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2025

Journal Article

A synthetic cyclic peptide for promoting antigen presentation and immune activation

Zhang, Jiahui, Madge, Harrison Y. R., Mahmoud, Asmaa, Lu, Lantian, Wang, Wanyi, Huang, Wenbin, Koirala, Prashamsa, Gonzalez Cruz, Jazmina L., Kong, Wei Yang, Bashiri, Sahra, Shalash, Ahmed O., Hussein, Waleed M., Khalil, Zeinab G., Wells, James W., Toth, Istvan and Stephenson, Rachel J. (2025). A synthetic cyclic peptide for promoting antigen presentation and immune activation. NPJ Vaccines, 10 (1) 9, 9-1. doi: 10.1038/s41541-024-01050-4

A synthetic cyclic peptide for promoting antigen presentation and immune activation

2024

Book Chapter

Recent trends in peptide drug discovery and development

Madge, H. Y. R. and Muttenthaler, M. (2024). Recent trends in peptide drug discovery and development. Sustainability in tides chemistry. (pp. 23-49) edited by Alessandra Tolomelli, Lucia Ferrazzano and Walter Cabri. London, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781837674541-00023

Recent trends in peptide drug discovery and development

2024

Conference Publication

Synthetic anti-cocaine nano-vaccine successfully prevents cocaine-induced hyperlocomotion

Madge, Harrison, Alexander, Suzy, Azuar, Armira, Zhang, Jiahui, Koirala, Prashamsa, Burne, Thomas, Toth, Istvan and Stephenson, Rachel (2024). Synthetic anti-cocaine nano-vaccine successfully prevents cocaine-induced hyperlocomotion. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons.

Synthetic anti-cocaine nano-vaccine successfully prevents cocaine-induced hyperlocomotion

2024

Journal Article

Cyclic Peptide Conjugate Vaccines and Physically Mixed Cyclic Peptide Vaccines for Subcutaneous Immunization

Huang, Wenbin, Madge, Harrison Y. R., Toth, Istvan and Stephenson, Rachel J. (2024). Cyclic Peptide Conjugate Vaccines and Physically Mixed Cyclic Peptide Vaccines for Subcutaneous Immunization. Methods in Molecular Biology, 2821, 111-127. doi: 10.1007/978-1-0716-3914-6_9

Cyclic Peptide Conjugate Vaccines and Physically Mixed Cyclic Peptide Vaccines for Subcutaneous Immunization

2023

Journal Article

Synthetic anti-cocaine nanoaccine successfully prevents cocaine-induced hyperlocomotion

Madge, Harrison Y. R., Alexander, Suzy, Azuar, Armira, Zhang, Jiahui, Koirala, Prashamsa, Burne, Thomas H., Toth, Istvan and Stephenson, Rachel J. (2023). Synthetic anti-cocaine nanoaccine successfully prevents cocaine-induced hyperlocomotion. Journal of Medicinal Chemistry, 66 (17), 12407-12419. doi: 10.1021/acs.jmedchem.3c00889

Synthetic anti-cocaine nanoaccine successfully prevents cocaine-induced hyperlocomotion

2022

Other Outputs

Development of vaccine delivery systems for peptide antigens and small molecule haptens

Madge, Harrison (2022). Development of vaccine delivery systems for peptide antigens and small molecule haptens. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/9869022

Development of vaccine delivery systems for peptide antigens and small molecule haptens

2022

Journal Article

Poly(hydrophobic amino acids) and liposomes for delivery of vaccine against Group A Streptococcus

Azuar, Armira, Madge, Harrison Y. R., Boer, Jennifer C., Gonzalez Cruz, Jazmina L., Wang, Jingwen, Khalil, Zeinab G., Deceneux, Cyril, Goodchild, Georgia, Yang, Jieru, Koirala, Prashamsa, Hussein, Waleed M., Capon, Robert J., Plebanski, Magdalena, Toth, Istvan and Skwarczynski, Mariusz (2022). Poly(hydrophobic amino acids) and liposomes for delivery of vaccine against Group A Streptococcus. Vaccines, 10 (8) 1212, 1-14. doi: 10.3390/vaccines10081212

Poly(hydrophobic amino acids) and liposomes for delivery of vaccine against Group A Streptococcus

2022

Journal Article

Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Hussein, Waleed M., Chappell, Keith J., Watterson, Daniel, Young, Paul R., Skwarczynski, Mariusz and Toth, Istvan (2022). Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems. Pharmaceutics, 14 (4) 856, 856. doi: 10.3390/pharmaceutics14040856

Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems

2022

Journal Article

Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines

Huang, Wenbin, Madge, Harrison Y. R., Zhang, Jiahui, Gilmartin, Lachlan, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines. International Journal of Pharmaceutics, 617 121614, 1-12. doi: 10.1016/j.ijpharm.2022.121614

Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines

2022

Journal Article

Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus

Madge, Harrison Y. R., Huang, Wenbin, Gilmartin, Lachlan, Rigau-Planella, Berta, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Santiago, Viviene S., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus. Biomaterials Science, 10 (1), 281-293. doi: 10.1039/d1bm01333e

Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus

2021

Journal Article

Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., Toth, Istvan and Skwarczynski, Mariusz (2021). Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay. Vaccines, 9 (12) 1493, 1-21. doi: 10.3390/vaccines9121493

Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay

2021

Other Outputs

Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander, Watterson, Daniel, Young, Paul R., Toth, Istvan and Skwarczynski, Mariusz (2021). Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay. doi: 10.21203/rs.3.pex-1559/v1

Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay

2021

Book Chapter

Nanocarrier-based vaccine delivery systems for synthetic peptide vaccines

Madge, Harrison Y.R., Stephenson, Rachel J. and Toth, Istvan (2021). Nanocarrier-based vaccine delivery systems for synthetic peptide vaccines. Handbook of nanotechnology applications: environment, energy, agriculture and medicine. (pp. 509-535) edited by Woei Jye Lau, Kajornsak Faungnawakij, Kuakoon Piyachomkwan and Uracha Rungsardthong Ruktanonchai. Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-821506-7.00020-x

Nanocarrier-based vaccine delivery systems for synthetic peptide vaccines

2020

Journal Article

Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens

Madge, Harrison Y. R., Sharma, Hansa, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert John, Toth, Istvan and Stephenson, Rachel (2020). Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens. Journal of Medicinal Chemistry, 63 (10) acs.jmedchem.0c00203, 5387-5397. doi: 10.1021/acs.jmedchem.0c00203

Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens