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2015

Journal Article

A novel transducible chimeric phage from Escherichia coli O157: H7 Sakai strain encoding Stx1 production

Sváb, Domonkos, Bálint, Balázs, Maróti, Gergely and Tóth, István (2015). A novel transducible chimeric phage from Escherichia coli O157: H7 Sakai strain encoding Stx1 production. Infection, Genetics and Evolution, 29, 42-47. doi: 10.1016/j.meegid.2014.10.019

A novel transducible chimeric phage from Escherichia coli O157: H7 Sakai strain encoding Stx1 production

2015

Journal Article

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains

Azmi, Fazren, Elliott, Alysha G., Khalil, Zeinab G., Hussein, Waleed M., Kavanagh, Angela, Huang, Johnny X., Quezada, Michelle, Blaskovich, Mark A. T., Capon, Robert J., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2015). Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains. Nanomedicine, 10 (22), 3359-3371. doi: 10.2217/nnm.15.137

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains

2015

Journal Article

Self-adjuvanting therapeutic peptide-based vaccine induce CD8+ cytotoxic T lymphocyte responses in a murine human papillomavirus tumor model

Liu, Tzu-Yu, Giddam, Ashwini Kumar, Hussein, Waleed M., Jia, Zhongfan, McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2015). Self-adjuvanting therapeutic peptide-based vaccine induce CD8+ cytotoxic T lymphocyte responses in a murine human papillomavirus tumor model. Current Drug Delivery, 12 (1), 3-8. doi: 10.2174/1567201811666141001155729

Self-adjuvanting therapeutic peptide-based vaccine induce CD8+ cytotoxic T lymphocyte responses in a murine human papillomavirus tumor model

2015

Journal Article

Meet our editorial board member

Toth, Istvan (2015). Meet our editorial board member. Current Drug Delivery, 12 (2), 121-121. doi: 10.2174/156720181202150423103624

Meet our editorial board member

2014

Journal Article

Biophysical characterization of lectin-glycan interactions for therapeutics, vaccines and targeted drug-delivery.

Christie, Michelle P., Toth, Istvan and Simerska, Pavla (2014). Biophysical characterization of lectin-glycan interactions for therapeutics, vaccines and targeted drug-delivery.. Future Medicinal Chemistry, 6 (18), 2113-2129. doi: 10.4155/fmc.14.130

Biophysical characterization of lectin-glycan interactions for therapeutics, vaccines and targeted drug-delivery.

2014

Journal Article

Recent advances in peptide-based subunit nanovaccines

Skwarczynski, Mariusz and Toth, Istvan (2014). Recent advances in peptide-based subunit nanovaccines. Nanomedicine, 9 (17), 2657-2669. doi: 10.2217/nnm.14.187

Recent advances in peptide-based subunit nanovaccines

2014

Journal Article

The contribution of non-human primate models to the development of human vaccines

Rivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014). The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 (101), 313-322.

The contribution of non-human primate models to the development of human vaccines

2014

Journal Article

Enhanced transdermal peptide delivery and stability by lipid conjugation: epidermal permeation, stereoselectivity and mechanistic insights

Namjoshi, Sarika, Toth, Istvan, Blanchfield, Joanne T., Trotter, Nicholas, Mancera, Ricardo L. and Benson, Heather A. E. (2014). Enhanced transdermal peptide delivery and stability by lipid conjugation: epidermal permeation, stereoselectivity and mechanistic insights. Pharmaceutical Research, 31 (12), 3304-3312. doi: 10.1007/s11095-014-1420-5

Enhanced transdermal peptide delivery and stability by lipid conjugation: epidermal permeation, stereoselectivity and mechanistic insights

2014

Journal Article

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

Zaman, Mehfuz, Chandrudu, Saranya, Giddam, Ashwini K., Reiman, Jennifer, Skwarczynski, Mariusz, McPhun, Virginia, Moyle, Peter M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity. Nanomedicine, 9 (17), 2613-2624. doi: 10.2217/NNM.14.190

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

2014

Journal Article

Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant

Azmi, Fazren, Ahmad Fuaad, Abdullah Al Hadi, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2014). Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant. Bioorganic and Medicinal Chemistry, 22 (22), 6401-6408. doi: 10.1016/j.bmc.2014.09.042

Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant

2014

Journal Article

Stability, Permeability and Growth-Inhibitory Properties of Gonadotropin-Releasing Hormone Liposaccharides

Goodwin, Daryn, Varamini, Pegah, Simerska, Pavla and Toth, Istvan (2014). Stability, Permeability and Growth-Inhibitory Properties of Gonadotropin-Releasing Hormone Liposaccharides. Pharmaceutical Research, 32 (5), 1570-1584. doi: 10.1007/s11095-014-1558-1

Stability, Permeability and Growth-Inhibitory Properties of Gonadotropin-Releasing Hormone Liposaccharides

2014

Journal Article

Targeting the mannose receptor with mannosylated subunit vaccines

Sedaghat, B., Stephenson, R. and Toth, I. (2014). Targeting the mannose receptor with mannosylated subunit vaccines. Current Medicinal Chemistry, 21 (30), 3405-3418. doi: 10.2174/0929867321666140826115552

Targeting the mannose receptor with mannosylated subunit vaccines

2014

Journal Article

Schistosome vaccine adjuvants in preclinical and clinical research

Stephenson, Rachel, You, Hong, McManus, Donald P. and Toth, Istvan (2014). Schistosome vaccine adjuvants in preclinical and clinical research. Vaccines, 2 (3), 654-685. doi: 10.3390/vaccines2030654

Schistosome vaccine adjuvants in preclinical and clinical research

2014

Journal Article

Active immunisation of mice with GnRH lipopeptide vaccine candidates: importance of T helper or multi-dimer GnRH epitope

Goodwin, Daryn, Simerska, Pavla, Chang, Cheng-Hung, Mansfeld, Friederike M., Varamini, Pegah, D'Occhio, Michael J. and Toth, Istvan (2014). Active immunisation of mice with GnRH lipopeptide vaccine candidates: importance of T helper or multi-dimer GnRH epitope. Bioorganic and Medicinal Chemistry, 22 (17), 4848-4854. doi: 10.1016/j.bmc.2014.06.052

Active immunisation of mice with GnRH lipopeptide vaccine candidates: importance of T helper or multi-dimer GnRH epitope

2014

Conference Publication

Glycosylation of Luteinizing Hormone Releasing Hormone: Towards the Development of Orally Active Peptides

Moradi, S. V., Varamini, P. and Toth, I. (2014). Glycosylation of Luteinizing Hormone Releasing Hormone: Towards the Development of Orally Active Peptides. HOBOKEN: WILEY.

Glycosylation of Luteinizing Hormone Releasing Hormone: Towards the Development of Orally Active Peptides

2014

Journal Article

The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: contributions of glucose transporters and efflux systems

Moradi, Shayli Varasteh, Varamini, Pegah and Toth, Istvan (2014). The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: contributions of glucose transporters and efflux systems. Journal of Pharmaceutical Sciences, 103 (10), 3217-3224. doi: 10.1002/jps.24120

The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: contributions of glucose transporters and efflux systems

2014

Journal Article

Oral delivery of nanoparticle-based vaccines

Marasini, Nirmal, Skwarczynski, Mariusz and Toth, Istvan (2014). Oral delivery of nanoparticle-based vaccines. Expert Review of Vaccines, Early Online (11), 1361-1376. doi: 10.1586/14760584.2014.936852

Oral delivery of nanoparticle-based vaccines

2014

Journal Article

Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro

Stephenson, Rachel, Varamini, Pegah, Butcher, Neville, Minchin, Rodney and Toth, Istvan (2014). Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro. Nanomedicine: Nanotechnology, Biology and Medicine, 10 (8), 1799-1808. doi: 10.1016/j.nano.2014.06.015

Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro

2014

Journal Article

Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold

Fagan, Vincent, Toth, Istvan and Simerska, Pavla (2014). Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold. Beilstein Journal of Organic Chemistry, 10 (1), 1741-1748. doi: 10.3762/bjoc.10.181

Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold

2014

Journal Article

Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines

Moyle, Peter M., Dai, Wei, Zhang, Yingkai, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines. Bioconjugate Chemistry, 25 (5), 965-978. doi: 10.1021/bc500108b

Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines