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2026

Journal Article

Generation of two CASK patient-derived human induced pluripotent stem cell lines to study CASK-related disorders

Veleva, Desi, Chowdhury, Mahfuz, Morrison, Sean D., Prowse, Andrew, Vadlamudi, Lata, Thor, Stefan, Wolvetang, Ernst J. and Pars, Selin (2026). Generation of two CASK patient-derived human induced pluripotent stem cell lines to study CASK-related disorders. Stem Cell Research, 95 104051, 1-5. doi: 10.1016/j.scr.2026.104051

Generation of two CASK patient-derived human induced pluripotent stem cell lines to study CASK-related disorders

2024

Journal Article

Valproic acid-induced teratogenicity is driven by senescence and prevented by Rapamycin in human spinal cord and animal models

Pietrogrande, Giovanni, Shaker, Mohammed R., Stednitz, Sarah J., Soheilmoghaddam, Farhad, Aguado, Julio, Morrison, Sean D., Zambrano, Samuel, Tabassum, Tahmina, Javed, Ibrahim, Cooper-White, Justin, Davis, Thomas P., O’Brien, Terence J., Scott, Ethan K. and Wolvetang, Ernst J. (2024). Valproic acid-induced teratogenicity is driven by senescence and prevented by Rapamycin in human spinal cord and animal models. Molecular Psychiatry, 30 (3) 200, 1-13. doi: 10.1038/s41380-024-02732-0

Valproic acid-induced teratogenicity is driven by senescence and prevented by Rapamycin in human spinal cord and animal models

2024

Journal Article

Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2

Shaker, Mohammed R., Slonchak, Andrii, Al-Mhanawi, Bahaa, Morrison, Sean D., Sng, Julian D.J., Cooper-White, Justin, Khromykh, Alexander A. and Wolvetang, Ernst J. (2024). Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2. Science Advances, 10 (23) eadj4735, 1-23. doi: 10.1126/sciadv.adj4735

Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2

2023

Journal Article

Protocol for generating embedding-free brain organoids enriched with oligodendrocytes

Al-mhanawi, Bahaa, Marti, Marta Boira, Morrison, Sean D., Gupta, Pallavi, Alani, Maath, Noakes, Peter G., Wolvetang, Ernst J. and Shaker, Mohammed R. (2023). Protocol for generating embedding-free brain organoids enriched with oligodendrocytes. STAR Protocols, 4 (4) 102725, 1-18. doi: 10.1016/j.xpro.2023.102725

Protocol for generating embedding-free brain organoids enriched with oligodendrocytes

2023

Journal Article

Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2

Shaker, Mohammed R., Slonchak, Andrii, Al-mhanawi, Bahaa, Morrison, Sean D., Sng, Julian D. J., Cooper-White, Justin, Khromykh, Alexander A. and Wolvetang, Ernst J. (2023). Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2. bioRxiv, 10 (23) eadj4735, eadj4735. doi: 10.1101/2023.06.12.544552

Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2