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2021

Journal Article

Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptides

Khatun, Farjana, Dai, Charles C., Rivera-Hernandez, Tania, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2021). Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptides. ACS Infectious Diseases, 7 (2) acsinfecdis.0c00722, 390-405. doi: 10.1021/acsinfecdis.0c00722

Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptides

2021

Journal Article

Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery

Azuar, Armira, Li, Zhuoqing, Shibu, Mohini A., Zhao, Lili, Luo, Yacheng, Shalash, Ahmed O., Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery. Journal of Medicinal Chemistry, 64 (5) acs.jmedchem.0c01660, 2648-2658. doi: 10.1021/acs.jmedchem.0c01660

Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery

2021

Journal Article

A global review on short peptides: frontiers and perspectives

Apostolopoulos, Vasso, Bojarska, Joanna, Chai, Tsun-Thai, Elnagdy, Sherif, Kaczmarek, Krzysztof, Matsoukas, John, New, Roger, Parang, Keykavous, Lopez, Octavio Paredes, Parhiz, Hamideh, Perera, Conrad O., Pickholz, Monica, Remko, Milan, Saviano, Michele, Skwarczynski, Mariusz, Tang, Yefeng, Wolf, Wojciech M., Yoshiya, Taku, Zabrocki, Janusz, Zielenkiewicz, Piotr, AlKhazindar, Maha, Barriga, Vanessa, Kelaidonis, Konstantinos, Sarasia, Elham Mousavinezhad and Toth, Istvan (2021). A global review on short peptides: frontiers and perspectives. Molecules, 26 (2) 430, 430. doi: 10.3390/molecules26020430

A global review on short peptides: frontiers and perspectives

2021

Journal Article

A potent vaccine delivery system

Zhao, Guangzu, Azuar, Armira, Toth, Istvan and Skwarczynski, Mariusz (2021). A potent vaccine delivery system. Bio-protocol, 11 (7) e3973, e3973. doi: 10.21769/bioprotoc.3973

A potent vaccine delivery system

2021

Journal Article

Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2

Pandey, Manisha, Ozberk, Victoria, Eskandari, Sharareh, Shalash, Ahmed O., Joyce, Michael A., Saffran, Holly A., Day, Christopher J., Lepletier, Ailin, Spillings, Belinda L., Mills, Jamie-Lee, Calcutt, Ainslie, Fan, Fan, Williams, James T., Stanisic, Danielle I., Hattingh, Laetitia, Gerrard, John, Skwarczynski, Mariusz, Mak, Johnson, Jennings, Michael P., Toth, Istvan, Tyrrell, D. Lorne and Good, Michael F. (2021). Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2. Clinical and Translational Immunology, 10 (3) e1260, e1260. doi: 10.1002/cti2.1260

Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2

2021

Book Chapter

Peptide-Polymer Conjugation Via Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition

Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Peptide-Polymer Conjugation Via Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition. Methods in Molecular Biology. (pp. 1-7) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-1617-8_1

Peptide-Polymer Conjugation Via Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition

2021

Book

Peptide Conjugation : Methods and Protocols

Hussein, Waleed M., Stephenson, Rachel J. and Toth, Istvan eds. (2021). Peptide Conjugation : Methods and Protocols. Methods in Molecular Biology, New York, NY United States: Springer. doi: 10.1007/978-1-0716-1617-8

Peptide Conjugation : Methods and Protocols

2021

Book Chapter

Double conjugation using mercapto-acryloyl and alkyne-azide reactions for the synthesis of branched multiantigenic vaccine candidates

Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Double conjugation using mercapto-acryloyl and alkyne-azide reactions for the synthesis of branched multiantigenic vaccine candidates. Peptide conjugation: methods and protocols. (pp. 141-150) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-1617-8_13

Double conjugation using mercapto-acryloyl and alkyne-azide reactions for the synthesis of branched multiantigenic vaccine candidates

2021

Book Chapter

Nanocarrier-based vaccine delivery systems for synthetic peptide vaccines

Madge, Harrison Y.R., Stephenson, Rachel J. and Toth, Istvan (2021). Nanocarrier-based vaccine delivery systems for synthetic peptide vaccines. Handbook of nanotechnology applications: environment, energy, agriculture and medicine. (pp. 509-535) edited by Woei Jye Lau, Kajornsak Faungnawakij, Kuakoon Piyachomkwan and Uracha Rungsardthong Ruktanonchai. Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-821506-7.00020-x

Nanocarrier-based vaccine delivery systems for synthetic peptide vaccines

2021

Journal Article

Lipoamino acid-modified GnRH analogs with receptor-mediated antiproliferative activity in prostate and ovarian cancer cells

Varamini, Pegah, Dhiman, Kimmi, Khazeni, Sepideh, Mansfeld, Frieda and Toth, Istvan (2021). Lipoamino acid-modified GnRH analogs with receptor-mediated antiproliferative activity in prostate and ovarian cancer cells. Medicinal Chemistry Research, 30 (8), 1577-1587. doi: 10.1007/s00044-021-02755-0

Lipoamino acid-modified GnRH analogs with receptor-mediated antiproliferative activity in prostate and ovarian cancer cells

2021

Book Chapter

Preface

Hussein, Waleed H., Stephenson, Rachel J. and Toth, Istvan (2021). Preface. Peptide conjugation: methods and protocols. (pp. v-v) New York, NY USA: Humana Press.

Preface

2021

Book Chapter

Peptide-pegylated lipid conjugation via copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition

Hussein, Waleed M. and Toth, Istvan (2021). Peptide-pegylated lipid conjugation via copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition. Peptide conjugation: methods and protocols. (pp. 57-64) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-1617-8_6

Peptide-pegylated lipid conjugation via copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition

2020

Journal Article

A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes

Zhao, Lili, Yang, Jieru, Nahar, Ummey Jannatun, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes. Bioorganic and Medicinal Chemistry, 28 (24) 115823, 115823. doi: 10.1016/j.bmc.2020.115823

A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes

2020

Journal Article

Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19)

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2020). Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19). mBio, 11 (6) e02995-20, 1-1. doi: 10.1128/mBio.02995-20

Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19)

2020

Journal Article

Carbohydrate immune adjuvants in subunit vaccines

Bashiri, Sahra, Koirala, Prashamsa, Toth, Istvan and Skwarczynski, Mariusz (2020). Carbohydrate immune adjuvants in subunit vaccines. Pharmaceutics, 12 (10) 965, 965-33. doi: 10.3390/pharmaceutics12100965

Carbohydrate immune adjuvants in subunit vaccines

2020

Journal Article

Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus

Dai, Charles C., Yang, Jieru, Hussein, Waleed M., Zhao, Lili, Wang, Xiumin, Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus. ACS Infectious Diseases, 6 (9) acsinfecdis.0c00452, 2502-2512. doi: 10.1021/acsinfecdis.0c00452

Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus

2020

Journal Article

Progress in the development of subunit vaccines against malaria

Skwarczynski, Mariusz, Chandrudu, Saranya, Rigau-Planella, Berta, Islam, Md. Tanjir, Cheong, Yee S., Liu, Genan, Wang, Xiumin, Toth, Istvan and Hussein, Waleed M. (2020). Progress in the development of subunit vaccines against malaria. Vaccines, 8 (3) 373, 1-19. doi: 10.3390/vaccines8030373

Progress in the development of subunit vaccines against malaria

2020

Journal Article

Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein

Dai, Chuankai, Khalil, Zeinab G., Hussein, Waleed M., Yang, Jieru, Wang, Xiumin, Zhao, Lili, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein. Vaccines, 8 (2) 210, 210. doi: 10.3390/vaccines8020210

Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein

2020

Journal Article

Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens

Madge, Harrison Y. R., Sharma, Hansa, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert John, Toth, Istvan and Stephenson, Rachel (2020). Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens. Journal of Medicinal Chemistry, 63 (10) acs.jmedchem.0c00203, 5387-5397. doi: 10.1021/acs.jmedchem.0c00203

Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens

2020

Journal Article

Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus

Zhao, Lili, Jin, Wanli, Cruz, Jazmina Gonzalez, Marasini, Nirmal, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus. Nanomaterials, 10 (5) 823, 823. doi: 10.3390/nano10050823

Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus