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2025 Journal Article The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort StudySubramaniam, Ashwin, Ling, Ryan Ruiyang, Burrell, Aidan, Moran, Benjamin, Ramanan, Mahesh, Ramanathan, Kollengode, Reddy, Mallikarjuna Ponnapa, Pilcher, David and Shekar, Kiran (2025). The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study. Critical Care Medicine, 53 (12), 1-11. doi: 10.1097/ccm.0000000000006917 |
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2025 Journal Article A contemporary narrative review of sodium homeostasis mechanisms, dysnatraemia, and the clinical relevance in adult critical illnessRaman, Vignesh, Ramanan, Mahesh, Edwards, Felicity and Laupland, Kevin B. (2025). A contemporary narrative review of sodium homeostasis mechanisms, dysnatraemia, and the clinical relevance in adult critical illness. Journal of Clinical Medicine, 14 (19) 6914, 1-14. doi: 10.3390/jcm14196914 |
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2025 Journal Article The dawn of target trials in Intensive Care: time to move beyond association is not causation. Authors’ replyBlank, Sebastiaan Paul, Blank, Ruth Miriam, Laupland, Kevin B., White, Kyle C. and Ramanan, Mahesh (2025). The dawn of target trials in Intensive Care: time to move beyond association is not causation. Authors’ reply. Intensive Care Medicine, 51 (9), 1734-1735. doi: 10.1007/s00134-025-08018-5 |
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2025 Journal Article Sodium bicarbonate in critical illness: targeted or too broad? Author’s replyBlank, Ruth Miriam, Blank, Sebastiaan Paul, Laupland, Kevin B., White, Kyle C. and Ramanan, Mahesh (2025). Sodium bicarbonate in critical illness: targeted or too broad? Author’s reply. Intensive Care Medicine, 51 (10), 1-2. doi: 10.1007/s00134-025-08091-w |
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2025 Conference Publication Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational StudyAshby, A., Anstey, C., Attokaran, A., Siriwarden, M., Mullany, D., Kumar, A., Pryke, C., Laupland, K., Tabah, A., Shekar, K., Blank, S., Whebell, S., Luke, S., Raman, S., Garrett, P., McCullough, J., White, K. and Ramanan, M. (2025). Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Sydney, NSW Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.237 |
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2025 Journal Article Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulationBlank, Sebastiaan Paul, Blank, Ruth Miriam, Laupland, Kevin B., Tabah, Alexis, Gill, Denzil, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, McCullough, James, McIlroy, Philippa, Ramanan, Mahesh, Keogh, Sam, Tyack, Zephanie, Gatton, Michelle, Nash, Ben, Blank, Sebastiaan, Dash, Sananta, Senthuran, Siva, Smart, Christopher, Taylor, Jennifer, Paasilahti, Anni, Reoch, Josephine, Poggenpoel, Jaco, Attokaran, Antony G., Anderson, Cameron, Lutshaba, Langa ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation. Intensive Care Medicine, 51 (6), 1078-1086. doi: 10.1007/s00134-025-07979-x |
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2025 Journal Article The impact of critical illness on the outcomes of cardiac surgery in patients with acute infective endocarditisMatebele, Mbakise P., Vemuri, Kanthi R., Sedgwick, John F., Marshall, Lachlan, Horvath, Robert, Obonyo, Nchafatso G. and Ramanan, Mahesh (2025). The impact of critical illness on the outcomes of cardiac surgery in patients with acute infective endocarditis. Hearts, 6 (2) 15, 1-14. doi: 10.3390/hearts6020015 |
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2025 Journal Article Impact of frailty on outcomes after cardiac surgeryAhuja, Abhilasha, Baker, Thomas and Ramanan, Mahesh (2025). Impact of frailty on outcomes after cardiac surgery. Journal of Thoracic and Cardiovascular Surgery, 169 (6), 1787-1794.e9. doi: 10.1016/j.jtcvs.2024.05.025 |
