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2025 Journal Article The structural integrity of human TFF1 under reducing conditionsElmaci, Dilsah Nur, Hopping, Gene, Hoffmann, Werner, Muttenthaler, Markus and Stein, Matthias (2025). The structural integrity of human TFF1 under reducing conditions. Redox Biology, 81 103534, 103534. doi: 10.1016/j.redox.2025.103534 |
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2020 Journal Article A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive MoleculesCrook, Zachary R., Girard, Emily, Sevilla, Gregory P., Merrill, Morgan, Friend, Della, Rupert, Peter B., Pakiam, Fiona, Nguyen, Elizabeth, Yin, Chunfeng, Ruff, Raymond O., Hopping, Gene, Strand, Andrew D., Finton, Kathryn A. K., Coxon, Margo, Mhyre, Andrew J., Strong, Roland K. and Olson, James M. (2020). A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules. Journal of Molecular Biology, 432 (14), 3989-4009. doi: 10.1016/j.jmb.2020.04.002 |
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2020 Journal Article A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposureSangar, Michelle L. Cook, Girard, Emily J., Hopping, Gene, Yin, Chunfeng, Pakiam, Fiona, Brusniak, Mi-Youn, Nguyen, Elizabeth, Ruff, Raymond, Gewe, Mesfin M., Byrnes-Blake, Kelly, Nairn, Natalie W., Miller, Dennis M., Mehlin, Christopher, Strand, Andrew D., Mhyre, Andrew J., Correnti, Colin E., Strong, Roland K., Simon, Julian A. and Olson, James M. (2020). A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure. Science Translational Medicine, 12 (533) eaay1041. doi: 10.1126/scitranslmed.aay1041 |
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2018 Journal Article Pacifastin-derived Peptides Target Tumors for Use in In Vivo ImagingSottero, Theo L., Girard, Emily J., Myers, Carrie, Hopping, Gene, Mhyre, Andrew J. and Olson, James M. (2018). Pacifastin-derived Peptides Target Tumors for Use in In Vivo Imaging. Anticancer Research, 38 (1), 51-60. doi: 10.21873/anticanres.12191 |
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2016 Journal Article Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of SequenceKellock, Jackson, Hopping, Gene, Caughey, Byron and Daggett, Valerie (2016). Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence. Journal of Molecular Biology, 428 (11), 2317-2328. doi: 10.1016/j.jmb.2016.03.013 |
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2014 Journal Article Nature versus design: the conformational propensities of d-amino acids and the importance of side chain chiralityTowse, Clare-Louise, Hopping, Gene, Vulovic, Ivan and Daggett, Valerie (2014). Nature versus design: the conformational propensities of d-amino acids and the importance of side chain chirality. Protein Engineering Design and Selection, 27 (11), 447-455. doi: 10.1093/protein/gzu037 |
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2014 Journal Article Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomersHopping, Gene, Kellock, Jackson, Barnwal, Ravi Pratap, Law, Peter, Bryers, James, Varani, Gabriele, Caughey, Byron and Daggett, Valerie (2014). Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers. eLife, 2014 (3) e01681. doi: 10.7554/elife.01681 |
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2014 Journal Article Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptorsHopping, Gene, Wang, C-I Anderson, Hogg, Ron C., Nevin, Simon T., Lewis, Richard J., Adams, David J. and Alewood, Paul F. (2014). Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology, 91 (4), 534-542. doi: 10.1016/j.bcp.2014.07.025 |
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2013 Journal Article Designed Trpzip-3 beta-Hairpin Inhibits Amyloid Formation in Two Different Amyloid SystemsHopping, Gene, Kellock, Jackson, Caughey, Byron and Daggett, Valerie (2013). Designed Trpzip-3 beta-Hairpin Inhibits Amyloid Formation in Two Different Amyloid Systems. Acs Medicinal Chemistry Letters, 4 (9), 824-828. doi: 10.1021/ml300478w |
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2011 Journal Article Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted foldingDantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642 |
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2010 Journal Article Benzhydrylamine linker grafting: A strategy for the improved synthesis of C-terminal peptide amidesAlewood, Dianne, Hopping, Gene, Brust, Andreas, Reid, Robert C. and Alewood, Paul F. (2010). Benzhydrylamine linker grafting: A strategy for the improved synthesis of C-terminal peptide amides. Journal of Peptide Science, 16 (10), 551-557. doi: 10.1002/psc.1248 |
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2009 Journal Article Rapid access to omega conotoxin chimeras using native chemical ligationHopping , Gene, Lewis, Richard J. and Alewood, Paul F. (2009). Rapid access to omega conotoxin chimeras using native chemical ligation. Austalian Journal of Chemistry, 62 (10), 1333-1338. doi: 10.1071/CH09216 |
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2007 Journal Article AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivityDutertre, S., Ulens, C, Buttner, R, Fish, A, van Elk, R, Kendel, Y, Hopping, G., Alewood, P. F., Schroeder, C., Nicke, A, Smit, AB, Sixma, TK and Lewis, R. J. (2007). AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. Embo Journal, 26 (16), 3858-3867. doi: 10.1038/sj.emboj.7601785 |
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2007 Conference Publication Structural studies of AChBP, a soluble nicotinic acetylcholine receptor homolog, in complex with novel ligandsUlens, Chris, Dutertre, Sebastien, Hopping, Gene, Fish, Alex, Schroeder, Christina, van Elk, Rene, Akdemir, Atilla, de Esch, Iwan, Nicke, Annette, Alewood, Paul, Lewis, Richard, Smit, August B. and Perrakis, Anastassis (2007). Structural studies of AChBP, a soluble nicotinic acetylcholine receptor homolog, in complex with novel ligands. 51st Annual Meeting of the Biophysical Society, Baltimore, MD United States, 3-7 March 2007. Cambridge, United Kingdom: Cell Press. |
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2003 Journal Article alpha-conotoxins PnIA and [A10L] PnIA stabilize different states of the alpha 7-L247T nicotinic acetylcholine receptorHogg, R. C., Hopping, G., Alewood, P. F., Adams, D. J. and Bertrand, D. (2003). alpha-conotoxins PnIA and [A10L] PnIA stabilize different states of the alpha 7-L247T nicotinic acetylcholine receptor. Journal of Biological Chemistry, 278 (29), 26908-26914. doi: 10.1074/jbc.M212628200 |
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2003 Journal Article Marine toxins as sources of drug leadsAlewood, P., Hopping, G. and Armishaw, C. (2003). Marine toxins as sources of drug leads. Australian Journal of Chemistry, 56 (8), 769-774. doi: 10.1071/CH03043 |
