|
2004 Journal Article Virtual drug discovery using graphAdams, P., Bryant, D. E., Long, S., Smythe, M. L. and Tran, T. T. (2004). Virtual drug discovery using graph. Bulletin of the Institute of Combinatorics and its Applications, 40, 100-106. |
|
2004 Journal Article Increased site 1 affinity improves biopotency of porcine growth hormone - Evidence against diffusion dependent receptor dimerizationWan, Y., McDevitt, A., Shen, B. J., Smythe, M. L. and Waters, M. J. (2004). Increased site 1 affinity improves biopotency of porcine growth hormone - Evidence against diffusion dependent receptor dimerization. Journal of Biological Chemistry, 279 (43), 44775-44784. doi: 10.1074/jbc.M406092200 |
|
2004 Journal Article Development of small molecules that mimic the binding of w-conotoxins at the N-type voltage-gated calcium channelSchroeder, I.C., Smythe, M. L. and Lewis, R. J. (2004). Development of small molecules that mimic the binding of w-conotoxins at the N-type voltage-gated calcium channel. Molecular Diversity, 8 (2), 127-134. doi: 10.1023/B:MODI.0000025656.79632.86 |
|
2003 Journal Article The combinatorial synthesis of bicyclic privileged structures or privileged substructuresHorton, DA, Bourne, GT and Smythe, ML (2003). The combinatorial synthesis of bicyclic privileged structures or privileged substructures. Chemical Reviews, 103 (3), 893-930. doi: 10.1021/cr020033s |
|
2003 Journal Article Difficult macrocyclizations: New strategies for synthesizing highly strained cyclic tetrapeptidesMeutermans, W., Bourne, G. T., Golding, S., Horton, D., Campitelli, M. R., Craik, D. J., Scanlon, M. J. and Smythe, M. L. (2003). Difficult macrocyclizations: New strategies for synthesizing highly strained cyclic tetrapeptides. Organic Letters, 5 (15), 2711-2714. doi: 10.1021/ol034907o |
|
2002 Journal Article Exploring privileged structures: the combinatorial synthesis of cyclic peptidesHorton, D. A., Bourne, G. T. and Smythe, M. L. (2002). Exploring privileged structures: the combinatorial synthesis of cyclic peptides. Journal of Computer-aided Molecular Design, 16 (5-6), 415-431. doi: 10.1023/A:1020863921840 |
|
2002 Journal Article A subset-oriented algorithm for minimizing the number of steps required for synthesis of cyclic-peptide librariesTran, T. T., Bryant, D. E. and Smythe, M. L. (2002). A subset-oriented algorithm for minimizing the number of steps required for synthesis of cyclic-peptide libraries. Computers and Chemistry, 26 (2), 113-117. doi: 10.1016/S0097-8485(01)00087-0 |
|
2002 Journal Article A subset-orientated algorithm for minimizing the number of steps required for synthesis of cyclic-peptide librariesTran, Tran Trung, Bryant, Darryn and Smythe, Mark (2002). A subset-orientated algorithm for minimizing the number of steps required for synthesis of cyclic-peptide libraries. Computers and Chemistry, 26 (2), 113-7. doi: 10.1016/S0097-8485(01)00087-0 |
|
2001 Journal Article The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptidesBourne, Gregory T., Golding, Simon W., McGeary, Ross P., Meutermans, Wim D. F., Jones, Alun, Marshall, Garland R., Alewood, Paul F. and Smythe, Mark L. (2001). The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides. Journal of Organic Chemistry, 66 (23), 7706-7713. doi: 10.1021/jo010580y |
|
2001 Journal Article Synthesis of a cyclic peptide library based on the somatostatin sequence using the backbone amide linker approachBourne, G.T., Golding, S., Meutermans, W. and Smythe, M.L. (2001). Synthesis of a cyclic peptide library based on the somatostatin sequence using the backbone amide linker approach. Letters in Peptide Science, 7 (6), 311-316. doi: 10.1023/A:1013057832044 |
