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2017 Journal Article Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cellsGao, Yulong, Souza-Fonseca-Guimaraes, Fernando, Bald, Tobias, Ng, Susanna S., Young, Arabella, Ngiow, Shin Foong, Rautela, Jai, Straube, Jasmin, Waddell, Nic, Blake, Stephen J., Yan, Juming, Bartholin, Laurent, Lee, Jason S., Vivier, Eric, Takeda, Kazuyoshi, Messaoudene, Meriem, Zitvogel-, Laurence, Teng, Michele W. L., Belz, Gabrielle T., Engwerda, Christian R., Huntington, Nicholas D., Nakamura, Kyohei, Hoelzel, Michael and Smyth, Mark J. (2017). Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells. Nature Immunology, 18 (9), 1004-1015. doi: 10.1038/ni.3800 |
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2017 Journal Article G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesisCasciello, Francesco, Al-Ejeh, Fares, Kelly, Greg, Brennan, Donal J., Ngiow, Shin Foong, Young, Arabella, Stoll, Thomas, Windloch, Karolina, Hill, Michelle M., Smyth, Mark J., Gannon, Frank and Lee, Jason S. (2017). G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis. Proceedings of the National Academy of Sciences, 114 (27), 7077-7082. doi: 10.1073/pnas.1618706114 |
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2017 Journal Article Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cellsZhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152 |
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2016 Journal Article Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 RegulationGhoussaini, Maya, French, Juliet D., Michailidou, Kyriaki, Nord, Silje, Beesley, Jonathan, Canisus, Sander, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lee, Jason S., Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Milne, Roger L., Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Muir, Kenneth, Lophatananon, Artitaya, Fasching, Peter A., Beckmann, Matthias W., Fletcher, Olivia, Johnson, Nichola, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara ... kConFab/AOCS Investigators (2016). Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. American Journal of Human Genetics, 99 (4), 903-911. doi: 10.1016/j.ajhg.2016.07.017 |
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2016 Journal Article Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunityKarunarathne, Deshapriya S., Horne-Debets, Joshua M., Huang, Johnny X., Faleiro, Rebecca, Leow, Chiuan Yee, Amante, Fiona, Watkins, Thomas S., Miles, John J., Dwyer, Patrick J., Stacey, Katryn J., Yarski, Michael, Poh, Chek Meng, Lee, Jason S., Cooper, Matthew A., Rénia, Laurent, Richard, Derek, McCarthy, James S., Sharpe, Arlene H. and Wykes, Michelle N. (2016). Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunity. Immunity, 45 (2), 333-345. doi: 10.1016/j.immuni.2016.07.017 |
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2016 Journal Article Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis VariantLi, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R. M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex ... Chenevix-Trench, Georgia (2016). Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. American Journal of Human Genetics, 98 (5), 830-842. doi: 10.1016/j.ajhg.2016.03.001 |
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2016 Journal Article Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170Dunning, Alison M., Michailidou, Kyriaki, Kuchenbaecker, Karoline B., Thompson, Deborah, French, Juliet D., Beesley, Jonathan, Healey, Catherine S., Kar, Siddhartha, Pooley, Karen A., Lopez-Knowles, Elena, Dicks, Ed, Barrowdale, Daniel, Sinnott-Armstrong, Nicholas A., Sallari, Richard C., Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Marjaneh, Mahdi Moradi, Lee, Jason S., Hills, Margaret, Jarosz, Monika, Drury, Suzie, Canisius, Sander, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Hopper, John L., Southey, Melissa C., Broeks, Annegien ... Edwards, Stacey L. (2016). Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics, 48 (4), 374-386. doi: 10.1038/ng.3521 |
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2016 Journal Article The anticancer effect of chaetocin is enhanced by inhibition of autophagyJung, H-J, Seo, I, Casciello, F, Jacquelin, S, Lane, S W, Suh, S-Il, Suh, M-H, Lee, J S and Baek, W-K (2016). The anticancer effect of chaetocin is enhanced by inhibition of autophagy. Cell death & disease, 7 (2) e2098, e2098-e2098. doi: 10.1038/cddis.2016.15 |
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2016 Journal Article Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancerFrench, Juliet D., Johnatty, Sharon E., Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J., Russell, Amanda J., Kar, Siddhartha, Chen, Xiaoging, Hillman, Kristine M., Kaufmann, S, Sivakumaran H., O'Reilly, Martin, Wang, Chen, Korbie, Darren J., Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandra, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander ... MacGregor, Stuart (2016). Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. Oncotarget, 7 (6), 6353-6368. doi: 10.18632/oncotarget.7047 |
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2015 Journal Article Functional role of G9a histone methyltransferase in cancerCasciello, Francesco, Windloch, Karolina, Gannon, Frank and Lee, Jason S. (2015). Functional role of G9a histone methyltransferase in cancer. Frontiers in Immunology, 6 (SEP) 487, 487.1-487.12. doi: 10.3389/fimmu.2015.00487 |
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2015 Journal Article Long-range modulation of PAG1 expression by 8q21 allergy risk variantsVicente, Cristina T., Edwards, Stacey L., Hillman, Kristine M., Kaufmann, Susanne, Mitchell, Hayley, Bain, Lisa, Glubb, Dylan M., Lee, Jason S., French, Juliet D. and Ferreira, Manuel A. R. (2015). Long-range modulation of PAG1 expression by 8q21 allergy risk variants. American Journal of Human Genetics, 97 (2) 1909, 329-336. doi: 10.1016/j.ajhg.2015.06.010 |
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2015 Journal Article DNAM-1 expression marks an alternative program of NK cell maturationMartinet, Ludovic, FerrariDeAndrade, Lucas, Guillerey, Camille, Lee, Jason S, Liu, Jing, Souza-Fonseca-Guimaraes, Fernando, Hutchinson, Dana S, Kolesnik, Tatiana B, Nicholson, Sandra E, Huntington, Nicholas D and Smyth, Mark J (2015). DNAM-1 expression marks an alternative program of NK cell maturation. Cell Reports, 11 (1), 85-97. doi: 10.1016/j.celrep.2015.03.006 |
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2014 Journal Article Epigenetic regulation in cancer progressionBaxter, Eva, Windloch, Karolina, Gannon, Frank and Lee, Jason S. (2014). Epigenetic regulation in cancer progression. Cell & Bioscience, 4 (1) 45, 45. doi: 10.1186/2045-3701-4-45 |
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2012 Journal Article EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complexLee, Ji Min, Lee, Jason S., Kim, Hyunkyung, Kim, Kyeong Kyu, Park, Hyejin, Kim, Ji-Young, Lee, Seung Hoon, Kim, Ik Soo, Kim, Joomyung, Lee, Minkyoung, Chung, Chin Ha, Seo, Sang-Beom, Yoon, Jong-Bok, Ko, Eunyoung, Noh, Dong-Young, Kim, Keun Il and Baek, Sung Hee (2012). EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex. Molecular Cell, 48 (4), 572-586. doi: 10.1016/j.molcel.2012.09.004 |
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2011 Journal Article DNA damage-induced RORα Is crucial for p53 stabilization and increased apoptosisKim, Hyunkyung, Lee, Ji Min, Lee, Gina, Bhin, Jinhyuk, Oh, Se Kyu, Kim, Kyeongkyu, Pyo, Ki Eun, Lee, Jason S., Yim, Hwa Young, Kim, Keun Il, Hwang, Daehee, Chung, Jongkyeong and Baek, Sung Hee (2011). DNA damage-induced RORα Is crucial for p53 stabilization and increased apoptosis. Molecular Cell, 44 (5), 797-810. doi: 10.1016/j.molcel.2011.09.023 |
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2011 Journal Article Hypoxia-induced methylation of a pontin chromatin remodeling factorLee, Jason S., Kim, Yunho, Bhin, Jinhyuk, Shin, Hi-Jai R., Nam, Hye Jin, Lee, Seung Hoon, Yoon, Jong-Bok, Binda, Olivier, Gozani, Or, Hwang, Daehee and Baek, Sung Hee (2011). Hypoxia-induced methylation of a pontin chromatin remodeling factor. Proceedings of the National Academy of Sciences of the United States of America, 108 (33), 13510-13515. doi: 10.1073/pnas.1106106108 |
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2010 Journal Article Induction of cellular apoptosis in human breast cancer by DLBS1425, a Phaleria macrocarpa compound extract, via downregulation of PI3-kinase/AKT pathwayTandrasasmita, Olivia M., Lee, Jason S., Baek, Sung Hee and Tjandrawinata, Raymond R. (2010). Induction of cellular apoptosis in human breast cancer by DLBS1425, a Phaleria macrocarpa compound extract, via downregulation of PI3-kinase/AKT pathway. Cancer Biology and Therapy, 10 (8), 814-823. doi: 10.4161/cbt.10.8.13085 |
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2010 Journal Article Negative regulation of hypoxic responses via induced reptin methylationLee, Jason S., Kim, Yunho, Kim, Ik Soo, Kim, Bogyou, Choi, Hee June, Lee, Ji Min, Shin, Hi-Jai R., Kim, Jung Hwa, Kim, Ji-Young, Seo, Sang-Beom, Lee, Ho, Binda, Olivier, Gozani, Or, Semenza, Gregg L., Kim, Minhyung, Kim, Keun Il, Hwang, Daehee and Baek, Sung Hee (2010). Negative regulation of hypoxic responses via induced reptin methylation. Molecular Cell, 39 (1), 71-85. doi: 10.1016/j.molcel.2010.06.008 |
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2010 Journal Article Identification of the KAI1 metastasis suppressor gene as a hypoxia target geneKim, Bogyou, Boo, Kyungjin, Lee, Jason S., Kim, Keun Il, Kim, Woo Ho, Cho, Hyun-Jai, Park, Young-Bae, Kim, Hyo-Soo and Baek, Sung Hee (2010). Identification of the KAI1 metastasis suppressor gene as a hypoxia target gene. Biochemical and Biophysical Research Communications, 393 (1), 179-184. doi: 10.1016/j.bbrc.2010.01.118 |
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2010 Journal Article RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon CancerLee, Ji Min, Kim, Ik Soo, Kim, Hyunkyung, Lee, Jason S., Kim, Kyeongkyu, Yim, Hwa Young, Jeong, Jiyeong, Kim, Jung Hwa, Kim, Ji-Young, Lee, Hanna, Seo, Sang-Beom, Kim, Hogeun, Rosenfeld, Michael G., Kim, Keun Il and Baek, Sung Hee (2010). RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon Cancer. Molecular Cell, 37 (2), 183-195. doi: 10.1016/j.molcel.2009.12.022 |
