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2023 Conference Publication Gene expression of calcium signalling modulators in SARS-CoV-2 infectionAkison, Mia C., Eschke, Kathrin, Monteith, Gregory, Roberts-Thomson, Sarah, Labzin, Larisa and Robitaille, Mélanie (2023). Gene expression of calcium signalling modulators in SARS-CoV-2 infection. ASCEPT Annual Scientific, Sydney, NSW, Australia, 20-23 November 2023. |
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2023 Journal Article In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs® 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and Omicron BA.2Emanuel, Jackson, Papies, Jan, Galander, Celine, Adler, Julia M, Heinemann, Nicolas, Eschke, Kathrin, Merz, Sophie, Pischon, Hannah, Rose, Ruben, Krumbholz, Andi, Kulić, Žarko, Lehner, Martin D, Trimpert, Jakob and Müller, Marcel A (2023). In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs® 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and Omicron BA.2. Frontiers in Pharmacology, 14 1214351, 1-17. doi: 10.3389/fphar.2023.1214351 |
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2023 Journal Article Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion releaseLabzin, Larisa I., Chew, Keng Yih, Eschke, Kathrin, Wang, Xiaohui, Esposito, Tyron, Stocks, Claudia J., Rae, James, Patrick, Ralph, Mostafavi, Helen, Hill, Brittany, Yordanov, Teodor E., Holley, Caroline L., Emming, Stefan, Fritzlar, Svenja, Mordant, Francesca L., Steinfort, Daniel P., Subbarao, Kanta, Nefzger, Christian M., Lagendijk, Anne K., Gordon, Emma J., Parton, Robert G., Short, Kirsty R., Londrigan, Sarah L. and Schroder, Kate (2023). Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release. Science Signaling, 16 (782) eabq1366, eabq1366. doi: 10.1126/scisignal.abq1366 |
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2023 Journal Article Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by OmicronKreye, Jakob, Reincke, S. Momsen, Edelburg, Stefan, Jeworowski, Lara M., Kornau, Hans-Christian, Trimpert, Jakob, Hombach, Peter, Halbe, Sophia, Noelle, Volker, Meyer, Martin, Kattenbach, Stefanie, Sanchez-Sendin, Elisa, Schmidt, Marie L., Schwarz, Tatjana, Rose, Ruben, Krumbholz, Andi, Merz, Sophie, Adler, Julia M., Eschke, Kathrin, Abdelgawad, Azza, Schmitz, Dietmar, Sander, Leif E., Janssen, Uwe, Corman, Victor M. and Pruess, Harald (2023). Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by Omicron. iScience, 26 (4) 106323, 1-22. doi: 10.1016/j.isci.2023.106323 |
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2022 Journal Article The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variantsRothenberger, Sylvia, Hurdiss, Daniel L., Walser, Marcel, Malvezzi, Francesca, Mayor, Jennifer, Ryter, Sarah, Moreno, Hector, Liechti, Nicole, Bosshart, Andreas, Iss, Chloe, Calabro, Valerie, Cornelius, Andreas, Hospodarsch, Tanja, Neculcea, Alexandra, Looser, Thamar, Schlegel, Anja, Fontaine, Simon, Villemagne, Denis, Paladino, Maria, Schiegg, Dieter, Mangold, Susanne, Reichen, Christian, Radom, Filip, Kaufmann, Yvonne, Schaible, Doris, Schlegel, Iris, Zitt, Christof, Sigrist, Gabriel, Straumann, Marcel ... Trimpert, Jakob (2022). The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants. Nature Biotechnology, 40 (12), 1845-1854 . doi: 10.1038/s41587-022-01382-3 |
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2022 Journal Article Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replicationLos, Bruna, Preussner, Marco, Eschke, Kathrin, Vidal, Ricardo Martin, Abdelgawad, Azza, Olofsson, Didrik, Keiper, Sandra, Paulo-Pedro, Margarida, Grindel, Alica, Meinke, Stefan, Trimpert, Jakob and Heyd, Florian (2022). Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replication. Nucleic Acids Research, 50 (12), 6769-6785. doi: 10.1093/nar/gkac513 |
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2022 Journal Article Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomicsWyler, Emanuel, Adler, Julia M., Eschke, Kathrin, Teixeira Alves, G., Peidli, Stefan, Pott, Fabian, Kazmierski, Julia, Michalick, Laura, Kershaw, Olivia, Bushe, Judith, Andreotti, Sandro, Pennitz, Peter, Abdelgawad, Azza, Postmus, Dylan, Goffinet, Christine, Kreye, Jakob, Reincke, S. Momsen, Prüss, Harald, Blüthgen, Nils, Gruber, Achim D., Kuebler, Wolfgang M., Witzenrath, Martin, Landthaler, Markus, Nouailles, Geraldine and Trimpert, Jakob (2022). Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics. Molecular Therapy, 30 (5), 1952-1965. doi: 10.1016/j.ymthe.2022.03.014 |
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2022 Journal Article Rapid SARS-CoV-2 adaptation to available cellular proteasesChaudhry, M. Zeeshan, Eschke, Kathrin, Hoffmann, Markus, Grashoff, Martina, Abassi, Leila, Kim, Yeonsu, Brunotte, Linda, Ludwig, Stephan, Kröger, Andrea, Klawonn, Frank, Pöhlmann, Stefan H. and Cicin-Sain, Luka (2022). Rapid SARS-CoV-2 adaptation to available cellular proteases. Journal of Virology, 96 (5) e0218621, 1-17. doi: 10.1128/jvi.02186-21 |
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2022 Journal Article MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccinationKim, Yeonsu, Zheng, Xiaoyan, Eschke, Kathrin, Chaudhry, M. Zeeshan, Bertoglio, Federico, Tomić, Adriana, Krmpotić, Astrid, Hoffmann, Markus, Bar-On, Yotam, Boehme, Julia, Bruder, Dunja, Ebensen, Thomas, Brunotte, Linda, Ludwig, Stephan, Messerle, Martin, Guzman, Carlos, Mandelboim, Ofer, Hust, Michael, Pöhlmann, Stefan, Jonjić, Stipan and Čičin-Šain, Luka (2022). MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination. Cellular and Molecular Immunology, 19 (2), 234-244. doi: 10.1038/s41423-021-00814-5 |
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2021 Journal Article Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B.1.1.7 (Alpha) and B.1.351 (Beta)Trimpert, Jakob, Adler, Julia M, Eschke, Kathrin, Abdelgawad, Azza, Firsching, Theresa C, Ebert, Nadine, Thao, Tran Thi Nhu, Gruber, Achim D, Thiel, Volker, Osterrieder, Nikolaus and Kunec, Dusan (2021). Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B.1.1.7 (Alpha) and B.1.351 (Beta). Science Advances, 7 (49) eabk0172, eabk0172. doi: 10.1126/sciadv.abk0172 |
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2021 Journal Article Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studiesPommerenke, Claudia, Rand, Ulfert, Uphoff, Cord C., Nagel, Stefan, Zaborski, Margarete, Hauer, Vivien, Kaufmann, Maren, Meyer, Corinna, Denkmann, Sabine A., Riese, Peggy, Eschke, Kathrin, Kim, Yeonsu, Safranko, Zeljka Macak, Kurolt, Ivan-Christian, Markotic, Alemka, Cicin-Sain, Luka and Steenpass, Laura (2021). Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies. PloS one, 16 (8) e0255622, e0255622. doi: 10.1371/journal.pone.0255622 |
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2021 Journal Article A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutationsBertoglio, Federico, Fühner, Viola, Ruschig, Maximilian, Heine, Philip Alexander, Abassi, Leila, Klünemann, Thomas, Rand, Ulfert, Meier, Doris, Langreder, Nora, Steinke, Stephan, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Kuhn, Philipp, Riese, Peggy, Schäckermann, Dorina, Korn, Janin, Koch, Allan, Chaudhry, M Zeeshan, Eschke, Kathrin, Kim, Yeonsu, Zock-Emmenthal, Susanne, Becker, Marlies, Scholz, Margitta, Moreira, Gustavo Marçal Schmidt Garcia, Wenzel, Esther Veronika, Russo, Giulio, Garritsen, Hendrikus S P, Casu, Sebastian ... Hust, Michael (2021). A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations. Cell Reports, 36 (4) 109433, 1-23. doi: 10.1016/j.celrep.2021.109433 |
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2021 Journal Article Equine herpesvirus type 4 (EHV-4) outbreak in Germany: virological, serological, and molecular investigationsPavulraj, Selvaraj, Eschke, Kathrin, Theisen, Jana, Westhoff, Stephanie, Reimers, Gitta, Andreotti, Sandro, Osterrieder, Nikolaus and Azab, Walid (2021). Equine herpesvirus type 4 (EHV-4) outbreak in Germany: virological, serological, and molecular investigations. Pathogens, 10 (7), 810. doi: 10.3390/pathogens10070810 |
