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2023 Journal Article A booster regime of liposome-delivered live-attenuated CHIKV vaccine RNA genome protects against chikungunya virus disease in miceRao, Shambhavi, Abeyratne, Eranga, Freitas, Joseph R., Yang, Chenying, Tharmarajah, Kothila, Mostafavi, Helen, Liu, Xiang, Zaman, Mehfuz, Mahalingam, Suresh, Zaid, Ali and Taylor, Adam (2023). A booster regime of liposome-delivered live-attenuated CHIKV vaccine RNA genome protects against chikungunya virus disease in mice. Vaccine, 41 (27), 3976-3988. doi: 10.1016/j.vaccine.2023.05.032 |
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2023 Journal Article Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion releaseLabzin, Larisa I., Chew, Keng Yih, Eschke, Kathrin, Wang, Xiaohui, Esposito, Tyron, Stocks, Claudia J., Rae, James, Patrick, Ralph, Mostafavi, Helen, Hill, Brittany, Yordanov, Teodor E., Holley, Caroline L., Emming, Stefan, Fritzlar, Svenja, Mordant, Francesca L., Steinfort, Daniel P., Subbarao, Kanta, Nefzger, Christian M., Lagendijk, Anne K., Gordon, Emma J., Parton, Robert G., Short, Kirsty R., Londrigan, Sarah L. and Schroder, Kate (2023). Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release. Science Signaling, 16 (782) eabq1366, eabq1366. doi: 10.1126/scisignal.abq1366 |
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2023 Journal Article Anti-inflammatory actions of Pentosan polysulfate sodium in a mouse model of influenza virus A/PR8/34-induced pulmonary inflammationKrishnan, Ravi, Stapledon, Catherine J. M., Mostafavi, Helen, Freitas, Joseph R., Liu, Xiang, Mahalingam, Suresh and Zaid, Ali (2023). Anti-inflammatory actions of Pentosan polysulfate sodium in a mouse model of influenza virus A/PR8/34-induced pulmonary inflammation. Frontiers in Immunology, 14 1030879. doi: 10.3389/fimmu.2023.1030879 |
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2022 Journal Article N-linked glycans shape skin immune responses during arthritis and myositis after intradermal infection with Ross River VirusTharmarajah, Kothila, Everest-Dass, Arun, Vider, Jelena, Liu, Xiang, Freitas, Joseph R., Mostafavi, Helen, Bettadapura, Jayaram, von Itzstein, Mark, West, Nicholas P., Taylor, Adam, Mahalingam, Suresh and Zaid, Ali (2022). N-linked glycans shape skin immune responses during arthritis and myositis after intradermal infection with Ross River Virus. Journal of Virology, 96 (17), 1-26. doi: 10.1128/jvi.00999-22 |
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2022 Journal Article The Delta SARS-CoV-2 variant of concern induces distinct pathogenic patterns of respiratory disease in K18-hACE2 transgenic mice compared to the ancestral strain from WuhanLiu, Xiang, Mostafavi, Helen, Ng, Wern Hann, Freitas, Joseph R., King, Nicholas J. C., Zaid, Ali, Taylor, Adam and Mahalingam, Suresh (2022). The Delta SARS-CoV-2 variant of concern induces distinct pathogenic patterns of respiratory disease in K18-hACE2 transgenic mice compared to the ancestral strain from Wuhan. mBio, 13 (3) e0068322, 1-16. doi: 10.1128/mbio.00683-22 |
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2022 Journal Article Interleukin-17 contributes to Chikungunya virus-induced diseaseLiu, Xiang, Poo, Yee-Suan, Alves, Juliana C., Almeida, Roque P., Mostafavi, Helen, Tang, Patrick Chun Hean, Bucala, Richard, Teixeira, Mauro M., Taylor, Adam, Zaid, Ali and Mahalingam, Suresh (2022). Interleukin-17 contributes to Chikungunya virus-induced disease. mBio, 13 (2) e00289-22. doi: 10.1128/mbio.00289-22 |
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2022 Journal Article Interleukin-17 contributes to Ross River virus-induced arthritis and myositisMostafavi, Helen, Tharmarajah, Kothila, Vider, Jelena, West, Nicholas P., Freitas, Joseph R., Cameron, Barbara, Foster, Paul S., Hueston, Linda P., Lloyd, Andrew R., Mahalingam, Suresh and Zaid, Ali (2022). Interleukin-17 contributes to Ross River virus-induced arthritis and myositis. PLoS Pathogens, 18 (2) e1010185, e1010185. doi: 10.1371/journal.ppat.1010185 |
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2020 Journal Article Liposomal delivery of the RNA genome of a live-attenuated chikungunya virus vaccine candidate provides local, but not systemic protection after one doseAbeyratne, Eranga, Tharmarajah, Kothila, Freitas, Joseph R, Mostafavi, Helen, Mahalingam, Suresh, Zaid, Ali, Zaman, Mehfuz and Taylor, Adam (2020). Liposomal delivery of the RNA genome of a live-attenuated chikungunya virus vaccine candidate provides local, but not systemic protection after one dose. Frontiers in immunology, 11 304. doi: 10.3389/fimmu.2020.00304 |
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2020 Journal Article Modulation of monocyte-driven myositis in alphavirus infection reveals a role for CX3CR1+ macrophages in tissue repairZaid, Ali, Tharmarajah, Kothila, Mostafavi, Helen, Freitas, Joseph R., Sheng, Kuo-Ching, Foo, Suan-Sin, Chen, Weiqiang, Vider, Jelena, Liu, Xiang, West, Nicholas P., Herrero, Lara J., Taylor, Adam, Mackay, Laura K., Getts, Daniel R., King, Nicholas J. C. and Mahalingam, Suresh (2020). Modulation of monocyte-driven myositis in alphavirus infection reveals a role for CX3CR1+ macrophages in tissue repair. mBio, 11 (2) e03353-19. doi: 10.1128/mBio.03353-19 |
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2019 Journal Article Arthritogenic alphavirus-induced immunopathology and targeting host inflammation as a therapeutic strategy for alphaviral diseaseMostafavi, Helen, Abeyratne, Eranga, Zaid, Ali and Taylor, Adam (2019). Arthritogenic alphavirus-induced immunopathology and targeting host inflammation as a therapeutic strategy for alphaviral disease. Viruses, 11 (3) 290, 290. doi: 10.3390/v11030290 |
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2018 Journal Article Chikungunya arthritis: implications of acute and chronic inflammation mechanisms on disease managementZaid, Ali, Gérardin, Patrick, Taylor, Adam, Mostafavi, Helen, Malvy, Denis and Mahalingam, Suresh (2018). Chikungunya arthritis: implications of acute and chronic inflammation mechanisms on disease management. Arthritis and Rheumatology, 70 (4), 484-495. doi: 10.1002/art.40403 |
