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2026

Journal Article

Saxiphilin functions as a toxin sponge protein that counteracts the effects of saxitoxin poisoning

Nixon, Samantha A., Zakrzewska, Sandra, Jang, Seil, Huang, Keli, Bara, Anissa, Chen, Zhou, Goss, Daynen R., Park, Elizabeth R., Du Bois, J. and Minor, Daniel L. (2026). Saxiphilin functions as a toxin sponge protein that counteracts the effects of saxitoxin poisoning. Nature Communications, 17 (1) 5934, 1-15. doi: 10.1038/s41467-026-75136-z

Saxiphilin functions as a toxin sponge protein that counteracts the effects of saxitoxin poisoning

2025

Journal Article

Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins

Zakrzewska, Sandra, Nixon, Samantha A., Chen, Zhou, Hajare, Holly S., Park, Elizabeth R., Mulcahy, John V., Arlinghaus, Kandis M., Neu, Eduard, Konovalov, Kirill, Provasi, Davide, Leighfield, Tod A., Filizola, Marta, Du Bois, J. and Minor, Daniel L. (2025). Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins. Nature Communications, 16 (1) 3885, 1-16. doi: 10.1038/s41467-025-58903-2

Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins

2025

Journal Article

A review of the venom microbiome and its utility in ecology and evolution including future directions for emerging research

De León, Marina E., Fox, Eduardo G. P., Dunaj, Sara, Jenner, Ronald A., Keiser, Carl N., Macrander, Jason, Nixon, Samantha A., Nobile, Clarissa J., Petras, Daniel, Rodriguez-Roman, Eduardo, Saviola, Anthony J., Trim, Steven A., Varona, Natascha S., Yeager, Justin, Ul-Hasan, Sabah, Herzig, Volker and Colston, Timothy J. (2025). A review of the venom microbiome and its utility in ecology and evolution including future directions for emerging research. Symbiosis, 95 (1), 3-27. doi: 10.1007/s13199-024-01031-0

A review of the venom microbiome and its utility in ecology and evolution including future directions for emerging research

2023

Journal Article

Two novel mosquitocidal peptides isolated from the venom of the Bahia scarlet tarantula (Lasiodora klugi)

Ahmed, Jamila, Walker, Andrew A., Perdomo, Hugo D., Guo, Shaodong, Nixon, Samantha A., Vetter, Irina, Okoh, Hilary I., Shehu, Dalhatu M., Shuaibu, Mohammed N., Ndams, Iliya S., King, Glenn F. and Herzig, Volker (2023). Two novel mosquitocidal peptides isolated from the venom of the Bahia scarlet tarantula (Lasiodora klugi). Toxins, 15 (7) 418, 1-14. doi: 10.3390/toxins15070418

Two novel mosquitocidal peptides isolated from the venom of the Bahia scarlet tarantula (Lasiodora klugi)

2021

Journal Article

Multipurpose peptides: the venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities

Nixon, Samantha A., Robinson, Samuel D., Agwa, Akello J., Walker, Andrew A., Choudhary, Shivani, Touchard, Axel, Undheim, Eivind A.B., Robertson, Alan, Vetter, Irina, Schroeder, Christina I., Kotze, Andrew C., Herzig, Volker and King, Glenn F. (2021). Multipurpose peptides: the venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. Biochemical Pharmacology, 192 114693, 114693. doi: 10.1016/j.bcp.2021.114693

Multipurpose peptides: the venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities

2021

Journal Article

Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans

Walker, Andrew A., Robinson, Samuel D., Paluzzi, Jean-Paul V., Merritt, David J., Nixon, Samantha A., Schroeder, Christina I., Jin, Jiayi, Goudarzi, Mohaddeseh Hedayati, Kotze, Andrew C., Dekan, Zoltan, Sombke, Andy, Alewood, Paul F., Fry, Bryan G., Epstein, Marc E., Vetter, Irina and King, Glenn F. (2021). Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans. Proceedings of the National Academy of Sciences of the United States of America, 118 (18) 2023815118, e2023815118. doi: 10.1073/pnas.2023815118

Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans

2020

Journal Article

Where are all the anthelmintics? Challenges and opportunities on the path to new anthelmintics

Nixon, Samantha A., Welz, Claudia, Woods, Debra J., Costa-Junior, Livio, Zamanian, Mostafa and Martin, Richard J. (2020). Where are all the anthelmintics? Challenges and opportunities on the path to new anthelmintics. International Journal for Parasitology: Drugs and Drug Resistance, 14, 8-16. doi: 10.1016/j.ijpddr.2020.07.001

Where are all the anthelmintics? Challenges and opportunities on the path to new anthelmintics

2020

Journal Article

It takes two: dimerization is essential for the broad-spectrum predatory and defensive activities of the venom peptide Mp1a from the jack jumper ant Myrmecia pilosula

Nixon, Samantha A., Dekan, Zoltan, Robinson, Samuel D., Guo, Shaodong, Vetter, Irina, Kotze, Andrew C., Alewood, Paul F., King, Glenn F. and Herzig, Volker (2020). It takes two: dimerization is essential for the broad-spectrum predatory and defensive activities of the venom peptide Mp1a from the jack jumper ant Myrmecia pilosula. Biomedicines, 8 (7) 185, 1-13. doi: 10.3390/biomedicines8070185

It takes two: dimerization is essential for the broad-spectrum predatory and defensive activities of the venom peptide Mp1a from the jack jumper ant Myrmecia pilosula

2020

Journal Article

Animal toxins — Nature's evolutionary-refined toolkit for basic research and drug discovery

Herzig, Volker, Cristofori-Armstrong, Ben, Israel, Mathilde R., Nixon, Samantha A., Vetter, Irina and King, Glenn F. (2020). Animal toxins — Nature's evolutionary-refined toolkit for basic research and drug discovery. Biochemical Pharmacology, 181 114096, 114096. doi: 10.1016/j.bcp.2020.114096

Animal toxins — Nature's evolutionary-refined toolkit for basic research and drug discovery

2019

Journal Article

The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro

Nixon, Samantha A., Saez, Natalie J., Herzig, Volker, King, Glenn F. and Kotze, Andrew C. (2019). The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro. Veterinary Parasitology, 270, 40-46. doi: 10.1016/j.vetpar.2019.05.008

The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro