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2025 Journal Article Pembrolizumab (Pembro) plus R-CHOP is efficacious as first-line therapy for primary mediastinal B-cell lymphoma (PMBL) with high rates of ctdna negativity – interim efficacy analysis of the ALLG-Pacific (NHL35) trialLewis, Katharine, Blombery, Piers, Sungala, Nagendra Prasad, Giri, Pratyush, Marconi, Tamara, Cochrane, Tara, Francis, Roslyn, Lee, Sze-Ting, Ma, Chun Kei Kris, Vanguru, Vinay, Manos, Kate, Keane, Colm, Hunter, Sally, Burgess, Melinda, Kannan, Sushmitha, Carlson, Julia, Walia, Mannu, Butcher, Belinda and Cheah, Chan (2025). Pembrolizumab (Pembro) plus R-CHOP is efficacious as first-line therapy for primary mediastinal B-cell lymphoma (PMBL) with high rates of ctdna negativity – interim efficacy analysis of the ALLG-Pacific (NHL35) trial. Blood, 146 (Supplement 1), 1016-1016. doi: 10.1182/blood-2025-1016 |
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2025 Journal Article Trial in progress: Treatment of CNS lymphoma with zanubrutinib and tislelizumab: A phase ib/II investigator-initiated studySalvaris, Ross, Keane, Colm, Trotman, Judith, Sutherland, Antony, Waltham, Mark, Simpson, David, Gregory, Gareth P. and Opat, Stephen (2025). Trial in progress: Treatment of CNS lymphoma with zanubrutinib and tislelizumab: A phase ib/II investigator-initiated study. Blood, 146 (Supplement 1), 1926-1926. doi: 10.1182/blood-2025-1926 |
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2025 Journal Article Distinct immune checkpoint landscapes in PCNSL and SCNSL revealed by single-nucleus profilingHawula, Zachary, Tuczko, Nella, Burgess, Melinda, Bradbury, Lucy, Chowdhury, Rakin, Swain, Fiona, Hawkes, Eliza, Wight, Joel and Keane, Colm (2025). Distinct immune checkpoint landscapes in PCNSL and SCNSL revealed by single-nucleus profiling. Blood, 146 (Supplement 1), 149-149. doi: 10.1182/blood-2025-149 |
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2025 Journal Article Expression of the cancer testis antigen PRAME is associated with response to immune checkpoint inhibitor and rituximab priming in treatment-naïve diffuse large B-cell lymphomaManos, Kate, Burgess, Melinda, Chong, Geoffrey, Lee, Sze-Ting, Smith, Charmaine, Renwick, William, Kempe, Sarah, Murigneux, Valentine, Chowdhury, Rakin, Blombery, Piers, Nelson, Niles, Fancourt, Tineke, Hawking, Joanne, Lin, Wendi, Barraclough, Allison, Wight, Joel, Keane, Colm and Hawkes, Eliza (2025). Expression of the cancer testis antigen PRAME is associated with response to immune checkpoint inhibitor and rituximab priming in treatment-naïve diffuse large B-cell lymphoma. Blood, 146 (Supplement 1), 3306-3306. doi: 10.1182/blood-2025-3306 |
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2025 Journal Article Characterizing the mechanistic role of TNF signaling via TNFR1 and TNFR2 on NK cell-mediated anti-tumor immunity 2859Alim, Louisa Frances, Lam, Pui Yeng, Keane, Colm and Souza-Fonseca-Guimaraes, Fernando (2025). Characterizing the mechanistic role of TNF signaling via TNFR1 and TNFR2 on NK cell-mediated anti-tumor immunity 2859. The Journal of Immunology, 214 (Supplement_1) vkaf283.730. doi: 10.1093/jimmun/vkaf283.730 |
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2025 Journal Article T-cell dysregulation informs radiotherapy-immunotherapy response in B-cell lymphoma: results from a Phase I trialHawkes, Eliza A., Palmer, Jodie, Khor, Richard, Lee, Sze Ting, Burgess, Melinda, Law, Soi C., Gandhi, Maher K., Chong, Geoffrey, Shortt, Jake, Chowdhury, Rakin, Swain, Fiona, Churilov, Leonid, MacManus, Michael M., Smith, Charmaine, Scott, Fiona Elizabeth, Martynchyk, Arina, Barraclough, Allison, Manos, Kate, Scott, Andrew M. and Keane, Colm (2025). T-cell dysregulation informs radiotherapy-immunotherapy response in B-cell lymphoma: results from a Phase I trial. Blood Advances, 9 (20), 5263-5273. doi: 10.1182/bloodadvances.2025016505 |
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2025 Journal Article T cell immune profile changes predict durable response to nivolumab-rituximab in treatment naïve FLKoldej, Rachel M, Barraclough, Allison, Morgan, Huw, Lee, Sze Ting, Holzwart, Nicholas, Koshy, Minu, Smith, Charmaine, Chong, Geoff, Gilbertson, Michael, Keane, Colm, Lee, Denise, Churilov, Leonid, Ritchie, David S and Hawkes, Eliza A (2025). T cell immune profile changes predict durable response to nivolumab-rituximab in treatment naïve FL. Blood Neoplasia, 2 (4) 100168, 100168. doi: 10.1016/j.bneo.2025.100168 |
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2025 Journal Article Meeting trial eligibility in follicular lymphoma patients is associated with overall survival but not progression-free survivalWong, Kimberly S Q, Martynchyk, Arina, Krisnadi, Zoe, Swain, Fiona, Zargari, Ahmad, Cassidy, Luke, Mills, Georgia, Lim, Kenneth, Gervasi, Jeremy, Smallbone, Portia, Wang, Jenny, Slifirski, Olivia, Loh, Zoe, Cheah, Chan, Keane, Colm, Gregory, Gareth, Lasica, Masa, Chong, Geoffrey, Barraclough, Allison, Cochrane, Tara, Lee, Denise and Hawkes, Eliza (2025). Meeting trial eligibility in follicular lymphoma patients is associated with overall survival but not progression-free survival. JNCI: Journal of the National Cancer Institute, 117 (11) djaf174, 2240-2248. doi: 10.1093/jnci/djaf174 |
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2025 Journal Article Refinement of primary central nervous system lymphoma prognostication and response assessment using 3-dimensional MRIO’Shaughnessy, Jack, Martynchyk, Arina, Lee, Sze Ting, Chong, Geoff, Agrawal, Shivam, Tatarczuch, Maciej, Azryn, Nariza Alysa, Gregory, Gareth P., Churilov, Leonid, Wang, Michael, Keane, Colm and Hawkes, Eliza A. (2025). Refinement of primary central nervous system lymphoma prognostication and response assessment using 3-dimensional MRI. Neuro-Oncology Advances, 7 (1) vdaf090, vdaf090. doi: 10.1093/noajnl/vdaf090 |
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2025 Journal Article Nivolumab and rituximab in treatment naive follicular lymphoma: the phase II '1st FLOR' studyBarraclough, Allison, Lee, Sze Ting, Burgess, Melinda, Churilov, Leonid, Chong, Geoffrey, Lee, Denise, Gilbertson, Michael, Fancourt, Tineke, Manos, Kate, Ritchie, David, Koldej, Rachel M, Scott, Andrew, Keane, Colm and Hawkes, Eliza A (2025). Nivolumab and rituximab in treatment naive follicular lymphoma: the phase II '1st FLOR' study. Blood Advances, 9 (6), 1432-1441. doi: 10.1182/bloodadvances.2024015487 |
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2024 Journal Article Adjuvant rituximab and elevated intratumoural CD8 expression are associated with sustained disease control after radiotherapy in a randomised trial of systemic therapy in early-stage follicular lymphomaMacManus, Michael P., Seymour, John F., Tsang, Hennes, Fisher, Richard, Keane, Colm, Sabdia, Muhammed B., Law, Soi C., Gunawardana, Jay, Nath, Karthik, Kazakoff, Stephen H., Marques-Piubelli, Mario L., Duenas, Daniela E., Green, Michael R., Roos, Daniel, O'Brien, Peter, McCann, Andrew, Tsang, Richard, Davis, Sidney, Christie, David, Cheah, Chan, Amanuel, Benhur, Cochrane, Tara, Butler, Jason, Johnston, Anna, Shanavas, Mohamed, Li, Li, Vajdic, Claire, Kridel, Robert, Shelton, Victoria ... Tobin, Joshua W. D. (2024). Adjuvant rituximab and elevated intratumoural CD8 expression are associated with sustained disease control after radiotherapy in a randomised trial of systemic therapy in early-stage follicular lymphoma. eBioMedicine, 110 105468, 1-13. doi: 10.1016/j.ebiom.2024.105468 |
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2024 Journal Article Magrolimab plus rituximab with/without chemotherapy in patients with relapsed/refractory diffuse large B-cell lymphomaMaakaron, Joeseph, Asch, Adam S., Popplewell, Leslie, Collins, Graham P., Flinn, Ian W., Ghosh, Nilanjan, Keane, Colm, Ku, Matthew, Mehta, Amitkumar, Roschewski, Mark, Hacohen-Kleiman, Gal, Huo, Yanan, Zhang, Yi, Renard, Camille, Smith, Sonali M. and Advani, Ranjana H. (2024). Magrolimab plus rituximab with/without chemotherapy in patients with relapsed/refractory diffuse large B-cell lymphoma. Blood Advances, 8 (22), 5864-5874. doi: 10.1182/bloodadvances.2024013338 |
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2024 Journal Article Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammationMcCulloch, Timothy R., Rossi, Gustavo R., Alim, Louisa, Lam, Pui Yeng, Wong, Joshua K. M., Coleborn, Elaina, Kumari, Snehlata, Keane, Colm, Kueh, Andrew J., Herold, Marco J., Wilhelm, Christoph, Knolle, Percy A., Kane, Lawrence, Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2024). Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation. Nature Communications, 15 (1) 9871, 1-16. doi: 10.1038/s41467-024-54232-y |
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2024 Journal Article Intra‐tumoral and peripheral blood TIGIT and PD‐1 as immune biomarkers in nodular lymphocyte predominant Hodgkin lymphomaGunawardana, Jay, Law, Soi C., Sabdia, Muhammed B., Fennell, Éanna, Hennessy, Aoife, Leahy, Ciara I., Murray, Paul G., Bednarska, Karolina, Brosda, Sandra, Trotman, Judith, Berkahn, Leanne, Zaharia, Andreea, Birch, Simone, Burgess, Melinda, Talaulikar, Dipti, Lee, Justina N., Jude, Emily, Hawkes, Eliza A., Jain, Sanjiv, Nath, Karthik, Snell, Cameron, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Shanavas, Mohamed, Blyth, Emily, Steidl, Christian, Savage, Kerry, Farinha, Pedro ... Gandhi, Maher K. (2024). Intra‐tumoral and peripheral blood TIGIT and PD‐1 as immune biomarkers in nodular lymphocyte predominant Hodgkin lymphoma. American Journal of Hematology, 99 (11), 2096-2107. doi: 10.1002/ajh.27459 |
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2024 Journal Article Genetic and immunological features of immune deficiency and dysregulation‐associated lymphoproliferations and lymphomas as a basis for classificationDierickx, Daan, Keane, Colm and Natkunam, Yasodha (2024). Genetic and immunological features of immune deficiency and dysregulation‐associated lymphoproliferations and lymphomas as a basis for classification. Histopathology, 86 (1), 106-118. doi: 10.1111/his.15342 |
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2024 Journal Article Impact and utility of follicular lymphoma GELF criteria in routine care: an Australasian Lymphoma Alliance studyBarraclough, Allison, Agrawal, Shivam, Talaulikar, Dipti, Chong, Geoffrey, Yoo, Edward, Cheah, Chan Y., Franco, Nunzio, Nguyen, Bianca, Mutsando, Howard, Tahir, Fatima, Trotman, Judith, Huang, Jing, Keane, Colm, Lincoln, Mitchel, Cochrane, Tara, Johnston, Anna M., Dickinson, Michael, Opat, Stephen, McQuilten, Zoe K., Wood, Erica M., St George, Gayathri and Hawkes, Eliza A. (2024). Impact and utility of follicular lymphoma GELF criteria in routine care: an Australasian Lymphoma Alliance study. Haematologica, 109 (10), 3338-3345. doi: 10.3324/haematol.2023.284538 |
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2024 Journal Article Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillanceWight, Joel, Blombery, Piers, Lickiss, Jennifer, Burgess, Melinda, Gould, Clare, Minson, Adrian, Swain, Fiona, Sabdia, Muhammed B., Gandhi, Maher K., Birchley, Andrew, Keane, Colm and Hawkes, Eliza A. (2024). Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillance. Haematologica, 109 (9), 3013-3018. doi: 10.3324/haematol.2023.284600 |
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2024 Journal Article Poor outcomes for trial‐ineligible patients receiving polatuzumab for relapsed/refractory diffuse large B‐cell lymphoma in routine care: An Australian Lymphoma and Related Diseases Registry projectShaw, Briony, Chung, Eliza, Wellard, Cameron, Yoo, Edward, Bennett, Rory, Birks, Callum, Johnston, Anna, Cheah, Chan Y, Hamad, Nada, Simpson, Jock, Barraclough, Allison, Ku, Matthew, Viiala, Nicholas, Ratnasingam, Sumita, Armytage, Tasman, Cochrane, Tara, Chong, Geoffrey, Lee, Denise, Manos, Kate, Keane, Colm, Wallwork, Stephanie, Opat, Stephen and Hawkes, Eliza A. (2024). Poor outcomes for trial‐ineligible patients receiving polatuzumab for relapsed/refractory diffuse large B‐cell lymphoma in routine care: An Australian Lymphoma and Related Diseases Registry project. eJHaem, 5 (2), 325-332. doi: 10.1002/jha2.870 |
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2024 Journal Article Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironmentAlim, Louisa F., Keane, Colm and Souza-Fonseca-Guimaraes, Fernando (2024). Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment. Current Opinion in Immunology, 86 102409, 102409. doi: 10.1016/j.coi.2023.102409 |
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2024 Journal Article Epstein–Barr virus‐associated lymphomas decodedBednarska, Karolina, Chowdhury, Rakin, Tobin, Joshua W. D., Swain, Fiona, Keane, Colm, Boyle, Stephen, Khanna, Rajiv and Gandhi, Maher K. (2024). Epstein–Barr virus‐associated lymphomas decoded. British Journal of Haematology, 204 (2), 415-433. doi: 10.1111/bjh.19255 |
