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2025

Journal Article

Metabolic alkalosis acquired in intensive care: a retrospective cohort study

Goh, Gordon, Blank, Sebastiaan, Doola, Ra’eesa, Alder, Nelson, Ahuja, Abhilasha, Laupland, Kevin B., Tabah, Alexis, Shekar, Kiran, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, Nesbitt, Alexander, McCullough, James, McIlroy, Philippa and Ramanan, Mahesh (2025). Metabolic alkalosis acquired in intensive care: a retrospective cohort study. Anaesthesia Critical Care and Pain Medicine, 44 (6) 101591, 1-6. doi: 10.1016/j.accpm.2025.101591

Metabolic alkalosis acquired in intensive care: a retrospective cohort study

2025

Journal Article

The prevalence and use of arterial catheters in adult intensive care units: An Australian and New Zealand point prevalence study

Keogh, Samantha, Edwards, Felicity, Levido, Annabel, Alexandrou, Evan, Corley, Amanda, Coyer, Fiona, Dhanani, Jayesh, Gibbons, Kristen, Hammond, Naomi E., Knowles, Serena, Laupland, Kevin B., Ramanan, Mahesh, Rickard, Claire M. and Udy, Andrew (2025). The prevalence and use of arterial catheters in adult intensive care units: An Australian and New Zealand point prevalence study. Australian Critical Care, 38 (6) 101312, 1-8. doi: 10.1016/j.aucc.2025.101312

The prevalence and use of arterial catheters in adult intensive care units: An Australian and New Zealand point prevalence study

2025

Journal Article

Response to letter to the editor by Chen et al. regarding early psychiatric intervention assessment and intervention service pilot study

Flaws, Dylan, Baker, Stuart, Barnett, Adrian, Jacobs, Kylie, Metcalf, Olivia, Patterson, Sue, Pollock, Hamish, Proctor, Emma, Ramanan, Mahesh, Tabah, Alexis and Varker, Tracey (2025). Response to letter to the editor by Chen et al. regarding early psychiatric intervention assessment and intervention service pilot study. Australian Critical Care, 38 (6) 101452, 1-2. doi: 10.1016/j.aucc.2025.101452

Response to letter to the editor by Chen et al. regarding early psychiatric intervention assessment and intervention service pilot study

2025

Journal Article

The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study

Subramaniam, Ashwin, Ling, Ryan Ruiyang, Burrell, Aidan, Moran, Benjamin, Ramanan, Mahesh, Ramanathan, Kollengode, Reddy, Mallikarjuna Ponnapa, Pilcher, David and Shekar, Kiran (2025). The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study. Critical Care Medicine, 53 (12), 1-11. doi: 10.1097/ccm.0000000000006917

The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study

2025

Journal Article

Incidence of late-onset hyperlactatemia and association with clinical outcomes in intensive care patients

Kumar, Aashish, Turner, Andrew G., Laupland, Kevin B. and Ramanan, Mahesh (2025). Incidence of late-onset hyperlactatemia and association with clinical outcomes in intensive care patients. Critical Care Science, 37 e20250124, 1-7. doi: 10.62675/2965-2774.20250124

Incidence of late-onset hyperlactatemia and association with clinical outcomes in intensive care patients

2025

Journal Article

A contemporary narrative review of sodium homeostasis mechanisms, dysnatraemia, and the clinical relevance in adult critical illness

Raman, Vignesh, Ramanan, Mahesh, Edwards, Felicity and Laupland, Kevin B. (2025). A contemporary narrative review of sodium homeostasis mechanisms, dysnatraemia, and the clinical relevance in adult critical illness. Journal of Clinical Medicine, 14 (19) 6914, 1-14. doi: 10.3390/jcm14196914

A contemporary narrative review of sodium homeostasis mechanisms, dysnatraemia, and the clinical relevance in adult critical illness

2025

Journal Article

The dawn of target trials in Intensive Care: time to move beyond association is not causation. Authors’ reply

Blank, Sebastiaan Paul, Blank, Ruth Miriam, Laupland, Kevin B., White, Kyle C. and Ramanan, Mahesh (2025). The dawn of target trials in Intensive Care: time to move beyond association is not causation. Authors’ reply. Intensive Care Medicine, 51 (9), 1734-1735. doi: 10.1007/s00134-025-08018-5

The dawn of target trials in Intensive Care: time to move beyond association is not causation. Authors’ reply

2025

Journal Article

Sodium bicarbonate in critical illness: targeted or too broad? Author’s reply

Blank, Ruth Miriam, Blank, Sebastiaan Paul, Laupland, Kevin B., White, Kyle C. and Ramanan, Mahesh (2025). Sodium bicarbonate in critical illness: targeted or too broad? Author’s reply. Intensive Care Medicine, 51 (10), 1-2. doi: 10.1007/s00134-025-08091-w

Sodium bicarbonate in critical illness: targeted or too broad? Author’s reply

2025

Conference Publication

Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study

Ashby, A., Anstey, C., Attokaran, A., Siriwarden, M., Mullany, D., Kumar, A., Pryke, C., Laupland, K., Tabah, A., Shekar, K., Blank, S., Whebell, S., Luke, S., Raman, S., Garrett, P., McCullough, J., White, K. and Ramanan, M. (2025). Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Sydney, NSW Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.237

Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study

2025

Journal Article

Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation

Blank, Sebastiaan Paul, Blank, Ruth Miriam, Laupland, Kevin B., Tabah, Alexis, Gill, Denzil, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, McCullough, James, McIlroy, Philippa, Ramanan, Mahesh, Keogh, Sam, Tyack, Zephanie, Gatton, Michelle, Nash, Ben, Blank, Sebastiaan, Dash, Sananta, Senthuran, Siva, Smart, Christopher, Taylor, Jennifer, Paasilahti, Anni, Reoch, Josephine, Poggenpoel, Jaco, Attokaran, Antony G., Anderson, Cameron, Lutshaba, Langa ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation. Intensive Care Medicine, 51 (6), 1078-1086. doi: 10.1007/s00134-025-07979-x

Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation

2025

Journal Article

The impact of critical illness on the outcomes of cardiac surgery in patients with acute infective endocarditis

Matebele, Mbakise P., Vemuri, Kanthi R., Sedgwick, John F., Marshall, Lachlan, Horvath, Robert, Obonyo, Nchafatso G. and Ramanan, Mahesh (2025). The impact of critical illness on the outcomes of cardiac surgery in patients with acute infective endocarditis. Hearts, 6 (2) 15, 1-14. doi: 10.3390/hearts6020015

The impact of critical illness on the outcomes of cardiac surgery in patients with acute infective endocarditis

2025

Journal Article

A randomised, controlled, feasibility trial comparing vasopressors infused via peripheral cannula versus central venous access for critically ill adults: the VIPCA trial

Ramanan, Mahesh, Apte, Yogesh, Watts, Stacey, Holland, Thomas, Hatt, April, Craswell, Alison, Lin, Frances, Tabah, Alexis, Ware, Robert S., Byrnes, Joshua, Anstey, Christopher and Keijzers, Gerben (2025). A randomised, controlled, feasibility trial comparing vasopressors infused via peripheral cannula versus central venous access for critically ill adults: the VIPCA trial. Critical Care and Resuscitation, 27 (2) 100106, 1-8. doi: 10.1016/j.ccrj.2025.100106

A randomised, controlled, feasibility trial comparing vasopressors infused via peripheral cannula versus central venous access for critically ill adults: the VIPCA trial

2025

Journal Article

Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study

Zimsen, Tarren, Quick, Lachlan, White, Gentry, Costa-Pinto, Rahul, Whebell, Stephen, Meyer, Jason, McCullough, James, Shekar, Kiran, Laupland, Kevin B., Ramanan, Mahesh, Blank, Sebastiaan, Tabah, Alexis, Luke, Stephen, Garrett, Peter, Attokaran, Antony G., Kumar, Aashish and White, Kyle C. (2025). Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study. Critical Care and Resuscitation, 27 (2) 100112, 100112. doi: 10.1016/j.ccrj.2025.100112

Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study

2025

Journal Article

Impact of frailty on outcomes after cardiac surgery

Ahuja, Abhilasha, Baker, Thomas and Ramanan, Mahesh (2025). Impact of frailty on outcomes after cardiac surgery. Journal of Thoracic and Cardiovascular Surgery, 169 (6), 1787-1794.e9. doi: 10.1016/j.jtcvs.2024.05.025

Impact of frailty on outcomes after cardiac surgery

2025

Journal Article

Fludrocortisone to treat patients with aneurysmal subarachnoid haemorrhage: Protocol for an international, phase 3, randomised, placebo-controlled, multicentre trial

Cohen, Jeremy, Delaney, Anthony, Udy, Andrew, Andersen, Christopher, Anderson, Craig S., Bellapart, Judith, Burrell, Louise M., Devaux, Anthony, Evans, David M., Fitzgerald, Emily, Garside, Tessa, Hammond, Naomi, Hardie, Miranda, Jeffree, Rosalind L., Knowles, Serena, Lassig-Smith, Melissa, Li, Qiang, Nethathe, Gladness, Rajbhandari, Dorrilyn, Ramanan, Mahesh, Talbot, Philip, Taylor, Colman, Wright, Jason, Young, Morag J., Young, Paul J. and Venkatesh, Balasubramanian (2025). Fludrocortisone to treat patients with aneurysmal subarachnoid haemorrhage: Protocol for an international, phase 3, randomised, placebo-controlled, multicentre trial. Critical Care and Resuscitation, 27 (2) 100116, 1-7. doi: 10.1016/j.ccrj.2025.100116

Fludrocortisone to treat patients with aneurysmal subarachnoid haemorrhage: Protocol for an international, phase 3, randomised, placebo-controlled, multicentre trial

2025

Journal Article

Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study

White, Kyle C., Bellomo, Rinaldo, Laupland, Kevin B., Gatton, Michelle L., Ostermann, Marlies, McIlroy, Philipa, Luke, Stephen, Garrett, Peter, Tabah, Alexis, Whebell, Stephen, Marella, Prashanti, McCullough, James, Shekar, Kiran, Attokaran, Antony G., Kumar, Aashish, Meyer, Jason, Sanderson, Barnaby, Serpa-Neto, Ary, Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study. Journal of Critical Care, 87 155016, 1-9. doi: 10.1016/j.jcrc.2025.155016

Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study

2025

Journal Article

Respiratory syncytial virus infection in adult and paediatric patients admitted to intensive care in Australia: a nation-wide comparison with COVID-19

Tang, Yaodong, Zhao, Peinan, Cheng, Allen C., Ibrahim, Aaliya, Hassall, Jenna, Litton, Edward, Andersen, Christopher R., Liang, Cindy, Milford, Elissa M., Rose, Morgan, Plummer, Mark, Kong, Jing, Johnson, Kerry, Bihari, Shailesh, Chaba, Anis, Begum, Husna, Cruz, Sherene Magana, Ng, Sze, Trapani, Tony, Campbell, Lewis, Ramanan, Mahesh, McAllister, Richard, Chumbes, Jenipher, Erickson, Simon, Kol, Mark, Cheung, Winston, Udy, Andrew A. and Burrell, Aidan (2025). Respiratory syncytial virus infection in adult and paediatric patients admitted to intensive care in Australia: a nation-wide comparison with COVID-19. Critical Care and Resuscitation, 27 (2) 100113, 1-7. doi: 10.1016/j.ccrj.2025.100113

Respiratory syncytial virus infection in adult and paediatric patients admitted to intensive care in Australia: a nation-wide comparison with COVID-19

2025

Journal Article

Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trial

Niemelä, V. H., Reinikainen, M., Nielsen, N., Bass, F., Young, P., Lilja, G., Dankiewicz, J., Hammond, N., Hästbacka, J., Levin, H., Moseby‐Knappe, M., Saxena, M., Tiainen, M., Ceric, A., Holgersson, J., Kamp, C. B., Tirkkonen, J., Oksanen, T., Kaakinen, T., Bendel, S., Düring, J., Lybeck, A., Johnsson, J., Unden, J., Lundin, A., Kåhlin, J., Grip, J., Lotman, E., Romundstad, L. ... Skrifvars, M. B. (2025). Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (6) e70040, 1-11. doi: 10.1111/aas.70040

Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trial

2025

Journal Article

Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation

White, Kyle C., Costa-Pinto, Rahul, Blank, Sebastiaan, Whebell, Stephen, Quick, Lachlan, Luke, Stephen, Attokaran, Antony G., Garrett, Peter, Ramanan, Mahesh, Tabah, Alexis, Shekar, Kiran, Laupland, Kevin B., Kumar, Aashish, McCullough, James, Udy, Andrew, Eastwood, Glenn, Bellomo, Rinaldo, Chaba, Anis, the Queensland Critical Care Research Network (QCCRN), Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David ... Keogh, Sam (2025). Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation. Critical Care, 29 (1) 188, 1-10. doi: 10.1186/s13054-025-05401-y

Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation

2025

Journal Article

Tracking outcomes post intensive care: findings of a longitudinal observational study

Flaws, Dylan, Tronstad, Oystein, Fraser, John F., Lavana, Jayshree, Laupland, Kevin B., Ramanan, Mahesh, Tabah, Alexis and Patterson, Sue (2025). Tracking outcomes post intensive care: findings of a longitudinal observational study. Australian Critical Care, 38 (3) 101164, 1-8. doi: 10.1016/j.aucc.2024.101164

Tracking outcomes post intensive care: findings of a longitudinal observational study