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2007 Journal Article Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccinesMoyle, Peter M., Olive, Colleen, Ho, Mei-Fong, Pandey, Manisha, Dyer, Joanne, Suhrbier, Andreas, Fujita, Yoshio and Toth, Istvan (2007). Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry, 50 (19), 4721-4727. doi: 10.1021/jm070287b |
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2007 Journal Article The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella testBulmer, A., Ried, K., Coombes, J., Blanchfield, J., Toth, I. and Wagner, K. (2007). The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 629 (2), 122-132. doi: 10.1016/j.mrgentox.2007.01.008 |
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2007 Journal Article Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptideKoda, Y., Shiotani, K., Toth, I., Tsuda, Y., Okada, Y. and Blanchfield, J. (2007). Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide. Bioorganic & Medicinal Chemistry Letters, 17 (7), 2043-2046. doi: 10.1016/j.bmcl.2007.01.051 |
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2007 Journal Article Permeability studies of Kavalactones using a Caco-2 cell monolayer modelMatthias, A., Blanchfield, J., Penman, K., Bone, K., Toth, I. and Lehmann, R. (2007). Permeability studies of Kavalactones using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy and Therapeutics, 32 (3), 233-239. doi: 10.1111/j.1365-2710.2007.00810.x |
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2007 Journal Article Modified Influenza Virosomes: Recent Advances and Potential in Gene DeliveryKhoshnejad, M., Young, P. R., Toth, I. and Minchin, R. F. (2007). Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery. Current Medicinal Chemistry, 14 (29), 3152-3156. doi: 10.2174/092986707782793989 |
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2007 Journal Article A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes)Toth, I. (2007). A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes). Magyar kémikusok lapja, 62, 274-276. |
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2007 Journal Article Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulationOlive, C., Schulze, K., Sun, H. K., Ebensen, T., Horváth, A., Toth, I. and Guzman, C. A. (2007). Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation. Vaccine, 25 (10), 1789-1797. doi: 10.1016/j.vaccine.2006.11.031 |
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2007 Journal Article Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolaseKim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057 |
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2006 Journal Article Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical LigationMoyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p |
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2006 Journal Article Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M proteinOlive, Colleen, Sun, Hsien Kuo, Ho, Mei‐Fong, Dyer, Joanne, Horvath, Aniko, Toth, Istvan and Good, Michael F. (2006). Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein. Journal of Infectious Diseases, 194 (3), 316-324. doi: 10.1086/505580 |
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2006 Journal Article Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo functionAmon, Michael A., Ali, Marina, Bender, Vera, Chan, Yiu-Ngok, Toth, Istvan and Manolios, Nicholas (2006). Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo function. Biochimica Et Biophysica Acta-molecular Cell Research, 1763 (8), 879-888. doi: 10.1016/j.bbamcr.2006.04.013 |
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2006 Journal Article Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcusOlive, Colleen, Ho, Mei‐Fong, Dyer, Joanne, Lincoln, Douglas, Barozzi, Nadia, Toth, Istvan and Good, Michael F. (2006). Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus. Journal of Infectious Diseases, 193 (12), 1666-1676. doi: 10.1086/504266 |
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2006 Journal Article The lipid core peptide system in vaccine deliveryToth, Istvan, Moyle, Peter, Karpati, Levente, Horvath, Aniko, Olive, Colleen and Good, Michael (2006). The lipid core peptide system in vaccine delivery. International Congress Series, 1289, 307-310. doi: 10.1016/j.ics.2005.11.057 |
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2006 Journal Article Dde as a protecting group for carbohydrate synthesisBornaghi, L., Dekany, G., Drinnan, N. B., Taylor, S., Toth, I. and West, M. L. (2006). Dde as a protecting group for carbohydrate synthesis. Journal of Carbohydrate Chemistry, 25 (1), 1-18. doi: 10.1080/07328300500388685 |
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2006 Journal Article Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptideCaccetta, R., Blanchfield, J. T., Harrison, J., Toth, I. and Benson, H. A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide. International Journal of Peptide Research and Therapeutics, 12 (3), 327-333. doi: 10.1007/s10989-006-9024-5 |
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2006 Journal Article Particulate systems as adjuvants and carriers for peptide and protein antigensLiang, M T, Davies, N M, Blanchfield, J T and Toth, I (2006). Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery, 3 (4), 379-388. doi: 10.2174/156720106778559029 |
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2006 Journal Article Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccineMoyle, P. M., Olive, C., Ho, M.-F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine. International Congress Series, 1289, 324-328. doi: 10.1016/j.ics.2005.11.084 |
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2006 Journal Article Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibitionParekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029 |
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2006 Journal Article Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil AWhite, Karen, Rades, Thomas, Kearns, Philip, Toth, Istvan and Hook, Sarah (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23 (7), 1473-1481. doi: 10.1007/s11095-006-0272-z |
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2006 Journal Article Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparinHayes, Patricia Y., Ross, Benjamin P., Thomas, Bradley G. and Toth, Istvan (2006). Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin. Bioorganic & Medicinal Chemistry, 14 (1), 143-152. doi: 10.1016/j.bmc.2005.08.004 |
