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2019

Journal Article

Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation

Fanning, Jonathon P., Hoe, Louise E. See, Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky Y. and Fraser, John F. (2019). Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation. The American Journal of Cardiology, 123 (3), 434-439. doi: 10.1016/j.amjcard.2018.10.022

Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation

2019

Journal Article

Sepsis: changing definitions, unchanging treatment

Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2019). Sepsis: changing definitions, unchanging treatment. Frontiers in Pediatrics, 6 (JAN) 425, 425. doi: 10.3389/fped.2018.00425

Sepsis: changing definitions, unchanging treatment

2019

Journal Article

Sedatives, analgesics, and antipsychotics in tracheostomised intensive care unit patients – Is less more?

Sutt, Anna-Liisa, Hay, Karen, Kinneally, Toni, Fisquet, Stephanie and Fraser, John F. (2019). Sedatives, analgesics, and antipsychotics in tracheostomised intensive care unit patients – Is less more?. Australian Critical Care, 33 (5), 407-411. doi: 10.1016/j.aucc.2018.12.004

Sedatives, analgesics, and antipsychotics in tracheostomised intensive care unit patients – Is less more?

2019

Conference Publication

In vitro testing of cyanoacrylate tissue adhesives and sutures for extracorporeal membrane oxygenation cannula securement

Lye, India, Corley, Amanda, Bartnikowski, Nicole and Fraser, John (2019). In vitro testing of cyanoacrylate tissue adhesives and sutures for extracorporeal membrane oxygenation cannula securement. 43rd Australian and New Zealand Annual Scientific Meeting on Intensive Care and the 24th Annual Paediatric and Neonatal Intensive Care Conference, Adelaide, SA Australia, 11-13 October 2018. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2018.11.038

In vitro testing of cyanoacrylate tissue adhesives and sutures for extracorporeal membrane oxygenation cannula securement

2019

Conference Publication

Improving In vitro evaluation capabilities of cardiac assist devices through a validated exercise simulation

Pauls, Jo P., Roberts, Llion A., Stephens, Andrew, Fraser, John F., Tansley, Geoff and Gregory, Shaun D. (2019). Improving In vitro evaluation capabilities of cardiac assist devices through a validated exercise simulation. Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Berlin, Germany, 23-27 July 2019. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/embc.2019.8856936

Improving In vitro evaluation capabilities of cardiac assist devices through a validated exercise simulation

2019

Journal Article

Improving skin integration around long-term percutaneous devices using fibrous scaffolds in a reconstructed human skin equivalent model

Bolle, Eleonore C. L., Bartnikowski, Nicole, Haridas, Parvathi, Parker, Tony J., Fraser, John F., Gregory, Shaun D. and Dargaville, Tim R. (2019). Improving skin integration around long-term percutaneous devices using fibrous scaffolds in a reconstructed human skin equivalent model. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 108 (3) jbm.b.34428, 738-749. doi: 10.1002/jbm.b.34428

Improving skin integration around long-term percutaneous devices using fibrous scaffolds in a reconstructed human skin equivalent model

2019

Conference Publication

Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model

Hoe, L. See, Shuker, T., Bartnikowski, N., Passmore, M., Bouquet, M., Obonyo, N., Engkilde-Pedersen, S., McDonald, C., Wells, M., Boon, A., Hyslop, K., James, L., Wildi, K., Cullen, L., Bassi, G. Li, Suen, J., McGiffin, D. and Fraser, J. (2019). Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model. 67th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 13th Annual Australia and New Zealand Endovascular Therapies Meeting, Adelaide, Australia, 8-11 August 2019. chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2019.06.074

Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model

2019

Journal Article

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

2018

Journal Article

Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial

Macdonald, Stephen P. J., Keijzers, Gerben, Taylor, David McD, Kinnear, Frances, Arendts, Glenn, Fatovich, Daniel M., Bellomo, Rinaldo, McCutcheon, David, Fraser, John F., Ascencio-Lane, Juan-Carlos, Burrows, Sally, Litton, Edward, Harley, Amanda, Anstey, Matthew and Mukherjee, Ashes (2018). Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial. Intensive Care Medicine, 44 (12), 2070-2078. doi: 10.1007/s00134-018-5433-0

Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial

2018

Journal Article

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

2018

Journal Article

Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia

Li Bassi, G., Comaru, T., Martí, D., Xiol, E. A., Chiurazzi, C., Travierso, C., Carbonara, M., Ranzani, O. T., Amaro, R., Frigola, G., Fuster, C., Saco, M. A., Zanella, A., De Rosa, F., Rigol, M., Fernandez, L., Luque, N., Ramirez, J., Blasi, F., Suen, J., Fraser, J. and Torres, A. (2018). Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia. British Journal of Anaesthesia, 122 (2), 269-276. doi: 10.1016/j.bja.2018.07.039

Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia

2018

Journal Article

The effects of normovolemic anemia and blood transfusion on cerebral microcirculation after severe head injury

Bellapart, Judith, Cuthbertson, Kylie, Dunster, Kimble, Diab, Sara, Platts, David G., Raffel, Christopher, Gabrielian, Levon, Barnett, Adrian, Paratz, Jennifer, Boots, Rob and Fraser, John F. (2018). The effects of normovolemic anemia and blood transfusion on cerebral microcirculation after severe head injury. Intensive Care Medicine Experimental, 6 (1) 46, 46. doi: 10.1186/s40635-018-0210-5

The effects of normovolemic anemia and blood transfusion on cerebral microcirculation after severe head injury

2018

Conference Publication

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation. American Heart Association's 2018 Scientific Sessions, Chicago, IL United States, 10-12 November 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/circ.138.suppl_1.17116

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

2018

Journal Article

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

2018

Journal Article

An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activity

Sreevatsav Adiraju, Santosh Kumar, Shekar, Kiran, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2018). An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activity. Bioanalysis, 10 (19), 1577-1590. doi: 10.4155/bio-2018-0102

An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activity

2018

Journal Article

Corrigendum to “Ventilation distribution and lung recruitment with speaking valve use in tracheostomised patient weaning from mechanical ventilation in intensive care” [Journal of Critical Care 40 (2017) 164–170]

Sutt, Anna-Liisa, Anstey, Chris M., Caruana, Lawrence R., Cornwell, Petrea L. and Fraser, John F. (2018). Corrigendum to “Ventilation distribution and lung recruitment with speaking valve use in tracheostomised patient weaning from mechanical ventilation in intensive care” [Journal of Critical Care 40 (2017) 164–170]. Journal of Critical Care, 48, 481-481. doi: 10.1016/j.jcrc.2018.09.007

Corrigendum to “Ventilation distribution and lung recruitment with speaking valve use in tracheostomised patient weaning from mechanical ventilation in intensive care” [Journal of Critical Care 40 (2017) 164–170]

2018

Journal Article

Are pressure injuries related to skin failure in critically ill patients?

Nowicki, Jake L., Mullany, Daniel, Spooner, Amy, Nowicki, Tracy A., Mckay, Peta M., Corley, Amanda, Fulbrook, Paul and Fraser, John F. (2018). Are pressure injuries related to skin failure in critically ill patients?. Australian Critical Care, 31 (5), 257-263. doi: 10.1016/j.aucc.2017.07.004

Are pressure injuries related to skin failure in critically ill patients?

2018

Journal Article

Dressings and securements for the prevention of peripheral intravenous catheter failure in adults (SAVE): a pragmatic, randomised controlled, superiority trial

Rickard, Claire M., Marsh, Nicole, Webster, Joan, Runnegar, Naomi, Larsen, Emily, McGrail, Matthew R., Fullerton, Fiona, Bettington, Emilie, Whitty, Jennifer A., Abu Choudhury, Md, Tuffaha, Haitham, Corley, Amanda, McMillan, David J., Fraser, John F., Marshall, Andrea P. and Playford, E. Geoffrey (2018). Dressings and securements for the prevention of peripheral intravenous catheter failure in adults (SAVE): a pragmatic, randomised controlled, superiority trial. Lancet, 392 (10145), 419-430. doi: 10.1016/S0140-6736(18)31380-1

Dressings and securements for the prevention of peripheral intravenous catheter failure in adults (SAVE): a pragmatic, randomised controlled, superiority trial

2018

Journal Article

High flow nasal oxygen after bariatric surgery (OXYBAR), prophylactic post-operative high flow nasal oxygen versus conventional oxygen therapy in obese patients undergoing bariatric surgery: study protocol for a randomised controlled pilot trial

Fulton, Rachel, Millar, Jonathan E., Merza, Megan, Johnston, Helen, Corley, Amanda, Faulke, Daniel, Rapchuk, Ivan, Tarpey, Joe, Lockie, Philip, Lockie, Shirley and Fraser, John F. (2018). High flow nasal oxygen after bariatric surgery (OXYBAR), prophylactic post-operative high flow nasal oxygen versus conventional oxygen therapy in obese patients undergoing bariatric surgery: study protocol for a randomised controlled pilot trial. Trials, 19 (1) 402, 402. doi: 10.1186/s13063-018-2777-2

High flow nasal oxygen after bariatric surgery (OXYBAR), prophylactic post-operative high flow nasal oxygen versus conventional oxygen therapy in obese patients undergoing bariatric surgery: study protocol for a randomised controlled pilot trial

2018

Journal Article

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models