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2018

Journal Article

Dendrimer heparan sulfate glycomimetics: potent heparanase inhibitors for anticancer therapy

Zubkova, Olga V., Ahmed, Yassir A., Guimond, Scott E., Noble, Sophia-Louise, Miller, John Holmes, Smith, Raymond Alexander Alfred, Nurcombe, Victor, Tyler, Peter C., Weissmann, Marina, Vlodavsky, Israel and Turnbull, Jeremy E. (2018). Dendrimer heparan sulfate glycomimetics: potent heparanase inhibitors for anticancer therapy. ACS Chemical Biology, 13 (12), 3236-3242. doi: 10.1021/acschembio.8b00909

Dendrimer heparan sulfate glycomimetics: potent heparanase inhibitors for anticancer therapy

2018

Journal Article

Improved recovery from limb ischaemia by delivery of an affinity-isolated heparan sulphate

Poon, Selina, Lu, Xiaohua, Smith, Raymond A. A., Ho, Pei, Bhakoo, Kishore, Nurcombe, Victor and Cool, Simon M. (2018). Improved recovery from limb ischaemia by delivery of an affinity-isolated heparan sulphate. Angiogenesis, 21 (4), 777-791. doi: 10.1007/s10456-018-9622-9

Improved recovery from limb ischaemia by delivery of an affinity-isolated heparan sulphate

2018

Journal Article

Retention of the structure and function of heparan sulfate biomaterials after gamma irradiation

Smith, Raymond A. A., Chua, R. J. E., Carnachan, Susan M., Tan, Clarissa L. L., Sims, Ian M., Hinkley, Simon F. R., Nurcombe, Victor and Cool, Simon M. (2018). Retention of the structure and function of heparan sulfate biomaterials after gamma irradiation. Tissue Engineering - Part A, 24 (9-10), 729-739. doi: 10.1089/ten.tea.2017.0263

Retention of the structure and function of heparan sulfate biomaterials after gamma irradiation

2018

Conference Publication

Harnessing glycocalyx interactions to modulate differentiation and development

Huang, Mia L., Michalak, Austen L., Tota, Ember M., Smith, Raymond Alexander, Trieger, Greg W. and Godula, Kamil (2018). Harnessing glycocalyx interactions to modulate differentiation and development. Experimental Biology 2018 Meeting, San Diego, CA United States, 21-25 April 2018. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.2018.32.1_supplement.673.16

Harnessing glycocalyx interactions to modulate differentiation and development

2018

Journal Article

Small molecule antagonist of cell surface glycosaminoglycans restricts mouse embryonic stem cells in a pluripotent state

Huang, Mia L., Michalak, Austen L., Fisher, Christopher J., Christy, Mitchell, Smith, Raymond A. A. and Godula, Kamil (2018). Small molecule antagonist of cell surface glycosaminoglycans restricts mouse embryonic stem cells in a pluripotent state. Stem Cells, 36 (1), 45-54. doi: 10.1002/stem.2714

Small molecule antagonist of cell surface glycosaminoglycans restricts mouse embryonic stem cells in a pluripotent state

2017

Journal Article

Growth differentiation factor 5-mediated enhancement of chondrocyte phenotype is inhibited by heparin: implications for the use of heparin in the clinic and in tissue engineering applications

Ayerst, Bethanie I., Smith, Raymond A.A., Nurcombe, Victor, Day, Anthony J., Merry, Catherine L.R. and Cool, Simon M. (2017). Growth differentiation factor 5-mediated enhancement of chondrocyte phenotype is inhibited by heparin: implications for the use of heparin in the clinic and in tissue engineering applications. Tissue Engineering - Part A, 23 (7-8), 275-292. doi: 10.1089/ten.tea.2016.0364

Growth differentiation factor 5-mediated enhancement of chondrocyte phenotype is inhibited by heparin: implications for the use of heparin in the clinic and in tissue engineering applications

2016

Journal Article

Determining the extent of heparan sulfate depolymerisation following heparin lyase treatment

Carnachan, Susan M., Bell, Tracey J., Sims, Ian M., Smith, Raymond A.A., Nurcombe, Victor, Cool, Simon M. and Hinkley, Simon F.R. (2016). Determining the extent of heparan sulfate depolymerisation following heparin lyase treatment. Carbohydrate Polymers, 152, 592-597. doi: 10.1016/j.carbpol.2016.07.024

Determining the extent of heparan sulfate depolymerisation following heparin lyase treatment

2016

Conference Publication

Glycocalyx based strategies to modulate embryonic stem cell fates

Huang, Mia, Godula, Kamil, Smith, Raymond, Christy, Mitchell, Fisher, Christopher and Michalak, Austen (2016). Glycocalyx based strategies to modulate embryonic stem cell fates. ACS Spring 2016 Meeting, San Diego, CA United States, 13 - 17 March 2016. Washington, DC United States: American Chemical Society.

Glycocalyx based strategies to modulate embryonic stem cell fates

2016

Book Chapter

Glycocalyx remodeling with glycopolymer-based proteoglycan mimetics

Huang, Mia L., Smith, Raymond A. A., Trieger, Greg W. and Godula, Kamil (2016). Glycocalyx remodeling with glycopolymer-based proteoglycan mimetics. Macro-glycoligands: methods and protocols. (pp. 207-224) edited by Xue-Long Sun. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-3130-9_17

Glycocalyx remodeling with glycopolymer-based proteoglycan mimetics

2015

Journal Article

Structural determinants of heparin-transforming growth factor-β1 interactions and their effects on signaling

Lee, Jonathan, Wee, Sheena, Gunaratne, Jayantha, Chua, R. J. E., Smith, Raymond A. A., Ling, Ling, Fernig, David G., Swaminathan, Kunchithapadam, Nurcombe, Victor and Cool, Simon M. (2015). Structural determinants of heparin-transforming growth factor-β1 interactions and their effects on signaling. Glycobiology, 25 (12), 1491-1504. doi: 10.1093/glycob/cwv064

Structural determinants of heparin-transforming growth factor-β1 interactions and their effects on signaling

2015

Journal Article

Use of flow cytometry for characterization and fractionation of cell populations based on their expression of heparan sulfate epitopes

Holley, Rebecca J., Smith, Raymond A., van de Westerlo, Els M. A., Pickford, Claire E., Merry, C. L. R. and van Kuppevelt, Toin H. (2015). Use of flow cytometry for characterization and fractionation of cell populations based on their expression of heparan sulfate epitopes. Glycosaminoglycans: Chemistry and Biology, 1229, 239-251. doi: 10.1007/978-1-4939-1714-3_21

Use of flow cytometry for characterization and fractionation of cell populations based on their expression of heparan sulfate epitopes

2014

Conference Publication

Glycocalyx remodeling with synthetic proteoglycan mimetics promotes neural specification in embryonic stem cells

Godula, Kamil, Huang, Mia, Smith, Raymond and Trieger, Greg (2014). Glycocalyx remodeling with synthetic proteoglycan mimetics promotes neural specification in embryonic stem cells. Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, HI, United States, 16-19 November 2014. Cary, NC, United States: Oxford University Press.

Glycocalyx remodeling with synthetic proteoglycan mimetics promotes neural specification in embryonic stem cells

2011

Journal Article

Glycosaminoglycans as regulators of stem cell differentiation

Smith, Raymond A. A., Meade, Kate, Pickford, Claire E., Holley, Rebecca J. and Merry, Catherine L. R. (2011). Glycosaminoglycans as regulators of stem cell differentiation. Biochemical Society Transactions, 39 (1), 383-387. doi: 10.1042/bst0390383

Glycosaminoglycans as regulators of stem cell differentiation