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2018 Journal Article An ovine model of hyperdynamic endotoxemia and vital organ metabolismByrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904 |
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2017 Journal Article Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapyAdiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Fraser, John F, Smith, Maree T and Ghassabian, Sussan (2017). Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy. Drug metabolism reviews, 50 (2), 1-16. doi: 10.1080/03602532.2017.1417423 |
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2017 Journal Article Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenationSinnah, Fabrice, Shekar, Kiran, Abdul-Aziz, Mohd H, Buscher, Hergen, Diab, Sara D., Fisquet, Stephanie, Fung, Yoke L., McDonald, Charles I., Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John F., Roberts, Jason A. and ASAP ECMO investigators (2017). Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation. Critical Care and Resuscitation, 19 (Suppl 1), 8-14. |
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2017 Journal Article Appraising extracorporeal life support — current and future roles in adult intensive careShekar, Kiran, Brodie, Daniel, Fraser, John and MacLaren, Graeme (2017). Appraising extracorporeal life support — current and future roles in adult intensive care. Critical Care and Resuscitation, 19, 5-7. |
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2017 Journal Article Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation supportPassmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Diab, Sara D., Dunster, Kimble R., Spanevello, Michelle M., McDonald, Charles I., Tung, John-Paul, Pecheniuk, Natalie M., Hay, Karen, Shekar, Kiran and Fraser, John F. (2017). Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation support. Critical Care, 21 (1) 191, 1-9. doi: 10.1186/s13054-017-1788-9 |
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2017 Journal Article Successful provision of inter-hospital extracorporeal cardiopulmonary resuscitation for acute post-partum pulmonary embolismMcDonald, C., Laurie, J., Janssens, S., Zazulak, C., Kotze, P. and Shekar, K. (2017). Successful provision of inter-hospital extracorporeal cardiopulmonary resuscitation for acute post-partum pulmonary embolism. International Journal of Obstetric Anesthesia, 30, 65-68. doi: 10.1016/j.ijoa.2017.01.003 |
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2017 Journal Article The effects of the introduction of an adult ECMO program on statewide referral patterns, casemix and outcomes in patients with acute respiratory distress syndrome or pneumoniaMullany, Dan, Shekar, Kiran, Ziegenfuss, Marc, Joyce, Christopher, Pilcher, David, Dobson, Annette and Fraser, John F. (2017). The effects of the introduction of an adult ECMO program on statewide referral patterns, casemix and outcomes in patients with acute respiratory distress syndrome or pneumonia. Intensive Care Medicine, 43 (7), 1065-1066. doi: 10.1007/s00134-017-4771-7 |
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2016 Journal Article Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation supportPassmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Dunster, Kimble R., Diab, Sara D., Tung, John-Paul, Minchinton, Robyn M., McDonald, Charles I., Anstey, Chris M., Shekar, Kiran and Fraser, John F. (2016). Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support. AJP - Lung Cellular and Molecular Physiology, 311 (6), L1202-L1212. doi: 10.1152/ajplung.00296.2016 |
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2016 Journal Article Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuitPlatts, David G., McDonald, Charles, Shekar, Kiran, Burstow, Darryl J., Mullany, Daniel, Ziegenfuss, Marc, Diab, Sara and Fraser, John F. (2016). Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuit. Intensive Care Medicine Experimental, 4 (1) 7, 7. doi: 10.1186/s40635-016-0079-0 |
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2016 Journal Article High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentationMoosavi, Seyed Mojtaba, Shekar, Kiran, Fraser, John, Smith, Maree T. and Ghassabian, Sussan (2016). High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation. Journal of Chromatography B, 1038, 80-87. doi: 10.1016/j.jchromb.2016.10.038 |
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2016 Journal Article Association between post-sternotomy tracheostomy and deep sternal wound infection: a retrospective analysisTsai, Yi-Chin, Phan, Kevin, Stroebel, Andrie, Williams, Livia, Nicotra, Lisa, Drake, Lesley, Ryan, Elizabeth, McGree, James, Tesar, Peter and Shekar, Kiran (2016). Association between post-sternotomy tracheostomy and deep sternal wound infection: a retrospective analysis. Journal of Thoracic Disease, 8 (11), 3294-3300. doi: 10.21037/jtd.2016.11.70 |
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2016 Journal Article Low preoperative selenium is associated with post-operative atrial fibrillation in patients having intermediate-risk coronary artery surgeryMcDonald, C., Fraser, J., Shekar, K., Clarke, A., Coombes, J., Barnett, A., Pearse, B. and Fung, L. (2016). Low preoperative selenium is associated with post-operative atrial fibrillation in patients having intermediate-risk coronary artery surgery. European Journal of Clinical Nutrition, 70 (10), 1138-1143. doi: 10.1038/ejcn.2016.125 |
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2016 Journal Article Mechanical circulatory support in the new era: an overviewShekar, Kiran, Gregory, Shaun D. and Fraser, John F. (2016). Mechanical circulatory support in the new era: an overview. Critical Care, 20 (1) 66, 66.1-66.12. doi: 10.1186/s13054-016-1235-3 |
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2016 Journal Article Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic reviewObonyo, Nchafatso G., Fanning, Jonathon P., Ng, Angela S. Y., Pimenta, Leticia P., Shekar, Kiran, Platts, David G., Maitland, Kathryn and Fraser, John F. (2016). Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review. Intensive Care Medicine Experimental, 4 (1) 38, 1-16. doi: 10.1186/s40635-016-0112-3 |
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2016 Journal Article The complex relationship of extracorporeal membrane oxygenation and acute kidney injury: causation or association?Kilburn, Daniel J., Shekar, Kiran and Fraser, John F. (2016). The complex relationship of extracorporeal membrane oxygenation and acute kidney injury: causation or association?. BioMed Research International, 2016 1094296, 1094296-14. doi: 10.1155/2016/1094296 |
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2015 Journal Article Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine modelsShekar, Kiran, Roberts, Jason A., Barnett, Adrian G., Diab, Sara, Wallis, Steven C., Fung, Yoke L. and Fraser, John F. (2015). Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models. Critical Care, 19 (1) 437, 1-11. doi: 10.1186/s13054-015-1151-y |
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2015 Journal Article Ovine platelet function is unaffected by extracorporeal membrane oxygenation within the first 24 hHayes, Rylan A., Foley, Samuel, Shekar, Kiran, Diab, Sara, Dunster, Kimble R., McDonald, Charles and Fraser, John F. (2015). Ovine platelet function is unaffected by extracorporeal membrane oxygenation within the first 24 h. Blood Coagulation and Fibrinolysis, 26 (7), 816-822. doi: 10.1097/MBC.0000000000000360 |
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2015 Journal Article Successful conservative management of an iatrogenic ECMO cannula--related inferior vena cava injuryBhaskar, B., Mullany, D., Parmar, D., Ziengenfuss, M. and Shekar, K. (2015). Successful conservative management of an iatrogenic ECMO cannula--related inferior vena cava injury. Anaesthesia and Intensive Care, 43 (3), 418-419. |
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2015 Journal Article Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo studyShekar, Kiran, Roberts, Jason A, Mcdonald, Charles I, Ghassabian, Sussan, Anstey, Chris, Wallis, Steven C, Mullany, Daniel V, Fung, Yoke L and Fraser, John F (2015). Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study. Critical Care, 19 (164) 164, 164. doi: 10.1186/s13054-015-0891-z |
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2015 Journal Article The impact of acute lung injury, ECMO and transfusion on oxidative stress and plasma selenium levels in an ovine modelMcDonald, Charles I, Fung, Yoke Lin, Shekar, Kiran, Diab, Sara D, Dunster, Kimble R, Passmore, Margaret R, Foley, Samuel R, Simonova, Gabriela, Platts, David and Fraser, John F (2015). The impact of acute lung injury, ECMO and transfusion on oxidative stress and plasma selenium levels in an ovine model. Journal of Trace Elements in Medicine and Biology, 30, 4-10. doi: 10.1016/j.jtemb.2015.01.004 |
