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2025

Journal Article

The bacterial cell envelope as a morphogenetic code for biofilm development

Qin, Jilong, Kinobe, Robert, Schaeffer, Patrick M. and Hong, Yaoqin (2025). The bacterial cell envelope as a morphogenetic code for biofilm development. Microbiology Australia, 46 (4), 227-230. doi: 10.1071/ma25064

The bacterial cell envelope as a morphogenetic code for biofilm development

2025

Journal Article

Not too rigid nor too wobbly: defining an optimal membrane fluidity range essential for biofilm formation in Escherichia coli

Hong, Yaoqin, Qin, Jilong and Totsika, Makrina (2025). Not too rigid nor too wobbly: defining an optimal membrane fluidity range essential for biofilm formation in Escherichia coli. mLife, 4 (4), 461-464. doi: 10.1002/mlf2.70024

Not too rigid nor too wobbly: defining an optimal membrane fluidity range essential for biofilm formation in Escherichia coli

2025

Journal Article

Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate

Hong, Yaoqin, Qin, Jilong, Doyle, Matthew Thomas and Reeves, Peter Richard (2025). Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate. Microbiology, 171 (1) 001530. doi: 10.1099/mic.0.001530

Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate

2025

Journal Article

Tolerance mechanisms in polysaccharide biosynthesis: implications for undecaprenol phosphate recycling in Escherichia coli and Shigella flexneri

Qin, Jilong, Hong, Yaoqin, Maczuga, Nicholas T., Morona, Renato and Totsika, Makrina (2025). Tolerance mechanisms in polysaccharide biosynthesis: implications for undecaprenol phosphate recycling in Escherichia coli and Shigella flexneri. PLOS Genetics, 21 (1) e1011591, e1011591-1. doi: 10.1371/journal.pgen.1011591

Tolerance mechanisms in polysaccharide biosynthesis: implications for undecaprenol phosphate recycling in Escherichia coli and Shigella flexneri

2024

Journal Article

Bacterial suppressor-of-copper-sensitivity proteins exhibit diverse thiol-disulfide oxidoreductase cellular functions

Hong, Yaoqin, Qin, Jilong, Mitchell, Lachlan, Paxman, Jason J., Heras, Begoña and Totsika, Makrina (2024). Bacterial suppressor-of-copper-sensitivity proteins exhibit diverse thiol-disulfide oxidoreductase cellular functions. iScience, 27 (12) 111392, 111392. doi: 10.1016/j.isci.2024.111392

Bacterial suppressor-of-copper-sensitivity proteins exhibit diverse thiol-disulfide oxidoreductase cellular functions

2024

Journal Article

Determining glycosyltransferase functional order via lethality due to accumulated O-antigen intermediates, exemplified with Shigella flexneri O-antigen biosynthesis

Qin, Jilong, Hong, Yaoqin and Totsika, Makrina (2024). Determining glycosyltransferase functional order via lethality due to accumulated O-antigen intermediates, exemplified with Shigella flexneri O-antigen biosynthesis. Applied and Environmental Microbiology, 90 (6) e02203-23, e0220323-6. doi: 10.1128/aem.02203-23

Determining glycosyltransferase functional order via lethality due to accumulated O-antigen intermediates, exemplified with Shigella flexneri O-antigen biosynthesis

2023

Journal Article

A conditional nature for the synthetical lethality between defects in lipid and peptidoglycan biosynthesis

Hong, Yaoqin, Qin, Jilong and Totsika, Makrina (2023). A conditional nature for the synthetical lethality between defects in lipid and peptidoglycan biosynthesis. Proceedings of the National Academy of Sciences, 120 (52) e2318882120. doi: 10.1073/pnas.2318882120

A conditional nature for the synthetical lethality between defects in lipid and peptidoglycan biosynthesis

2023

Journal Article

In vitro activities of oxazolidinone antibiotics alone and in combination with C-TEMPO against methicillin-resistant Staphylococcus aureus biofilms

Ndukwe, Audrey R. N., Qin, Jilong, Wiedbrauk, Sandra, Boase, Nathan R. B., Fairfull-Smith, Kathryn E. and Totsika, Makrina (2023). In vitro activities of oxazolidinone antibiotics alone and in combination with C-TEMPO against methicillin-resistant Staphylococcus aureus biofilms. Antibiotics, 12 (12) 1706, 1706. doi: 10.3390/antibiotics12121706

In vitro activities of oxazolidinone antibiotics alone and in combination with C-TEMPO against methicillin-resistant Staphylococcus aureus biofilms

2023

Journal Article

O antigen biogenesis sensitises Escherichia coli K-12 to bile salts, providing a plausible explanation for its evolutionary loss

Qin, Jilong, Hong, Yaoqin, Morona, Renato and Totsika, Makrina (2023). O antigen biogenesis sensitises Escherichia coli K-12 to bile salts, providing a plausible explanation for its evolutionary loss. PLOS Genetics, 19 (10) e1010996, e1010996. doi: 10.1371/journal.pgen.1010996

O antigen biogenesis sensitises Escherichia coli K-12 to bile salts, providing a plausible explanation for its evolutionary loss

2023

Journal Article

Preclinical evaluation of nitroxide-functionalised ciprofloxacin as a novel antibiofilm drug hybrid for urinary tract infections

Hawas, Sophia, Qin, Jilong, Wiedbrauk, Sandra, Fairfull-Smith, Kathryn and Totsika, Makrina (2023). Preclinical evaluation of nitroxide-functionalised ciprofloxacin as a novel antibiofilm drug hybrid for urinary tract infections. Antibiotics, 12 (10) 1479, 1479. doi: 10.3390/antibiotics12101479

Preclinical evaluation of nitroxide-functionalised ciprofloxacin as a novel antibiofilm drug hybrid for urinary tract infections

2023

Journal Article

Extensive diversity in Escherichia coli group 3 capsules is driven by recombination and plasmid transfer from multiple species

Hong, Yaoqin, Qin, Jilong, Forga, Xavier Bertran and Totsika, Makrina (2023). Extensive diversity in Escherichia coli group 3 capsules is driven by recombination and plasmid transfer from multiple species. Microbiology Spectrum, 11 (4) e01432-23, e0143223. doi: 10.1128/spectrum.01432-23

Extensive diversity in Escherichia coli group 3 capsules is driven by recombination and plasmid transfer from multiple species

2023

Journal Article

Simple and efficient synthesis of 3-aryl-2-oxazolidinone scaffolds enabling increased potency toward biofilms

Ndukwe, Audrey R. N., Hawas, Sophia, Qin, Jilong, Wiedbrauk, Sandra, Totsika, Makrina, Boase, Nathan R. B. and Fairfull-Smith, Kathryn E. (2023). Simple and efficient synthesis of 3-aryl-2-oxazolidinone scaffolds enabling increased potency toward biofilms. Molecular Pharmaceutics, 20 (7), 3484-3493. doi: 10.1021/acs.molpharmaceut.3c00095

Simple and efficient synthesis of 3-aryl-2-oxazolidinone scaffolds enabling increased potency toward biofilms

2022

Journal Article

Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics

Hong, Yaoqin, Qin, Jilong, Verderosa, Anthony D., Hawas, Sophia, Zhang, Bing, Blaskovich, Mark A. T., Cronan, John E. and Totsika, Makrina (2022). Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics. mSphere, 7 (3), e0011722. doi: 10.1128/msphere.00117-22

Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics

2022

Journal Article

Interdependence of Shigella flexneri O Antigen and Enterobacterial Common Antigen Biosynthetic Pathways

Maczuga, Nicholas, Tran, Elizabeth N. H., Qin, Jilong and Morona, Renato (2022). Interdependence of Shigella flexneri O Antigen and Enterobacterial Common Antigen Biosynthetic Pathways. Journal of Bacteriology, 204 (4) e00546-21, 4. doi: 10.1128/jb.00546-21

Interdependence of Shigella flexneri O Antigen and Enterobacterial Common Antigen Biosynthetic Pathways

2022

Journal Article

Development of 3D printed biodegradable mesh with antimicrobial properties for pelvic organ prolapse

Ren, Jiongyu, Murray, Rebecca, Wong, Cynthia S., Qin, Jilong, Chen, Michael, Totsika, Makrina, Riddell, Andrew D., Warwick, Andrea, Rukin, Nicholas and Woodruff, Maria A. (2022). Development of 3D printed biodegradable mesh with antimicrobial properties for pelvic organ prolapse. Polymers, 14 (4) 763, 763. doi: 10.3390/polym14040763

Development of 3D printed biodegradable mesh with antimicrobial properties for pelvic organ prolapse

2014

Journal Article

UV-driven microvalve based on a micro–nano TiO<sub>2</sub>/SiO<sub>2</sub>composite surface for microscale flow control

Guo, Ting, Meng, Tao, Li, Wei, Qin, Jilong, Tong, Zhiping, Zhang, Qing and Li, Xueru (2014). UV-driven microvalve based on a micro–nano TiO2/SiO2composite surface for microscale flow control. Nanotechnology, 25 (12) 125301, 125301. doi: 10.1088/0957-4484/25/12/125301

UV-driven microvalve based on a micro–nano TiO<sub>2</sub>/SiO<sub>2</sub>composite surface for microscale flow control