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2025

Journal Article

Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis

Gilholm, Patricia, Lister, Paula, Irwin, Adam, Harley, Amanda, Raman, Sainath, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis. Maternal and Child Health Journal, 29 (5), 1-10. doi: 10.1007/s10995-025-04038-1

Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis

2025

Journal Article

The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research

Gibbons, Kristen S., Beca, John, Delzoppo, Carmel, Erickson, Simon, Festa, Marino, Gelbart, Ben, Long, Debbie, Masterson, Kate, Millar, Johnny, Raman, Sainath, Schlapbach, Luregn J., Butt, Warwick and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2025). The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research. Pediatric Critical Care Medicine, 26 (1), e122-e130. doi: 10.1097/pcc.0000000000003653

The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 years of collaborative research

2025

Journal Article

Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit

Mozun, Rebeca, Chopard, Daphné, Zapf, Florian, Baumann, Philipp, Brotschi, Barbara, Adam, Anika, Jaeggi, Vera, Bangerter, Beat, Gibbons, Kristen S., Burren, Juerg and Schlapbach, Luregn J. (2025). Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit. BMJ Open, 15 (1) e087043, 1-9. doi: 10.1136/bmjopen-2024-087043

Comparison of carbon dioxide control during pressure controlled versus pressure-regulated volume controlled ventilation in children (CoCO2): protocol for a pilot digital randomised controlled trial in a quaternary paediatric intensive care unit

2024

Journal Article

Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol

Raman, Sainath, Gibbons, Kristen S., Jayashree, Muralidharan, Lalitha, AV, Bellomo, Rinaldo, Blythe, Robin, Buckley, David, Butt, Warwick, Cho, Hwa Jin, Cree, Michele, de Souza, Daniela C., Erickson, Simon, Festa, Marino, Ganu, Subodh, George, Shane, James, Ebor Jacob, Johnson, Kerry, Le Marsney, Renate, Lister, Paula, Pham, Trang M. T., Singh, Puneet, Venkatesh, Balasubramanian, Wall, Renee, Long, Debbie A., Schlapbach, Luregn J. and on behalf of the Resuscitation in Paediatric Septic Shock using Vitamin C and Hydrocortisone (RESPOND) Study Group and the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2024). Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol. Pediatric Critical Care Medicine, 26 (3), 1-12. doi: 10.1097/pcc.0000000000003674

Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): the RESPOND Randomized Controlled Trial Protocol

2024

Journal Article

Hospital-acquired complications in critically ill children and PICU length of stay, duration of respiratory support, and economics: propensity score matching in a single-center cohort, 2015-2020

Schults, Jessica A., Hall, Lisa, Charles, Karina R., Rickard, Claire M., Le Marsney, Renate, Ergetu, Endrias, Gregg, Alex, Byrnes, Joshua, Rahiman, Sarfaraz, Long, Debbie, Lake, Anna and Gibbons, Kristen (2024). Hospital-acquired complications in critically ill children and PICU length of stay, duration of respiratory support, and economics: propensity score matching in a single-center cohort, 2015-2020. Pediatric Critical Care Medicine, 26 (3), e304-e314. doi: 10.1097/PCC.0000000000003668

Hospital-acquired complications in critically ill children and PICU length of stay, duration of respiratory support, and economics: propensity score matching in a single-center cohort, 2015-2020

2024

Journal Article

Provision of continuous renal replacement therapy in children in intensive care in Australia and New Zealand

Killick, Caroline J., Oberender, Felix, Ganu, Subodh, Gibbons, Kristen, Agarwal, Sidharth, Chiletti, Roberto, Erickson, Simon, Jackson, Hamish, Numa, Andrew, Plumpton, Kevin, Wiseman, Greg, Nakazawa, Kiraka and Hunter, John (2024). Provision of continuous renal replacement therapy in children in intensive care in Australia and New Zealand. Critical Care and Resuscitation, 26 (4), 271-278. doi: 10.1016/j.ccrj.2024.08.007

