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2006 Journal Article Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cellsWimmer, N., Robinson, J. A., Gopisetty Venkata, N., Roberts-Thomson, S. J., Monteith, G. R. and Toth, I. (2006). Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cells. Medicinal Chemistry, 2 (1), 79-87. doi: 10.2174/157340606775197714 |
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2006 Journal Article Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer systemWu, S., Christopher, C., Koda, Y., Blanchfield, J. T. and Toth, I. (2006). Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer system. Medicinal Chemistry, 2 (2), 203-211. doi: 10.2174/157340606776056205 |
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2006 Journal Article Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluationMoyle, P. M., Olive, C., Ho, M. F., Good, M. F. and Toth, I. (2006). Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation. Journal of Medicinal Chemistry, 49 (21), 6364-6370. doi: 10.1021/jm060475m |
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2006 Journal Article Protein transduction by lipidic peptide dendrimersBayele, Henry K., Ramaswamy, Chandrasekaran, Wilderspin, Andrew F., Srai, Kaila S., Toth, Istvan and Florence, Alexander T. (2006). Protein transduction by lipidic peptide dendrimers. Journal of Pharmaceutical Sciences, 95 (6), 1227-1237. doi: 10.1002/jps.20606 |
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2006 Journal Article Method for the synthesis of highly pure vaccines using the lipid core peptide systemMoyle, P. M., Olive, C., Good, M. F. and Toth, I. (2006). Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science, 12 (12), 800-807. doi: 10.1002/psc.815 |
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2006 Journal Article Dde as a protecting group for carbohydrate synthesisBornaghi, L., Dekany, G., Drinnan, N. B., Taylor, S., Toth, I. and West, M. L. (2006). Dde as a protecting group for carbohydrate synthesis. Journal of Carbohydrate Chemistry, 25 (1), 1-18. doi: 10.1080/07328300500388685 |
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2006 Journal Article Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptideCaccetta, R., Blanchfield, J. T., Harrison, J., Toth, I. and Benson, H. A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide. International Journal of Peptide Research and Therapeutics, 12 (3), 327-333. doi: 10.1007/s10989-006-9024-5 |
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2006 Journal Article Particulate systems as adjuvants and carriers for peptide and protein antigensLiang, M T, Davies, N M, Blanchfield, J T and Toth, I (2006). Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery, 3 (4), 379-388. doi: 10.2174/156720106778559029 |
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2005 Journal Article Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicityMarano, R. J., Toth, I., Wimmer, N., Brankov, M. and Rakoczy, E. P. (2005). Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Therapy, 12 (21), 1544-1550. doi: 10.1038/sj.gt.3302579 |
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2005 Journal Article Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancersRoss, B. P. and Toth, I. (2005). Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers. Current Drug Delivery, 2 (3), 277-287. doi: 10.2174/1567201054367968 |
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2005 Journal Article Functional implications of modifying RyR‐activating peptides for membrane permeabilityDulhunty, Angela F., Cengia, Louise, Young, Jacqui, Pace, Suzy M., Harvey, Peta J., Lamb, Graham D., Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan and Casarotto, Marco G. (2005). Functional implications of modifying RyR‐activating peptides for membrane permeability. British Journal of Pharmacology, 144 (6), 743-754. doi: 10.1038/sj.bjp.0705981 |
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2005 Journal Article The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptideBlanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069 |
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2005 Journal Article Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-deliveryJohnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977 |
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2005 Journal Article Versatile peptide dendrimers for nucleic acid deliveryBayele, Henry, Sakthivel, T., O'Donell, Martin, Pasi, K. John, Wilderspin, Andrew F., Lee, Christine A., Toth, Istvan and Florence, Alexander T. (2005). Versatile peptide dendrimers for nucleic acid delivery. Journal of Pharmaceutical Sciences, 94 (2), 446-457. doi: 10.1002/jps.20230 |
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2005 Journal Article Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparationLiang, M. T., Davies, N. M. and Toth, I. (2005). Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation. International Journal of Pharmaceutics, 301 (1-2), 247-254. doi: 10.1016/j.ijpharm.2005.06.010 |
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2004 Journal Article Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptidesWhite, K., Kearns, P., Toth, I. and Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology And Cell Biology, 82 (5), 517-522. doi: 10.1111/j.1440-1711.2004.01269.x |
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2004 Journal Article Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotideMarano, Robert J., Wimmer, Norbert, Kearns, Philip S., Thomas, Bradley G., Toth, Istvan, Brankov, Meliha and Rakoczy, P. Elizabeth (2004). Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Experimental Eye Research, 79 (4), 525-535. doi: 10.1016/j.exer.2004.06.023 |
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2004 Journal Article Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug deliveryRoss, Benjamin P., Braddy, April C., McGeary, Ross P., Blanchfield, Joanne T., Prokai, Laszlo and Toth, Istvan (2004). Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery. Molecular Pharmaceutics, 1 (3), 233-245. doi: 10.1021/mp049964d |
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2004 Journal Article Mucosal immunization: Adjuvants and delivery systemsMoyle, P.M., McGeary, R. P., Blanchfield, J. T. and Toth, I. (2004). Mucosal immunization: Adjuvants and delivery systems. Current Drug Delivery, 1 (4), 385-396. doi: 10.2174/1567201043334588 |
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2004 Journal Article Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide constructOlive, C., Batzloff, M., Horvath, A., Clair, T., Yarwood, P., Toth, I. and Good, M. F. (2004). Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct. Indian Journal of Medical Research, 119 (Suppl.), 88-94. |