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2025 Journal Article Fludrocortisone to treat patients with aneurysmal subarachnoid haemorrhage: Protocol for an international, phase 3, randomised, placebo-controlled, multicentre trialCohen, Jeremy, Delaney, Anthony, Udy, Andrew, Andersen, Christopher, Anderson, Craig S., Bellapart, Judith, Burrell, Louise M., Devaux, Anthony, Evans, David M., Fitzgerald, Emily, Garside, Tessa, Hammond, Naomi, Hardie, Miranda, Jeffree, Rosalind L., Knowles, Serena, Lassig-Smith, Melissa, Li, Qiang, Nethathe, Gladness, Rajbhandari, Dorrilyn, Ramanan, Mahesh, Talbot, Philip, Taylor, Colman, Wright, Jason, Young, Morag J., Young, Paul J. and Venkatesh, Balasubramanian (2025). Fludrocortisone to treat patients with aneurysmal subarachnoid haemorrhage: Protocol for an international, phase 3, randomised, placebo-controlled, multicentre trial. Critical Care and Resuscitation, 27 (2) 100116, 1-7. doi: 10.1016/j.ccrj.2025.100116 |
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2025 Journal Article Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international studyWhite, Kyle C., Bellomo, Rinaldo, Laupland, Kevin B., Gatton, Michelle L., Ostermann, Marlies, McIlroy, Philipa, Luke, Stephen, Garrett, Peter, Tabah, Alexis, Whebell, Stephen, Marella, Prashanti, McCullough, James, Shekar, Kiran, Attokaran, Antony G., Kumar, Aashish, Meyer, Jason, Sanderson, Barnaby, Serpa-Neto, Ary, Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study. Journal of Critical Care, 87 155016, 1-9. doi: 10.1016/j.jcrc.2025.155016 |
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2025 Journal Article Respiratory syncytial virus infection in adult and paediatric patients admitted to intensive care in Australia: a nation-wide comparison with COVID-19Tang, Yaodong, Zhao, Peinan, Cheng, Allen C., Ibrahim, Aaliya, Hassall, Jenna, Litton, Edward, Andersen, Christopher R., Liang, Cindy, Milford, Elissa M., Rose, Morgan, Plummer, Mark, Kong, Jing, Johnson, Kerry, Bihari, Shailesh, Chaba, Anis, Begum, Husna, Cruz, Sherene Magana, Ng, Sze, Trapani, Tony, Campbell, Lewis, Ramanan, Mahesh, McAllister, Richard, Chumbes, Jenipher, Erickson, Simon, Kol, Mark, Cheung, Winston, Udy, Andrew A. and Burrell, Aidan (2025). Respiratory syncytial virus infection in adult and paediatric patients admitted to intensive care in Australia: a nation-wide comparison with COVID-19. Critical Care and Resuscitation, 27 (2) 100113, 1-7. doi: 10.1016/j.ccrj.2025.100113 |
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2025 Journal Article A randomised, controlled, feasibility trial comparing vasopressors infused via peripheral cannula versus central venous access for critically ill adults: the VIPCA trialRamanan, Mahesh, Apte, Yogesh, Watts, Stacey, Holland, Thomas, Hatt, April, Craswell, Alison, Lin, Frances, Tabah, Alexis, Ware, Robert S., Byrnes, Joshua, Anstey, Christopher and Keijzers, Gerben (2025). A randomised, controlled, feasibility trial comparing vasopressors infused via peripheral cannula versus central venous access for critically ill adults: the VIPCA trial. Critical Care and Resuscitation, 27 (2) 100106, 1-8. doi: 10.1016/j.ccrj.2025.100106 |
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2025 Journal Article Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational studyZimsen, Tarren, Quick, Lachlan, White, Gentry, Costa-Pinto, Rahul, Whebell, Stephen, Meyer, Jason, McCullough, James, Shekar, Kiran, Laupland, Kevin B., Ramanan, Mahesh, Blank, Sebastiaan, Tabah, Alexis, Luke, Stephen, Garrett, Peter, Attokaran, Antony G., Kumar, Aashish and White, Kyle C. (2025). Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study. Critical Care and Resuscitation, 27 (2) 100112, 100112. doi: 10.1016/j.ccrj.2025.100112 |
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2025 Journal Article Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trialNiemelä, V. H., Reinikainen, M., Nielsen, N., Bass, F., Young, P., Lilja, G., Dankiewicz, J., Hammond, N., Hästbacka, J., Levin, H., Moseby‐Knappe, M., Saxena, M., Tiainen, M., Ceric, A., Holgersson, J., Kamp, C. B., Tirkkonen, J., Oksanen, T., Kaakinen, T., Bendel, S., Düring, J., Lybeck, A., Johnsson, J., Unden, J., Lundin, A., Kåhlin, J., Grip, J., Lotman, E., Romundstad, L. ... Skrifvars, M. B. (2025). Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (6) e70040, 1-11. doi: 10.1111/aas.70040 |
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2025 Journal Article Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulationWhite, Kyle C., Costa-Pinto, Rahul, Blank, Sebastiaan, Whebell, Stephen, Quick, Lachlan, Luke, Stephen, Attokaran, Antony G., Garrett, Peter, Ramanan, Mahesh, Tabah, Alexis, Shekar, Kiran, Laupland, Kevin B., Kumar, Aashish, McCullough, James, Udy, Andrew, Eastwood, Glenn, Bellomo, Rinaldo, Chaba, Anis, the Queensland Critical Care Research Network (QCCRN), Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David ... Keogh, Sam (2025). Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation. Critical Care, 29 (1) 188, 1-10. doi: 10.1186/s13054-025-05401-y |
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2025 Journal Article Tracking outcomes post intensive care: findings of a longitudinal observational studyFlaws, Dylan, Tronstad, Oystein, Fraser, John F., Lavana, Jayshree, Laupland, Kevin B., Ramanan, Mahesh, Tabah, Alexis and Patterson, Sue (2025). Tracking outcomes post intensive care: findings of a longitudinal observational study. Australian Critical Care, 38 (3) 101164, 1-8. doi: 10.1016/j.aucc.2024.101164 |
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2025 Journal Article Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trialCeric, A., Dankiewicz, J., Hästbacka, J., Young, P., Niemelä, V. H., Bass, F., Skrifvars, M. B., Hammond, N., Saxena, M., Levin, H., Lilja, G., Moseby-Knappe, M., Tiainen, M., Reinikainen, M., Holgersson, J., Kamp, C. B., Wise, M. P., McGuigan, P. J., White, J., Sweet, K., Keeble, T. R., Glover, G., Hopkins, P., Remmington, C., Cole, J. M., Gorgoraptis, N., Pogson, D. G., Jackson, P., Düring, J. ... Nielsen, N. (2025). Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (5) e70022, 1-13. doi: 10.1111/aas.70022 |
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2025 Journal Article Fever management with or without a temperature control device after out‐of‐hospital cardiac arrest and resuscitation (TEMP‐CARE): A study protocol for a randomized clinical trialHolgersson, Johan, Niemelä, V., Skrifvars, M. B., Kamp‐Jorgensen, C., Saxena, M., Young, P., Bass, F., Dankiewicz, J., Hammond, N., Hästbacka, J., Levin, H., Lilja, G., Moseby‐Knappe, M., Tiainen, M., Reinikainen, M., Ceric, A., Düring, J., Lybeck, A., Rodriguez‐Santos, D., Johnsson, J., Unden, J., Lundin, A., Kåhlin, J., Grip, J., Rosell, J., Lotman, E. M., Navarra, L., Crichton, B., Knight, D. ... Nielsen, N. (2025). Fever management with or without a temperature control device after out‐of‐hospital cardiac arrest and resuscitation (TEMP‐CARE): A study protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (5) e70034, 1-12. doi: 10.1111/aas.70034 |
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2025 Journal Article Research priorities for diabetic ketoacidosis: an evidence and gap mapping reviewSieben, Nicolas and Ramanan, Mahesh (2025). Research priorities for diabetic ketoacidosis: an evidence and gap mapping review. Medical Sciences, 13 (2) 53, 53-2. doi: 10.3390/medsci13020053 |
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2025 Journal Article Frailty and long-term survival in patients with critical illness after nonhome discharge: A retrospective cohort studyMehta, Hardik, Ling, Ryan Ruiyang, Ramanan, Mahesh, Bartlett, Catherine, Grewal, Jatinder, Gupta, Kshityj, Reynolds, James, Kumar, Aashish, Marella, Prashanti, Pilcher, David, Shah, Nilesh, Shekar, Kiran and Subramaniam, Ashwin (2025). Frailty and long-term survival in patients with critical illness after nonhome discharge: A retrospective cohort study. Critical Care Medicine, 53 (7), e1402-e1415. doi: 10.1097/ccm.0000000000006684 |
