of Cu-64 MeCOSAR-octreotate (CuSARTATE) for Imaging and Dosimetry Estimation in Neuroendocrine Tumor (NET). RESTON: SOC NUCLEAR MEDICINE INC.

First-Time-in-Human Trial of Cu-64 MeCOSAR-octreotate (CuSARTATE) for Imaging and Dosimetry Estimation in Neuroendocrine Tumor (NET)

2016

Book Chapter

Macrocyclic bifunctional chelators and conjugation strategies for copper-64 radiopharmaceuticals

Paterson, Brett M. and Donnelly, Paul S. (2016). Macrocyclic bifunctional chelators and conjugation strategies for copper-64 radiopharmaceuticals. Insights from Imaging in Bioinorganic Chemistry. (pp. 223-251) edited by Rudi van Eldik and Colin D. Hubbard. San Diego, CA United States: Academic Press. doi: 10.1016/bs.adioch.2015.09.005

Macrocyclic bifunctional chelators and conjugation strategies for copper-64 radiopharmaceuticals

2015

Journal Article

Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer

Gourni, Eleni, Del Pozzo, Luigi, Kheirallah, Emilie, Smerling, Christiane, Waser, Beatrice, Reubi, Jean-Claude, Paterson, Brett M., Donnelly, Paul S., Meyer, Philipp T. and Maecke, Helmut R. (2015). Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer. Molecular Pharmaceutics, 12 (8), 2781-2790. doi: 10.1021/mp500671j

Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer

2015

Journal Article

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

Alt, Karen, Paterson, Brett M., Westein, Erik, Rudd, Stacey E., Poniger, Stan S., Jagdale, Shweta, Ardipradja, Katie, Connell, Timothy U., Krippner, Guy Y., Nair, Ashish K. N., Wang, Xiaowei, Tochon-Danguy, Henri J., Donnelly, Paul S., Peter, Karlheinz and Hagemeyer, Christoph E. (2015). A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry. Angewandte Chemie - International Edition, 54 (26), 7515-7519. doi: 10.1002/anie.201411507

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

2015

Journal Article

The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution

Dearling, Jason L. J., Paterson, Brett M., Akurathi, Vamsidhar, Betanzos-Lara, Soledad, Treves, S. Ted, Voss, Stephan D., White, Jonathan M., Huston, James S., Smith, Suzanne V., Donnelly, Paul S. and Packard, Alan B. (2015). The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution. Bioconjugate Chemistry, 26 (4), 707-717. doi: 10.1021/acs.bioconjchem.5b00049

The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution

2015

Journal Article

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B

Ma, Michelle T., Meszaros, Levente K., Paterson, Brett M., Berry, David J., Cooper, Maggie S., Ma, Yongmin, Hider, Robert C. and Blower, Philip J. (2015). Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B. Dalton Transactions, 44 (11), 4884-4900. doi: 10.1039/c4dt02978j

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B

2015

Journal Article

Engineering poly(ethylene glycol) particles for improved biodistribution

Cui, Jiwei, De Rose, Robert, Alt, Karen, Alcantara, Sheilajen, Paterson, Brett M., Liang, Kang, Hu, Ming, Richardson, Joseph J., Yan, Yan, Jeffery, Charmaine M., Price, Roger I., Peter, Karlheinz, Hagemeyer, Christoph E., Donnelly, Paul S., Kent, Stephen J. and Caruso, Frank (2015). Engineering poly(ethylene glycol) particles for improved biodistribution. ACS Nano, 9 (2), 1571-1580. doi: 10.1021/nn5061578

Engineering poly(ethylene glycol) particles for improved biodistribution