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2006

Journal Article

Dde as a protecting group for carbohydrate synthesis

Bornaghi, L., Dekany, G., Drinnan, N. B., Taylor, S., Toth, I. and West, M. L. (2006). Dde as a protecting group for carbohydrate synthesis. Journal of Carbohydrate Chemistry, 25 (1), 1-18. doi: 10.1080/07328300500388685

Dde as a protecting group for carbohydrate synthesis

2006

Journal Article

Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide

Caccetta, R., Blanchfield, J. T., Harrison, J., Toth, I. and Benson, H. A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide. International Journal of Peptide Research and Therapeutics, 12 (3), 327-333. doi: 10.1007/s10989-006-9024-5

Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide

2006

Journal Article

Particulate systems as adjuvants and carriers for peptide and protein antigens

Liang, M T, Davies, N M, Blanchfield, J T and Toth, I (2006). Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery, 3 (4), 379-388. doi: 10.2174/156720106778559029

Particulate systems as adjuvants and carriers for peptide and protein antigens

2006

Journal Article

Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine

Moyle, P. M., Olive, C., Ho, M.-F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine. International Congress Series, 1289, 324-328. doi: 10.1016/j.ics.2005.11.084

Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine

2006

Journal Article

Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition

Parekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029

Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition

2006

Journal Article

Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A

White, Karen, Rades, Thomas, Kearns, Philip, Toth, Istvan and Hook, Sarah (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23 (7), 1473-1481. doi: 10.1007/s11095-006-0272-z

Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A

2006

Journal Article

Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin

Hayes, Patricia Y., Ross, Benjamin P., Thomas, Bradley G. and Toth, Istvan (2006). Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin. Bioorganic & Medicinal Chemistry, 14 (1), 143-152. doi: 10.1016/j.bmc.2005.08.004

Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin

2006

Journal Article

Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide

Everett, Ruth S., Vanhook, Miriam K., Barozzi, Nadia, Toth, Istvan and Johnson, Larry G. (2006). Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide. Molecular Pharmacology, 69 (2), 492-500. doi: 10.1124/mol.105.017251

Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide

2005

Journal Article

Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity

Marano, R. J., Toth, I., Wimmer, N., Brankov, M. and Rakoczy, E. P. (2005). Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Therapy, 12 (21), 1544-1550. doi: 10.1038/sj.gt.3302579

Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity

2005

Journal Article

Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers

Ross, B. P. and Toth, I. (2005). Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers. Current Drug Delivery, 2 (3), 277-287. doi: 10.2174/1567201054367968

Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers

2005

Journal Article

Functional implications of modifying RyR‐activating peptides for membrane permeability

Dulhunty, Angela F., Cengia, Louise, Young, Jacqui, Pace, Suzy M., Harvey, Peta J., Lamb, Graham D., Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan and Casarotto, Marco G. (2005). Functional implications of modifying RyR‐activating peptides for membrane permeability. British Journal of Pharmacology, 144 (6), 743-754. doi: 10.1038/sj.bjp.0705981

Functional implications of modifying RyR‐activating peptides for membrane permeability

2005

Journal Article

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

Johnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

2005

Journal Article

Versatile peptide dendrimers for nucleic acid delivery

Bayele, Henry, Sakthivel, T., O'Donell, Martin, Pasi, K. John, Wilderspin, Andrew F., Lee, Christine A., Toth, Istvan and Florence, Alexander T. (2005). Versatile peptide dendrimers for nucleic acid delivery. Journal of Pharmaceutical Sciences, 94 (2), 446-457. doi: 10.1002/jps.20230

Versatile peptide dendrimers for nucleic acid delivery

2005

Journal Article

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

Liang, M. T., Davies, N. M. and Toth, I. (2005). Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation. International Journal of Pharmaceutics, 301 (1-2), 247-254. doi: 10.1016/j.ijpharm.2005.06.010

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

2005

Journal Article

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

Blanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

2004

Journal Article

Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides

White, K., Kearns, P., Toth, I. and Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology And Cell Biology, 82 (5), 517-522. doi: 10.1111/j.1440-1711.2004.01269.x

Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides

2004

Journal Article

Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide

Marano, Robert J., Wimmer, Norbert, Kearns, Philip S., Thomas, Bradley G., Toth, Istvan, Brankov, Meliha and Rakoczy, P. Elizabeth (2004). Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Experimental Eye Research, 79 (4), 525-535. doi: 10.1016/j.exer.2004.06.023

Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide

2004

Journal Article

Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery

Ross, Benjamin P., Braddy, April C., McGeary, Ross P., Blanchfield, Joanne T., Prokai, Laszlo and Toth, Istvan (2004). Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery. Molecular Pharmaceutics, 1 (3), 233-245. doi: 10.1021/mp049964d

Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery

2004

Journal Article

Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage

Horvath, Anikó, Olive, Colleen, Karpati, Levente, Sun, H. K., Good, Hsien K. and Toth, Istvan (2004). Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage. Journal of Medicinal Chemistry, 47 (16), 4100-4104. doi: 10.1021/jm040041w

Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage

2004

Journal Article

Lipid, sugar and liposaccharide based delivery systems 2

Blanchfield, J. and Toth, I. (2004). Lipid, sugar and liposaccharide based delivery systems 2. Current Medicinal Chemistry, 11 (17), 2375-2382. doi: 10.2174/0929867043364621

Lipid, sugar and liposaccharide based delivery systems 2