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2025 Journal Article A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infectionYeap, Hui Wen, Goh, Ghin Ray, Rosli, Safwah Nasuha, Pung, Hai Shin, Giogha, Cristina, Eng, Vik Ven, Pearson, Jaclyn S., Hartland, Elizabeth L. and Chen, Kaiwen W. (2025). A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection. The EMBO Journal, 44 (9), 2424-2445. doi: 10.1038/s44318-025-00412-5 |
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2023 Journal Article A common human MLKL polymorphism confers resistance to negative regulation by phosphorylationGarnish, Sarah E., Martin, Katherine R., Kauppi, Maria, Jackson, Victoria E., Ambrose, Rebecca, Eng, Vik Ven, Chiou, Shene, Meng, Yanxiang, Frank, Daniel, Crutchfield, Emma C. Tovey, Patel, Komal M., Jacobsen, Annette V., Atkin-Smith, Georgia K., Di Rago, Ladina, Doerflinger, Marcel, Horne, Christopher R., Hall, Cathrine, Young, Samuel N., Cook, Matthew, Athanasopoulos, Vicki, Vinuesa, Carola G., Lawlor, Kate E., Wicks, Ian P., Ebert, Gregor, Ng, Ashley P., Slade, Charlotte A., Pearson, Jaclyn S., Samson, Andre L., Silke, John ... Hildebrand, Joanne M. (2023). A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation. Nature Communications, 14 (1) 6046, 1-17. doi: 10.1038/s41467-023-41724-6 |
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2022 Journal Article Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell deathFrank, Daniel, Garnish, Sarah E., Sandow, Jarrod J., Weir, Ashley, Liu, Lin, Clayer, Elise, Meza, Lizeth, Rashidi, Maryam, Cobbold, Simon A., Scutts, Simon R., Doerflinger, Marcel, Anderton, Holly, Lawlor, Kate E., Lalaoui, Najoua, Kueh, Andrew J., Eng, Vik Ven, Ambrose, Rebecca L., Herold, Marco J., Samson, Andre L., Feltham, Rebecca, Murphy, James M., Ebert, Gregor, Pearson, Jaclyn S. and Vince, James E. (2022). Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death. iScience, 25 (7) 104632, 1-29. doi: 10.1016/j.isci.2022.104632 |
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2021 Journal Article In vivo studies on Citrobacter rodentium and host cell death pathwaysEng, Vik Ven and Pearson, Jaclyn S. (2021). In vivo studies on Citrobacter rodentium and host cell death pathways. Current Opinion in Microbiology, 64, 60-67. doi: 10.1016/j.mib.2021.09.005 |
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2021 Journal Article An acetate‐yielding diet imprints an immune and anti‐microbial programme against enteric infectionYap, Yu Anne, McLeod, Keiran H., McKenzie, Craig I., Gavin, Patrick G., Davalos‐Salas, Mercedes, Richards, James L., Moore, Robert J., Lockett, Trevor J., Clarke, Julie M., Eng, Vik Ven, Pearson, Jaclyn S., Hamilton‐Williams, Emma E., Mackay, Charles R. and Mariño, Eliana (2021). An acetate‐yielding diet imprints an immune and anti‐microbial programme against enteric infection. Clinical and Translational Immunology, 10 (1) e1233, e1233. doi: 10.1002/cti2.1233 |
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2021 Journal Article The diverse roles of RIP kinases in host-pathogen interactionsEng, Vik Ven, Wemyss, Madeleine A. and Pearson, Jaclyn S. (2021). The diverse roles of RIP kinases in host-pathogen interactions. Seminars in Cell and Developmental Biology, 109, 125-143. doi: 10.1016/j.semcdb.2020.08.005 |