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2025

Journal Article

ZRSR2 loss causes aberrant splicing in JAK2V617F‐driven myeloproliferative neoplasm but is not sufficient to drive disease progression

Zhang, Ranran, Straube, Jasmin, Janardhanan, Yashaswini, Haldar, Rohit, Cooper, Leanne, Hayes, Noah, Laurore, Charles, Kim, Chulwoo J., Luskin, Marlise R., Lindsley, Robert C., Stahl, Maximilian, Mullally, Ann, Marneth, Anna E., Bywater, Megan and Lane, Steven W. (2025). ZRSR2 loss causes aberrant splicing in JAK2V617F‐driven myeloproliferative neoplasm but is not sufficient to drive disease progression. HemaSphere, 9 (9) e70225, 1-6. doi: 10.1002/hem3.70225

ZRSR2 loss causes aberrant splicing in JAK2V617F‐driven myeloproliferative neoplasm but is not sufficient to drive disease progression

2024

Conference Publication

3035 – INTERFERON ALPHA THERAPY ATTENUATES LEUKAEMIC TRANSFORMATION IN JAK2V617F-DRIVEN MPN WITH TRP53-LOSS

Bywater, Megan, Zhang, Ranran, Grabek, Julian, Halder, Rohit, Janardhanan, Yashaswini, Cooper, Leanne, Cooper, Emily, Ross, David, Straube, Jasmin and Lane, Steven (2024). 3035 – INTERFERON ALPHA THERAPY ATTENUATES LEUKAEMIC TRANSFORMATION IN JAK2V617F-DRIVEN MPN WITH TRP53-LOSS. EXPHEM 2024, Philadelphia, PA, United States: Elsevier BV. doi: 10.1016/j.exphem.2024.104357

3035 – INTERFERON ALPHA THERAPY ATTENUATES LEUKAEMIC TRANSFORMATION IN JAK2V617F-DRIVEN MPN WITH TRP53-LOSS

2024

Other Outputs

CRISPR-Cas9 approaches to model Myeloproliferative Neoplasms in vivo

Zhang, Ranran (2024). CRISPR-Cas9 approaches to model Myeloproliferative Neoplasms in vivo. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/0e84c4b

CRISPR-Cas9 approaches to model Myeloproliferative Neoplasms in vivo

2023

Conference Publication

Trp53-Loss in Hematopoietic Stem Cells Drives the Evolutionary Process of Leukemic Transformation in a Jak2 V617F-Driven Myeloproliferative Neoplasms Mouse Model

Zhang, Ranran, Janardhanan, Yashaswini, Haldar, Rohit, Cooper, Leanne, Jaquelin, Sebastien, Straube, Jasmin, Bywater, Megan and Lane, Steven W. (2023). Trp53-Loss in Hematopoietic Stem Cells Drives the Evolutionary Process of Leukemic Transformation in a Jak2 V617F-Driven Myeloproliferative Neoplasms Mouse Model. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-188150

Trp53-Loss in Hematopoietic Stem Cells Drives the Evolutionary Process of Leukemic Transformation in a Jak2 V617F-Driven Myeloproliferative Neoplasms Mouse Model

2021

Journal Article

Germline RUNX1 variation and predisposition to childhood acute lymphoblastic leukemia

Li, Yizhen, Yang, Wentao, Devidas, Meenakshi, Winter, Stuart S., Kesserwan, Chimene, Yang, Wenjian, Dunsmore, Kimberly P., Smith, Colton, Qian, Maoxiang, Zhao, Xujie, Zhang, Ranran, Gastier-Foster, Julie M., Raetz, Elizabeth A., Carroll, William L., Li, Chunliang, Liu, Paul P., Rabin, Karen R., Sanda, Takaomi, Mullighan, Charles G., Nichols, Kim E., Evans, William E., Pui, Ching-Hon, Hunger, Stephen P., Teachey, David T., Relling, Mary, Loh, Mignon L. and Yang, Jun J. (2021). Germline RUNX1 variation and predisposition to childhood acute lymphoblastic leukemia. Journal of Clinical Investigation, 131 (17) e147898, 1-14. doi: 10.1172/jci147898

Germline RUNX1 variation and predisposition to childhood acute lymphoblastic leukemia

2020

Journal Article

4-hydroxyphenyl retinamide preferentially targets FLT3 mutated acute myeloid leukemia via ROS induction and NF-kappa B inhibition

Zhao, Xin-ying, Zhang, Ran-ran, Ye, Qian, Qiu, Fei, Xu, Hao-yu, Wei, Feng-gui and Zhang, Hui (2020). 4-hydroxyphenyl retinamide preferentially targets FLT3 mutated acute myeloid leukemia via ROS induction and NF-kappa B inhibition. Current Medical Science, 40 (5), 810-816. doi: 10.1007/s11596-020-2259-0

4-hydroxyphenyl retinamide preferentially targets FLT3 mutated acute myeloid leukemia via ROS induction and NF-kappa B inhibition

2020

Journal Article

Chemosensitization by 4-hydroxyphenyl retinamide-induced NF-κB inhibition in acute myeloid leukemia cells

Zhang, Hui, Xu, Haoyu, Zhang, Ranran, Zhao, Xinying, Liang, Ming and Wei, Fenggui (2020). Chemosensitization by 4-hydroxyphenyl retinamide-induced NF-κB inhibition in acute myeloid leukemia cells. Cancer Chemotherapy and Pharmacology, 86 (2), 257-266. doi: 10.1007/s00280-020-04115-y

Chemosensitization by 4-hydroxyphenyl retinamide-induced NF-κB inhibition in acute myeloid leukemia cells

2019

Conference Publication

Germline RUNX1 variation and predisposition to T-cell acute lymphoblastic leukemia in children

Li, Yizhen, Qian, Maoxiang, Devidas, Meenakshi, Yang, Wentao, Winter, Stuart S., Dunsmore, Kimberly P., Smith, Colton A., Lin, Ting-Nien, Zhao, Xuijie, Zhang, Ranran, Foster, Julie M. Gastier, Raetz, Elizabeth A., Carroll, William L., Rabin, Karen R., Yang, Wenjian, Zweidler-McKay, Patrick A., Pui, Ching-Hon, Evans, William E., Mullighan, Charles G., Hunger, Stephen P., Relling, Mary V., Loh, Mignon L. and Yang, Jun J. (2019). Germline RUNX1 variation and predisposition to T-cell acute lymphoblastic leukemia in children. 61st Annual Meeting of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-125912

Germline RUNX1 variation and predisposition to T-cell acute lymphoblastic leukemia in children

2018

Journal Article

Germline genetic IKZF1 variation and predisposition to childhood acute lymphoblastic leukemia

Churchman, Michelle L., Qian, Maoxiang, te Kronnie, Geertruy, Zhang, Ranran, Yang, Wenjian, Zhang, Hui, Lana, Tobia, Tedrick, Paige, Baskin, Rebekah, Verbist, Katherine, Peters, Jennifer L., Devidas, Meenakshi, Larsen, Eric, Moore, Ian M., Gu, Zhaohui, Qu, Chunxu, Yoshihara, Hiroki, Porter, Shaina N., Pruett-Miller, Shondra M., Wu, Gang, Raetz, Elizabeth, Martin, Paul L., Bowman, W. Paul, Winick, Naomi, Mardis, Elaine, Fulton, Robert, Stanulla, Martin, Evans, William E., Relling, Mary V. ... Mullighan, Charles G. (2018). Germline genetic IKZF1 variation and predisposition to childhood acute lymphoblastic leukemia. Cancer Cell, 33 (5), 937-948. doi: 10.1016/j.ccell.2018.03.021

Germline genetic IKZF1 variation and predisposition to childhood acute lymphoblastic leukemia

2017

Journal Article

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP

Qian, Maoxiang, Zhang, Hui, Kham, Shirley Kow-Yin, Liu, Shuguang, Jiang, Chuang, Zhao, Xujie, Lu, Yi, Goodings, Charnise, Lin, Ting-Nien, Zhang, Ranran, Moriyama, Takaya, Yin, Zhaohong, Li, Zhenhua, Quah, Thuan Chong, Ariffin, Hany, Tan, Ah Moy, Shen, Shuhong, Bhojwani, Deepa, Hu, Shaoyan, Chen, Suning, Zheng, Huyong, Pui, Ching-Hon, Yeoh, Allen Eng-Juh and Yang, Jun J. (2017). Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP. Genome Research, 27 (2), 185-195. doi: 10.1101/gr.209163.116

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP

2016

Conference Publication

Whole transcriptome sequencing identified a distinct subtype of acute lymphoblastic leukemia with abnormalities of CREBBP and EP300

Zhang, Hui, Qian, Maoxiang, Shirley,, Kham, Kow Yin, Liu, Shuguang, Jiang, Chuang, Zhao, Xujie, Lu, Yi, Lin, Ting-Nien, Zhang, Ranran, Moriyama, Takaya, Yin, Zhaohong, Shi, Lei, Li, Zhenhua, Chiew, Kean-Hui, Chen, Zhiwei, Deepa, Bhojwani, Shen, Shuhong, Zheng, Huyong, Pui, Ching-Hon, Yeoh, Allen Eng Juh and Yang, Jun J. (2016). Whole transcriptome sequencing identified a distinct subtype of acute lymphoblastic leukemia with abnormalities of CREBBP and EP300. 58th Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.v128.22.3912.3912

Whole transcriptome sequencing identified a distinct subtype of acute lymphoblastic leukemia with abnormalities of CREBBP and EP300

2016

Conference Publication

Germline genetic variation in IKZF1 and predisposition to childhood acute lymphoblastic leukemia

Churchman, Michelle L., Qian, Maoxiang, Zhang, Ranran, Kronnie, Geertruy, Yang, Wenjian, Zhang, Hui, Lana, Tobia, Tedrick, Paige, Baskin, Rebekah, Verbist, Katherine, Devidas, Meenakshi, Raetz, Elizabeth, Larsen, Eric, Martin, Paul L., Bowman, W. Paul, Winick, Naomi, Mardis, Elaine R, Fulton, Robert S., Stanulla, Martin, Evans, William E., Relling, Mary V., Pui, Ching-Hon, Handgretinger, Rupert, Hunger, Stephen P., Loh, Mignon L., Nichols, Kim E., Mullighan, Charles and Yang, Jun J. (2016). Germline genetic variation in IKZF1 and predisposition to childhood acute lymphoblastic leukemia. 58th ASH Annual Meeting, San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.v128.22.lba-2.lba-2

Germline genetic variation in IKZF1 and predisposition to childhood acute lymphoblastic leukemia

2016

Conference Publication

Chemosensitizing effect of Fenretinide-induced NF-κb inhibition in AML therapy

Zhang, Ranran, Fenggui, Wei, Chen, Ru, Liang, Ming, Wu, Liping, Zhang, Hui and Chen, Fuxiong (2016). Chemosensitizing effect of Fenretinide-induced NF-κb inhibition in AML therapy. 58th ASH Annual Meeting, San Diego, CA United States, 3-6 December 2016. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.v128.22.1580.1580

Chemosensitizing effect of Fenretinide-induced NF-κb inhibition in AML therapy

2015

Journal Article

Research progress on chemoresistance mechanism of nuclear factor kappa B signalling patheway in acute myeloid leukemia

Zhang, Ran-Ran, Zhang, Hui and Chen, Fu-Xiong (2015). Research progress on chemoresistance mechanism of nuclear factor kappa B signalling patheway in acute myeloid leukemia. Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology, 23 (6), 1785-1790. doi: 10.7534/j.issn.1009-2137.2015.06.046

Research progress on chemoresistance mechanism of nuclear factor kappa B signalling patheway in acute myeloid leukemia