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2024 Journal Article Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endotheliumZhao, Jilai, Sormani, Laura, Jacquelin, Sebastien, Li, Haiming, Styke, Cassandra, Zhou, Chenhao, Beesley, Jonathan, Oon, Linus, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Dight, James, Hashemi, Ghazaleh, Shafiee, Abbas, Roy, Edwige, Patel, Jatin and Khosrotehrani, Kiarash (2024). Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endothelium. Angiogenesis, 27 (3), 1-16. doi: 10.1007/s10456-024-09927-7 |
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2023 Other Outputs Clonal progression in keratinocyte cancersWong, Ho Yi (2023). Clonal progression in keratinocyte cancers. PhD Thesis, Frazer Institute, The University of Queensland. doi: 10.14264/0d20403 |
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2023 Journal Article Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapyWong, Ho Yi, Lee, Ruby C., Chong, Sharene, Kapadia, Stuti, Freeman, Michael, Murigneux, Valentine, Brown, Susan, Soyer, H. Peter, Roy, Edwige and Khosrotehrani, Kiarash (2023). Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy. Science Advances, 9 (19) eadf2384, 1-13. doi: 10.1126/sciadv.adf2384 |
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2023 Conference Publication PDGFRA-expressing endovascular progenitors contribute to differentiated endothelium of aorta and woundsStyke, C., Kaur, S., Sim, S., Zhao, J., Shafiee, A., Zhou, C., Wong, H. and Khosrotehrani, K. (2023). PDGFRA-expressing endovascular progenitors contribute to differentiated endothelium of aorta and wounds. 1st International Societies for Investigative Dermatology Meeting, Tokyo, Japan, 10 - 13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.1476 |
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2023 Conference Publication Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapyWong, H., Lee, R., Chong, S., Kapadia, S., Murigneux, V., Freeman, M., Soyer, H., Roy, E. and Khosrotehrani, K. (2023). Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy. 1st International Societies for Investigative Dermatology Meeting, Tokyo, Japan, 12 - 13 May 2023. Oxford, United Kingdom: Elsevier. |
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2023 Conference Publication Epidermal somatic mutation is correlated with keratinocyte cancer burdenLee, Ruby, Wong, Ho Yi, Brown, Susan, Roy, Edwige, Soyer, Peter and Khosrotehrani, Kiarash (2023). Epidermal somatic mutation is correlated with keratinocyte cancer burden. HOBOKEN: WILEY. |
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2022 Conference Publication Variation in epidermal mutation burden after field treatment with topical 5-fluorouracilLee, R., Wong, H., Brown, S., Roy, E. and Khosrotehrani, K. (2022). Variation in epidermal mutation burden after field treatment with topical 5-fluorouracil. 51st Annual ESDR Meeting, Amsterdam, Netherlands, 28 September-1 October 2022. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2022.09.504 |
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2022 Conference Publication Epidermal ablation reduces keratinocyte cancer burden by lowering skin mutation loadWong, H., Lee, R., Roy, E., Kapadia, S., Murigneux, V., Chong, S., Freeman, M. and Khosrotehrani, K. (2022). Epidermal ablation reduces keratinocyte cancer burden by lowering skin mutation load. 51st Annual ESDR Meeting, Amsterdam, Netherlands, 28 September-1 October 2022. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2022.09.449 |
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2022 Journal Article Chemoprevention of cutaneous squamous cell carcinoma and its precursors in solid organ transplant recipients using topical sirolimus: a randomized, double-blind, placebo-controlled pilot trialChong, Sharene, Wong, Ho Yi, Althabteh, Ahmad, Cox, Charlotte, Stevenson, Paul H., Brown, Susan, Griffin, Anthony, Isbel, Nicole, Siller, Gregory, Soyer, H. Peter, Schaider, Helmut, Roy, Edwige, Campbell, Scott, Green, Adele C. and Khosrotehrani, Kiarash (2022). Chemoprevention of cutaneous squamous cell carcinoma and its precursors in solid organ transplant recipients using topical sirolimus: a randomized, double-blind, placebo-controlled pilot trial. Journal of the American Academy of Dermatology, 87 (5), 1163-1166. doi: 10.1016/j.jaad.2022.02.039 |
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2021 Journal Article Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitorsZhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9 |
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2021 Journal Article Whole-mount staining coupled to a UV-inducible basal cell carcinoma murine modelWong, Ho Yi, Khosrotehrani, Kiarash and Roy, Edwige (2021). Whole-mount staining coupled to a UV-inducible basal cell carcinoma murine model. STAR protocols, 2 (1) 100329, 100329. doi: 10.1016/j.xpro.2021.100329 |
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2020 Journal Article Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal ProgenitorsRoy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702 |
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2019 Journal Article Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cellsLukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102 |
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2019 Journal Article Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasisDonovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w |
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2019 Conference Publication Laser dermabrasion: a potential treatment for non-melanoma skin cancersWong, H., Roy, E., Kapadia, S., Murigneux, V., Chong, S. and Khosrotehrani, K. (2019). Laser dermabrasion: a potential treatment for non-melanoma skin cancers. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.567 |
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2019 Conference Publication Changing endothelial cell fate in wound healing through modulation of Sox9 to reduce scarringPatel, J., Hamilton, H., Kahler, S., Sim, S., Wong, H. and Khosrotehrani, K. (2019). Changing endothelial cell fate in wound healing through modulation of Sox9 to reduce scarring. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.628 |
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2019 Conference Publication Epidermal clonal expansion upon UV irradiation: consequences of the epidermal duality of proliferative behaviour on the skin carcinogenesisRoy, E., Wong, H. and Khosrotehrani, K. (2019). Epidermal clonal expansion upon UV irradiation: consequences of the epidermal duality of proliferative behaviour on the skin carcinogenesis. 49th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.570 |
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2018 Journal Article Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responsesLegrand, Julien M. D., Roy, Edwige, Baz, Batoul, Mukhopadhyay, Pamela, Wong, Ho Yi, Ram, Ramesh, Morahan, Grant, Walker, Graeme and Khosrotehrani, Kiarash (2018). Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responses. Journal of Allergy and Clinical Immunology, 142 (3), 981-984.e7. doi: 10.1016/j.jaci.2018.04.028 |
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2018 Journal Article A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradationChhabra, Y., Wong, H. Y., Nikolajsen, L. F., Steinocher, H., Papadopulos, A., Tunny, K. A., Meunier, F. A., Smith, A. G., Kragelund, B. B., Brooks, A. J. and Waters, M. J. (2018). A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation. Oncogene, 37 (4), 489-501. doi: 10.1038/onc.2017.352 |
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2018 Conference Publication Genome wide mapping identifies regulation of MAPKinase pathway as key genetic determinant of allergic contact dermatitisRoy, E., Legrand, J., Baz, B., Wong, H., Morahan, G., Walker, G. and Khosrotehrani, K. (2018). Genome wide mapping identifies regulation of MAPKinase pathway as key genetic determinant of allergic contact dermatitis. International Investigative Dermatology (IID) Meeting, Orlando, FL, United States, 16 - 19 May 2018. London, United Kingdom: Nature Publishing Group. |
