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2013

Journal Article

RhoD participates in the regulation of cell-cycle progression and centrosome duplication

Kyrkou, A., Soufi, M., Bahtz, R., Ferguson, C., Bai, M., Parton, R. G., Hoffmann, I., Zerial, M., Fotsis, T. and Murphy, C. (2013). RhoD participates in the regulation of cell-cycle progression and centrosome duplication. Oncogene, 32 (14), 1831-1842. doi: 10.1038/onc.2012.195

RhoD participates in the regulation of cell-cycle progression and centrosome duplication

2013

Journal Article

Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation (vol 199, pg 425, 2012)

Joshi, Bharat, Bastiani, Michele, Strugnell, Scott S., Boscher, Cecile, Parton, Robert G. and Nabi, Ivan R. (2013). Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation (vol 199, pg 425, 2012). Journal of Cell Biology, 200 (5), 681-681. doi: 10.1083/jcb.2012070892005c

Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation (vol 199, pg 425, 2012)

2013

Journal Article

Characterisation of the adiponectin receptors: the non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface

Keshvari, Sahar, Rose, Felicity J., Charlton, Hayley K., Scheiber, Nicole L., Webster, Julie, Kim, Yu-Hee, Choaping Ng, Parton, Robert G. and Whitehead, Jonathan P. (2013). Characterisation of the adiponectin receptors: the non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface. Biochemical and Biophysical Research Communications, 432 (1), 28-33. doi: 10.1016/j.bbrc.2013.01.092

Characterisation of the adiponectin receptors: the non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface

2013

Journal Article

Caveolae as plasma membrane sensors, protectors and organizers

Parton, Robert G. and del Pozo, Miguel A. (2013). Caveolae as plasma membrane sensors, protectors and organizers. Nature Reviews Molecular Cell Biology, 14 (2), 98-112. doi: 10.1038/nrm3512

Caveolae as plasma membrane sensors, protectors and organizers

2013

Journal Article

The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments

Cortese, Katia, Howes, Mark T., Lundmark, Richard, Tagliatti, Erica, Bagnato, Paola, Petrelli, Annalisa, Bono, Maria, McMahon, Harvey T., Parton, Robert G. and Tacchetti, Carlo (2013). The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments. Molecular Biology of the Cell, 24 (2), 129-144. doi: 10.1091/mbc.E12-04-0282

The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments

2013

Journal Article

The RhoD to centrosomal duplication

Kyrkou, Athena, Soufi, Maria, Blatz, Ramona, Ferguson, Charles, Bai, Maria, Parton, Robert G., Hoffman, Ingrid, Zerial, Marino, Fotsis, Theodore and Murphy, Carol (2013). The RhoD to centrosomal duplication. Small GTPases, 4 (2), 116-122. doi: 10.4161/sgtp.23707

The RhoD to centrosomal duplication

2013

Journal Article

Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission

van der Hoeven, Dharini, Cho, Kwang-jin, Ma, Xiaoping, Chigurupati, Sravanthi, Parton, Robert G. and Hancock, John F. (2013). Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Molecular and Cellular Biology, 33 (2), 237-251. doi: 10.1128/MCB.00884-12

Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission

2012

Journal Article

Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins

Cho, Kwang-jin, Park, Jin-Hee, Piggott, Andrew M., Salim, Angela A., Gorfe, Alemaheyu A., Parton, Robert G., Capon, Robert J., Lacey, Ernest and Hancock, John F. (2012). Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins. Journal of Biological Chemistry, 287 (52), 43573-43584. doi: 10.1074/jbc.M112.424457

Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins

2012

Journal Article

Normalization of protein at different stages in SILAC subcellular proteomics affects functional analysis

Inder, Kerry L., Loo, Dorothy, Zheng, Yu Zi, Parton, Robert G., Foster, Leonard J. and Hill, Michelle M. (2012). Normalization of protein at different stages in SILAC subcellular proteomics affects functional analysis. Journal of Integrated OMICS, 2 (2), 114-122. doi: 10.5584/jiomics.v2i2.108

Normalization of protein at different stages in SILAC subcellular proteomics affects functional analysis

2012

Journal Article

Different characteristics and nucleotide binding properties of Inosine Monophosphate Dehydrogenase (IMPDH) isoforms

Thomas, Elaine C., Gunter, Jennifer H., Webster, Julie A., Schieber, Nicole L., Oorschot, Viola, Parton, Robert G. and Whitehead, Jonathan P. (2012). Different characteristics and nucleotide binding properties of Inosine Monophosphate Dehydrogenase (IMPDH) isoforms. PloS One, 7 (12) e51096, e51096.1-e51096.14. doi: 10.1371/journal.pone.0051096

Different characteristics and nucleotide binding properties of Inosine Monophosphate Dehydrogenase (IMPDH) isoforms

