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2025 Journal Article Traditional Chinese medicine borneol‐based polymeric micelles intracerebral drug delivery system for precisely pathogenesis‐adaptive treatment of ischemic strokeWang, Yanan, Ma, Xutao, Wang, Xinyuan, Liu, Liru, Zhang, Xue, Wang, Qiuyue, Zhu, Yingfei, Xu, Huanhua, Yu, Liangmin and He, Zhiyu (2025). Traditional Chinese medicine borneol‐based polymeric micelles intracerebral drug delivery system for precisely pathogenesis‐adaptive treatment of ischemic stroke. Advanced Science, 12 (9) 2410889, 1-23. doi: 10.1002/advs.202410889 |
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2025 Journal Article “Two-birds-one-stone” oral colon-targeted nanomedicine for ulcerative colitis precise therapy via remodeling inflammation microenvironment and inhibiting lipid peroxidation/ferroptosisLiu, Ruiqing, Yan, Jiahui, Wang, Zhibo, Liu, Hong, Ma, Xutao, Wang, Yanan, Sun, Xueping, Zhang, Baomei, Zhao, Wuqun, Zhang, Junhao, He, Zhiyu and Lu, Yun (2025). “Two-birds-one-stone” oral colon-targeted nanomedicine for ulcerative colitis precise therapy via remodeling inflammation microenvironment and inhibiting lipid peroxidation/ferroptosis. Chemical Engineering Journal, 505 159736, 1-19. doi: 10.1016/j.cej.2025.159736 |
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2025 Journal Article Two-pronged nanostrategy for treating ALI and blocking pulmonary fibrosis through intracellular/extracellular synergistic intervention to restore mitochondrial homeostasis and inhibit inflammationYan, Jiahui, Sun, Xueping, Wang, Yanan, Meng, Xinlei, Liu, Hong, Zhang, Baomei, Wang, Qiuyue, Wei, Sixian, Ma, Xutao, Chi, Kai, Xu, Huanhua, Yu, Liangmin and He, Zhiyu (2025). Two-pronged nanostrategy for treating ALI and blocking pulmonary fibrosis through intracellular/extracellular synergistic intervention to restore mitochondrial homeostasis and inhibit inflammation. Chemical Engineering Journal, 506 159903, 1-24. doi: 10.1016/j.cej.2025.159903 |
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2024 Journal Article Flash nanocomplexation (FNC): A new microvolume mixing method for nanomedicine formulationLi, Keyang, Wang, Yanan, Xu, Yatao, Shi, Guohua, Wei, Sixian, Zhang, Xue, Zhang, Baomei, Jia, Qiang, Xu, Huanhua, Yu, Liangmin, Wu, Jun and He, Zhiyu (2024). Flash nanocomplexation (FNC): A new microvolume mixing method for nanomedicine formulation. Chinese Chemical Letters, 35 (10) 109511, 1-14. doi: 10.1016/j.cclet.2024.109511 |
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2024 Journal Article Self-sulfhydrated, nitro-fixed albumin nanoparticles as a potent therapeutic agent for the treatment of acute liver injuryWang, Yanan, Liu, Xiaohu, Li, Keyang, Wang, Xinyuan, Zhang, Xue, Qian, Deyao, Meng, Xinlei, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2024). Self-sulfhydrated, nitro-fixed albumin nanoparticles as a potent therapeutic agent for the treatment of acute liver injury. ACS Nano, 18 (31), 20772-20791. doi: 10.1021/acsnano.4c07297 |
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2024 Journal Article Biomimetic trypsin-responsive structure-bridged mesoporous organosilica nanomedicine for precise treatment of acute pancreatitisWang, Yanan, Qian, Deyao, Wang, Xinyuan, Zhang, Xue, Li, Zerui, Meng, Xinlei, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2024). Biomimetic trypsin-responsive structure-bridged mesoporous organosilica nanomedicine for precise treatment of acute pancreatitis. ACS Nano, 18 (29), 19283-19302. doi: 10.1021/acsnano.4c05369 |
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2024 Journal Article Inflammation and acinar cell dual-targeting nanomedicines for synergistic treatment of acute pancreatitis via Ca2+ homeostasis regulation and pancreas autodigestion inhibitionWang, Yanan, Wang, Xinyuan, Zhang, Xue, Zhang, Baomei, Meng, Xinlei, Qian, Deyao, Xu, Yatao, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2024). Inflammation and acinar cell dual-targeting nanomedicines for synergistic treatment of acute pancreatitis via Ca2+ homeostasis regulation and pancreas autodigestion inhibition. ACS Nano, 18 (18), 11778-11803. doi: 10.1021/acsnano.4c00218 |
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2024 Journal Article Restoring cellular calcium homeostasis to rescue ER stress by 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid acetoxymethyl ester-loaded lipid-mPLGA hybrid-nanoparticles for acute kidney injury therapyZhang, Jingwen, Yan, Jiahui, Wang, Yanan, Liu, Hong, Sun, Xueping, Gu, Yuchao, Yu, Liangmin, Li, Changcheng, Wu, Jun and He, Zhiyu (2024). Restoring cellular calcium homeostasis to rescue ER stress by 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid acetoxymethyl ester-loaded lipid-mPLGA hybrid-nanoparticles for acute kidney injury therapy. Chinese Chemical Letters, 35 (3) 108434, 1-9. doi: 10.1016/j.cclet.2023.108434 |
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2024 Journal Article Ros-responsive dextran-phenylboronic acid-silibinin nanoparticles for targeting delivery of BAPTA-AM to effectively eliminate calcium overload-mediated inflammatory cascades and mitochondrial apoptosis: Alleviating acute liver injuryWang, Yanan, Wei, Huichao, Li, Keyang, Liu, Liru, Zhu, Yingfei, Wang, Xinyuan, Yan, Jiahui, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2024). Ros-responsive dextran-phenylboronic acid-silibinin nanoparticles for targeting delivery of BAPTA-AM to effectively eliminate calcium overload-mediated inflammatory cascades and mitochondrial apoptosis: Alleviating acute liver injury. Chemical Engineering Journal, 480 148283, 1-18. doi: 10.1016/j.cej.2023.148283 |
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2023 Journal Article Marine biomaterials in biomedical nano/micro-systemsWang, Yanan, Chen, Long, Wang, Yuanzheng, Wang, Xinyuan, Qian, Deyao, Yan, Jiahui, Sun, Zeyu, Cui, Pengfei, Yu, Liangmin, Wu, Jun and He, Zhiyu (2023). Marine biomaterials in biomedical nano/micro-systems. Journal of Nanobiotechnology, 21 (1) 408, 1-48. doi: 10.1186/s12951-023-02112-w |
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2023 Journal Article Rapidly inhibiting the inflammatory cytokine storms and restoring cellular homeostasis to alleviate sepsis by blocking pyroptosis and mitochondrial apoptosis pathwaysYan, Jiahui, Zhang, Jingwen, Wang, Yanan, Liu, Hong, Sun, Xueping, Li, Aixin, Cui, Pengfei, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2023). Rapidly inhibiting the inflammatory cytokine storms and restoring cellular homeostasis to alleviate sepsis by blocking pyroptosis and mitochondrial apoptosis pathways. Advanced Science, 10 (14) 2207448, 1-20. doi: 10.1002/advs.202207448 |
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2023 Journal Article Rapidly blocking the calcium overload/ROS production feedback loop to alleviate acute kidney injury via microenvironment‐responsive BAPTA‐AM/BAC co‐delivery nanosystemYan, Jiahui, Wang, Yanan, Zhang, Jingwen, Liu, Xiaohu, Yu, Liangmin and He, Zhiyu (2023). Rapidly blocking the calcium overload/ROS production feedback loop to alleviate acute kidney injury via microenvironment‐responsive BAPTA‐AM/BAC co‐delivery nanosystem. Small, 19 (17) 2206936, 1-18. doi: 10.1002/smll.202206936 |
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2022 Journal Article 1,2-Bis(2-aminophenoxy)ethane‑N,N,N′,N′‑tetraacetic Acid Acetoxymethyl Ester Loaded Reactive Oxygen Species Responsive Hyaluronic Acid–Bilirubin Nanoparticles for Acute Kidney Injury Therapy via Alleviating Calcium Overload Mediated Endoplasmic Reticulum StressWang, Yanan, Pu, Minju, Yan, Jiahui, Zhang, Jingwen, Wei, Huichao, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2022). 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic Acid Acetoxymethyl Ester Loaded Reactive Oxygen Species Responsive Hyaluronic Acid–Bilirubin Nanoparticles for Acute Kidney Injury Therapy via Alleviating Calcium Overload Mediated Endoplasmic Reticulum Stress. ACS Nano, 17 (1), 472-491. doi: 10.1021/acsnano.2c08982 |
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2022 Journal Article Innovations and challenges of polyphenol-based smart drug delivery systemsWang, Yanan, Zhang, Jingwen, Zhao, Yi, Pu, Minju, Song, Xinyu, Yu, Liangmin, Yan, Xuefeng, Wu, Jun and He, Zhiyu (2022). Innovations and challenges of polyphenol-based smart drug delivery systems. Nano Research, 15 (9), 8156-8184. doi: 10.1007/s12274-022-4430-3 |
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2022 Journal Article The Advancement of Gas‐Generating Nanoplatforms in Biomedical Fields: Current Frontiers and Future PerspectivesYan, Jiahui, Wang, Yanan, Song, Xinyu, Yan, Xuefeng, Zhao, Yi, Yu, Liangmin and He, Zhiyu (2022). The Advancement of Gas‐Generating Nanoplatforms in Biomedical Fields: Current Frontiers and Future Perspectives. Small Methods, 6 (7) 2200139. doi: 10.1002/smtd.202200139 |
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2022 Journal Article Kinetic control of Phytic acid/Lixisenatide/Fe (III) ternary nanoparticles assembly process for sustained peptide releaseWang, Yanan, Song, Xinyu, Zhuang, Liwei, Lang, Haifeng, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2022). Kinetic control of Phytic acid/Lixisenatide/Fe (III) ternary nanoparticles assembly process for sustained peptide release. International Journal of Pharmaceutics, 611 121317, 121317. doi: 10.1016/j.ijpharm.2021.121317 |
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2021 Journal Article Dealing with MDR bacteria and biofilm in the post-antibiotic era: Application of antimicrobial peptides-based nano-formulationSong, Xinyu, Liu, Pengyan, Liu, Xiaohu, Wang, Yanan, Wei, Huichao, Zhang, Jingwen, Yu, Liangmin, Yan, Xuefeng and He, Zhiyu (2021). Dealing with MDR bacteria and biofilm in the post-antibiotic era: Application of antimicrobial peptides-based nano-formulation. Materials Science and Engineering: C, 128 112318, 112318-128. doi: 10.1016/j.msec.2021.112318 |
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2021 Journal Article Application of nanotechnology in acute kidney injury: from diagnosis to therapeutic implicationsZhao, Yi, Pu, Mingju, Wang, Yanan, Yu, Liangmin, Song, Xinyu and He, Zhiyu (2021). Application of nanotechnology in acute kidney injury: from diagnosis to therapeutic implications. Journal of Controlled Release, 336, 233-251. doi: 10.1016/j.jconrel.2021.06.026 |
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2021 Journal Article Recent advancements of nanomaterial-based therapeutic strategies toward sepsis: bacterial eradication, anti-inflammation, and immunomodulationZhao, Yi, Pu, Minju, Zhang, Jingwen, Wang, Yanan, Yan, Xuefeng, Yu, Liangmin and He, Zhiyu (2021). Recent advancements of nanomaterial-based therapeutic strategies toward sepsis: bacterial eradication, anti-inflammation, and immunomodulation. Nanoscale, 13 (24), 10726-10747. doi: 10.1039/d1nr02706a |
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2021 Journal Article Sustained release systems for delivery of therapeutic peptide/proteinNie, Tianqi, Wang, Wei, Liu, Xiaohu, Wang, Yanan, Li, Keyang, Song, Xinyu, Zhang, Jingwen, Yu, Liangmin and He, Zhiyu (2021). Sustained release systems for delivery of therapeutic peptide/protein. Biomacromolecules, 22 (6), 2299-2324. doi: 10.1021/acs.biomac.1c00160 |
