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2026 Journal Article Structure-activity relationship of steroidal-nitroxide hybrids: Dual-modulators of glucocorticoid receptor signalling and cellular redox stateSoltau, Carl P., Tay, Ban Qi, Martyn, Alexander P., Richard, Derek J., Adams, Mark N. and Bottle, Steven E. (2026). Structure-activity relationship of steroidal-nitroxide hybrids: Dual-modulators of glucocorticoid receptor signalling and cellular redox state. European Journal of Medicinal Chemistry, 307 118655, 118655-307. doi: 10.1016/j.ejmech.2026.118655 |
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2026 Journal Article Redox-active nitroxides enhance cisplatin efficacy against cervical cancerSoltau, Carl P., Sinha, Debottam, Patil, Lakshita P., Moseley, Philip M., Rayner, Cassie L., Barnett, Nigel L., Richard, Derek J., Bottle, Steven E., Frazer, Ian H. and Martyn, Alexander P. (2026). Redox-active nitroxides enhance cisplatin efficacy against cervical cancer. Redox Biology, 89 103989, 1-13. doi: 10.1016/j.redox.2025.103989 |
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2024 Journal Article Synthesis of anti-oxidant steroids by hybridisation with nitroxidesSoltau, Carl P., Weir, Naomi E., Martyn, Alexander P. and Bottle, Steven E. (2024). Synthesis of anti-oxidant steroids by hybridisation with nitroxides. Synthesis, 56 (21), 3289-3296. doi: 10.1055/a-2232-8240 |
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2023 Journal Article An exploration of small molecules that bind human single-stranded DNA binding protein 1Schuurs, Zachariah P., Martyn, Alexander P., Soltau, Carl P., Beard, Sam, Shah, Esha T., Adams, Mark N., Croft, Laura V., O'Byrne, Kenneth J., Richard, Derek J. and Gandhi, Neha S. (2023). An exploration of small molecules that bind human single-stranded DNA binding protein 1. Biology, 12 (11) 1405, 1-23. doi: 10.3390/biology12111405 |
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2023 Journal Article Preserving retinal structure and function with the novel nitroxide antioxidant, DCTEIORayner, Cassie L., Bottle, Steven E., Martyn, Alexander P. and Barnett, Nigel L. (2023). Preserving retinal structure and function with the novel nitroxide antioxidant, DCTEIO. Neurochemical Research, 48 (11), 3402-3419. doi: 10.1007/s11064-023-03978-w |
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2022 Journal Article Natural product-based PROteolysis TArgeting Chimeras (PROTACs)Liu, Miaomiao, Martyn, Alexander P. and Quinn, Ronald J. (2022). Natural product-based PROteolysis TArgeting Chimeras (PROTACs). Natural Product Reports, 39 (12), 2292-2307. doi: 10.1039/d2np00038e |
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2022 Journal Article Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matterSoltau, Carl P., Brown, Zac E., Brock, Aidan J., Martyn, Alexander P., Blinco, James P., Miljevic, Branka, McMurtrie, John C. and Bottle, Steven E. (2022). Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter. Chemical Communications, 58 (74), 10416-10419. doi: 10.1039/d2cc04024g |
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2020 Journal Article Synthesis of thioridazine-VLA-4 antagonist hybrids using N-propargyl northioridazine enantiomersMartyn, A. P., Willis, A. C. and Kelso, M. J. (2020). Synthesis of thioridazine-VLA-4 antagonist hybrids using N-propargyl northioridazine enantiomers. Synthetic Communications, 50 (18), 2796-2809. doi: 10.1080/00397911.2020.1785503 |
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2019 Journal Article Corrigendum to “Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens” [J. Struct. Biol. 204 (3) (2018) 396–405](S1047847718302818)(10.1016/j.jsb.2018.10.008)McGrath, Amy E., Martyn, Alexander P., Whittell, Louise R., Dawes, Fay E., El Salamouni, Nehad S., Beck, Jennifer L., Dixon, Nicholas E., Kelso, Michael J. and Oakley, Aaron J. (2019). Corrigendum to “Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens” [J. Struct. Biol. 204 (3) (2018) 396–405](S1047847718302818)(10.1016/j.jsb.2018.10.008). Journal of Structural Biology, 207 (2). doi: 10.1016/j.jsb.2019.05.003 |
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2018 Journal Article Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogensMcGrath, Amy E., Martyn, Alexander P., Whittell, Louise R., Dawes, Fay E., Beck, Jennifer L., Dixon, Nicholas E., Kelso, Michael J. and Oakley, Aaron J. (2018). Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. Journal of Structural Biology, 204 (3), 396-405. doi: 10.1016/j.jsb.2018.10.008 |
