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2017

Journal Article

Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy

Nosrati, Adi, Tsai, Katy K., Goldinger, Simone M., Tumeh, Paul, Grimes, Barbara, Loo, Kimberly, Algazi, Alain P., Thi Dan Linh Nguyen-Kim, , Levesque, Mitchell, Dummer, Reinhard, Hamid, Omid and Daud, Adil (2017). Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy. British Journal of Cancer, 116 (9), 1141-1147. doi: 10.1038/bjc.2017.70

Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy

2017

Journal Article

Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

Zimmer, Lisa, Apuri, Susmitha, Eroglu, Zeynep, Kottschade, Lisa A., Forschner, Andrea, Gutzmer, Ralf, Schlaak, Max, Heinzerling, Lucie, Krackhardt, Angela M., Loquai, Carmen, Markovic, Svetomir N., Joseph, Richard W., Markey, Kelly, Utikal, Jochen S., Weishaupt, Carsten, Goldinger, Simone M., Sondak, Vernon K., Zager, Jonathan S., Schadendorf, Dirk and Khushalani, Nikhil I. (2017). Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma. European Journal of Cancer, 75, 47-55. doi: 10.1016/j.ejca.2017.01.009

Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

2017

Journal Article

A review of serious adverse effects under treatment with checkpoint inhibitors

Heinzerling, Lucie and Goldinger, Simone M. (2017). A review of serious adverse effects under treatment with checkpoint inhibitors. Current Opinion in Oncology, 29 (2), 136-144. doi: 10.1097/CCO.0000000000000358

A review of serious adverse effects under treatment with checkpoint inhibitors

2017

Journal Article

Developments in targeted therapy in melanoma

Amann, V. C., Ramelyte, E., Thurneysen, S., Pitocco, R., Bentele-Jaberg, N., Goldinger, S. M., Dummer, R. and Mangana, J. (2017). Developments in targeted therapy in melanoma. Ejso, 43 (3), 581-593. doi: 10.1016/j.ejso.2016.10.014

Developments in targeted therapy in melanoma

2017

Journal Article

Critical aspects to achieve a high-quality melanoma clinic

Dummer, Reinhard, Ramelyte, Egle, Levesque, Mitch, Goldinger, Simone M. and Braun, Ralph P. (2017). Critical aspects to achieve a high-quality melanoma clinic. Current Opinion in Oncology, 29 (2), 145-150. doi: 10.1097/CCO.0000000000000357

Critical aspects to achieve a high-quality melanoma clinic

2016

Journal Article

Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?

Diem, Stefan, Keller, Fabienne, Ruesch, Reinhard, Maillard, Samia A., Speiser, Daniel E., Dummer, Reinhard, Siano, Marco, Urner-Bloch, Ursula, Goldinger, Simone M. and Flatz, Lukas (2016). Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?. Journal of Immunotherapy, 39 (9), 379-382. doi: 10.1097/CJI.0000000000000143

Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?

2016

Journal Article

An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel

Thurneysen, S., Cheng, P. F., Nagel, H. W., Kunz, M., Jaberg-Bentele, N., Nageli, M., Ziegler, M., Guenova, E., Goldinger, S. M., Mangana, J., Levesque, M. P. and Dummer, R. (2016). An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel. British Journal of Dermatology, 175 (5), 966-978. doi: 10.1111/bjd.14727

An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel

2016

Journal Article

MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects

Urner-Bloch, U., Urner, M., Jaberg-Bentele, N., Frauchiger, A. L., Dummer, R. and Goldinger, S. M. (2016). MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects. European Journal of Cancer, 65, 130-138. doi: 10.1016/j.ejca.2016.06.018

MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects

2016

Journal Article

Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy

Goldinger, Simone M., Stieger, Pascale, Meier, Barbara, Micaletto, Sara, Contassot, Emmanuel, French, Lars E. and Dummer, Reinhard (2016). Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy. Clinical Cancer Research, 22 (16), 4023-4029. doi: 10.1158/1078-0432.CCR-15-2872

Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy

2016

Journal Article

Efficacy and Safety of AP0866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial

Goldinger, Simone M., Bischof, Sharon Gobbi, Fink-Puches, Regina, Klemke, Claus-Detlev, Dreno, Brigitte, Bagot, Martine and Dummer, Reinhard (2016). Efficacy and Safety of AP0866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial. Jama Dermatology, 152 (7), 837-839. doi: 10.1001/jamadermatol.2016.0401

Efficacy and Safety of AP0866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial

2016

Journal Article

Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy

Hofmann, Lars, Forschner, Andrea, Loquai, Carmen, Goldinger, Simone M., Zimmer, Lisa, Ugurel, Selma, Schmidgen, Maria I., Gutzmer, Ralf, Utikal, Jochen S., Goeppner, Daniela, Hassel, Jessica C., Meier, Friedegund, Tietze, Julia K., Thomas, Ioannis, Weishaupt, Carsten, Leverkus, Martin, Wahl, Renate, Dietrich, Ursula, Garbe, Claus, Kirchberger, Michael C., Eigentler, Thomas, Berking, Carola, Gesierich, Anja, Krackhardt, Angela M., Schadendorf, Dirk, Schuler, Gerold, Dummer, Reinhard and Heinzerling, Lucie M. (2016). Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy. European Journal of Cancer, 60, 190-209. doi: 10.1016/j.ejca.2016.02.025

Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy

2016

Journal Article

Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy

Zimmer, Lisa, Goldinger, Simone M., Hofmann, Lars, Loquai, Carmen, Ugurel, Selma, Thomas, Ioannis, Schmidgen, Maria I., Gutzmer, Ralf, Utikal, Jochen S., Goeppner, Daniela, Hassel, Jessica C., Meier, Friedegund, Tietze, Julia K., Forschner, Andrea, Weishaupt, Carsten, Leverkus, Martin, Wahl, Renate, Dietrich, Ursula, Garbe, Claus, Kirchberger, Michael C., Eigentler, Thomas, Berking, Carola, Gesierich, Anja, Krackhardt, Angela M., Schadendorf, Dirk, Schuler, Gerold, Dummer, Reinhard and Heinzerling, Lucie M. (2016). Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy. European Journal of Cancer, 60, 210-225. doi: 10.1016/j.ejca.2016.02.024

Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy

2016

Journal Article

Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation

Henning, Benjamin, Stieger, Pascale, Kamarachev, Jivko, Dummer, Reinhard and Goldinger, Simone M. (2016). Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation. Melanoma Research, 26 (3), 304-307. doi: 10.1097/CMR.0000000000000248

Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation

2016

Journal Article

Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status

Frauchiger, A. L., Mangana, J., Rechsteiner, M., Moch, H., Seifert, B., Braun, R. P., Dummer, R. and Goldinger, S. M. (2016). Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status. British Journal of Dermatology, 174 (4), 823-830. doi: 10.1111/bjd.14347

Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status

2016

Journal Article

Treatment of melanoma brain metastases

Goldinger, Simone M., Panje, Cedric and Nathan, Paul (2016). Treatment of melanoma brain metastases. Current Opinion in Oncology, 28 (2), 159-165. doi: 10.1097/CCO.0000000000000270

Treatment of melanoma brain metastases

2016

Journal Article

Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study

Kunz, M., Urosevic-Maiwald, M., Goldinger, S. M., Frauchiger, A. L., Dreier, J., Belloni, B., Mangana, J., Jenni, D., Dippel, M., Cozzio, A., Guenova, E., Kamarachev, J., French, L. E. and Dummer, R. (2016). Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study. Journal of the European Academy of Dermatology and Venereology, 30 (2), 293-298. doi: 10.1111/jdv.13444

Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study

2016

Journal Article

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8<SUP>+</SUP> T-cell responses in melanoma patients (vol 42, pg 3049, 2012)

Goldinger, Simone M., Dummer, Reinhard, Baumgaertner, Petra, Mihic-Probst, Daniela, Schwarz, Katrin, Hammann-Haenni, Anya, Willers, Joerg, Geldhof, Christine, Prior, John O., Kuendig, Thomas M., Michielin, Olivier, Bachmann, Martin F. and Speiser, Daniel E. (2016). Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8+ T-cell responses in melanoma patients (vol 42, pg 3049, 2012). European Journal of Immunology, 46 (2), 493-493. doi: 10.1002/eji.201670027

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8<SUP>+</SUP> T-cell responses in melanoma patients (vol 42, pg 3049, 2012)

2016

Journal Article

Noncutaneous Melanomas: A Single-Center Analysis

Del Prete, Valerio, Chaloupka, Karla, Holzmann, David, Fink, Daniel, Levesque, Mitchell, Dummer, Reinhard and Goldinger, Simone M. (2016). Noncutaneous Melanomas: A Single-Center Analysis. Dermatology, 232 (1), 22-29. doi: 10.1159/000441444

Noncutaneous Melanomas: A Single-Center Analysis

2015

Journal Article

Acquired <i>BRAF</i> inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms

Johnson, Douglas B., Menzies, Alexander M., Zimmer, Lisa, Eroglu, Zeynep, Ye, Fei, Zhao, Shilin, Rizos, Helen, Sucker, Antje, Scolyer, Richard A., Gutzmer, Ralf, Gogas, Helen, Kefford, Richard F., Thompson, John F., Becker, Juergen C., Berking, Carola, Egberts, Friederike, Loquai, Carmen, Goldinger, Simone M., Pupo, Gulietta M., Hugo, Willy, Kong, Xiangju, Garraway, Levi A., Sosman, Jeffrey A., Ribas, Antoni, Lo, Roger S., Long, Georgina V. and Schadendorf, Dirk (2015). Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms. European Journal of Cancer, 51 (18), 2792-2799. doi: 10.1016/j.ejca.2015.08.022

Acquired <i>BRAF</i> inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms

2015

Journal Article

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

Van Allen, Eliezer M., Miao, Diana, Schilling, Bastian, Shukla, Sachet A., Blank, Christian, Zimmer, Lisa, Sucker, Antje, Hillen, Uwe, Foppen, Marnix H. Geukes, Goldinger, Simone M., Utikal, Jochen, Hassel, Jessica C., Weide, Benjamin, Kaehler, Katharina C., Loquai, Carmen, Mohr, Peter, Gutzmer, Ralf, Dummer, Reinhard, Gabriel, Stacey, Wu, Catherine J., Schadendorf, Dirk and Garraway, Levi A. (2015). Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science, 350 (6257), 207-211. doi: 10.1126/science.aad0095

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma