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2024 Journal Article The node of Ranvier influences the in vivo axonal transport of mitochondria and signalling endosomesTosolini, Andrew Paul, Abatecola, Federico, Negro, Samuele, Sleigh, James Nicholas and Schiavo, Giampietro (2024). The node of Ranvier influences the in vivo axonal transport of mitochondria and signalling endosomes. |
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2022 Journal Article BDNF-dependent modulation of axonal transport is selectively impaired in ALSTosolini, Andrew P., Sleigh, James N., Surana, Sunaina, Rhymes, Elena R., Cahalan, Stephen D. and Schiavo, Giampietro (2022). BDNF-dependent modulation of axonal transport is selectively impaired in ALS. Acta Neuropathologica Communications, 10 (1) 121, 1-17. doi: 10.1186/s40478-022-01418-4 |
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2021 Journal Article Expanding the toolkit for in vivo imaging of axonal transportTosolini, Andrew P., Villarroel-Campos, David, Schiavo, Giampietro and Sleigh, James N. (2021). Expanding the toolkit for in vivo imaging of axonal transport. Journal of Visualized Experiments, 2021 (178) e63471. doi: 10.3791/63471 |
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2023 Journal Article BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regenerationVargas, J. N. S, Brown, A. L., Sun, K., Hagemann, C., Geary, B., Villarroel-Campos, D., Bryce-Smith, S., Zanovello, M., Lombardo, M., Ryandov, E., Stepic, A., Meysman, L., Majewski, S., Tosolini, A. P., Secrier, M., Keuss, M. J., Serio, A., Sleigh, J. N., Fratta, P. and Schiavo, G. (2023). BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regeneration. |
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2023 Journal Article Gene therapy for the central and peripheral nervous system: volume IITosolini, Andrew P. and Smith, George M. (2023). Gene therapy for the central and peripheral nervous system: volume II. Frontiers in Molecular Neuroscience, 16 1258458, 01-03. doi: 10.3389/fnmol.2023.1258458 |
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2023 Journal Article Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D miceSleigh, James N., Villarroel-Campos, David, Surana, Sunaina, Wickenden, Tahmina, Tong, Yao, Simkin, Rebecca L., Vargas, Jose Norberto S., Rhymes, Elena R., Tosolini, Andrew P., West, Steven J., Zhang, Qian, Yang, Xiang-Lei and Schiavo, Giampietro (2023). Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice. JCI Insight, 8 (9) e157191. doi: 10.1172/jci.insight.157191 |
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2022 Journal Article Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factorNegro, Samuele, Lauria, Fabio, Stazi, Marco, Tebaldi, Toma, D’Este, Giorgia, Pirazzini, Marco, Megighian, Aram, Lessi, Francesca, Mazzanti, Chiara M., Sales, Gabriele, Romualdi, Chiara, Fillo, Silvia, Lista, Florigio, Sleigh, James N., Tosolini, Andrew P., Schiavo, Giampietro, Viero, Gabriella and Rigoni, Michela (2022). Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor. Acta Neuropathologica Communications, 10 (1) 189, 1-22. doi: 10.1186/s40478-022-01495-5 |
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2022 Journal Article Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neuronsRhymes, Elena R., Tosolini, Andrew P., Fellows, Alexander D., Mahy, William, McDonald, Neil Q. and Schiavo, Giampietro (2022). Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons. Cell Death and Disease, 13 (7) 584, 1-11. doi: 10.1038/s41419-022-05031-0 |
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2021 Journal Article Editorial: Dysfunction and Repair of Neural Circuits for Motor ControlTosolini, Andrew Paul, Mentis, George Z. and Martin, John H. (2021). Editorial: Dysfunction and Repair of Neural Circuits for Motor Control. Frontiers in Molecular Neuroscience, 14 669824. doi: 10.3389/fnmol.2021.669824 |
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2020 Journal Article Intramuscular delivery of gene therapy for targeting the nervous systemTosolini, Andrew P. and Sleigh, James N. (2020). Intramuscular delivery of gene therapy for targeting the nervous system. Frontiers in Molecular Neuroscience, 13 129. doi: 10.3389/fnmol.2020.00129 |
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2020 Journal Article Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomesSleigh, James N., Tosolini, Andrew P., Gordon, David, Devoy, Anny, Fratta, Pietro, Fisher, Elizabeth M.C., Talbot, Kevin and Schiavo, Giampietro (2020). Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomes. Cell Reports, 30 (11) 362546, 3655-3662e2. doi: 10.1016/j.celrep.2020.02.078 |
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2020 Journal Article Travelling Together: A Unifying Pathomechanism for ALSFratta, Pietro, Birsa, Nicol, Tosolini, Andrew P. and Schiavo, Giampietro (2020). Travelling Together: A Unifying Pathomechanism for ALS. Trends in Neurosciences, 43 (1), 1-2. doi: 10.1016/j.tins.2019.10.006 |
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2019 Journal Article The evolution of the axonal transport toolkitSurana, Sunaina, Villarroel-Campos, David, Lazo, Oscar M., Moretto, Edoardo, Tosolini, Andrew P., Rhymes, Elena R., Richter, Sandy, Sleigh, James N. and Schiavo, Giampietro (2019). The evolution of the axonal transport toolkit. Traffic, 21 (1), 13-33. doi: 10.1111/tra.12710 |
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2019 Journal Article Assessing rat forelimb and hindlimb motor unit connectivity as objective and robust biomarkers of spinal motor neuron functionHarrigan, Markus E., Filous, Angela R., Tosolini, Andrew P., Morris, Renee, Schwab, Jan M. and Arnold, W. David (2019). Assessing rat forelimb and hindlimb motor unit connectivity as objective and robust biomarkers of spinal motor neuron function. Scientific Reports, 9 (1) 16699, 1-14. doi: 10.1038/s41598-019-53235-w |
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2019 Journal Article Axonal transport and neurological diseaseSleigh, James N., Rossor, Alexander M., Fellows, Alexander D., Tosolini, Andrew P. and Schiavo, Giampietro (2019). Axonal transport and neurological disease. Nature Reviews Neurology, 15 (12), 691-703. doi: 10.1038/s41582-019-0257-2 |
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2019 Journal Article Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibitionKalinski, Ashley L., Kar, Amar N., Craver, John, Tosolini, Andrew P., Sleigh, James N., Lee, Seung Joon, Hawthorne, Alicia, Brito-Vargas, Paul, Miller-Randolph, Sharmina, Passino, Ryan, Shi, Liang, Wong, Victor S.C., Picci, Cristina, Smith, Deanna S., Willis, Dianna E., Havton, Leif A., Schiavo, Giampietro, Giger, Roman J., Langley, Brett and Twiss, Jeffery L. (2019). Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. Journal of Cell Biology, 218 (6) jcb.201702187, 1871-1890. doi: 10.1083/jcb.201702187 |
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2018 Journal Article The travel diaries of tetanus and botulinum neurotoxinsSurana, Sunaina, Tosolini, Andrew P., Meyer, Ione F.G., Fellows, Alexander D., Novoselov, Sergey S. and Schiavo, Giampietro (2018). The travel diaries of tetanus and botulinum neurotoxins. Toxicon, 147, 58-67. doi: 10.1016/j.toxicon.2017.10.008 |
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2018 Journal Article Editorial: Gene therapy for the central and peripheral nervous systemTosolini, Andrew P. and Smith, George M. (2018). Editorial: Gene therapy for the central and peripheral nervous system. Frontiers in Molecular Neuroscience, 11 54. doi: 10.3389/fnmol.2018.00054 |
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2017 Journal Article Motor neuron gene therapy: lessons from spinal muscular atrophy for amyotrophic lateral sclerosisTosolini, Andrew P. and Sleigh, James N. (2017). Motor neuron gene therapy: lessons from spinal muscular atrophy for amyotrophic lateral sclerosis. Frontiers in Molecular Neuroscience, 10 405. doi: 10.3389/fnmol.2017.00405 |
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2016 Journal Article Targeting motor end plates for delivery of adenoviruses: an approach to maximize uptake and transduction of spinal cord motor neuronsTosolini, Andrew Paul and Morris, Reneé (2016). Targeting motor end plates for delivery of adenoviruses: an approach to maximize uptake and transduction of spinal cord motor neurons. Scientific Reports, 6 (1) 33058, 1-14. doi: 10.1038/srep33058 |
