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Featured

2024

Journal Article

The node of Ranvier influences the in vivo axonal transport of mitochondria and signalling endosomes

Tosolini, Andrew Paul, Abatecola, Federico, Negro, Samuele, Sleigh, James Nicholas and Schiavo, Giampietro (2024). The node of Ranvier influences the in vivo axonal transport of mitochondria and signalling endosomes.

The node of Ranvier influences the in vivo axonal transport of mitochondria and signalling endosomes

Featured

2022

Journal Article

BDNF-dependent modulation of axonal transport is selectively impaired in ALS

Tosolini, Andrew P., Sleigh, James N., Surana, Sunaina, Rhymes, Elena R., Cahalan, Stephen D. and Schiavo, Giampietro (2022). BDNF-dependent modulation of axonal transport is selectively impaired in ALS. Acta Neuropathologica Communications, 10 (1) 121, 1-17. doi: 10.1186/s40478-022-01418-4

BDNF-dependent modulation of axonal transport is selectively impaired in ALS

Featured

2021

Journal Article

Expanding the toolkit for in vivo imaging of axonal transport

Tosolini, Andrew P., Villarroel-Campos, David, Schiavo, Giampietro and Sleigh, James N. (2021). Expanding the toolkit for in vivo imaging of axonal transport. Journal of Visualized Experiments, 2021 (178) e63471. doi: 10.3791/63471

Expanding the toolkit for in vivo imaging of axonal transport

2024

Conference Publication

In vivo axonal transport of mitochondria and signalling endosomes at the node of Ranvier

Tosolini, Andrew P., Abatecola, Federico, Negro, Samuele, Sleigh, James N. and Schiavo, Giampietro (2024). In vivo axonal transport of mitochondria and signalling endosomes at the node of Ranvier. 14th Queensland Cell and Developmental Biology Meeting, Brisbane, QLD, Australia, 3 June 2024.

In vivo axonal transport of mitochondria and signalling endosomes at the node of Ranvier

2023

Conference Publication

BDNF-dependent modulation of axonal transport is selectively impaired in Motor Neuron Disease

Tosolini, Andrew P., Sleigh, James N., Surana, Sunaina, Rhymes, Elena R., Cahalan, Stephen D. and Schiavo, Giampietro (2023). BDNF-dependent modulation of axonal transport is selectively impaired in Motor Neuron Disease. Australasian Neuroscience Society - 41st Annual Scientific Meeting, Brisbane, Australia, 4-7 December 2023.

BDNF-dependent modulation of axonal transport is selectively impaired in Motor Neuron Disease

2023

Conference Publication

In vivo axonal transport of diverse organelles in ALS

Tosolini, Andrew P., Birsa, Nicol, Cunningham, Tom, Fisher, Elizabeth, Fratta, Pietro and Schiavo, Giampietro (2023). In vivo axonal transport of diverse organelles in ALS. CAMAND Conference - Cellular and Molecular Advances in Neurodegeneration, Brisbane, Australia, 3-4 December 2023.

In vivo axonal transport of diverse organelles in ALS

2023

Conference Publication

In vivo axonal transport of diverse organelles in MND

Tosolini, Andrew P., Sleigh, James N., Surana, Sunaina, Rhymes, Elena R., Birsa, Nicol, Cunningham, Tom, Fisher, Elizabeth M.C., Fratta, Pietro and Schiavo, Giampietro (2023). In vivo axonal transport of diverse organelles in MND. 4th Annual Griffith University Parkinson's Disease Network Symposium, Brisbane, QLD, Australia, 30 November 2023.

In vivo axonal transport of diverse organelles in MND

2023

Journal Article

BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regeneration

Vargas, J. N. S, Brown, A. L., Sun, K., Hagemann, C., Geary, B., Villarroel-Campos, D., Bryce-Smith, S., Zanovello, M., Lombardo, M., Ryandov, E., Stepic, A., Meysman, L., Majewski, S., Tosolini, A. P., Secrier, M., Keuss, M. J., Serio, A., Sleigh, J. N., Fratta, P. and Schiavo, G. (2023). BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regeneration.

BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regeneration

2023

Journal Article

Gene therapy for the central and peripheral nervous system: volume II

Tosolini, Andrew P. and Smith, George M. (2023). Gene therapy for the central and peripheral nervous system: volume II. Frontiers in Molecular Neuroscience, 16 1258458, 01-03. doi: 10.3389/fnmol.2023.1258458

Gene therapy for the central and peripheral nervous system: volume II

2023

Journal Article

Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice

Sleigh, James N., Villarroel-Campos, David, Surana, Sunaina, Wickenden, Tahmina, Tong, Yao, Simkin, Rebecca L., Vargas, Jose Norberto S., Rhymes, Elena R., Tosolini, Andrew P., West, Steven J., Zhang, Qian, Yang, Xiang-Lei and Schiavo, Giampietro (2023). Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice. JCI Insight, 8 (9) e157191. doi: 10.1172/jci.insight.157191

Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice

2023

Conference Publication

In vivo axonal transport of diverse organelles in MND

Tosolini, Andrew P., Sleigh, James N., Surana, Sunaina, Rhymes, Elena R., Birsa, Nicol, Cunningham, Tom, Fisher, Elizabeth, Schiavo, Giampietro and Fratta, Pietro (2023). In vivo axonal transport of diverse organelles in MND. Australia and New Zealand MND Research Symposium, Wollongong, NSW, Australia, 17-18 November 2023.

In vivo axonal transport of diverse organelles in MND

2023

Conference Publication

Axonal transport in MND

Tosolini, Andrew P. (2023). Axonal transport in MND. Australian and New Zealand MND Research Symposium, Wollongong, NSW, Australia, 17-18 November 2023.

Axonal transport in MND

2022

Journal Article

Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor

Negro, Samuele, Lauria, Fabio, Stazi, Marco, Tebaldi, Toma, D’Este, Giorgia, Pirazzini, Marco, Megighian, Aram, Lessi, Francesca, Mazzanti, Chiara M., Sales, Gabriele, Romualdi, Chiara, Fillo, Silvia, Lista, Florigio, Sleigh, James N., Tosolini, Andrew P., Schiavo, Giampietro, Viero, Gabriella and Rigoni, Michela (2022). Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor. Acta Neuropathologica Communications, 10 (1) 189, 1-22. doi: 10.1186/s40478-022-01495-5

Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor

2022

Journal Article

Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons

Rhymes, Elena R., Tosolini, Andrew P., Fellows, Alexander D., Mahy, William, McDonald, Neil Q. and Schiavo, Giampietro (2022). Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons. Cell Death and Disease, 13 (7) 584, 1-11. doi: 10.1038/s41419-022-05031-0

Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons

2021

Journal Article

Editorial: Dysfunction and Repair of Neural Circuits for Motor Control

Tosolini, Andrew Paul, Mentis, George Z. and Martin, John H. (2021). Editorial: Dysfunction and Repair of Neural Circuits for Motor Control. Frontiers in Molecular Neuroscience, 14 669824. doi: 10.3389/fnmol.2021.669824

Editorial: Dysfunction and Repair of Neural Circuits for Motor Control

2021

Conference Publication

Molecular mechanisms of interneuronal transfer of pathogenic molecules

Panzi, Chiara, Restani, Laura, Tosolini, Andrew, Massa, Verediana, Caleo, Matteo and Schiavo, Giampietro (2021). Molecular mechanisms of interneuronal transfer of pathogenic molecules. TOXINS 2021 Virtual Conference, Online, 16-17 January 2021. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.toxicon.2020.11.458

Molecular mechanisms of interneuronal transfer of pathogenic molecules

2020

Journal Article

Intramuscular delivery of gene therapy for targeting the nervous system

Tosolini, Andrew P. and Sleigh, James N. (2020). Intramuscular delivery of gene therapy for targeting the nervous system. Frontiers in Molecular Neuroscience, 13 129. doi: 10.3389/fnmol.2020.00129

Intramuscular delivery of gene therapy for targeting the nervous system

2020

Journal Article

Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomes

Sleigh, James N., Tosolini, Andrew P., Gordon, David, Devoy, Anny, Fratta, Pietro, Fisher, Elizabeth M.C., Talbot, Kevin and Schiavo, Giampietro (2020). Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomes. Cell Reports, 30 (11) 362546, 3655-3662e2. doi: 10.1016/j.celrep.2020.02.078

Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomes

2020

Book Chapter

In vivo imaging of anterograde and retrograde axonal transport in rodent peripheral nerves

Sleigh, James N., Tosolini, Andrew P. and Schiavo, Giampietro (2020). In vivo imaging of anterograde and retrograde axonal transport in rodent peripheral nerves. Axon degeneration: methods and protocols. (pp. 271-292) edited by Elisabetta Babetto. New York, NY, United States: Humana Press Inc.. doi: 10.1007/978-1-0716-0585-1_20

In vivo imaging of anterograde and retrograde axonal transport in rodent peripheral nerves

2020

Journal Article

Travelling Together: A Unifying Pathomechanism for ALS

Fratta, Pietro, Birsa, Nicol, Tosolini, Andrew P. and Schiavo, Giampietro (2020). Travelling Together: A Unifying Pathomechanism for ALS. Trends in Neurosciences, 43 (1), 1-2. doi: 10.1016/j.tins.2019.10.006

Travelling Together: A Unifying Pathomechanism for ALS