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2019

Conference Publication

Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients

Thomson, R., Scoleri, G., Taylor, S., Leong, L., Burr, L. and Rogers, G. (2019). Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients. International Conference of the American-Thoracic-Society, Dallas Tx, May 17-22, 2019. NEW YORK: AMER THORACIC SOC. doi: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1035

Relating Airway Microbiota Composition to Nontuberculous Mycobacterial Infections in Adult Bronchiectasis Patients

2018

Journal Article

Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut

Wang, Yanan, Leong, Lex E.X., Keating, Rebecca L., Kanno, Tokuwa, Abell, Guy C.J., Mobegi, Fredrick M., Choo, Jocelyn M., Wesselingh, Steve L., Mason, A. James, Burr, Lucy D. and Rogers, Geraint B. (2018). Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut. Gut Microbes, 10 (3), 1-15. doi: 10.1080/19490976.2018.1534512

Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut

2018

Journal Article

VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles

Keating, Dominic, Marigowda, Gautham, Burr, Lucy, Daines, Cori, Mall, Marcus A., McKone, Edward F., Ramsey, Bonnie W., Rowe, Steven M., Sass, Laura A., Tullis, Elizabeth, McKee, Charlotte M., Moskowitz, Samuel M., Robertson, Sarah, Savage, Jessica, Simard, Christopher, Van Goor, Fredrick, Waltz, David, Xuan, Fengjuan, Young, Tim and Taylor-Cousar, Jennifer L. (2018). VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles. New England Journal of Medicine, 379 (17), 1612-1620. doi: 10.1056/NEJMoa1807120

VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles

2018

Journal Article

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z. and McGuckin, Michael A. (2018). PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa. PLoS ONE, 13 (8) e0202296, e0202296. doi: 10.1371/journal.pone.0202296

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

2018

Journal Article

Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy

Taylor, Steven L., Leong, Lex E. X., Mobegi, Fredrick M., Choo, Jocelyn M., Burr, Lucy D., Wesselingh, Steve and Rogers, Geraint B. (2018). Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy. Multidisciplinary Respiratory Medicine, 13 (S1) 30, 30. doi: 10.1186/s40248-018-0140-9

Understanding the impact of antibiotic therapies on the respiratory tract resistome: a novel pooled-template metagenomic sequencing strategy

2018

Journal Article

Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis

Choo, Jocelyn M., Abell, Guy C. J., Thomson, Rachel, Morgan, Lucy, Waterer, Grant, Gordon, David L., Taylor, Steven L., Leong, Lex E. X., Wesselingh, Steve L., Burr, Lucy D. and Rogers, Geraint B. (2018). Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis. mSphere, 3 (2) e00103-18, e00103-18. doi: 10.1128/mSphere.00103-18

Impact of long-term erythromycin therapy on the oropharyngeal microbiome and resistance gene reservoir in non-cystic fibrosis bronchiectasis

2017

Other Outputs

An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis

Burr, Lucy Davina (2017). An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2017.836

An investigation into the effect of erythromycin on Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis

2017

Conference Publication

The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand

Visser, Simone, Allan, Heather, Burr, Lucy, Chang, Anne, Holmes-Liew, Chien-Li, Hunter, Cameron, Jackson, Dan, King, Paul, Maguire, Graeme, Middleton, Peter, Smith, Daniel, Thomson, Rachel, Waterer, Grant, Wong, Conroy and Morgan, Lucy (2017). The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Canberra, Australia, 24–28 March 2017. Richmond, VIC Australia: Wiley.

The Australasian Bronchiectasis Registry - Early Steps in Mapping the Impact of Bronchiectasis in Australia and New Zealand

2017

Conference Publication

The Australasian Bronchiectasis Registry - Early Steps In Mapping The Impact Of Bronchiectasis In Australia And New Zealand

Visser, S., Allan, H., Burr, L., Chang, A., Holmes-Liew, C. -L., Hunter, C., Jackson, D., King, P., Maguire, G., Middleton, P., Smith, D., Thomson, R., Waterer, G. W., Wong, C. and Morgan, L. (2017). The Australasian Bronchiectasis Registry - Early Steps In Mapping The Impact Of Bronchiectasis In Australia And New Zealand. International Conference of the American-Thoracic-Society (ATS), Washington Dc, May 19-24, 2017. NEW YORK: AMER THORACIC SOC.

The Australasian Bronchiectasis Registry - Early Steps In Mapping The Impact Of Bronchiectasis In Australia And New Zealand

2016

Journal Article

Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial

Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Hamilton, Brett R., Pool, Gertruida F., Taylor, Steven L., Venter, Deon, Bowler, Simon D., Biga, Sally and McGuckin, Michael A. (2016). Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial. Annals of the American Thoracic Society, 13 (10), 1697-1703. doi: 10.1513/AnnalsATS.201601-044OC

Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial

2016

Journal Article

Culture-independent detection of nontuberculous mycobacteria in clinical respiratory samples

Scoleri, Gianny P., Choo, Jocelyn M., Leong, Lex E. X., Goddard, Thomas R., Shephard, Lisa, Burr, Lucy D., Bastian, Ivan, Thomson, Rachel M. and Rogers, Geraint B. (2016). Culture-independent detection of nontuberculous mycobacteria in clinical respiratory samples. Journal of Clinical Microbiology, 54 (9), 2395-2398. doi: 10.1128/JCM.01410-16

Culture-independent detection of nontuberculous mycobacteria in clinical respiratory samples

2016

Journal Article

FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis

Taylor, Steven L., Woodman, Richard J., Chen, Alice C. H., Burr, Lucy D., Gordon, David L., McGuckin, Michael A., Wesselingh, Steve and Rogers, Geraint B. (2016). FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis. Thorax, 72 (4), 304-310. doi: 10.1136/thoraxjnl-2016-208775

FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis

2015

Journal Article

Matrix metalloproteinases vary with airway microbiota composition and lung function in non-cystic fibrosis bronchiectasis

Taylor, Steven L., Rogers, Geraint B., Chen, Alice C.-H., Burr, Lucy D., McGuckin, Michael A. and Serisier, David J. (2015). Matrix metalloproteinases vary with airway microbiota composition and lung function in non-cystic fibrosis bronchiectasis. Annals of the American Thoracic Society, 12 (5), 701-707. doi: 10.1513/AnnalsATS.201411-513OC

Matrix metalloproteinases vary with airway microbiota composition and lung function in non-cystic fibrosis bronchiectasis

2015

Journal Article

Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation

Chen, Alice C.-H., Martin, Megan L., Lourie, Rohan, Rogers, Geraint B., Burr, Lucy D., Hasnain, Sumaira Z., Bowler, Simon D., McGuckin, Michael A. and Serisier, David J. (2015). Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation. PLoS ONE, 10 (3) e0119325, e0119325. doi: 10.1371/journal.pone.0119325

Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation

2015

Conference Publication

Sub inhibitory erythromycin reduces the expression of key P. aeruginosa virulence determinants in vitro

Burr, L., Rogers, G., Taylor, S., McGuckin, M. and Serisier, D. (2015). Sub inhibitory erythromycin reduces the expression of key P. aeruginosa virulence determinants in vitro. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Gold Coast, Australia, 27 March – 1 April 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12495_14

Sub inhibitory erythromycin reduces the expression of key P. aeruginosa virulence determinants in vitro

2015

Conference Publication

Sub inhibitory erythromycin reduces the expression of key P. aeruginosa virulence determinants in non-CF bronchiectasis subjects

Burr, L., Rogers, G., Taylor, S., McGuckin, M. and Serisier, D. (2015). Sub inhibitory erythromycin reduces the expression of key P. aeruginosa virulence determinants in non-CF bronchiectasis subjects. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland Australia, Mar 27-Apr 01, 2015. Hoboken, NJ United States: Wiley-Blackwell.

Sub inhibitory erythromycin reduces the expression of key P. aeruginosa virulence determinants in non-CF bronchiectasis subjects

2015

Conference Publication

Collagen protease levels vary with airway microbiota composition and lung function in bronchiectasis

Taylor, S., Rogers, G., Chen, A., Burr, L., McGuckin, M. and Serisier, D. (2015). Collagen protease levels vary with airway microbiota composition and lung function in bronchiectasis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Gold Coast, Australia, 27 March – 1 April 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12495_14

Collagen protease levels vary with airway microbiota composition and lung function in bronchiectasis

2015

Conference Publication

Spatial variation in the composition of infective lung microbiota revealed by 16S rRNA gene sequence analysis of multisite bronchoalveolar lavage

Scoleri, G., Leong, L., Burr, L., Choo, J., Thomson, R., Serisier, D. and Rogers, G. (2015). Spatial variation in the composition of infective lung microbiota revealed by 16S rRNA gene sequence analysis of multisite bronchoalveolar lavage. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting 2015, Gold Coast, Australia, 27 March – 1 April 2015. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12494_8

Spatial variation in the composition of infective lung microbiota revealed by 16S rRNA gene sequence analysis of multisite bronchoalveolar lavage

2014

Journal Article

The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial

Rogers, Geraint B., Bruce, Kenneth D., Martin, Megan L., Burr, Lucy D. and Serisier, David J. (2014). The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial. The Lancet Respiratory Medicine, 2 (12), 988-996. doi: 10.1016/S2213-2600(14)70213-9

The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial

2014

Journal Article

A novel microbiota stratification system predicts future exacerbations in bronchiectasis

Rogers, Geraint B., Zain, Nur Masirah M., Bruce, Kenneth D., Burr, Lucy D., Chen, Alice C., Rivett, Damian W., McGuckin, Michael A. and Serisier, David J. (2014). A novel microbiota stratification system predicts future exacerbations in bronchiectasis. Annals of the American Thoracic Society, 11 (4), 496-503. doi: 10.1513/AnnalsATS.201310-335OC

A novel microbiota stratification system predicts future exacerbations in bronchiectasis