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2015

Journal Article

Familial disorders of the optic disc: presentation of a mother and daughter and review of the literature

Hsu, Chia Lee and Layton, Christopher J. (2015). Familial disorders of the optic disc: presentation of a mother and daughter and review of the literature. Case Reports in Ophthalmology, 6 (2), 251-259. doi: 10.1159/000437381

Familial disorders of the optic disc: presentation of a mother and daughter and review of the literature

2014

Journal Article

Factors associated with significant ocular injury in conservatively treated orbital fractures

Layton, Christopher J. (2014). Factors associated with significant ocular injury in conservatively treated orbital fractures. Journal of Ophthalmology, 2014 412397, 412397.1-412397.6. doi: 10.1155/2014/412397

Factors associated with significant ocular injury in conservatively treated orbital fractures

2004

Journal Article

Monocarboxylate transporter expression remains unchanged during the development of diabetic retinal neuropathy in the rat

Layton, Christopher J., Chidlow, Glyn, Casson, Robert J., Wood, John P. M., Graham, Mark and Osborne, Neville N. (2004). Monocarboxylate transporter expression remains unchanged during the development of diabetic retinal neuropathy in the rat. Investigative Ophthalmology and Visual Science, 46 (8), 2878-2885. doi: 10.1167/iovs.04-1458

Monocarboxylate transporter expression remains unchanged during the development of diabetic retinal neuropathy in the rat

2024

Journal Article

AAV-mediated gene therapies for glaucoma and uveitis: are we there yet?

Castro, Brenda, Steel, Jason C. and Layton, Christopher J. (2024). AAV-mediated gene therapies for glaucoma and uveitis: are we there yet?. Expert Reviews in Molecular Medicine, 26 e9, e9. doi: 10.1017/erm.2024.4

AAV-mediated gene therapies for glaucoma and uveitis: are we there yet?

2023

Journal Article

AAV-based strategies for treatment of retinal and choroidal vascular diseases: advances in age-related macular degeneration and diabetic retinopathy therapies

Castro, Brenda F. M., Steel, Jason C. and Layton, Christopher J. (2023). AAV-based strategies for treatment of retinal and choroidal vascular diseases: advances in age-related macular degeneration and diabetic retinopathy therapies. BioDrugs, 38 (1), 73-93. doi: 10.1007/s40259-023-00629-y

AAV-based strategies for treatment of retinal and choroidal vascular diseases: advances in age-related macular degeneration and diabetic retinopathy therapies

2022

Journal Article

Attitudes of eye health practitioners towards diagnostic tests and therapies for dry eye disease in Australasia

Li, Ye, Smith, Robert G., Steel, Jason C. and Layton, Christopher J. (2022). Attitudes of eye health practitioners towards diagnostic tests and therapies for dry eye disease in Australasia. Contact Lens and Anterior Eye, 45 (6) 101724, 1-6. doi: 10.1016/j.clae.2022.101724

Attitudes of eye health practitioners towards diagnostic tests and therapies for dry eye disease in Australasia

2021

Journal Article

Differences in uveal melanoma age-standardized incidence rates in two eastern states of Australia are driven by differences in rurality and ultraviolet radiation

Chalada, Melissa, Ramlogan-steel, Charmaine A., Dhungel, Bijay P., Goh, Amanda Y., Gardiner, Samuel, Layton, Christopher J. and Steel, Jason C. (2021). Differences in uveal melanoma age-standardized incidence rates in two eastern states of Australia are driven by differences in rurality and ultraviolet radiation. Cancers, 13 (23) 5894, 5894. doi: 10.3390/cancers13235894

Differences in uveal melanoma age-standardized incidence rates in two eastern states of Australia are driven by differences in rurality and ultraviolet radiation

2021

Other Outputs

Expression vector and method

Layton, Christopher and Steel, Jason (2021). Expression vector and method. US Patent App. 16/963,880.

Expression vector and method

2021

Journal Article

Neutralisation of adeno-associated virus transduction by human vitreous humour

Andrzejewski, Sławomir, Moyle, Peter M., Stringer, Brett W., Steel, Jason C. and Layton, Christopher J. (2021). Neutralisation of adeno-associated virus transduction by human vitreous humour. Gene Therapy, 28 (5), 242-255. doi: 10.1038/s41434-020-0162-8

Neutralisation of adeno-associated virus transduction by human vitreous humour

2021

Journal Article

The impact of ultraviolet radiation on the aetiology and development of uveal melanoma

Chalada, Melissa, Ramlogan-Steel, Charmaine A., Dhungel, Bijay P., Layton, Christopher J. and Steel, Jason C. (2021). The impact of ultraviolet radiation on the aetiology and development of uveal melanoma. Cancers, 13 (7) 1700, 1700. doi: 10.3390/cancers13071700

The impact of ultraviolet radiation on the aetiology and development of uveal melanoma

2020

Journal Article

Time‐to‐event survival statistics in ophthalmology: methodological research

Layton, Christopher J. and Layton, Danielle M. (2020). Time‐to‐event survival statistics in ophthalmology: methodological research. Clinical and Experimental Ophthalmology, 48 (9) ceo.13848, 1136-1145. doi: 10.1111/ceo.13848

Time‐to‐event survival statistics in ophthalmology: methodological research

2020

Journal Article

Characterisation and validation of the 8-fold quadrant dissected human retinal explant culture model for pre-clinical toxicology investigation

Murali, Aparna, Ramlogan-Steel, Charmaine A., Steel, Jason C. and Layton, Christopher J. (2020). Characterisation and validation of the 8-fold quadrant dissected human retinal explant culture model for pre-clinical toxicology investigation. Toxicology in Vitro, 63 104716, 1-10. doi: 10.1016/j.tiv.2019.104716

Characterisation and validation of the 8-fold quadrant dissected human retinal explant culture model for pre-clinical toxicology investigation

2020

Journal Article

Presence and prevalence of uv related genetic mutations in uveal melanoma: similarities with cutaneous melanoma

Goh, A. Y., Ramlogan-Steel, C. A., Jenkins, K. S., Steel, J. C. and Layton, C. J. (2020). Presence and prevalence of uv related genetic mutations in uveal melanoma: similarities with cutaneous melanoma. Neoplasma, 67 (5), 958-971. doi: 10.4149/neo_2020_190815N768

Presence and prevalence of uv related genetic mutations in uveal melanoma: similarities with cutaneous melanoma

2020

Conference Publication

Recombinant Adeno-Associated Virus Vector Tropism in Human Retina

Andrzejewski, Slawomir, Moyle, Peter M., Stringer, Brett W., Steel, Jason and Layton, Christopher J. (2020). Recombinant Adeno-Associated Virus Vector Tropism in Human Retina. In: 23rd Annual Meeting of the American Society for Gene and Cell Therapy, Electr Network, (254-254). 12-15 May 2020.

Recombinant Adeno-Associated Virus Vector Tropism in Human Retina

2019

Journal Article

Gene therapy and the adeno associated virus in the treatment of genetic and acquired ophthalmic diseases in humans: trials, future directions and safety considerations

Ramlogan-Steel, Charmaine A., Murali, Aparna, Andrzejewski, Slawomir, Dhungel, Bijay, Steel, Jason C. and Layton, Christopher J. (2019). Gene therapy and the adeno associated virus in the treatment of genetic and acquired ophthalmic diseases in humans: trials, future directions and safety considerations. Clinical & Experimental Ophthalmology, 47 (4), 521-536. doi: 10.1111/ceo.13416

Gene therapy and the adeno associated virus in the treatment of genetic and acquired ophthalmic diseases in humans: trials, future directions and safety considerations

2019

Journal Article

Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus

Andrzejewski, Slawomir, Murali, Aparna, Ramlogan-Steel, Charmaine, Edwards, Katie P., Efron, Nathan, Steel, Jason C. and Layton, Christopher J. (2019). Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus. Gene Therapy, 26 (6), 250-263. doi: 10.1038/s41434-019-0076-5

Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus

2019

Conference Publication

Effect of human vitreous humour components and neutralising antibodies on transduction activity of recombinant AAV2, AAV5, AAV6 and AAV8

Andrzejewski, S., Moyle, P., Stringer, B., Steel, J. and Layton, C. J. (2019). Effect of human vitreous humour components and neutralising antibodies on transduction activity of recombinant AAV2, AAV5, AAV6 and AAV8. Annual Conference of the British-Society-for-Gene-and-Cell-Therapy, Sheffield, United Kingdom , 19-21 June 2019. New Rochelle, NY, United States: Mary Ann Liebert.

Effect of human vitreous humour components and neutralising antibodies on transduction activity of recombinant AAV2, AAV5, AAV6 and AAV8

2018

Journal Article

Systematic assessment of clinical methods to diagnose and monitor diabetic retinal neuropathy

Jenkins, K. Sean, Steel, Jason C. and Layton, Christopher J. (2018). Systematic assessment of clinical methods to diagnose and monitor diabetic retinal neuropathy. Journal of Ophthalmology, 2018 8479850, 1-9. doi: 10.1155/2018/8479850

Systematic assessment of clinical methods to diagnose and monitor diabetic retinal neuropathy

2018

Journal Article

microRNA199a based post-transcriptional detargeting of gene vectors for Hepatocellular Carcinoma

Dhungel, Bijay, Ramlogan-Steel, Charmaine A., Layton, Christopher J. and Steel, Jason C. (2018). microRNA199a based post-transcriptional detargeting of gene vectors for Hepatocellular Carcinoma. Molecular Therapy - Nucleic Acids, 13, 78-88. doi: 10.1016/j.omtn.2018.08.016

microRNA199a based post-transcriptional detargeting of gene vectors for Hepatocellular Carcinoma

2018

Journal Article

Retinal explant culture: a platform to investigate human neuro-retina

Murali, Aparna, Ramlogan-Steel, Charmaine A., Andrzejewski, Slawomir, Steel, Jason C. and Layton, Christopher J. (2018). Retinal explant culture: a platform to investigate human neuro-retina. Clinical & Experimental Ophthalmology, 47 (2) ceo.13434, 274-285. doi: 10.1111/ceo.13434

Retinal explant culture: a platform to investigate human neuro-retina