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2026

Journal Article

Antigen-detected NMR for minimal epitope engineering and structure-guided selection of a NaV1.7-selective nanobody

Liu, Junyu, Chen, Wanlin, Cristofori-Armstrong, Ben, Crawford, Theo, Chen, Kai-En, Xie, Peng, Chan, Rainbow Wing Bo, Zhu, Yifei, Golder, Mimi, Pereira Schmidt, Anneka, Naughton, Jennifer D., Condon, Nicholas D., Andersson, Asa, Dehkhoda, Farhad, McMahon, Kirsten L., Klasfauseweh, Tabea, Thapa, Ashvriya, Tran, Hue, Tran, Poanna, Jami, Sina, Ragnarsson, Lotten, Furness, Sebastian G. B., Deuis, Jennifer R., Collins, Brett M., Tham, Wai-Hong, Prasadam, Indira, Vetter, Irina and Mobli, Mehdi (2026). Antigen-detected NMR for minimal epitope engineering and structure-guided selection of a NaV1.7-selective nanobody. Advanced Science e77611, e77611. doi: 10.1002/advs.77611

Antigen-detected NMR for minimal epitope engineering and structure-guided selection of a NaV1.7-selective nanobody

2026

Journal Article

The Excelsatoxin A-receptor TMEM233 modulates Nav1.8

Oprita, George, Meyer, Marvin J. A., Rudolf, Daniel, Stein, Ines C. A. Pombeiro, Deuis, Jennifer R., Tran, Hue N. T., Durek, Thomas, Tabea, Klasfauseweh, Sina, Jami, Waxman, Stephen G., Dib-Hajj, Sulayman D., Babes, Alexandru, Vetter, Irina and Leffler, Andreas (2026). The Excelsatoxin A-receptor TMEM233 modulates Nav1.8. Faseb Journal, 40 (6) e71706. doi: 10.1096/fj.202600787R

The Excelsatoxin A-receptor TMEM233 modulates Nav1.8

2025

Other Outputs

Structure and function of ion channels in pain pathways: a toxin perspective

Klasfauseweh, Tabea (2025). Structure and function of ion channels in pain pathways: a toxin perspective. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/977b6c5

Structure and function of ion channels in pain pathways: a toxin perspective

2024

Journal Article

The ‘dispanins’ and related proteins in physiology and neurological disease

Deuis, Jennifer R., Klasfauseweh, Tabea, Walker, Lucinda and Vetter, Irina (2024). The ‘dispanins’ and related proteins in physiology and neurological disease. Trends in Neurosciences, 47 (8), 622-634. doi: 10.1016/j.tins.2024.06.004

The ‘dispanins’ and related proteins in physiology and neurological disease

2023

Journal Article

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

Jami, Sina, Deuis, Jennifer R., Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L., Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R., Ju, Robert J., Robinson, Samuel D., Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L., Tran, Hue N. T., Chin, Yanni K.-Y., Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M., Andersson, David A., Rash, Lachlan D., Wood, John N. ... Vetter, Irina (2023). Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function. Nature Communications, 14 (1) 2442. doi: 10.1038/s41467-023-37963-2

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

2022

Journal Article

Venom-derived pain-causing toxins: insights into sensory neuron function and pain mechanisms

Robinson, Samuel D., Deuis, Jennifer R., Klasfauseweh, Tabea, Schendel, Vanessa and Vetter, Irina (2022). Venom-derived pain-causing toxins: insights into sensory neuron function and pain mechanisms. Pain, 163 (S1), S46-S56. doi: 10.1097/j.pain.0000000000002701

Venom-derived pain-causing toxins: insights into sensory neuron function and pain mechanisms

2022

Journal Article

Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation

Klasfauseweh, Tabea, Israel, Mathilde R., Ragnarsson, Lotten, Cox, James J., Durek, Thomas, Carter, David A., Leffler, Andreas, Vetter, Irina and Deuis, Jennifer R. (2022). Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation. European Journal of Pharmacology, 925 175013, 175013. doi: 10.1016/j.ejphar.2022.175013

Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation