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2026

Journal Article

Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines

Soltau, Carl P., Tay, Ban Qi, Richard, Derek J., Bottle, Steven E. and Adams, Mark N. (2026). Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines. Biomedicine & Pharmacotherapy, 198 119348, 119348. doi: 10.1016/j.biopha.2026.119348

Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines

2026

Journal Article

Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state

Soltau, Carl P., Tay, Ban Qi, Martyn, Alexander P., Richard, Derek J., Adams, Mark N. and Bottle, Steven E. (2026). Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state. European Journal of Medicinal Chemistry, 307 118655, 1-16. doi: 10.1016/j.ejmech.2026.118655

Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state

2026

Journal Article

Redox-active nitroxides enhance cisplatin efficacy against cervical cancer

Soltau, Carl P., Sinha, Debottam, Patil, Lakshita P., Moseley, Philip M., Rayner, Cassie L., Barnett, Nigel L., Richard, Derek J., Bottle, Steven E., Frazer, Ian H. and Martyn, Alexander P. (2026). Redox-active nitroxides enhance cisplatin efficacy against cervical cancer. Redox Biology, 89 103989, 1-13. doi: 10.1016/j.redox.2025.103989

Redox-active nitroxides enhance cisplatin efficacy against cervical cancer

2025

Journal Article

Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions

Brown, Zachary E., Soltau, Carl P., Marshall, David L., Bottle, Steven E. and Miljevic, Branka (2025). Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions. RSC Advances, 15 (32), 26395-26402. doi: 10.1039/d5ra03412d

Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions

2024

Journal Article

Synthesis of anti-oxidant steroids by hybridisation with nitroxides

Soltau, Carl P., Weir, Naomi E., Martyn, Alexander P. and Bottle, Steven E. (2024). Synthesis of anti-oxidant steroids by hybridisation with nitroxides. Synthesis, 56 (21), 3289-3296. doi: 10.1055/a-2232-8240

Synthesis of anti-oxidant steroids by hybridisation with nitroxides

2023

Journal Article

An exploration of small molecules that bind human single-stranded DNA binding protein 1

Schuurs, Zachariah P., Martyn, Alexander P., Soltau, Carl P., Beard, Sam, Shah, Esha T., Adams, Mark N., Croft, Laura V., O'Byrne, Kenneth J., Richard, Derek J. and Gandhi, Neha S. (2023). An exploration of small molecules that bind human single-stranded DNA binding protein 1. Biology, 12 (11) 1405, 1-23. doi: 10.3390/biology12111405

An exploration of small molecules that bind human single-stranded DNA binding protein 1

2022

Journal Article

Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter

Soltau, Carl P., Brown, Zac E., Brock, Aidan J., Martyn, Alexander P., Blinco, James P., Miljevic, Branka, McMurtrie, John C. and Bottle, Steven E. (2022). Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter. Chemical Communications, 58 (74), 10416-10419. doi: 10.1039/d2cc04024g

Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter