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2017

Journal Article

Patient-oriented education and medication management intervention for people with decompensated cirrhosis: study protocol for a randomized controlled trial

Hayward, Kelly L., Martin, Jennifer H., Cottrell, W. Neil, Karmakar, Antara, Horsfall, Leigh U., Patel, Preya J., Smith, David D., Irvine, Katharine M., Powell, Elizabeth E. and Valery, Patricia C. (2017). Patient-oriented education and medication management intervention for people with decompensated cirrhosis: study protocol for a randomized controlled trial. Trials, 18 (1) 339, 339. doi: 10.1186/s13063-017-2075-4

Patient-oriented education and medication management intervention for people with decompensated cirrhosis: study protocol for a randomized controlled trial

2017

Journal Article

Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia

Valery, Patricia C., Clark, Paul J., McPhail, Steven M., Rahman, Tony, Hayward, Kelly, Martin, Jennifer, Horsfall, Leigh, Volk, Michael L., Skoien, Richard and Powell, Elizabeth (2017). Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia. Internal Medicine Journal, 47 (4), 429-435. doi: 10.1111/imj.13380

Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia

2017

Journal Article

Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study

Nicoletti, Paola, Aithal, Guruprasad P., Bjornsson, Einar S., Andrade, Raul J. A, Sawle, Ashley, Arrese, Marco, Barnhart, Huiman X., Bondon-Guitton, Emmanuelle, Hayashi, Paul H., Bessone, Fernando, Carvajal, Alfonso, Cascorbi, Ingolf, Cirulli, Elizabeth T., Chalasani, Naga, Conforti, Anita, Coulthard, Sally A., Daly, Mark J., Day, Christopher P., Dillon, John F., Fontana, Robert J., Grove, Jane I., Hallberg, Pär, Hernandez, Nelia, Ibanez, Luisa, Kullak-Ublick, Gerd A., Laitinen, Tarja, Larrey, Dominique, Lucena, M. Isabel, Maitland-van der Zee, Anke H. ... Daly, Ann K. (2017). Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study. Gastroenterology, 152 (5), 1078-1089. doi: 10.1053/j.gastro.2016.12.016

Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study

2017

Journal Article

IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis

Eslam, Mohammed, McLeod, Duncan, Kelaeng, Kebitsaone Simon, Mangia, Alessandra, Berg, Thomas, Thabet, Khaled, Irving, William L., Dore, Gregory J., Sheridan, David, Gronbaek, Henning, Abate, Maria Lorena, Hartmann, Rune, Bugianesi, Elisabetta, Spengler, Ulrich, Rojas, Angela, Booth, David R., Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Mahajan, Hema, Fischer, Janett, Nattermann, Jacob, Douglas, Mark W., Liddle, Christopher, Powell, Elizabeth, Romero-Gomez, Manuel and George, Jacob (2017). IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis. Nature Genetics, 49 (5), 795-800. doi: 10.1038/ng.3836

IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis

2017

Conference Publication

Enhanced Liver Fibrosis test and liver stiffness measurements identify high prevalence of advanced fibrosis in people with type 2 diabetes

Patel, P. J., Stuart, K. A., Horsfall, L. U., Hayward, K. L., Hossain, F., Williams, S., Johnson, T., Brown, N., Lampe, G., Buck, L., Saad, N., Clouston, A., Irvine, K. M., Russell, A., Valery, P. C. and Powell, E. E. (2017). Enhanced Liver Fibrosis test and liver stiffness measurements identify high prevalence of advanced fibrosis in people with type 2 diabetes. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD Australia, 20 - 22 August 2017. Richmond, VIC Australia: Wiley-Blackwell.

Enhanced Liver Fibrosis test and liver stiffness measurements identify high prevalence of advanced fibrosis in people with type 2 diabetes

2017

Conference Publication

Can modest alcohol intake be dismissed as a co-factor in diabetic patients with non-alcoholic fatty liver disease?

Patel, P. J., Smith, D. D., Stuart, K. A., Horsfall, L. U., Hayward, K. L., Hossain, F., Williams, S., Johnson, T., Brown, N. N., Saad, N., Clouston, A. D., Irvine, K. M., Russell, A. W., Valery, P. C. and Powell, E. E. (2017). Can modest alcohol intake be dismissed as a co-factor in diabetic patients with non-alcoholic fatty liver disease?. International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Amsterdam, Netherlands, 19-23 April 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0168-8278(17)31602-1

Can modest alcohol intake be dismissed as a co-factor in diabetic patients with non-alcoholic fatty liver disease?

2016

Journal Article

Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers

Irvine, Katharine M., Wockner, Leesa F., Hoffmann, Isabel, Horsfall, Leigh U., Fagan, Kevin J., Bijin, Veonice, Lee, Bernett, Clouston, Andrew D., Lampe, Guy, Connolly, John E. and Powell, Elizabeth E. (2016). Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers. PLoS ONE, 11 (11) 167001, e0167001. doi: 10.1371/journal.pone.0167001

Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers

2016

Journal Article

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C

Thabet, Khaled, Asimakopoulos, Anastasia, Shojaei, Maryam, Romero-Gomez, Manuel, Mangia, Alessandra, Irving, William L., Berg, Thomas, Dore, Gregory J., Gronbaek, Henning, Sheridan, David, Abate, Maria Lorena, Bugianesi, Elisabetta, Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Fischer, Janett, Spengler, Ulrich, Nattermann, Jacob, Wahid, Ahmed, Rojas, Angela, White, Rose, Douglas, Mark W., McLeod, Duncan, Powell, Elizabeth, Liddle, Christopher, Van Der Poorten, David, George, Jacob, Eslam, Mohammed ... Santaro, Rosanna (2016). MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C. Nature Communications, 7 (1) 12757, 12757. doi: 10.1038/ncomms12757

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C

2016

Journal Article

Prevalence of medication discrepancies in patients with cirrhosis: A pilot study

Hayward, Kelly L., Valery, Patricia C., Cottrell, W. Neil, Irvine, Katharine M., Horsfall, Leigh U., Tallis, Caroline J., Chachay, Veronique S., Ruffin, Brittany J., Martin, Jennifer H. and Powell, Elizabeth E. (2016). Prevalence of medication discrepancies in patients with cirrhosis: A pilot study. BMC Gastroenterology, 16 (1) 114, 114. doi: 10.1186/s12876-016-0530-4

Prevalence of medication discrepancies in patients with cirrhosis: A pilot study

2016

Journal Article

Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes

Eslam, Mohammed, Mangia, Alessandra, Berg, Thomas, Chan, Henry Lik Yuen, Irving, William L., Dore, Gregory J., Abate, Maria Lorena, Bugianesi, Elisabetta, Adams, Leon A., Najim, Mustafa A. M., Miele, Luca, Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Fischer, Janett, Romero-Gomez, Manuel, Spengler, Ulrich, Nattermann, Jacob, Rahme, Antony, Sheridan, David, Booth, David R., Mcleod, Duncan, Powell, Elizabeth, Liddle, Christopher, Douglas, Mark W., van der Poorten, Dvaid and George, Jacob (2016). Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes. Hepatology, 64 (1), 34-46. doi: 10.1002/hep.28475

Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes

2016

Journal Article

Altered peripheral blood monocyte phenotype and function in chronic liver disease: implications for hepatic recruitment and systemic inflammation

Gadd, Victoria L., Patel, Preya J., Jose, Sara, Horsfall, Leigh, Powell, Elizabeth E. and Irvine, Katharine M. (2016). Altered peripheral blood monocyte phenotype and function in chronic liver disease: implications for hepatic recruitment and systemic inflammation. PLoS One, 11 (6) e0157771, e0157771. doi: 10.1371/journal.pone.0157771

Altered peripheral blood monocyte phenotype and function in chronic liver disease: implications for hepatic recruitment and systemic inflammation

