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2014 Conference Publication Evidence of ECMO induced changes to haemostasis in an ovine modelFoley, S., Fung, L., Simonova, G., Solano, C., Diab, S., Dunster, K., McDonald, C., Shekar, K. and Fraser, J. (2014). Evidence of ECMO induced changes to haemostasis in an ovine model. 38th Australian and New Zealand Scientific Meeting on Intensive Care and the 19th Annual Paediatric and Neonatal intensive Care Conference, Hobart, Australia, October, 2013. Philadelphia, United States: Elsevier. doi: 10.1016/j.aucc.2013.10.057 |
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2013 Journal Article Can optimal drug dosing during ECMO improve outcomes?Shekar, Kiran, Fraser, John F. and Roberts, Jason A. (2013). Can optimal drug dosing during ECMO improve outcomes?. Intensive Care Medicine, 39 (12), 2237-2237. doi: 10.1007/s00134-013-3080-z |
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2013 Journal Article To ventilate, oscillate, or cannulate?Shekar, Kiran, Davies, Andrew R., Mullany, Daniel V., Tiruvoipati, Ravindranath and Fraser, John F. (2013). To ventilate, oscillate, or cannulate?. Journal of Critical Care, 28 (5), 655-662. doi: 10.1016/j.jcrc.2013.04.009 |
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2013 Journal Article Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhageFung, Y. L., Tung, J. P., Foley, S. R., Simonova, G., Thom, O., Staib, A., Collier, J., Dunster, K. R., Solano, C., Shekar, K., Chew, M. S. and Fraser, J. F. (2013). Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage. Vox Sanguinis, 105 (2), 150-158. doi: 10.1111/vox.12032 |
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2013 Journal Article Depletion of myocardial glucose is observed during endotoxaemic but not haemorrhagic shock in a porcine modelChew M. S., Shekar K., Brand B. A., Norin C. and Barnett A. G. (2013). Depletion of myocardial glucose is observed during endotoxaemic but not haemorrhagic shock in a porcine model. Critical Care, 17 (4) R164. doi: 10.1186/cc12843 |
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2013 Journal Article Is hyperoxaemia helping or hurting patients during extracorporeal membrane oxygenation? Review of a complex problemHayes, R. A., Shekar, K. and Fraser, J. F. (2013). Is hyperoxaemia helping or hurting patients during extracorporeal membrane oxygenation? Review of a complex problem. Perfusion, 28 (3), 184-193. doi: 10.1177/0267659112473172 |
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2013 Journal Article The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenationShekar, Kiran, Roberts, Jason A., Smith, Maree T., Fung, Yoke L. and Fraser, John F. (2013). The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation. BMC Anesthesiology, 13 (1) 7, 7.1-7.10. doi: 10.1186/1471-2253-13-7 |
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2013 Journal Article Single-centre experience of donation after cardiac deathKumar, Raj, Shekar, Kiran and Fraser, John F. (2013). Single-centre experience of donation after cardiac death. Medical Journal of Australia, 198 (2), 87-88. doi: 10.5694/mja12.11502 |
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2013 Journal Article Hyperoxic damage and the need for optimised oxygenation practicesHayes, Rylan A., Shekar, Kiran and Fraser, John F. (2013). Hyperoxic damage and the need for optimised oxygenation practices. Critical Care, 17 (4) 441, 441. doi: 10.1186/cc12802 |
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2013 Conference Publication The impact of continuous flow from venovenous extracorporeal membrane oxygenation cannulae on tricuspid valve geometry and functionPlatts, D., Diab, S., MacDonald, M., Chemonges, S., Dunster, K., Shekar, K., Burstow, D., Mullany, D. and Fraser, D. (2013). The impact of continuous flow from venovenous extracorporeal membrane oxygenation cannulae on tricuspid valve geometry and function. 2013 ANZSCTS Annual Scientific Meeting, Darwin, NT Australia, 22 - 25 August 2013. Chatswood, NSW Australia: Elsevier Australia. doi: 10.1016/j.hlc.2013.05.474 |
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2013 Conference Publication Feasibility of a novel echocardiographic imaging technique, intracatheter echocardiography, to guide venovenous extracorporeal membrane oxygenation cannulae placement in a validated ovine modelPlatts, D., Hilton, A., Diab, S., MacDonald, C., Tunbridge, M., Chemonges, S., Dunster, K., Shekar, K., Burstow, D. and Fraser, J. (2013). Feasibility of a novel echocardiographic imaging technique, intracatheter echocardiography, to guide venovenous extracorporeal membrane oxygenation cannulae placement in a validated ovine model. CSANZ 2013: 61st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand; in conjunction with the 37th Annual Scientific Meeting of the International Society for Heart Research, Gold Coast, QLD, Australia, 8-11 August, 2013. Chatswood, NSW, Australia: Elsevier Australia. doi: 10.1016/j.hlc.2013.05.429 |
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2012 Journal Article Drotrecogin alfa (activated) falls amid continuing enthusiasm to normalise physiology in ICU patientsShekar, Kiran and Fraser, John F. (2012). Drotrecogin alfa (activated) falls amid continuing enthusiasm to normalise physiology in ICU patients. Critical Care and Resuscitation, 14 (4), 324-324. doi: 10.1016/s1441-2772(23)01775-1 |
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2012 Journal Article Massive bilateral pulmonary emboli, paradoxical embolus and the knot of lifePlatts, David, Shekar, Kiran, Senz, Ainslie and Thomson, Bruce (2012). Massive bilateral pulmonary emboli, paradoxical embolus and the knot of life. European Heart Journal, 33 (24), 3077-3077. doi: 10.1093/eurheart/ehs256 |
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2012 Journal Article ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMOShekar, Kiran, Roberts, Jason A., Welsh, Susan, Buscher, Hergen, Rudham, Sam, Burrows, Fay, Ghassabian, Sussan, Wallis, Steven C., Levkovich, Bianca, Pellegrino, Vin, McGuiness, Shay, Parke, Rachael, Gilder, Eileen, Barnett, Adrian G., Walsham, James, Mullany, Daniel V., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO. BMC Anesthesiology, 12 (1) 29, 29.1-29.9. doi: 10.1186/1471-2253-12-29 |
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2012 Journal Article Sedation during extracorporeal membrane oxygenation-why more is lessShekar, K., Roberts, J. A., Ghassabian, S., Mullany, D. V., Ziegenfuss, M., Smith, M. T., Fung, Y. L. and Fraser, J. F. (2012). Sedation during extracorporeal membrane oxygenation-why more is less. Anaesthesia and Intensive Care, 40 (6), 1067-1069. |
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2012 Journal Article Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?Shekar, Kiran, Roberts, Jason A., Ghassabian, Sussan, Mullany, Daniel V., Wallis, Steven C., Smith, Maree T. and Fraser, John F. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?. Journal of Antimicrobial Chemotherapy, 68 (3), 726-727. doi: 10.1093/jac/dks435 |
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2012 Journal Article Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenationShekar, Kiran, Roberts, Jason A., McDonald, Charles I., Fisquet, Stephanie, Barnett, Adrian G., Mullany, Daniel V., Ghassabian, Sussan, Wallis, Steven C., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation. Critical Care, 16 (5) R194, R194.1-R194.7. doi: 10.1186/cc11679 |
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2012 Journal Article High-throughput assay for simultaneous quantification of the plasma concentrations of morphine, fentanyl, midazolam and their major metabolites using automated SPE coupled to LC-MS/MSGhassabian, Sussan, Moosavi, Seyed Mojtaba, Valero, Yarmarly Guerra, Shekar, Kiran, Fraser, John F. and Smith, Maree T. (2012). High-throughput assay for simultaneous quantification of the plasma concentrations of morphine, fentanyl, midazolam and their major metabolites using automated SPE coupled to LC-MS/MS. Journal of Chromatography B, 903, 126-133. doi: 10.1016/j.jchromb.2012.07.005 |
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2012 Journal Article Outcomes of the first 30 cases of an adult extracorporeal membrane oxygenation program: strategies to manage the "learning curve" and implications for intensive care unit risk adjustment modelsMullany, Daniel V., Bull, Taressa N., Hunt, William, Shekar, Kiran, Thomson, Bruce, Fraser, John F. and Ziegenfuss, Marc (2012). Outcomes of the first 30 cases of an adult extracorporeal membrane oxygenation program: strategies to manage the "learning curve" and implications for intensive care unit risk adjustment models. Critical Care and Resuscitation, 14 (2), 119-29. |
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2012 Journal Article Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactionsShekar, Kiran, Fung, Yoke L., Diab, Sara, Mullany, Daniel V., McDonald, Charles I., Dunster, Kimble R., Fisquet, Stephanie, Platts, David G., Stewart, David, Wallis, Steven C., Smith, Maree T., Roberts, Jason A. and Fraser, John F. (2012). Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions. Critical Care and Resuscitation, 14 (2), 105-111. |