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2016

Journal Article

CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites

Irvine, Katharine M., Xuan Banh, Gadd, Victoria L., Wojcik, Kyle K., Ariffin, Juliana K., Jose, Sara, Lukowski, Samuel, Baillie, Gregory J., Sweet, Matthew J. and Powell, Elizabeth E. (2016). CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites. JCI Insight, 1 (8) e86914, e86914. doi: 10.1172/jci.insight.86914

CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites

2016

Journal Article

Liver-related mortality in countries of the developed world: an ecological study approach to explain the variability

von Wulffen, M., Clark, P. J., Macdonald, G. A., Raj, A. S., Kendall, B. J., Powell, E. E., Jones, M. P. and Holtmann, G. (2016). Liver-related mortality in countries of the developed world: an ecological study approach to explain the variability. Alimentary Pharmacology and Therapeutics, 44 (1), 68-77. doi: 10.1111/apt.13657

Liver-related mortality in countries of the developed world: an ecological study approach to explain the variability

2016

Journal Article

Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease

El-Atem, N. A., Wojcik, K., Horsfall, L., Irvine, K. M., Johnson, T., McPhail, S. M. and Powell, E. E. (2016). Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease. Internal Medicine Journal, 46 (4), 420-426. doi: 10.1111/imj.13008

Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease

2016

Journal Article

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

Melino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

2016

Journal Article

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

Ramnath, Divya, Powell, Elizabeth E., Scholz, Glen M. and Sweet, Matthew J. (2016). The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair. Seminars in Cell and Developmental Biology, 61, 22-30. doi: 10.1016/j.semcdb.2016.08.014

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

2015

Journal Article

Can paracetamol (acetaminophen) be administered to patients with liver impairment?

Hayward, Kelly L., Powell, Elizabeth E., Irvine, Katharine M. and Martin, Jennifer H. (2015). Can paracetamol (acetaminophen) be administered to patients with liver impairment?. British Journal of Clinical Pharmacology, 81 (2), 210-222. doi: 10.1111/bcp.12802

Can paracetamol (acetaminophen) be administered to patients with liver impairment?

2015

Journal Article

FibroGENE: A gene-based model for staging liver fibrosis

Eslam, Mohammed, Hashem, Ahmed M., Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J., Mangia, Alessandra, Chan, Henry Lik Yuen, Irving, William L., Sheridan, David, Abate, Maria Lorena, Adams, Leon A., Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Nattermann, Jacob, Riordan, Stephen, Miele, Luca, Kelaeng, Kebitsaone Simon, Ampuero, Jacob, Ahlenstiel, Golo, McLeod, Duncan, Powell, Elizabeth, Liddle, Christopher, Douglas, Mark W., Booth, David R. and George, Jacob (2015). FibroGENE: A gene-based model for staging liver fibrosis. Journal of Hepatology, 64 (2), 390-398. doi: 10.1016/j.jhep.2015.11.008

FibroGENE: A gene-based model for staging liver fibrosis

2015

Journal Article

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

2015

Journal Article

The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease

Irvine, Katharine M., Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin J., Horsfall, Leigh U., Fletcher, Linda M., Ungerer, Jacobus P. J., Pretorius, Carel J., Miller, Gregory C., Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease. Liver International, 36 (3), 370-377. doi: 10.1111/liv.12896

The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease

2015

Journal Article

Response to ELF cut-off points: aetiology is also a relevant factor

Powell, Elizabeth E., Irvine, Katharine M., Fagan, Kevin J., Ballard, Emma and O'Rourke, Peter (2015). Response to ELF cut-off points: aetiology is also a relevant factor. Liver International, 35 (7), 1921-1921. doi: 10.1111/liv.12822

Response to ELF cut-off points: aetiology is also a relevant factor

2015

Journal Article

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

Fagan, Kevin J., Pretorius, Carel J., Horsfall, Leigh U., Irvine, Katharine M., Wilgen, Urs, Choi, Kihoon, Fletcher, Linda M., Tate, Jill, Melino, Michelle, Nusrat, Sharmin, Miller, Gregory C., Clouston, Andrew D., Ballard, Emma, O'Rourke, Peter, Lampe, Guy, Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2015). ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. Liver International, 35 (6), 1673-1681. doi: 10.1111/liv.12760

