2019 Journal Article Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? NoShekar, Kiran and Brodie, Daniel (2019). Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? No. Critical Care Medicine, 47 (8), 1147-1149. doi: 10.1097/CCM.0000000000003865 |
2019 Journal Article ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sandSchmidt, Matthieu, Combes, Alain and Shekar, Kiran (2019). ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sand. Intensive Care Medicine, 45 (8), 1140-1142. doi: 10.1007/s00134-019-05632-y |
2019 Journal Article Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndromeShekar, Kiran and Schmidt, Matthieu (2019). Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine, 200 (2), 265-266. doi: 10.1164/rccm.201903-0594LE |
2019 Journal Article Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?Shekar, Kiran, Abrams, Darryl and Schmidt, Matthieu (2019). Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?. Journal of Thoracic Disease, 11 (7), 2656-2659. doi: 10.21037/jtd.2019.05.58 |
2019 Journal Article Steps to enhance safety of tracheostomy on ECMOGrewal, Jatinder, Sutt, Anna-Liisa, Shekar, Kiran and Fraser, John F. (2019). Steps to enhance safety of tracheostomy on ECMO. Journal of Intensive Care Medicine, 2019, 088506661985107-2. doi: 10.1177/0885066619851074 |
2019 Journal Article Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise PharmacotherapyAdiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Tesar, Peter, Naidoo, Rishendran, Rapchuk, Ivan, Belz, Stephen, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2019). Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy. Methods and Protocols, 2 (2) 38, 38-12. doi: 10.3390/mps2020038 |
2019 Journal Article Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane OxygenationShekar, Kiran, Grewal, Jatinder, Sutt, Anna Lisa and Fraser, John (2019). Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation. ASAIO journal (American Society for Artificial Internal Organs : 1992), 65 (4), e44-e45. doi: 10.1097/MAT.0000000000000969 |
2019 Journal Article Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shockPassmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015 |
2019 Journal Article Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experienceGrewal, Jatinder, Sutt, Anna-Liisa, Cornmell, George, Shekar, Kiran and Fraser, John (2019). Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience. Journal of Intensive Care Medicine, 35 (11), 1153-1161. doi: 10.1177/0885066619837939 |
2019 Journal Article Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patientsCheng, Vesa, Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2019). Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients. Expert Opinion on Drug Metabolism & Toxicology, 15 (2), 103-112. doi: 10.1080/17425255.2019.1563596 |
2019 Journal Article Pre-clinical study protocol: Blood transfusion in endotoxaemic shockObonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005 |
2018 Journal Article Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shockPassmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4 |
2018 Conference Publication Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock ResuscitationFanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation. American Heart Association's 2018 Scientific Sessions, Chicago, IL United States, 10-12 November 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/circ.138.suppl_1.17116 |
2018 Journal Article Oscillating between prone ventilation and ECMO?Lavana, Jayshree and Shekar, Kiran (2018). Oscillating between prone ventilation and ECMO?. Journal of Thoracic Disease, 10 (S33), S4144-S4146. doi: 10.21037/jtd.2018.10.71 |
2018 Journal Article Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the futureBoyle, Andrew J., Sklar, Michael C., McNamee, James J., Brodie, Daniel, Slutsky, Arthur S., Brochard, Laurent, McAuley, Daniel F., International ECMO Network (ECMONet) and Shekar, Kiran (2018). Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future. The Lancet. Respiratory medicine, 6 (11), 874-884. doi: 10.1016/S2213-2600(18)30326-6 |
2018 Journal Article Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemiaByrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC |
2018 Journal Article An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activitySreevatsav Adiraju, Santosh Kumar, Shekar, Kiran, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2018). An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activity. Bioanalysis, 10 (19), 1577-1590. doi: 10.4155/bio-2018-0102 |
2018 Journal Article A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenationJoyce, Christopher John, Shekar, Kiran and Cook, David Andrew (2018). A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation. Intensive Care Medicine Experimental, 6 (1) 25, 25. doi: 10.1186/s40635-018-0183-4 |
2018 Conference Publication Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shockObonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, A.C., See Hoe, L., Pedersen, S., Fauzi, M., Pimenta, L., Van Haren, F., Shekar, K., Anstey, C., Tung, J.P., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock. 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies (WFPICCS 2018), Singapore, 9-13 June 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000538016.15507.8c |
2018 Journal Article Patient selection for VV ECMO: have we found the crystal ball?Ahuja, Abhilasha and Shekar, Kiran (2018). Patient selection for VV ECMO: have we found the crystal ball?. Journal of Thoracic Disease, 10 (Suppl 17), S1979-S1981. doi: 10.21037/jtd.2018.05.83 |