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2025

Journal Article

TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation

Schultz, Thomas E., Mathmann, Carmen D., Domínguez Cadena, Leslie C., Muusse, Timothy W., Kim, Hyoyoung, Wells, James W., Ulett, Glen C., Hamerman, Jessica A., Brooks, Andrew J., Kobe, Bostjan, Sweet, Matthew J., Stacey, Katryn J. and Blumenthal, Antje (2025). TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation. EMBO Reports, 26 (10) 2250056, 2740-2766. doi: 10.1038/s44319-025-00444-2

TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation

2025

Journal Article

No added sugar: CCDC134 stabilizes ER chaperone Gp96 for TLR biogenesis

Blumenthal, Antje and Domínguez Cadena, Leslie C. (2025). No added sugar: CCDC134 stabilizes ER chaperone Gp96 for TLR biogenesis. Journal of Experimental Medicine, 222 (3) e20242285, 1-3. doi: 10.1084/jem.20242285

No added sugar: CCDC134 stabilizes ER chaperone Gp96 for TLR biogenesis

2024

Journal Article

Myddosomes in Toll-like receptor signaling-one to bind and rule them all

Mathmann, Carmen D., Schultz, Thomas E., Cadena, Leslie C. Dominguez and Blumenthal, Antje (2024). Myddosomes in Toll-like receptor signaling-one to bind and rule them all. Immunology and Cell Biology, 102 (9), 752-756. doi: 10.1111/imcb.12816

Myddosomes in Toll-like receptor signaling-one to bind and rule them all

2021

Journal Article

Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection

Domínguez Cadena, Leslie C., Schultz, Thomas E., Zamoshnikova, Alina, Donovan, Meg L., Mathmann, Carmen D., Yu, Chien-Hsiung, Mori, Giorgia, Stow, Jennifer L and Blumenthal, Antje (2021). Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection. Immunology and Cell Biology, 99 (10), 1067-1076. doi: 10.1111/imcb.12503

Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection