2022 Journal Article Cyclic ADP ribose isomers: Production, chemical structures, and immune signalingManik, Mohammad K., Shi, Yun, Li, Sulin, Zaydman, Mark A., Damaraju, Neha, Eastman, Samuel, Smith, Thomas G., Gu, Weixi, Masic, Veronika, Mosaiab, Tamim, Weagley, James S., Hancock, Steven J., Vasquez, Eduardo, Hartley-Tassell, Lauren, Kargios, Nestoras, Maruta, Natsumi, Lim, Bryan Y. J., Burdett, Hayden, Landsberg, Michael J., Schembri, Mark A., Prokes, Ivan, Song, Lijiang, Grant, Murray, DiAntonio, Aaron, Nanson, Jeffrey D., Guo, Ming, Milbrandt, Jeffrey, Ve, Thomas and Kobe, Bostjan (2022). Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science, 377 (6614) eadc8969, 1-11. doi: 10.1126/science.adc8969 |
2021 Journal Article A broadly protective antibody that targets the flavivirus NS1 proteinModhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425 |
2020 Journal Article Structures of fungal and plant acetohydroxyacid synthasesLonhienne, Thierry, Low, Yu Shang, Garcia, Mario D., Croll, Tristan, Gao, Yan, Wang, Quan, Brillault, Lou, Williams, Craig M., Fraser, James A., McGeary, Ross P., West, Nicholas P., Landsberg, Michael J., Rao, Zihe, Schenk, Gerhard and Guddat, Luke W. (2020). Structures of fungal and plant acetohydroxyacid synthases. Nature, 586 (7828), 317-321+. doi: 10.1038/s41586-020-2514-3 |
2019 Journal Article Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxinPiper, Sarah J., Brillault, Lou, Rothnagel, Rosalba, Croll, Tristan I., Box, Joseph K., Chassagnon, Irene, Scherer, Sebastian, Goldie, Kenneth N, Jones, Sandra A, Schepers, Femke, Hartley-Tassell, Lauren, Ve, Thomas, Busby, Jason N, Dalziel, Julie E, Lott, J Shaun, Hankamer, Ben, Stahlberg, Henning, Hurst, Mark R H and Landsberg, Michael J (2019). Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin. Nature Communications, 10 (1) 1952, 1952. doi: 10.1038/s41467-019-09890-8 |
2013 Journal Article The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation deviceBusby, Jason N., Panjikar, Santosh, Landsberg, Michael J., Hurst, Mark R. H. and Lott, J. Shaun (2013). The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device. Nature, 501 (7468), 547-550. doi: 10.1038/nature12465 |
2011 Journal Article 3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activityLandsberg, Michael J., Jones, Sandra A., Rothnagel, Rosalba, Busby, Jason N., Marshall, Sean D. G., Simpson, Robert M., Lott, J. Shaun, Hankamer, Ben and Hurst, Mark R. H. (2011). 3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activity. Proceedings of the National Academy of Sciences of the United States of America, 108 (51), 20544-20549. doi: 10.1073/pnas.1111155108 |
2024 Journal Article Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysisHuang, Stephen, Reed, Casie, Ilsley, Melissa, Magor, Graham, Tallack, Michael, Landsberg, Michael, Mitchell, Helen, Gillinder, Kevin and Perkins, Andrew (2024). Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis. Nature Communications, 15 (1) 7019, 1-16. doi: 10.1038/s41467-024-50579-4 |
2024 Journal Article The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both shell and cargoBusby, Jason N., Trevelyan, Sarah, Pegg, Cassandra L., Kerr, Edward D., Schulz, Benjamin L., Chassagnon, Irene, Landsberg, Michael J., Weston, Mitchell K., Hurst, Mark R. H. and Lott, J. Shaun (2024). The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both shell and cargo. IUCrJ, 11 (3), 299-308. doi: 10.1107/s2052252524001969 |
2023 Conference Publication TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathwaysNanson, J. D., Muusse, T. W., Li, Y., Pan, M., Landsberg, M. J., Vajjhala, P. R., Ve, T., Stacey, K. J. and Kobe, B. (2023). TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathways. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086631 |
2023 Conference Publication Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancersKwah, Kayden, Gu, Weixi, Arachchige, Kasun S. A., He, Yaowu, Landsberg, Michael, Kobe, Bostjan and Hooper, John (2023). Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323084449 |
2023 Conference Publication Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1Shi, Y., Nanson, J., Gu, W., Masic, V., Mosaiab, T., Landsberg, M., Kobe, B. and Ve, T. (2023). Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087776 |
