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2015

Conference Publication

Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration

Kumar, Vinod, Lee, John, Noakes, Peter and Woodruff, Trent (2015). Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration. 8th International Conference on Complement Therapeutics, Chania, Crete, Greece, 1-6 January 2015.

Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration

2014

Journal Article

Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood

Mantovani, S., Gordon, R., Macmaw, J. K., Plfluger, C. M., Henderson, R. D., Noakes, P. G., McCombe, P. A. and Woodruff, T. M. (2014). Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood. Journal of Neuroimmunology, 276 (1-2), 213-218. doi: 10.1016/j.jneuroim.2014.09.005

Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood

2014

Journal Article

Role for terminal complement activation in amyotrophic lateral sclerosis disease progression

Woodruff, Trent M., Lee, John D. and Noakes, Peter G. (2014). Role for terminal complement activation in amyotrophic lateral sclerosis disease progression. Proceeding of the National Academy of Sciences of the United States of America, 111 (1), E3-E4. doi: 10.1073/pnas.1321248111

Role for terminal complement activation in amyotrophic lateral sclerosis disease progression

2013

Journal Article

A method for the three-dimensional reconstruction of Neurobiotin(TM)-filled neurons and the location of their synaptic inputs

Fogarty, Matthew J., Hammond, Luke A., Kanjhan, Refik, Bellingham, Mark C. and Noakes, Peter G. (2013). A method for the three-dimensional reconstruction of Neurobiotin(TM)-filled neurons and the location of their synaptic inputs. Frontiers in Neural Circuits, 7 (OCT) 153, 1-18. doi: 10.3389/fncir.2013.00153

A method for the three-dimensional reconstruction of Neurobiotin(TM)-filled neurons and the location of their synaptic inputs

2013

Journal Article

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

Lee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

2013

Journal Article

Identification of RNA bound to the TDP-43 ribonucleoprotein complex in the adult mouse brain

Narayanan, Ramesh K., Mangelsdorf, Marie, Panwar, Ajay, Butler, Tim J., Noakes, Peter G. and Wallace, Robyn H. (2013). Identification of RNA bound to the TDP-43 ribonucleoprotein complex in the adult mouse brain. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (4), 252-260. doi: 10.3109/21678421.2012.734520

Identification of RNA bound to the TDP-43 ribonucleoprotein complex in the adult mouse brain

2013

Journal Article

Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development

Fogarty, Matthew J., Smallcombe, Karen L., Yanagawa, Yuchio, Obata, Kunihiko, Bellingham, Mark C. and Noakes, Peter G. (2013). Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development. PLoS One, 8 (2) e56257, e56257. doi: 10.1371/journal.pone.0056257

Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development

2013

Conference Publication

A method for the three-dimensional reconstruction and quantification of dendrites and synaptic inputs in Neurobiotin(TM)-filled glycine- and GABAA receptor clustering deficient neurons post functional assessment

Fogarty, M. J., Hammond, L. A., Kanjhan, R., Bellingham, M. C. and Noakes, P. G. (2013). A method for the three-dimensional reconstruction and quantification of dendrites and synaptic inputs in Neurobiotin(TM)-filled glycine- and GABAA receptor clustering deficient neurons post functional assessment. Neuroscience 2013: 43rd Annual Meeting of the Society for Neuroscience, San Diago, CA, United States, 9-13 November, 2012.

A method for the three-dimensional reconstruction and quantification of dendrites and synaptic inputs in Neurobiotin(TM)-filled glycine- and GABAA receptor clustering deficient neurons post functional assessment

2012

Journal Article

Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation

Ngo, Shyuan T., Cole, Rebecca N., Sunn, Nana, Phillips, William D. and Noakes, Peter G. (2012). Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation. Journal of Cell Science, 125 (6), 1531-1543. doi: 10.1242/jcs.095109

Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation

2012

Book Chapter

Innate immunity in ALS

Lee, John D., Lee, Jia Y., Taylor, Stephen M., Noakes, Peter G. and Woodruff, Trent M. (2012). Innate immunity in ALS. Amyotrophic lateral sclerosis. (pp. 393-412) edited by Martin H. Maurer. Croatia: InTech - Open Access Publisher. doi: 10.5772/30341

Innate immunity in ALS

2011

Journal Article

Muscle Specific Kinase: Organiser of synaptic membrane domains

Ghazanfari, Nazanin, Fernandez, Kristine J., Murata, Yui, Morsch, Marco, Ngo, Shyuan T., Reddel, Stephen W., Noakes, Peter G. and Phillips, William D. (2011). Muscle Specific Kinase: Organiser of synaptic membrane domains. The International Journal of Biochemistry and Cell Biology, 43 (3), 295-298. doi: 10.1016/j.biocel.2010.10.008

Muscle Specific Kinase: Organiser of synaptic membrane domains

2010

Journal Article

The two-pore domain K+ channel TASK-1 is closely associated with brain barriers and meninges

Kanjhan, Refik, Pow, David V., Noakes, Peter G. and Bellingham, Mark C. (2010). The two-pore domain K+ channel TASK-1 is closely associated with brain barriers and meninges. Journal of Molecular Histology, 41 (6), 315-323. doi: 10.1007/s10735-010-9293-3

The two-pore domain K+ channel TASK-1 is closely associated with brain barriers and meninges

2010

Journal Article

Myocardial deletion of Smad4 using a novel alpha skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract

Azhar, M, Wang, PY, Frugier, T, Koishi, K, Deng, CX, Noakes, PG and McLennan, IS (2010). Myocardial deletion of Smad4 using a novel alpha skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract. International Journal of Biological Sciences, 6 (6), 546-555. doi: 10.7150/ijbs.6.546

Myocardial deletion of Smad4 using a novel alpha skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract

2010

Journal Article

The role of the complement system and the activation fragment C5a in the central nervous system

Woodruff, T. M., Ager, R. R., Tenner, A. J., Noakes, P. G. and Taylor, S. M. (2010). The role of the complement system and the activation fragment C5a in the central nervous system. Neuromolecular Medecine, 12 (2), 179-192. doi: 10.1007/s12017-009-8085-y

The role of the complement system and the activation fragment C5a in the central nervous system

2010

Journal Article

Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists

Muttenthaler, Marcus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J. and Alewood, Paul F. (2010). Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists. Journal of the American Chemical Society, 132 (10), 3514-3522. doi: 10.1021/ja910602h

Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists

2010

Journal Article

In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2

Barclay, Johanna L., Kerr, Linda M., Arthur, Leela, Rowland, Jennifer E., Nelson, Caroline N., Ishikawa, Mayumi, d'Aniello, Elisabetta M., White, Mary, Noakes, Peter G. and Waters, Michael J. (2010). In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2. Molecular Endocrinology, 24 (1), 204-217. doi: 10.1210/me.2009-0233

In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2

2010

Conference Publication

Dysregulation of the complement system in neurodegenerative disease

Woodruff, T. M., Lee, J. D., Taylor, S. M. and Noakes, P. G. (2010). Dysregulation of the complement system in neurodegenerative disease. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.215

Dysregulation of the complement system in neurodegenerative disease

2009

Conference Publication

Neuregulin potentiates agrin-induced acetylcholine receptor clustering via a non-transcriptional mechanism in skeletal muscles

Ngo, S.T., Cole, R.N., Sunn, N., Phillips, W.D. and Noakes, P.G. (2009). Neuregulin potentiates agrin-induced acetylcholine receptor clustering via a non-transcriptional mechanism in skeletal muscles. 9th Hunter Valley Cellular Biology Meeting, Hunter Valley, NSW, Australia, 23-25 September 2009.

Neuregulin potentiates agrin-induced acetylcholine receptor clustering via a non-transcriptional mechanism in skeletal muscles

2009

Conference Publication

Neuregulin Modulates Acetylcholine Receptor Clustering via Non-transcriptional Mechanisms

Shyuan, N., Cole, R. N., Sunn, N., Phillips, W. D. and Noakes, P. G. (2009). Neuregulin Modulates Acetylcholine Receptor Clustering via Non-transcriptional Mechanisms. ANS 29th Annual meeting 2009, Canberra, ACT, 27 - 30 January, 2009. Online: Australian Neuroscience Society.

Neuregulin Modulates Acetylcholine Receptor Clustering via Non-transcriptional Mechanisms

2009

Journal Article

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres

Crane, James W., Baiquni, Gilang P., Sullivan, Robert K. P., Lee, John D, Sah, Pankaj, Taylor, Stephen M, Noakes, Peter G. and Woodruff, Trent (2009). The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres. Journal of Neuroinflammation, 6 (34) 34, 34.1-34.10. doi: 10.1186/1742-2094-6-34

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres