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2024

Book Chapter

The role of the complement system in cancer etiology and management

Sonderegger, Stefan E., Manzanero, Silvia, Woodruff, Trent M., Farouqa, Jad, Nabizadeh, Jamileh, Panagides, Nadya and Rolfe, Barbara E. (2024). The role of the complement system in cancer etiology and management. Clinical immuno-oncology. (pp. 41-60.e10) edited by John E. Niederhuber. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-323-87763-3.00012-5

The role of the complement system in cancer etiology and management

2022

Journal Article

Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis

Ortiz-Espinosa, Sergio, Morales, Xabier, Senent, Yaiza, Alignani, Diego, Tavira, Beatriz, Macaya, Irati, Ruiz, Borja, Moreno, Haritz, Remírez, Ana, Sainz, Cristina, Rodriguez-Pena, Alejandro, Oyarbide, Alvaro, Ariz, Mikel, Andueza, Maria P., Valencia, Karmele, Teijeira, Alvaro, Hoehlig, Kai, Vater, Axel, Rolfe, Barbara, Woodruff, Trent M., Lopez-Picazo, Jose Maria, Vicent, Silvestre, Kochan, Grazyna, Escors, David, Gil-Bazo, Ignacio, Perez-Gracia, Jose Luis, Montuenga, Luis M., Lambris, John D., Ortiz de Solorzano, Carlos ... Pio, Ruben (2022). Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis. Cancer Letters, 529, 70-84. doi: 10.1016/j.canlet.2021.12.027

Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis

2022

Conference Publication

Immunoregulatory role for complement receptors in murine breast cancer

Rolfe, Barbara, Sonderegger, Stefan, McGirr, Crystal and Woodruff, Trent (2022). Immunoregulatory role for complement receptors in murine breast cancer. 28th Virtual International Complement Workshop (ICW) of the International-Complement-Society (ICS), Virtual, 6-10 December 2021. Oxford, United Kingdom: Elsevier.

Immunoregulatory role for complement receptors in murine breast cancer

2021

Journal Article

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

Gorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Lee, Han Siean, Rolfe, Barbara E., Woodruff, Trent M. and Clark, Richard J. (2021). Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. Journal of Medicinal Chemistry, 64 (22) acs.jmedchem.1c01174, 16598-16608. doi: 10.1021/acs.jmedchem.1c01174

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

2021

Journal Article

An immunoregulatory role for complement receptors in murine models of breast cancer

Akhir, Fazrena Nadia Md, Noor, Mohd Hezmee Mohd, Leong, Keith Weng Kit, Nabizadeh, Jamileh A., Manthey, Helga D., Sonderegger, Stefan E., Fung, Jenny Nga Ting, McGirr, Crystal E., Shiels, Ian A., Mills, Paul C., Woodruff, Trent M. and Rolfe, Barbara E. (2021). An immunoregulatory role for complement receptors in murine models of breast cancer. Antibodies, 10 (1) 2, 1-12. doi: 10.3390/antib10010002

An immunoregulatory role for complement receptors in murine models of breast cancer

2020

Journal Article

Correction to High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging

Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Wang, Wenqian, Ta, Hang Thu, Han, Yanxiao, Han, Felicity Y., Peng, Hui, Král, Petr, Rolfe, Barbara E., Gooding, J. Justin, Gaus, Katharina and Whittaker, Andrew K. (2020). Correction to High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging. ACS Nano, 14 (10), 14245-14246. doi: 10.1021/acsnano.0c07373

Correction to High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging

2020

Journal Article

Editorial: The Role of Complement in Tumors

Rolfe, Barbara E., Pio, Ruben, Woodruff, Trent M., Markiewski, Maciej M. and Manthey, Helga D. (2020). Editorial: The Role of Complement in Tumors. Frontiers in Immunology, 11 139, 139. doi: 10.3389/fimmu.2020.00139

Editorial: The Role of Complement in Tumors

2019

Journal Article

C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma

Nabizadeh, Jamileh A., Manthey, Helga D., Panagides, Nadya, Steyn, Frederik J., Lee, John D., Li, Xaria X., Akhir, Fazrena N. M., Chen, Weiyu, Boyle, Glen M., Taylor, Stephen M., Woodruff, Trent M. and Rolfe, Barbara E. (2019). C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma. FASEB Journal, 33 (10), fj201800980RR-11071. doi: 10.1096/fj.201800980rr

C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma

2019

Conference Publication

Complement C5a receptors, C5aR1 and C5aR2, mediate opposing pathologies in a mouse model of melanoma

Nabizadeh, J., Manthey, H., Panagides, N., Steyn, F., Lee, J., Li, X., Woodruff, T. and Rolfe, B. (2019). Complement C5a receptors, C5aR1 and C5aR2, mediate opposing pathologies in a mouse model of melanoma. 17th International Congress of Immunology (IUIS), Beijing, China, 19-23 October 2019. Weinheim, Germany: Wiley.

Complement C5a receptors, C5aR1 and C5aR2, mediate opposing pathologies in a mouse model of melanoma

2018

Journal Article

Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli

Chen, Weiyu, Zuo, Huali, Rolfe, Barbara, Schembri, Mark A., Cobbold, Rowland N., Zhang, Bing, Mahony, Timothy J. and Xu, Zhi Ping (2018). Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli. Journal of Controlled Release, 292, 196-209. doi: 10.1016/j.jconrel.2018.11.008

Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli

2018

Journal Article

The pathways for layered double hydroxide nanoparticles to enhance antigen (cross)-presentation on immune cells as adjuvants for protein vaccines

Yan, Shiyu, Xu, Kewei, Li, Li, Gu, Wenyi, Rolfe, Barbara E. and Xu, Zhi P. (2018). The pathways for layered double hydroxide nanoparticles to enhance antigen (cross)-presentation on immune cells as adjuvants for protein vaccines. Frontiers in Pharmacology, 9 (SEP) 1060, 1060. doi: 10.3389/fphar.2018.01060

The pathways for layered double hydroxide nanoparticles to enhance antigen (cross)-presentation on immune cells as adjuvants for protein vaccines

2018

Journal Article

Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles

Chen, Liyu, Glass, Joshua J., De Rose, Robert, Sperling, Claudia, Kent, Stephen J., Houston, Zachary H., Fletcher, Nicholas L., Rolfe, Barbara E. and Thurecht, Kristofer J. (2018). Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles. ACS Applied Bio Materials, 1 (3) acsabm.8b00220, 756-767. doi: 10.1021/acsabm.8b00220

Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles

2018

Journal Article

High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging

Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Wang, Wenqian, Ta, Hang Thu, Han, Yanxiao, Han, Felicity Y., Peng, Hui, Král, Petr, Rolfe, Barbara E., Gooding, John Justin, Gaus, Katharina and Whittaker, Andrew Keith (2018). High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging. ACS Nano, 12 (9) acsnano.8b03726, 9162-9176. doi: 10.1021/acsnano.8b03726

High F-content perfluoropolyether-based nanoparticles for targeted detection of breast cancer by 19F magnetic resonance and optical imaging

2018

Journal Article

Clay nanoparticles elicit long-term immune responses by forming biodegradable depots for sustained antigen stimulation

Chen, Weiyu, Zuo, Huali, Li, Bei, Duan, Chengcheng, Rolfe, Barbara, Zhang, Bing, Mahony, Timothy J and Xu, Zhi Ping (2018). Clay nanoparticles elicit long-term immune responses by forming biodegradable depots for sustained antigen stimulation. Small, 14 (19) 1704465, e1704465. doi: 10.1002/smll.201704465

Clay nanoparticles elicit long-term immune responses by forming biodegradable depots for sustained antigen stimulation

2018

Journal Article

Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction

Fanning, Jonathon P., See Hoe, Louise E., Passmore, Margaret R., Barnett, Adrian G., Rolfe, Barbara E., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky and Fraser, John F. (2018). Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction. Therapeutic Advances in Neurological Disorders, 11, 1756286418759493. doi: 10.1177/1756286418759493

Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction

2018

Conference Publication

High F-Content Perfluoropolyether-based Polymers for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging

Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Ta, Hang T., Han, Yanxiao, Han, Felicity Y., Peng, Hui, Král, Petr, Rolfe, Barbara E. and Whittaker, Andrew K. (2018). High F-Content Perfluoropolyether-based Polymers for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging. World Polymer Congress Macro 2018, Cairns QLD Australia, 1-5 July 2018.

High F-Content Perfluoropolyether-based Polymers for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging

2017

Journal Article

High adjuvant activity of layered double hydroxide nanoparticles and nanosheets in anti-tumour vaccine formulations

Yan, Shiyu, Gu, Wenyi, Zhang, Bing, Rolfe, Barbara E and Xu, Zhi Ping (2017). High adjuvant activity of layered double hydroxide nanoparticles and nanosheets in anti-tumour vaccine formulations. Dalton Transactions, 47 (9), 2956-2964. doi: 10.1039/c7dt03725b

High adjuvant activity of layered double hydroxide nanoparticles and nanosheets in anti-tumour vaccine formulations

2017

Journal Article

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice

Chen, Liyu, Simpson, Joshua D, Fuchs, Adrian V, Rolfe, Barbara E and Thurecht, Kristofer J (2017). Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice. Molecular pharmaceutics, 14 (12), 4485-4497. doi: 10.1021/acs.molpharmaceut.7b00611

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice

2017

Journal Article

Layered double hydroxide nanoparticles: Impact on vascular cells, blood cells and the complement system

Gu, Zi, Yan, Shiyu, Cheong, Soshan, Cao, Zhenbang, Zuo, Huali, Thomas, Anita C., Rolfe, Barbara E. and Xu, Zhi Ping (2017). Layered double hydroxide nanoparticles: Impact on vascular cells, blood cells and the complement system. Journal of Colloid and Interface Science, 512, 404-410. doi: 10.1016/j.jcis.2017.10.069

Layered double hydroxide nanoparticles: Impact on vascular cells, blood cells and the complement system

2017

Journal Article

Efficient induction of comprehensive immune responses to control pathogenic E. coli by clay nano-adjuvant with the moderate size and surface charge

Chen, Weiyu, Zuo, Huali, Mahony, Timothy J, Zhang, Bing, Rolfe, Barbara and Xu, Zhi Ping (2017). Efficient induction of comprehensive immune responses to control pathogenic E. coli by clay nano-adjuvant with the moderate size and surface charge. Scientific reports, 7 (1) 13367, 1-12. doi: 10.1038/s41598-017-13570-2

Efficient induction of comprehensive immune responses to control pathogenic E. coli by clay nano-adjuvant with the moderate size and surface charge