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

2015

Journal Article

Systematic review: unmet supportive care needs in people diagnosed with chronic liver disease

Valery, Patricia C., Powell, Elizabeth, Moses, Neta, Volk, Michael L., McPhail, Steven M., Clark, Paul J. and Martin, Jennifer (2015). Systematic review: unmet supportive care needs in people diagnosed with chronic liver disease. BMJ Open, 5 (4) e007451, 1-16. doi: 10.1136/bmjopen-2014-007451

Systematic review: unmet supportive care needs in people diagnosed with chronic liver disease

2015

Journal Article

Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection

Fagan, Kevin J., Rogers, Geraint B., Melino, Michelle, Arthur, Dionne M., Costello, Mary-Ellen, Morrison, Mark, Powell, Elizabeth E. and Irvine, Katharine M. (2015). Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection. PLoS One, 10 (3) e0120642, e0120642. doi: 10.1371/journal.pone.0120642

Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection

2015

Journal Article

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

Eslam, Mohammed, Hashem, Ahmed M, Leung, Reynold, Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J, Chan, Henry L.K, Irving, William L, Sheridan, David, Abate, Maria L, Adams, Leon A, Mangia, Alessandra, Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Powell, Elizabeth, Nattermann, Jacob, Riordan, Stephen, McLeod, Duncan, Armstrong, Nicola J, Douglas, Mark W, Liddle, Christopher, Booth, David R, George, Jacob, Ahlenstiel, Golo ... Santaro, Rosanna (2015). Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nature Communications, 6 (6422) 6422. doi: 10.1038/ncomms7422

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

2014

Journal Article

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

2014

Journal Article

Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?

Fagan, K. J., Zhao, Eileen Y., Horsfall, L. U., Ruffin, Brittany J., Kruger, Mark S., McPhail, S. M., O'Rourke, Peter, Ballard, Emma, Irvine, K. M. and Powell, E. E. (2014). Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?. Internal Medicine Journal, 44 (9), 865-872. doi: 10.1111/imj.12491

Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?

2014

Journal Article

Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers

Fagan K.J., Irvine K.M., McWhinney B.C., Fletcher L.M., Horsfall L.U., Johnson L., O'Rourke P., Martin J., Scott I., Pretorius C.J., Ungerer J.P.J. and Powell E.E. (2014). Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers. BMC Gastroenterology, 14 (1) 97, 1-6. doi: 10.1186/1471-230X-14-97

Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers

2014

Journal Article

The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease

Gadd, Victoria L., Skoien, Richard, Powell, Elizabeth E., Fagan, Kevin J., Winterford, Clay, Horsfall, Leigh, Irvine, Katharine and Clouston, Andrew D. (2014). The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease. Hepatology, 59 (4), 1393-1405. doi: 10.1002/hep.26937

The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease

2014

Journal Article

New paradigms in the histopathology of NAFLD

Clouston, Andrew D., Gadd, Victoria L., Irvine, Katharine M. and Powell, Elizabeth E. (2014). New paradigms in the histopathology of NAFLD. Current Hepatitis Reports, 13 (2), 81-87. doi: 10.1007/s11901-014-0214-x

New paradigms in the histopathology of NAFLD

2013

Journal Article

BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient Transferrin

Fagan, Kevin J., Irvine, Katharine M., McWhinney, Brett C., Fletcher, Linda M., Horsfall, Leigh U., Johnson, Lambro A., Clouston, Andrew D., Jonsson, Julie R., O'Rourke, Peter, Martin, Jennifer, Pretorius, Carel J., Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2013). BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient Transferrin. Alcoholism Clinical and Experimental Research, 37 (10), 1771-1778. doi: 10.1111/acer.12143

BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient Transferrin