2016

Journal Article

CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites

Irvine, Katharine M., Xuan Banh, Gadd, Victoria L., Wojcik, Kyle K., Ariffin, Juliana K., Jose, Sara, Lukowski, Samuel, Baillie, Gregory J., Sweet, Matthew J. and Powell, Elizabeth E. (2016). CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites. JCI Insight, 1 (8) e86914, e86914. doi: 10.1172/jci.insight.86914

CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites

2016

Journal Article

Liver-related mortality in countries of the developed world: an ecological study approach to explain the variability

von Wulffen, M., Clark, P. J., Macdonald, G. A., Raj, A. S., Kendall, B. J., Powell, E. E., Jones, M. P. and Holtmann, G. (2016). Liver-related mortality in countries of the developed world: an ecological study approach to explain the variability. Alimentary Pharmacology and Therapeutics, 44 (1), 68-77. doi: 10.1111/apt.13657

Liver-related mortality in countries of the developed world: an ecological study approach to explain the variability

2016

Journal Article

Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease

El-Atem, N. A., Wojcik, K., Horsfall, L., Irvine, K. M., Johnson, T., McPhail, S. M. and Powell, E. E. (2016). Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease. Internal Medicine Journal, 46 (4), 420-426. doi: 10.1111/imj.13008

Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease

2016

Journal Article

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

Melino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

2016

Journal Article

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

Ramnath, Divya, Powell, Elizabeth E., Scholz, Glen M. and Sweet, Matthew J. (2016). The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair. Seminars in Cell and Developmental Biology, 61, 22-30. doi: 10.1016/j.semcdb.2016.08.014

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

2016

Conference Publication

Medication adherence in outpatients with decompensated cirrhosis

Hayward, K. L., Cottrell, W. N., Karmakar, A., Patel, P. J., Horsfall, L. U., Martin, J. H., Irvine, K. M., Tallis, C. J., Wright, P. L., Stuart, K. A., Valery, P. C. and Powell, E. E. (2016). Medication adherence in outpatients with decompensated cirrhosis. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, SA Australia, 10–12 October 2016. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/jgh.13520

Medication adherence in outpatients with decompensated cirrhosis

2016

Conference Publication

Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes

Patel, P. J., Stuart, K. A., Horsfall, L. U., Hossain, F., Williams, S., Johnson, T., Brown, N., Lampe, G., Buck, L., Clouston, A., Irvine, K. M., Russell, A. and Powell, E. E. (2016). Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October, 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13520

Non-invasive markers indicate a high prevalence of advanced fibrosis in adults with type 2 diabetes

2015

Journal Article

Can paracetamol (acetaminophen) be administered to patients with liver impairment?

Hayward, Kelly L., Powell, Elizabeth E., Irvine, Katharine M. and Martin, Jennifer H. (2015). Can paracetamol (acetaminophen) be administered to patients with liver impairment?. British Journal of Clinical Pharmacology, 81 (2), 210-222. doi: 10.1111/bcp.12802

Can paracetamol (acetaminophen) be administered to patients with liver impairment?

2015

Journal Article

FibroGENE: A gene-based model for staging liver fibrosis

Eslam, Mohammed, Hashem, Ahmed M., Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J., Mangia, Alessandra, Chan, Henry Lik Yuen, Irving, William L., Sheridan, David, Abate, Maria Lorena, Adams, Leon A., Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Nattermann, Jacob, Riordan, Stephen, Miele, Luca, Kelaeng, Kebitsaone Simon, Ampuero, Jacob, Ahlenstiel, Golo, McLeod, Duncan, Powell, Elizabeth, Liddle, Christopher, Douglas, Mark W., Booth, David R. and George, Jacob (2015). FibroGENE: A gene-based model for staging liver fibrosis. Journal of Hepatology, 64 (2), 390-398. doi: 10.1016/j.jhep.2015.11.008

FibroGENE: A gene-based model for staging liver fibrosis