2023 Journal Article Structure and antigenicity of divergent Henipavirus fusion glycoproteinsIsaacs, Ariel, Low, Yu Shang, Macauslane, Kyle L., Seitanidou, Joy, Pegg, Cassandra L., Cheung, Stacey T. M., Liang, Benjamin, Scott, Connor A. P., Landsberg, Michael J., Schulz, Benjamin L., Chappell, Keith J., Modhiran, Naphak and Watterson, Daniel (2023). Structure and antigenicity of divergent Henipavirus fusion glycoproteins. Nature Communications, 14 (1) 3577, 1-10. doi: 10.1038/s41467-023-39278-8 |
2023 Journal Article Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxinsAleksandrova, Nadezhda A., Roche, Solace G., Low, Yu Shang and Landsberg, Michael J. (2023). Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins. Biochemical Society Transactions, 51 (3), 1235-1244. doi: 10.1042/bst20221409 |
2023 Conference Publication Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determinationArvindekar, Shreyas M., Jackman, Matthew J., Low, Jason K. K., Landsberg, Michael J., Mackay, Joel P. and Viswanath, Shruthi (2023). Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination. Biophysical Society 67th Annual Meeting, San Diego, CA, United States, 18-22 February 2023. St. Louis, MO, United States: Cell Press. |
2023 Conference Publication Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determinationArvindekar, Shreyas M., Jackman, Matthew J., Low, Jason K.K., Landsberg, Michael J., Mackay, Joel P. and Viswanath, Shruthi (2023). Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination. 67th Biophysical Society Annual Meeting 2023, San Diego, CA United States, 18-22 February 2023. St Louis, MO United States: Cell Press. doi: 10.1016/j.bpj.2022.11.2531 |
2022 Journal Article Molecular architecture of nucleosome remodeling and deacetylase sub‐complexes by integrative structure determinationArvindekar, Shreyas, Jackman, Matthew J., Low, Jason K. K., Landsberg, Michael J., Mackay, Joel P. and Viswanath, Shruthi (2022). Molecular architecture of nucleosome remodeling and deacetylase sub‐complexes by integrative structure determination. Protein Science, 31 (9) e4387, 1-19. doi: 10.1002/pro.4387 |
2022 Conference Publication Structural basis of TIR-domain assembly formation in TRAM- and TRIF- dependent TLR signallingPan, M., Hedger, A., Nanson, J., Pospich, S., Ve, T. V. E. A., Raunser, S., Landsberg, M. and Kobe, B. (2022). Structural basis of TIR-domain assembly formation in TRAM- and TRIF- dependent TLR signalling. 2022 American Crystallographic Association Meeting, Portland, OR USA, 29 July-3 August 2022. Hoboken, NJ USA: Wiley-Blackwell Publishing. doi: 10.1107/s2053273322093196 |
2022 Journal Article Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform ChemicalsLv, You, Zheng, Shan, Goldenzweig, Adi, Liu, Fengjiang, Gao, Yan, Yang, Xiuna, Kandale, Ajit, McGeary, Ross P., Williams, Simon, Kobe, Bostjan, Schembri, Mark A., Landsberg, Michael J., Wu, Bin, Brück, Thomas B., Sieber, Volker, Boden, Mikael, Rao, Zihe, Fleishman, Sarel J., Schenk, Gerhard and Guddat, Luke W. (2022). Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals. Applied Biosciences, 1 (2), 163-178. doi: 10.3390/applbiosci1020011 |
2022 Journal Article Structural basis of SARM1 activation, substrate recognition, and inhibition by small moleculesShi, Yun, Kerry, Philip S., Nanson, Jeffrey D., Bosanac, Todd, Sasaki, Yo, Krauss, Raul, Saikot, Forhad K., Adams, Sarah E., Mosaiab, Tamim, Masic, Veronika, Mao, Xianrong, Rose, Faith, Vasquez, Eduardo, Furrer, Marieke, Cunnea, Katie, Brearley, Andrew, Gu, Weixi, Luo, Zhenyao, Brillault, Lou, Landsberg, Michael J., DiAntonio, Aaron, Kobe, Bostjan, Milbrandt, Jeffrey, Hughes, Robert O. and Ve, Thomas (2022). Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules. Molecular Cell, 82 (9), 1643-1659.e10. doi: 10.1016/j.molcel.2022.03.007 |
2022 Journal Article Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concernMcMillan, Christopher L. D., Azuar, Armira, Choo, Jovin J. Y., Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Honeyman, Kate E., Cheung, Stacey T. M., Liang, Benjamin, Wurm, Maria J., Pino, Paco, Kint, Joeri, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Hobson-Peters, Jody, Watterson, Daniel, Young, Paul R. and Muller, David A. (2022). Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern. Vaccines, 10 (4) 578, 578. doi: 10.3390/vaccines10040578 |