2012

Journal Article

Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation

Bharat, Joshi, Bastiani, Michele, Strugnell, Scott S., Boscher, Cecile, Parton, Robert G. and Nabi, Ivan R. (2012). Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation. Journal of Cell Biology, 199 (3), 425-435. doi: 10.1083/jcb.201207089

Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation

2012

Journal Article

Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model

Martin, Sally, Fernandez Rojo, Manuel A., Stanley, Amanda C., Bastiani, Michele, Okano, Satomi, Nixon, Susan J., Thomas, Gethin, Stow, Jennifer L. and Parton, Robert G. (2012). Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model. PLoS One, 7 (9) e46242, e46242. doi: 10.1371/journal.pone.0046242

Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model

2012

Journal Article

Caveolin-1 plays a critical role in the differentiation of monocytes into macrophages

Fu, Yi, Moore, Xiao-Lei, Lee, Man K. S., Fernández-Rojo, Manuel A., Parat, Marie-Odile, Parton, Robert G., Meikle, Peter J., Sviridov, Dmitri and Chin-Dusting, Jaye P. F. (2012). Caveolin-1 plays a critical role in the differentiation of monocytes into macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology, 32 (9), e117-e125. doi: 10.1161/ATVBAHA.112.254151

Caveolin-1 plays a critical role in the differentiation of monocytes into macrophages

2012

Journal Article

Constitutive formation of caveolae in a bacterium

Walser, Piers, Ariotti, Nicholas, Howes, Mark, Ferguson, Charles, Webb, Richard, Schwudke, Dominik, Leneva, Natalya, Cho, Kwang-Jin, Cooper, Leanne, Rae, James, Floetenmeyer, Matthias, Oorschot, Viola M. J., Skoglund, Ulf, Simons, Kai, Hancock, John F. and Parton, Robert G. (2012). Constitutive formation of caveolae in a bacterium. Cell, 150 (4), 752-763. doi: 10.1016/j.cell.2012.06.042

Constitutive formation of caveolae in a bacterium

2012

Journal Article

Co-regulation of cell polarization and migration by caveolar proteins PTRF/cavin-1 and caveolin-1

Hill, Michelle M., Daud, Noor Huda, Aung, Cho Sanda, Loo, Dorothy, Martin, Sally, Murphy, Samantha, Black, Debra M., Barry, Rachael, Simpson, Fiona, Liu, Libin, Pilch, Paul F, Hancock, John F., Marie-Odile Parat and Parton, Robert G. (2012). Co-regulation of cell polarization and migration by caveolar proteins PTRF/cavin-1 and caveolin-1. PLoS One, 7 (8) e43041, e43041.1-e43041.9. doi: 10.1371/journal.pone.0043041

Co-regulation of cell polarization and migration by caveolar proteins PTRF/cavin-1 and caveolin-1

2012

Journal Article

Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors

Kohnke, Monika, Schmitt, Steven, Ariotti, Nicholas, Piggott, Andrew, Parton, Robert G., Lacey, Ernest, Capon, Robert, Alexandrov, Kirill and Abankwa, Daniel (2012). Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors. Chemistry and Biology, 19 (7), 866-874. doi: 10.1016/j.chembiol.2012.05.019

Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors

2012

Journal Article

Structure-based reassessment of the caveolin signalling model: Do caveolae regulate signaling through caveolin-protein interactions

Collins, Brett, Davis, Melissa, Hancock, John F. and Parton, Robert G. (2012). Structure-based reassessment of the caveolin signalling model: Do caveolae regulate signaling through caveolin-protein interactions. Developmental Cell, 23 (1), 11-20. doi: 10.1016/j.devcel.2012.06.012

Structure-based reassessment of the caveolin signalling model: Do caveolae regulate signaling through caveolin-protein interactions

2012

Journal Article

SNX12 role in endosome membrane transport

Pons, Veronique, Ustunel, Cansel, Rolland, Corinne, Torti, Eleonora, Parton, Robert G. and Gruenberg, Jean (2012). SNX12 role in endosome membrane transport. PLoS One, 7 (6) e38949, e38949.1-e38949.8. doi: 10.1371/journal.pone.0038949

SNX12 role in endosome membrane transport

2012

Journal Article

Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration

Fernandez Rojo, Manuel Alejandro, Restall, Christina, Ferguson, Charles, Martel, Nick, Martin, Sally, Bosch, Marta, Kassan, Adam, Leong, Gary M., Martin, Sheree D., McGee, Sean L., Muscat, George E., Anderson, Robin L., Enrich, Carlos, Pol, Albert and Parton, Robert G. (2012). Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration. Hepatology, 55 (5), 1574-1584. doi: 10.1002/hep.24810

Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration

2012

Journal Article

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization

Moren, Björn, Shah, Claudio, Howes, Mark T., Schieber, Nicole L., McMahon, Harvey T., Parton, Robert G., Daumke, Oliver and Lundmark, Richard (2012). EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization. Molecular Biology of the Cell, 23 (7), 1316-1329. doi: 10.1091/mbc.E11-09-0787

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization