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2018

Journal Article

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

Kojic, Marija, Gaik, Monika, Kiska, Bence, Salerno-Kochan, Anna, Hunt, Sarah, Tedoldi, Angelo, Mureev, Sergey, Jones, Alun, Whittle, Belinda, Genovesi, Laura A., Adolphe, Christelle, Brown, Darren L., Stow, Jennifer L., Alexandrov, Kirill, Sah, Pankaj, Glatt, Sebastian and Wainwright, Brandon J. (2018). Elongator mutation in mice induces neurodegeneration and ataxia-like behavior. Nature Communications, 9 (1) 3195, 3195. doi: 10.1038/s41467-018-05765-6

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

2018

Journal Article

TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kγ for suppression of inflammatory responses

Luo, Lin, Wall, Adam A., Tong, Samuel J., Hung, Yu, Xiao, Zhijian, Tarique, Abdullah A., Sly, Peter D., Fantino, Emmanuelle, Marzolo, María-Paz and Stow, Jennifer L. (2018). TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kγ for suppression of inflammatory responses. Cell Reports, 24 (11), 3033-3044. doi: 10.1016/j.celrep.2018.08.028

TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kγ for suppression of inflammatory responses

2018

Journal Article

Macropinosome formation by tent pole ruffling in macrophages

Condon, Nicholas D., Heddleston, John M., Chew, Teng-Leong, Luo, Lin, McPherson, Peter S., Ioannou, Maria S., Hodgson, Louis, Stow, Jennifer L. and Wall, Adam A. (2018). Macropinosome formation by tent pole ruffling in macrophages. The Journal of Cell Biology, 217 (11), 3873-3885. doi: 10.1083/jcb.201804137

Macropinosome formation by tent pole ruffling in macrophages

2018

Journal Article

Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion

Monteleone, Mercedes, Stanley, Amanda C., Chen, Kaiwen W., Brown, Darren L., Bezbradica, Jelena S., von Pein, Jessica B., Holley, Caroline L., Boucher, Dave, Shakespear, Melanie R., Kapetanovic, Ronan, Rolfes, Verena, Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2018). Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion. Cell Reports, 24 (6), 1425-1433. doi: 10.1016/j.celrep.2018.07.027

Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion

2018

Journal Article

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

Ramnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) ARTN e120274. doi: 10.1172/jci.insight.120274

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

2018

Journal Article

pTRAPs: Transmembrane adaptors in innate immune signaling

Curson, James E. B., Luo, Lin, Sweet, Matthew J. and Stow, Jennifer L. (2018). pTRAPs: Transmembrane adaptors in innate immune signaling. Journal of Leukocyte Biology, 103 (6), 1011-1019. doi: 10.1002/JLB.2RI1117-474R

pTRAPs: Transmembrane adaptors in innate immune signaling

2018

Journal Article

Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL

Schuelein, Ralf, Spencer, Hugh, Dagley, Laura F, Li, Peng Fei, Luo, Lin, Stow, Jennifer L, Abraham, Gilu, Naderer, Thomas, Gomez-Valero, Laura, Buchrieser, Carmen, Sugimoto, Chihiro, Yamagishi, Junya, Webb, Andrew I, Pasricha, Shivani and Hartland, Elizabeth L (2018). Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL. Cellular Microbiology, 20 (9) e12852, e12852. doi: 10.1111/cmi.12852

Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL

2018

Conference Publication

RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease

Ramnath, D., Irvine, K., Lukowski, S., Horsfall, L., Loh, K., Clouston, A., Patel, P., Iyer, A., Lampe, G., Stow, J., Schroder, K., Fairlie, D., Powell, J., Powell, E. and Sweet, M. (2018). RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease. International Liver Congress (ILC), Paris, France, 11-15 April, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/S0168-8278(18)31040-7

RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease

2018

Journal Article

Differential expression of genes and receptors in monocytes from patients with cystic fibrosis

Tarique, Abdullah A., Sly, Peter D., Cardenas, Diana G., Luo, Lin, Stow, Jennifer L., Bell, Scott C., Wainwright, Claire E. and Fantino, Emmanuelle (2018). Differential expression of genes and receptors in monocytes from patients with cystic fibrosis. Journal of Cystic Fibrosis, 18 (3), 342-348. doi: 10.1016/j.jcf.2018.07.012

Differential expression of genes and receptors in monocytes from patients with cystic fibrosis

2017

Journal Article

Salmonella effector SopD2 interferes with Rab34 function

Teo, Wei Xuan, Yang, Zhe, Kerr, Markus Charles, Luo, Lin, Guo, Zhong, Alexandrov, Kirill, Stow, Jenny Lea and Teasdale, Rohan David (2017). Salmonella effector SopD2 interferes with Rab34 function. Cell Biology International, 41 (4), 433-446. doi: 10.1002/cbin.10739

Salmonella effector SopD2 interferes with Rab34 function

2017

Journal Article

Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP

Luo, Lin, Tong, Samuel J., Wall, Adam A., Khromykh, Tatiana, Sweet, Matthew J. and Stow, Jennifer L. (2017). Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP. Immunology and Cell Biology, 95 (6), 564-570. doi: 10.1038/icb.2017.10

Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP

2017

Journal Article

Small GTPase Rab8a-recruited phosphatidylinositol 3-kinase γ regulates signaling and cytokine outputs from endosomal toll-like receptors

Wall, Adam A., Luo, Lin, Hung, Yu, Tong, Samuel J., Condon, Nicholas D., Blumenthal, Antje, Sweet, Matthew J. and Stow, Jennifer L. (2017). Small GTPase Rab8a-recruited phosphatidylinositol 3-kinase γ regulates signaling and cytokine outputs from endosomal toll-like receptors. Journal of Biological Chemistry, 292 (11), 4411-4422. doi: 10.1074/jbc.M116.766337

Small GTPase Rab8a-recruited phosphatidylinositol 3-kinase γ regulates signaling and cytokine outputs from endosomal toll-like receptors

2017

Book Chapter

Image-based analysis of phagocytosis: measuring engulfment and internalization

Condon, Nicholas D., Wall, Adam A., Yeo, Jeremy C., Hamilton, Nicholas A. and Stow, Jennifer L. (2017). Image-based analysis of phagocytosis: measuring engulfment and internalization. In Roberto Botelho (Ed.), Phagocytosis and phagosomes: methods and protocols (pp. 201-214) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-6581-6_13

Image-based analysis of phagocytosis: measuring engulfment and internalization

2016

Journal Article

Distinct roles for APPL1 and APPL2 in regulating toll-like receptor 4 signaling in macrophages

Yeo, Jeremy C., Wall, Adam A., Luo, Lin, Condon, Nicholas D. and Stow, Jennifer L. (2016). Distinct roles for APPL1 and APPL2 in regulating toll-like receptor 4 signaling in macrophages. Traffic, 17 (9), 1014-1026. doi: 10.1111/tra.12415

Distinct roles for APPL1 and APPL2 in regulating toll-like receptor 4 signaling in macrophages

2016

Journal Article

Small GTPases in trafficking - a family approach

Stow, Jennifer L. (2016). Small GTPases in trafficking - a family approach. Cellular Logistics, 6 (1), e1178036.1-e1178036.1. doi: 10.1080/21592799.2016.1178036

Small GTPases in trafficking - a family approach

2016

Journal Article

The cell surface environment for pathogen recognition and entry

Stow, Jennifer L. and Condon, Nicholas D. (2016). The cell surface environment for pathogen recognition and entry. Clinical and Translational Immunology, 5 (4) e71, e71.1-e71.7. doi: 10.1038/cti.2016.15

The cell surface environment for pathogen recognition and entry

2016

Journal Article

The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists

Chen, Kaiwen W., Bezbradica, Jelena S., Gross, Christina J., Wall, Adam A., Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2016). The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists. European Journal of Immunology, 46 (4), 1004-1010. doi: 10.1002/eji.201545943

The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists

2016

Journal Article

The binding of syndapin SH3 domain to dynamin proline-rich domain involves short and long distance elements

Luo, Lin, Xue, Jing, Kwan, Ann, Gamsjaeger, Roland, Wielens, Jerome, von Kleist, Lisa, Cubeddu, Liza, Guo, Zhong, Stow, Jennifer L., Parker, Michael W., Mackay, Joel P. and Robinson, Phillip J. (2016). The binding of syndapin SH3 domain to dynamin proline-rich domain involves short and long distance elements. Journal of Biological Chemistry, 291 (18), 9411-+. doi: 10.1074/jbc.M115.703108

The binding of syndapin SH3 domain to dynamin proline-rich domain involves short and long distance elements

2016

Journal Article

Sequential recruitment of Rab GTPases during early stages of phagocytosis

Yeo, Jeremy C., Wall, Adam A., Luo, Lin and Stow, Jennifer L. (2016). Sequential recruitment of Rab GTPases during early stages of phagocytosis. Cellular Logistics, 6 (1) e1140615, e1140615.1-e1140615.12. doi: 10.1080/21592799.2016.1140615

Sequential recruitment of Rab GTPases during early stages of phagocytosis

2016

Journal Article

RORα and 25-hydroxycholesterol crosstalk regulates lipid droplet homeostasis in macrophages

Tuong, Zewen Kelvin, Lau, Patrick, Du, Ximing, Condon, Nicholas D., Goode, Joel M., Oh, Tae Gyu, Yeo, Jeremy C., Muscat, George E. O. and Stow, Jennifer L. (2016). RORα and 25-hydroxycholesterol crosstalk regulates lipid droplet homeostasis in macrophages. PLoS ONE, 11 (1) e0147179, e0147179. doi: 10.1371/journal.pone.0147179

RORα and 25-hydroxycholesterol crosstalk regulates lipid droplet homeostasis in macrophages