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2017

Journal Article

Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

Gibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather, Taylor, Steven L., Leong, Lex E. X., Rogers, Geraint B. and Simpson, Jodie L. (2017). Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. The Lancet, 390 (10095), 659-668. doi: 10.1016/S0140-6736(17)31281-3

Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

2017

Journal Article

Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit

Hukins, Craig, Wong, Mimi, Murphy, Michelle and Upham, John (2017). Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit. Internal Medicine Journal, 47 (7), 784-792. doi: 10.1111/imj.13403

Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit

2017

Journal Article

Bronchiectasis in children: current concepts in immunology and microbiology

Pizzutto, Susan J., Hare, Kim M. and Upham, John W. (2017). Bronchiectasis in children: current concepts in immunology and microbiology. Frontiers in Pediatrics, 5 123, 123. doi: 10.3389/fped.2017.00123

Bronchiectasis in children: current concepts in immunology and microbiology

2017

Journal Article

Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

Taylor, Steven L., Leong, Lex E. X., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B., Gibson, Peter G., Simpson, Jodie L. and Rogers, Geraint B. (2017). Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology. Journal of Allergy and Clinical Immunology, 141 (1), 94-103.e15. doi: 10.1016/j.jaci.2017.03.044

Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

2017

Journal Article

Can biomarkers help us hit targets in difficult-to-treat asthma?

Fricker, Michael, Heaney, Liam G. and Upham, John W. (2017). Can biomarkers help us hit targets in difficult-to-treat asthma?. Respirology, 22 (3), 430-442. doi: 10.1111/resp.13014

Can biomarkers help us hit targets in difficult-to-treat asthma?

2017

Journal Article

Response

Wurzel, Danielle F., Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W. and Chang, Anne B. (2017). Response. Chest, 151 (4), 940-941. doi: 10.1016/j.chest.2016.12.030

Response

2017

Journal Article

Dendritic cells in human lung disease: recent advances

Upham, John W. and Xi, Yang (2017). Dendritic cells in human lung disease: recent advances. Chest, 151 (3), 668-673. doi: 10.1016/j.chest.2016.09.030

Dendritic cells in human lung disease: recent advances

2017

Journal Article

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

Arikkatt, Jaisy, Ullah, Md Ashik, Short, Kirsty Renfree, Zhang, Vivian, Gan, Wan Jun, Loh, Zhixuan, Werder, Rhiannon B., Simpson, Jennifer, Sly, Peter D., Mazzone, Stuart B., Spann, Kirsten M., Ferreira, Manuel A R., Upham, John W., Sukkar, Maria B. and Phipps, Simon (2017). RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma. eLife, 6 e21199. doi: 10.7554/eLife.21199

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

2016

Journal Article

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network

Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Irving, Louis B., Korman, Tony M., Senenayake, Sanjaya, Macartney, Kristine K., Blyth, Christopher C., Brown, Simon, Waterer, Grant, Hewer, Robert, Friedman, N Deborah, Wark, Peter A., Simpson, Graham, Upham, John, Bowler, Simon D., Lessing, Albert, Kotsimbos, Tom and Kelly, Paul M. (2016). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network. Communicable Diseases Intelligence Quarterly Report, 40 (4), E521-E526. doi: 10.33321/cdi.2016.40.59

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network

2016

Journal Article

Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis

Wurzel, Danielle F., Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W., Petsky, Helen L., Smith-Vaughan, Heidi, Masters, Brent, Buntain, Helen and Chang, Anne B. (2016). Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis. Chest, 150 (5), 1101-1108. doi: 10.1016/j.chest.2016.06.030

Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis

2016

Journal Article

Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria

Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., Guo, M., Reddel, H. K., Jenkins, C., Marks, G. B., Thien, F., Rimmer, J., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Wright, C., Bint, M., Yozghatlian, V., Burgess, S., Sivakumaran, P., Yan, K. Y., Kritikos, V., Peters, M., Baraket, M., Aminazad, A., Robinson, P., Jaffe, A. ... Gibson, P. G. (2016). Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria. Clinical and Experimental Allergy, 46 (11), 1407-1415. doi: 10.1111/cea.12774

Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria

2016

Journal Article

Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity

Lynch, Jason P., Werder, Rhiannon B., Simpson, Jennifer, Loh, Zhixuan, Zhang, Vivian, Haque, Ashraful, Spann, Kirsten, Sly, Peter D., Mazzone, Stuart B., Upham, John W. and Phipps, Simon (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity. Journal of Allergy and Clinical Immunology, 138 (5), 1326-1337. doi: 10.1016/j.jaci.2016.02.039

Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity

2016

Journal Article

Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

Navarro, Severine, Pickering, Darren A., Ferreira, Ivana B., Jones, Linda, Ryan, Stephanie, Troy, Sally, Leech, Andrew, Hotez, Peter J., Zhan, Bin, Laha, Thewarach, Prentice, Roger, Sparwasser, Tim, Croese, John, Engwerda, Christian R., Upham, John W., Julia, Valerie, Giacomin, Paul R. and Loukas, Alex (2016). Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine, 8 (362) 362ra143, 362ra143-362ra143. doi: 10.1126/scitranslmed.aaf8807

Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

2016

Journal Article

Understanding the immune and inflammatory response to rhinoviruses: recent advances with relevance to asthma

Kunarajah, Kuhan, Pena, Olga and Upham, John W. (2016). Understanding the immune and inflammatory response to rhinoviruses: recent advances with relevance to asthma. Current Respiratory Medicine Reviews, 12 (3), 215-224. doi: 10.2174/1573398X12666160909102919

Understanding the immune and inflammatory response to rhinoviruses: recent advances with relevance to asthma

2016

Journal Article

Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the influenza complications alert network (FluCAN)

Blyth, C. C., Macartney, K. K., Hewagama, S., Senenayake, S., Friedman, N. D., Simpson, G., Upham, J., Kotsimbos, T., Kelly, P. and Cheng, A. C. (2016). Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the influenza complications alert network (FluCAN). Eurosurveillance, 21 (30), 25-33. doi: 10.2807/1560-7917.ES.2016.21.30.30301

Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the influenza complications alert network (FluCAN)

2016

Journal Article

Identification of STOML2 as a putative novel asthma risk gene associated with IL6R

Revez, J. A., Matheson, M. C., Hui, J., Baltic, S., James, A., Upham, J. W., Dharmage, S., Thompson, P. J., Martin, N. G., Hopper, J. L. and Ferreira, M. A. R. (2016). Identification of STOML2 as a putative novel asthma risk gene associated with IL6R. Allergy, 71 (7), 1020-1030. doi: 10.1111/all.12869

Identification of STOML2 as a putative novel asthma risk gene associated with IL6R

2016

Journal Article

Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype

Scott, H. A., Gibson, P. G., Garg, M. L., Upham, J. W. and Wood, L. G. (2016). Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype. Allergy, 71 (7), 1037-1047. doi: 10.1111/all.12891

Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype

2016

Journal Article

Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry

Gibson, P. G., Reddel, H., McDonald, V. M., Marks, G., Jenkins, C., Gillman, A., Upham, J., Sutherland, M., Rimmer, J., Thien, F., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Robinson, P., Wright, C., Yozghatlian, V., Burgess, S., Sivakumaran, P., Jaffe, A., Bowden, J., Wark, P. A., Yan, K. Y., Kritikos, V., Peters, M., Hew, M., Aminazad, A. ... Guo, M. (2016). Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry. Internal Medicine Journal, 46 (9), 1054-1062. doi: 10.1111/imj.13166

Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry

2016

Journal Article

Periostin levels and eosinophilic inflammation in poorly-controlled asthma

Simpson, Jodie L., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Jia, Guiquan, Holweg, Cecile T. J. and Gibson, Peter G. (2016). Periostin levels and eosinophilic inflammation in poorly-controlled asthma. BMC Pulmonary Medicine, 16 (1) 67, 67.1-67.7. doi: 10.1186/s12890-016-0230-4

Periostin levels and eosinophilic inflammation in poorly-controlled asthma

2016

Journal Article

Combination long acting bronchodilators for COPD

Upham, John W. and Gleeson, Sarah J. (2016). Combination long acting bronchodilators for COPD. Medicine Today, 17 (4), 73-74.

Combination long acting bronchodilators for COPD