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2021 Journal Article SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interfaceBertoglio, Federico, Meier, Doris, Langreder, Nora, Steinke, Stephan, Rand, Ulfert, Simonelli, Luca, Heine, Philip Alexander, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Ruschig, Maximilian, Riese, Peggy, Eschke, Kathrin, Kim, Yeonsu, Schäckermann, Dorina, Pedotti, Mattia, Kuhn, Philipp, Zock-Emmenthal, Susanne, Wöhrle, Johannes, Kilb, Normann, Herz, Tobias, Becker, Marlies, Grasshoff, Martina, Wenzel, Esther Veronika, Russo, Giulio, Kröger, Andrea, Brunotte, Linda, Ludwig, Stephan, Fühner, Viola ... Hust, Michael (2021). SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface. Nature Communications, 12 (1) 1577. doi: 10.1038/s41467-021-21609-2 |
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2020 Journal Article Bearing the brunt: Mongolian khulan (Equus hemionus hemionus) are exposed to multiple influenza A strainsSoilemetzidou, Eirini S., de Bruin, Erwin, Eschke, Kathrin, Azab, Walid, Osterrieder, Nikolaus, Czirjak, Gabor A., Buuveibaatar, Bayarbaatar, Kaczensky, Petra, Koopmans, Marion, Walzer, Chris and Greenwood, Alex D. (2020). Bearing the brunt: Mongolian khulan (Equus hemionus hemionus) are exposed to multiple influenza A strains. Veterinary Microbiology, 242 108605. doi: 10.1016/j.vetmic.2020.108605 |
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2019 Journal Article A proofreading-impaired herpesvirus generates populations with quasispecies-like structureTrimpert, Jakob, Groenke, Nicole, Kunec, Dusan, Eschke, Kathrin, He, Shulin, McMahon, Dino P. and Osterrieder, Nikolaus (2019). A proofreading-impaired herpesvirus generates populations with quasispecies-like structure. Nature Microbiology, 4 (12), 2175-2183. doi: 10.1038/s41564-019-0547-x |
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2019 Journal Article A proofreading-impaired herpesvirus generates populations with quasispecies-like structure (vol 4, pg 2025, 2019)Trimpert, Jakob, Groenke, Nicole, Kunec, Dusan, Eschke, Kathrin, He, Shulin, McMahon, Dino P. and Osterrieder, Nikolaus (2019). A proofreading-impaired herpesvirus generates populations with quasispecies-like structure (vol 4, pg 2025, 2019). Nature Microbiology, 4 (11), 2025-2025. doi: 10.1038/s41564-019-0598-z |
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2019 Journal Article Fatal elephant endotheliotropic herpesvirus infection of two young Asian elephantsPavulraj, Selvaraj, Eschke, Kathrin, Prahl, Adriane, Flügger, Michael, Trimpert, Jakob, van den Doel, Petra B., Andreotti, Sandro, Kaessmeyer, Sabine, Osterrieder, Nikolaus and Azab, Walid (2019). Fatal elephant endotheliotropic herpesvirus infection of two young Asian elephants. Microorganisms, 7 (10), 396. doi: 10.3390/microorganisms7100396 |
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2019 Journal Article Detection of equid herpesviruses among different Arabian horse populations in EgyptAzab, Walid, Bedair, Sameh, Abdelgawad, Azza, Eschke, Kathrin, Farag, Gemelat K., Abdel-Raheim, Ali, Greenwood, Alex D., Osterrieder, Nikolaus and Ali, Ahmed A. H. (2019). Detection of equid herpesviruses among different Arabian horse populations in Egypt. Veterinary Medicine and Science, 5 (3), 361-371. doi: 10.1002/vms3.176 |
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2018 Journal Article Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimizationEschke, Kathrin, Trimpert, Jakob, Osterrieder, Nikolaus and Kunec, Dusan (2018). Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization. PLoS Pathogens, 14 (1), e1006857. doi: 10.1371/journal.ppat.1006857 |