|
2001 Journal Article Proteolysis of human hemoglobin by schistosome cathepsin DBrindley, P. J., Kalinna, B. H., Wong, J. Y. M., Bogitsh, B. J., King, L. T., Smyth, D. J., Verity, C. K., Abbenante, G., Brinkworth, R. I., Fairlie, D. P., Smythe, M. L., Milburn, P. J., Bielefeldt-Ohmann, H., Zheng, Y. and McManus, D. P. (2001). Proteolysis of human hemoglobin by schistosome cathepsin D. Molecular And Biochemical Parasitology, 112 (1), 103-112. doi: 10.1016/S0166-6851(00)00351-0 |
|
2000 Journal Article An Activated O N Acyl Transfer Auxiliary: Efficient Amide-Backbone Substitution of Hindered "Difficult" PeptidesMiranda, L. P., Meutermans, W. D. F., Smythe, M. L. and Alewood, P.F. (2000). An Activated O N Acyl Transfer Auxiliary: Efficient Amide-Backbone Substitution of Hindered "Difficult" Peptides. Journal of Organic Chemistry, 65 (18), 5460-5468. doi: 10.1021/jo991340+ |
|
2000 Journal Article Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistryBattersby, Bronwyn J., Bryant, Darryn, Meutermans, Wim, Matthews, Daniel, Smythe, Mark L. and Trau, Matt (2000). Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistry. Journal of the American Chemical Society, 122 (9), 2138-2139. doi: 10.1021/ja993634i |
|
2000 Journal Article Synthesis of difficult cyclic peptides by inclusion of a novel photolabile auxiliary in a ring contraction strategyScolastico, C., Manzoni, L., Meutermans, W. D.F., Golding, S. W., Bourne, G. T., Miranda, L. P., Dooley, M. J., Alewood, P. F. and Smythe, M. L. (2000). Synthesis of difficult cyclic peptides by inclusion of a novel photolabile auxiliary in a ring contraction strategy. Chemtracts, 13 (7), 443-446. |
|
2000 Journal Article Exploring privileged structures: The combinatorial synthesis of cyclic peptidesHorton, DA, Bourne, GT and Smythe, ML (2000). Exploring privileged structures: The combinatorial synthesis of cyclic peptides. Molecular Diversity, 5 (4), 289-304. doi: 10.1023/A:1021365402751 |
|
1999 Journal Article The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptidesBourne, G. T., Meutermans, W. D. F. and Smythe, M. L. (1999). The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptides. Tetrahedron Letters, 40 (40), 7271-7274. doi: 10.1016/S0040-4039(99)01473-2 |
|
1999 Journal Article A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1Bourne, GT, Meutermans, WDF, Alewood, PF, McGeary, RP, Watson, AA and Smythe, ML (1999). A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1. Journal of Organic Chemistry, 64 (9), 3095-3101. doi: 10.1021/jo9818780 |
|
1997 Journal Article Proteolytic degradation of host hemoglobin by schistosomesBrindley, Paul J., Kalinna, Bernd H., Dalton, John P., Day, Sharon R., Wong, Joanna Y. M., Smythe, Mark L. and McManus, Donald P. (1997). Proteolytic degradation of host hemoglobin by schistosomes. Molecular and Biochemical Parasitology, 89 (1), 1-9. doi: 10.1016/S0166-6851(97)00098-4 |
|
1997 Journal Article Synthesis of α-aspartyl-containing cyclic peptidesMeutermans W.D.F., Alewood P.F., Bourne G.T., Hawkins B. and Smythe M.L. (1997). Synthesis of α-aspartyl-containing cyclic peptides. Letters in Peptide Science, 4 (2), 79-84. doi: 10.1007/BF02443518 |
|
1997 Journal Article Synthesis of alpha-aspartyl-containing cyclic peptidesMeutermans, WDF, Alewood, PF, Bourne, GT, Hawkins, B and Smythe, ML (1997). Synthesis of alpha-aspartyl-containing cyclic peptides. Letters In Peptide Science, 4 (2), 79-84. doi: 10.1023/A:1008878017315 |
