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2006 Journal Article Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibitionParekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029 |
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2006 Journal Article Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil AWhite, Karen, Rades, Thomas, Kearns, Philip, Toth, Istvan and Hook, Sarah (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23 (7), 1473-1481. doi: 10.1007/s11095-006-0272-z |
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2006 Journal Article Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparinHayes, Patricia Y., Ross, Benjamin P., Thomas, Bradley G. and Toth, Istvan (2006). Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin. Bioorganic & Medicinal Chemistry, 14 (1), 143-152. doi: 10.1016/j.bmc.2005.08.004 |
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2006 Journal Article Specific modulation of airway epithelial tight junctions by apical application of an occludin peptideEverett, Ruth S., Vanhook, Miriam K., Barozzi, Nadia, Toth, Istvan and Johnson, Larry G. (2006). Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide. Molecular Pharmacology, 69 (2), 492-500. doi: 10.1124/mol.105.017251 |
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2006 Journal Article Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane modelsPignatello, Rosario, Guccione, Salvatore, Castelli, Francesco, Sarpietro, Maria G., Giurato, Laura, Lombardo, Massimo, Puglisi, Giovanni and Toth, Istvan (2006). Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models. International Journal of Pharmaceutics, 310 (1-2), 53-63. doi: 10.1016/j.ijpharm.2005.11.044 |
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2006 Journal Article Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cellsWimmer, N., Robinson, J. A., Gopisetty Venkata, N., Roberts-Thomson, S. J., Monteith, G. R. and Toth, I. (2006). Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cells. Medicinal Chemistry, 2 (1), 79-87. doi: 10.2174/157340606775197714 |
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2006 Journal Article Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer systemWu, S., Christopher, C., Koda, Y., Blanchfield, J. T. and Toth, I. (2006). Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer system. Medicinal Chemistry, 2 (2), 203-211. doi: 10.2174/157340606776056205 |
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2005 Journal Article Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicityMarano, R. J., Toth, I., Wimmer, N., Brankov, M. and Rakoczy, E. P. (2005). Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Therapy, 12 (21), 1544-1550. doi: 10.1038/sj.gt.3302579 |
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2005 Journal Article Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancersRoss, B. P. and Toth, I. (2005). Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers. Current Drug Delivery, 2 (3), 277-287. doi: 10.2174/1567201054367968 |
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2005 Journal Article Functional implications of modifying RyR‐activating peptides for membrane permeabilityDulhunty, Angela F., Cengia, Louise, Young, Jacqui, Pace, Suzy M., Harvey, Peta J., Lamb, Graham D., Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan and Casarotto, Marco G. (2005). Functional implications of modifying RyR‐activating peptides for membrane permeability. British Journal of Pharmacology, 144 (6), 743-754. doi: 10.1038/sj.bjp.0705981 |
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2005 Journal Article Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-deliveryJohnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977 |
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2005 Journal Article Versatile peptide dendrimers for nucleic acid deliveryBayele, Henry, Sakthivel, T., O'Donell, Martin, Pasi, K. John, Wilderspin, Andrew F., Lee, Christine A., Toth, Istvan and Florence, Alexander T. (2005). Versatile peptide dendrimers for nucleic acid delivery. Journal of Pharmaceutical Sciences, 94 (2), 446-457. doi: 10.1002/jps.20230 |
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2005 Journal Article Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparationLiang, M. T., Davies, N. M. and Toth, I. (2005). Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation. International Journal of Pharmaceutics, 301 (1-2), 247-254. doi: 10.1016/j.ijpharm.2005.06.010 |
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2005 Journal Article The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptideBlanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069 |
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2004 Journal Article Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotideMarano, Robert J., Wimmer, Norbert, Kearns, Philip S., Thomas, Bradley G., Toth, Istvan, Brankov, Meliha and Rakoczy, P. Elizabeth (2004). Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Experimental Eye Research, 79 (4), 525-535. doi: 10.1016/j.exer.2004.06.023 |
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2004 Journal Article Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptidesWhite, K., Kearns, P., Toth, I. and Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology And Cell Biology, 82 (5), 517-522. doi: 10.1111/j.1440-1711.2004.01269.x |
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2004 Journal Article Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug deliveryRoss, Benjamin P., Braddy, April C., McGeary, Ross P., Blanchfield, Joanne T., Prokai, Laszlo and Toth, Istvan (2004). Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery. Molecular Pharmaceutics, 1 (3), 233-245. doi: 10.1021/mp049964d |
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2004 Journal Article Nucleophilic substitution reactions of pyranose polytosylatesMcGeary, R. P., Rasoul Amini, S., Tang, V. W. S. and Toth, I. (2004). Nucleophilic substitution reactions of pyranose polytosylates. Journal of Organic Chemistry, 69 (8), 2727-2730. doi: 10.1021/jo035779k |
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2004 Journal Article Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer modelMatthias, A., Blanchfield, J. T., Penman, K. G., Toth, I., Lang, C. S., De Voss, J. J. and Lehmann, R. P. (2004). Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy And Therapeutics, 29 (1), 7-13. doi: 10.1046/j.1365-2710.2003.00530.x |
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2004 Journal Article Design, Synthesis, and Evaluation of a Liposaccharide Drug Delivery Agent: Application to the Gastrointestinal Absorption of GentamicinRoss, B. P., DeCruz, S. E., Lynch, T. B., Davis-Goff, K. and Toth, I. (2004). Design, Synthesis, and Evaluation of a Liposaccharide Drug Delivery Agent: Application to the Gastrointestinal Absorption of Gentamicin. Journal of Medicinal Chemistry, 47 (5), 1251-1258. doi: 10.1021/jm030474j |
