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2019

Journal Article

Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis

Yang, Yoon Mee, Noureddin, Mazen, Liu, Cheng, Ohashi, Koichiro, Kim, So Yeon, Ramnath, Divya, Powell, Elizabeth E., Sweet, Matthew J., Roh, Yoon Seok, Hsin, I-Fang, Deng, Nan, Liu, Zhenqiu, Liang, Jiurong, Mena, Edward, Shouhed, Daniel, Schwabe, Robert F., Jiang, Dianhua, Lu, Shelly C., Noble, Paul W. and Seki, Ekihiro (2019). Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Science Translational Medicine, 11 (496) eaat9284, eaat9284. doi: 10.1126/scitranslmed.aat9284

Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis

2019

Journal Article

Engaging primary care clinicians in the assessment of NAFLD

Valery, Patricia C. and Powell, Elizabeth E. (2019). Engaging primary care clinicians in the assessment of NAFLD. Nature Reviews Gastroenterology and Hepatology, 16 (8), 458-460. doi: 10.1038/s41575-019-0164-4

Engaging primary care clinicians in the assessment of NAFLD

2019

Journal Article

Increasing hospitalization rates for cirrhosis: overrepresentation of disadvantaged Australians

Powell, Elizabeth E., Skoien, Richard, Rahman, Tony, Clark, Paul J., O'Beirne, James, Hartel, Gunter, Stuart, Katherine A., McPhail, Steven M., Gupta, Rohit, Boyd, Peter and Valery, Patricia C. (2019). Increasing hospitalization rates for cirrhosis: overrepresentation of disadvantaged Australians. EClinicalMedicine, 11, 44-53. doi: 10.1016/j.eclinm.2019.05.007

Increasing hospitalization rates for cirrhosis: overrepresentation of disadvantaged Australians

2019

Conference Publication

Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation

Iyer, Abishek, Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J. and Fairlie, David P. (2019). Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation. Experimental Biology Meeting (EB), Orlando Fl, Apr 06-09, 2019. HOBOKEN: WILEY.

Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation

2019

Journal Article

Medication‐related problems in outpatients with decompensated cirrhosis: Opportunities for harm prevention

Hayward, Kelly L., Patel, Preya J., Valery, Patricia C., Horsfall, Leigh U., Li, Catherine Y., Wright, Penny L., Tallis, Caroline J., Stuart, Katherine A., Irvine, Katharine M., Cottrell, W. Neil, Martin, Jennifer H. and Powell, Elizabeth E. (2019). Medication‐related problems in outpatients with decompensated cirrhosis: Opportunities for harm prevention. Hepatology Communications, 3 (5) hep4.1334, 620-631. doi: 10.1002/hep4.1334

Medication‐related problems in outpatients with decompensated cirrhosis: Opportunities for harm prevention

2019

Journal Article

Causes and consequences of innate immune dysfunction in cirrhosis

Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Causes and consequences of innate immune dysfunction in cirrhosis. Frontiers in Immunology, 10 (FEB) 293, 293. doi: 10.3389/fimmu.2019.00293

Causes and consequences of innate immune dysfunction in cirrhosis

2019

Journal Article

A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms

Sharkawy, Rasha El, Bayoumi, Ali, Metwally, Mayada, Mangia, Alessandra, Berg, Thomas, Romero-Gomez, Manuel, Abate, Maria Lorena, Irving, William L., Sheridan, David, Dore, Gregory J., Spengler, Ulrich, Lampertico, Pietro, Bugianesi, Elisabetta, Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Santoro, Rosanna, Gallego-Durán, Rocío, Fischer, Janett, Nattermann, Jacob, D’Ambrosio, Roberta, McLeod, Duncan, Powell, Elizabeth, latchoumanin, Olivier, Thabet, Khaled, Najim, Mustafa A. M., Douglas, Mark W., Liddle, Christopher ... Jonsson, Julie R. (2019). A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms. Scientific Reports, 9 (1) 1439, 1439. doi: 10.1038/s41598-018-35736-2

A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms

2019

Journal Article

Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)

Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293). Frontiers in Immunology, 10 (APR) 818, 818. doi: 10.3389/fimmu.2019.00818

Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)

2018

Journal Article

Weight based tacrolimus trough concentrations post liver transplant

Liu, Zheng, Cheng, Jeffrey, Powell, Elizabeth, Macdonald, Graeme, Fawcett, Jonathan, Lynch, Stephen and Martin, Jennifer (2018). Weight based tacrolimus trough concentrations post liver transplant. Internal Medicine Journal, 49 (1), 79-83. doi: 10.1111/imj.14043

Weight based tacrolimus trough concentrations post liver transplant

2018

Journal Article

Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control

Patel, Preya Janubhai, Hossain, Fabrina, Horsfall, Leigh Ula, Banh, Xuan, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Clouston, Andrew Donald, Stuart, Katherine Anne, Russell, Anthony William and Powell, Elizabeth Ellen (2018). Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control. Journal of Diabetes and its Complications, 32 (8), 799-804. doi: 10.1016/j.jdiacomp.2018.05.008

Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control

2018

Journal Article

Haemochromatosis: a clinical update for the practising physician

Radford-Smith, Daniel E., Powell, Elizabeth E. and Powell, Lawrie W. (2018). Haemochromatosis: a clinical update for the practising physician. Internal Medicine Journal, 48 (5), 509-516. doi: 10.1111/imj.13784

Haemochromatosis: a clinical update for the practising physician

2018

Conference Publication

Advanced fibrosis is associated with longitudinal increases in Fibrosis-4 and NAFLD fibrosis scores

Patel, Preya, Cheng, Johnson Chieh-Yu, Banh, Xuan, Hossain, Fabrina, Horsfall, Leigh Ula, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine A., Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine, Clouston, Andrew D., Bernard, Anne and Powell, Elizabeth E. (2018). Advanced fibrosis is associated with longitudinal increases in Fibrosis-4 and NAFLD fibrosis scores. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, CA United States, 9-13 November 2018. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/hep.30257

Advanced fibrosis is associated with longitudinal increases in Fibrosis-4 and NAFLD fibrosis scores

2017

Journal Article

Patient-oriented education and medication management intervention for people with decompensated cirrhosis: study protocol for a randomized controlled trial

Hayward, Kelly L., Martin, Jennifer H., Cottrell, W. Neil, Karmakar, Antara, Horsfall, Leigh U., Patel, Preya J., Smith, David D., Irvine, Katharine M., Powell, Elizabeth E. and Valery, Patricia C. (2017). Patient-oriented education and medication management intervention for people with decompensated cirrhosis: study protocol for a randomized controlled trial. Trials, 18 (1) 339, 339. doi: 10.1186/s13063-017-2075-4

Patient-oriented education and medication management intervention for people with decompensated cirrhosis: study protocol for a randomized controlled trial

2017

Journal Article

Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia

Valery, Patricia C., Clark, Paul J., McPhail, Steven M., Rahman, Tony, Hayward, Kelly, Martin, Jennifer, Horsfall, Leigh, Volk, Michael L., Skoien, Richard and Powell, Elizabeth (2017). Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia. Internal Medicine Journal, 47 (4), 429-435. doi: 10.1111/imj.13380

Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia

2017

Journal Article

IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis

Eslam, Mohammed, McLeod, Duncan, Kelaeng, Kebitsaone Simon, Mangia, Alessandra, Berg, Thomas, Thabet, Khaled, Irving, William L., Dore, Gregory J., Sheridan, David, Gronbaek, Henning, Abate, Maria Lorena, Hartmann, Rune, Bugianesi, Elisabetta, Spengler, Ulrich, Rojas, Angela, Booth, David R., Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Mahajan, Hema, Fischer, Janett, Nattermann, Jacob, Douglas, Mark W., Liddle, Christopher, Powell, Elizabeth, Romero-Gomez, Manuel and George, Jacob (2017). IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis. Nature Genetics, 49 (5), 795-800. doi: 10.1038/ng.3836

IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis

2017

Journal Article

Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study

Nicoletti, Paola, Aithal, Guruprasad P., Bjornsson, Einar S., Andrade, Raul J. A, Sawle, Ashley, Arrese, Marco, Barnhart, Huiman X., Bondon-Guitton, Emmanuelle, Hayashi, Paul H., Bessone, Fernando, Carvajal, Alfonso, Cascorbi, Ingolf, Cirulli, Elizabeth T., Chalasani, Naga, Conforti, Anita, Coulthard, Sally A., Daly, Mark J., Day, Christopher P., Dillon, John F., Fontana, Robert J., Grove, Jane I., Hallberg, Pär, Hernandez, Nelia, Ibanez, Luisa, Kullak-Ublick, Gerd A., Laitinen, Tarja, Larrey, Dominique, Lucena, M. Isabel, Maitland-van der Zee, Anke H. ... Daly, Ann K. (2017). Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study. Gastroenterology, 152 (5), 1078-1089. doi: 10.1053/j.gastro.2016.12.016

Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study

2017

Conference Publication

Enhanced Liver Fibrosis test and liver stiffness measurements identify high prevalence of advanced fibrosis in people with type 2 diabetes

Patel, P. J., Stuart, K. A., Horsfall, L. U., Hayward, K. L., Hossain, F., Williams, S., Johnson, T., Brown, N., Lampe, G., Buck, L., Saad, N., Clouston, A., Irvine, K. M., Russell, A., Valery, P. C. and Powell, E. E. (2017). Enhanced Liver Fibrosis test and liver stiffness measurements identify high prevalence of advanced fibrosis in people with type 2 diabetes. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD, Australia, 20-22 August 2017. Richmond, VIC Australia: Wiley-Blackwell.

Enhanced Liver Fibrosis test and liver stiffness measurements identify high prevalence of advanced fibrosis in people with type 2 diabetes

2017

Conference Publication

Can modest alcohol intake be dismissed as a co-factor in diabetic patients with non-alcoholic fatty liver disease?

Patel, P. J., Smith, D. D., Stuart, K. A., Horsfall, L. U., Hayward, K. L., Hossain, F., Williams, S., Johnson, T., Brown, N. N., Saad, N., Clouston, A. D., Irvine, K. M., Russell, A. W., Valery, P. C. and Powell, E. E. (2017). Can modest alcohol intake be dismissed as a co-factor in diabetic patients with non-alcoholic fatty liver disease?. International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Amsterdam, Netherlands, 19-23 April 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0168-8278(17)31602-1

Can modest alcohol intake be dismissed as a co-factor in diabetic patients with non-alcoholic fatty liver disease?

2016

Journal Article

Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers

Irvine, Katharine M., Wockner, Leesa F., Hoffmann, Isabel, Horsfall, Leigh U., Fagan, Kevin J., Bijin, Veonice, Lee, Bernett, Clouston, Andrew D., Lampe, Guy, Connolly, John E. and Powell, Elizabeth E. (2016). Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers. PLoS ONE, 11 (11) 167001, e0167001. doi: 10.1371/journal.pone.0167001

Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers

2016

Journal Article

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C

Thabet, Khaled, Asimakopoulos, Anastasia, Shojaei, Maryam, Romero-Gomez, Manuel, Mangia, Alessandra, Irving, William L., Berg, Thomas, Dore, Gregory J., Gronbaek, Henning, Sheridan, David, Abate, Maria Lorena, Bugianesi, Elisabetta, Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Fischer, Janett, Spengler, Ulrich, Nattermann, Jacob, Wahid, Ahmed, Rojas, Angela, White, Rose, Douglas, Mark W., McLeod, Duncan, Powell, Elizabeth, Liddle, Christopher, Van Der Poorten, David, George, Jacob, Eslam, Mohammed ... Santaro, Rosanna (2016). MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C. Nature Communications, 7 (1) 12757, 12757. doi: 10.1038/ncomms12757

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C