Provision of continuous renal replacement therapy in children in intensive care in Australia and New Zealand

2024

Journal Article

Barriers and facilitators to implementing adaptive trial designs in paediatric critical care: an international mixed-methods study

Gilholm, Patricia, Wu, Ken, Le Marsney, Renate and Gibbons, Kristen (2024). Barriers and facilitators to implementing adaptive trial designs in paediatric critical care: an international mixed-methods study. Intensive Care Medicine - Paediatric and Neonatal, 2 (1) 31. doi: 10.1007/s44253-024-00054-1

Barriers and facilitators to implementing adaptive trial designs in paediatric critical care: an international mixed-methods study

2024

Journal Article

Urinary chloride excretion in critical illness and acute kidney injury: a paediatric hypothesis-generating cohort study post cardiopulmonary bypass surgery

Mattke, Adrian C., Johnson, Kerry E., Ariyawansa, Krishanti, Trnka, Peter, Venugopal, Prem S., Coman, David, Schibler, Andreas and Gibbons, Kristen (2024). Urinary chloride excretion in critical illness and acute kidney injury: a paediatric hypothesis-generating cohort study post cardiopulmonary bypass surgery. Anaesthesia and Intensive Care, 52 (6) 310057X241265119, 1-10. doi: 10.1177/0310057X241265119

Urinary chloride excretion in critical illness and acute kidney injury: a paediatric hypothesis-generating cohort study post cardiopulmonary bypass surgery

2024

Journal Article

The authors reply:

Raman, Sainath, Gibbons, Kristen, LeMarsney, Renate and Schlapbach, Luregn J. (2024). The authors reply:. Pediatric Critical Care Medicine, 25 (9), e398-e399. doi: 10.1097/pcc.0000000000003578

The authors reply:

2024

Journal Article

Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world

Sanchez-Pinto, L. Nelson, del Pilar Arias López, María, Scott, Halden, Gibbons, Kristen, Moor, Michael, Watson, R. Scott, Wiens, Matthew O., Schlapbach, Luregn J. and Bennett, Tellen D. (2024). Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world. The Lancet Digital Health, 6 (9), e651-e661. doi: 10.1016/s2589-7500(24)00141-9

Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world

2024

Journal Article

Neurodevelopmental outcome and quality of life in children admitted to the paediatric intensive care unit: A single-centre Australian cohort study

Long, Debbie, Minogue, Jessicah, Charles, Karina, Morgan, Suzanne, Schults, Jessica, Le Marsney, Renate, Stocker, Christian, Gibbons, Kristen S. and Dow, Belinda (2024). Neurodevelopmental outcome and quality of life in children admitted to the paediatric intensive care unit: A single-centre Australian cohort study. Australian Critical Care, 37 (6), 903-911. doi: 10.1016/j.aucc.2024.05.001

Neurodevelopmental outcome and quality of life in children admitted to the paediatric intensive care unit: A single-centre Australian cohort study

2024

Journal Article

Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study

Schlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8

Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study

2024

Journal Article

Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis

Khan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Phillips, Natalie (RSG member), Irwin, Adam (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768

Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis

2024

Journal Article

Fluid management and active fluid removal practices: a global survey of paediatric critical care physicians

Aramburo, Angela, Raman, Sainath, Silversides, Jonathan A., Schlapbach, Luregn J., Gibbons, Kristen S., Ramnarayan, Padmanabhan, on behalf of the Australian, New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), the United Kingdom Paediatric Critical Care Society Study Group (PCCS-SG), Pellegrini, Breanna, George, Shane, Balit, Corrine, Oberender, Felix, Erickson, Simon, Flores, Jenipher Chumbes, Charles, Karina, Waak, Michaela, Long, Debbie, Butt, Warwick, Delzoppo, Carmel, Gelbart, Ben, Masterson, Kate, Millar, Johnny, Ganeshalingam, Anusha, Sherring, Claire, Singh, Puneet, Smith, Vicky, Schults, Jessica, Darvas, Jennifer and Festa, Marino (2024). Fluid management and active fluid removal practices: a global survey of paediatric critical care physicians. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 16, 1-16. doi: 10.1007/s44253-024-00038-1

Fluid management and active fluid removal practices: a global survey of paediatric critical care physicians

2024

Journal Article

Defining woman-centred care: A concept analysis

Brady, Susannah, Gibbons, Kristen S. and Bogossian, Fiona (2024). Defining woman-centred care: A concept analysis. Midwifery, 131 103954, 1-9. doi: 10.1016/j.midw.2024.103954

Defining woman-centred care: A concept analysis

2024

Journal Article

Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudy

van Loon, Kim, Koomen, Erik, Hiensch, Senna, van Belle- van Haaren, Nicole J. C. W., Koelhuis-Faber, Mizja, Charlier, Jean-Luc, Lammers, Jan, Imhof, Oscar, Nijman, Joppe, van Wijk, Abraham, Breur, Johannes M. P. J., Gibbons, Kristen, Butt, Warwick, Schlapbach, Luregn J., Horton, Stephen, Korporaal, Suzanne and the NITRIC Study Group (2024). Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudy. Intensive Care Medicine – Paediatric and Neonatal, 2 (1) 13. doi: 10.1007/s44253-024-00037-2

Platelet reactivity in young children undergoing congenital heart disease surgery: a NITRIC randomized clinical trial substudy

2024

Journal Article

Establishing a paediatric critical care core quality measure set using a multistakeholder, consensus-driven process

Schults, Jessica A., Charles, Karina R., Millar, Johnny, Rickard, Claire M., Chopra, Vineet, Lake, Anna, Gibbons, Kristen, Long, Debbie, Rahiman, Sarfaraz, Hutching, Katrina, Winderlich, Jacinta, Spotswood, Naomi E., Johansen, Amy, Secombe, Paul, Pizimolas, Georgina A., Tu, Quyen, Waak, Michaela, Allen, Meredith, McMullan, Brendan and Hall, Lisa (2024). Establishing a paediatric critical care core quality measure set using a multistakeholder, consensus-driven process. Critical Care and Resuscitation, 26 (2), 71-79. doi: 10.1016/j.ccrj.2024.01.002

Establishing a paediatric critical care core quality measure set using a multistakeholder, consensus-driven process

2024

Journal Article

Assessing the impact of risk-based data monitoring on outcomes for a paediatric multicentre randomised controlled trial

Le Marsney, Renate, Johnson, Kerry, Chumbes Flores, Jenipher, Coetzer, Shelley, Darvas, Jennifer, Delzoppo, Carmel, Jolly, Arielle, Masterson, Kate, Sherring, Claire, Thomson, Hannah, Ergetu, Endrias, Gilholm, Patricia and Gibbons, Kristen S. (2024). Assessing the impact of risk-based data monitoring on outcomes for a paediatric multicentre randomised controlled trial. Clinical Trials, 21 (4), 461-469. doi: 10.1177/17407745231222019

Assessing the impact of risk-based data monitoring on outcomes for a paediatric multicentre randomised controlled trial

2024

Journal Article

Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study

McWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J., on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators, Irwin, Adam (RAPIDS member) and Bialasiewicz, Seweryn (RAPIDS member) (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349

Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study

2024

Journal Article

Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial

Harley, Amanda, George, Shane, Phillips, Natalie, King, Megan, Long, Debbie, Keijzers, Gerben, Lister, Paula, Raman, Sainath, Bellomo, Rinaldo, Gibbons, Kristen, Schlapbach, Luregn J. and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform Study in the Emergency Department (RESPOND ED) Study Group (2024). Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial. Pediatric Critical Care Medicine, 25 (2), 106-117. doi: 10.1097/PCC.0000000000003351

Resuscitation with early adrenaline infusion for children with septic shock: a randomized pilot trial