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2018

Conference Publication

Predictability of the 12-week dosing status at Week 48 for patients receiving brolucizumab in HAWK and HARRIER

Dugel, Pravin U., Lang, Gabriele Elisabeth, Razavi, Sam, Weichselberger, Andreas, Ogura, Yuichiro and Brown, David M. (2018). Predictability of the 12-week dosing status at Week 48 for patients receiving brolucizumab in HAWK and HARRIER. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu Hi, Apr 21-May 03, 2018. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.

Predictability of the 12-week dosing status at Week 48 for patients receiving brolucizumab in HAWK and HARRIER

2018

Conference Publication

Fluocinolone acetonide ( FAc) 0.2 mg intravitreal implant in the treatment of diabetic macular edema (DME)

Liu, John, Coney, Joseph, Schartman, Jerome, Miller, David G., Zegarra, Hernando and Rao, Llewelyn (2018). Fluocinolone acetonide ( FAc) 0.2 mg intravitreal implant in the treatment of diabetic macular edema (DME). Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu Hi, Apr 21-May 03, 2018. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.

Fluocinolone acetonide ( FAc) 0.2 mg intravitreal implant in the treatment of diabetic macular edema (DME)

2018

Conference Publication

Intravitreal Aflibercept Injection (IAI) for Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR): The Phase 3 PANORAMA Study

Brown, David M. (2018). Intravitreal Aflibercept Injection (IAI) for Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR): The Phase 3 PANORAMA Study. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu Hi, Apr 21-May 03, 2018. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.

Intravitreal Aflibercept Injection (IAI) for Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR): The Phase 3 PANORAMA Study

2018

Conference Publication

Suprachoroidal Space Alterations after Delivery of Triamcinolone Acetonide: Post-Hoc Analysis of the Phase 1/2 HULK Study of Patients with Diabetic Macular Edema

Lampen, Shaun Ian Retief, Khurana, Rahul N., Brown, David M. and Wykoff, Charles Clifton (2018). Suprachoroidal Space Alterations after Delivery of Triamcinolone Acetonide: Post-Hoc Analysis of the Phase 1/2 HULK Study of Patients with Diabetic Macular Edema. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu Hi, Apr 21-May 03, 2018. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.

Suprachoroidal Space Alterations after Delivery of Triamcinolone Acetonide: Post-Hoc Analysis of the Phase 1/2 HULK Study of Patients with Diabetic Macular Edema

2018

Conference Publication

Dermatopathologic and Optical Coherence Tomography "Cracked Mud Sign" in Pseudoxanthoma Elasticum

Brown, Ashley E., Wykoff, Charles Clifton, Hsu, Sylvia and Brown, David M. (2018). Dermatopathologic and Optical Coherence Tomography "Cracked Mud Sign" in Pseudoxanthoma Elasticum. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu Hi, Apr 21-May 03, 2018. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.

Dermatopathologic and Optical Coherence Tomography "Cracked Mud Sign" in Pseudoxanthoma Elasticum

2018

Conference Publication

Clinical Study of Squalamine Lactate Ophthalmic Solution 0.2% in Combination with Ranibizumab Compared to Ranibizimab Monotherapy in Treatment Naive Neovascular Age-Related Macular DegenerationClinical Study of Squalamine Lactate Ophthalmic Solution 0.2% in Combination with Ranibizumab Compared to Ranibizimab Monotherapy in Treatment Naive Neovascular Age-Related Macular Degeneration

Elman, Michael J., Brown, David M., Kaiser, Peter K. and Slakter, Jason S. (2018). Clinical Study of Squalamine Lactate Ophthalmic Solution 0.2% in Combination with Ranibizumab Compared to Ranibizimab Monotherapy in Treatment Naive Neovascular Age-Related Macular DegenerationClinical Study of Squalamine Lactate Ophthalmic Solution 0.2% in Combination with Ranibizumab Compared to Ranibizimab Monotherapy in Treatment Naive Neovascular Age-Related Macular Degeneration. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu Hi, Apr 21-May 03, 2018. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.

Clinical Study of Squalamine Lactate Ophthalmic Solution 0.2% in Combination with Ranibizumab Compared to Ranibizimab Monotherapy in Treatment Naive Neovascular Age-Related Macular DegenerationClinical Study of Squalamine Lactate Ophthalmic Solution 0.2% in Combination with Ranibizumab Compared to Ranibizimab Monotherapy in Treatment Naive Neovascular Age-Related Macular Degeneration

2018

Conference Publication

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic disease

Beaumont, Robin N., Warrington, Nicole M., Horikoshi, Momoko, Day, Felix R., Ong, Ken K., McCarthy, Mark I., Perry, John R. B., Freathy, Rachel M. and Evans, David M. (2018). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic disease. 27th Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), San Diego, Ca, United States, 14-16 October 2018. Hoboken, NJ, United States: John Wiley & Sons.

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic disease

2018

Conference Publication

The genetic architecture of hip statistical shape models suggests that endochondral bone formation makes an important contribution to hip shape

Baird, D., Evans, D. S., Gregory, J. S., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Aspden, R. M., Kamanu, F. K., Kiel, D. P., Orwoll, E. S., Cummings, S. R., Lane, N. E., Mullins, B. H., Williams, F. M., Richards, B., Wilson, S. G., Spector, T. D., Faber, B. G., Lawlor, D. A., Beck, T. J., Evans, D. M., Paternoster, L., Karasikl, D. and Tobias, J. H. (2018). The genetic architecture of hip statistical shape models suggests that endochondral bone formation makes an important contribution to hip shape. OARSI World Congress on Osteoarthritis - Promoting Clinical and Basic Research in Osteoarthritis, Liverpool, England, 26-29 April 2018. London, United Kingdom: Elsevier.

The genetic architecture of hip statistical shape models suggests that endochondral bone formation makes an important contribution to hip shape

2018

Conference Publication

An Atlas of Human and Murine Genetic Influences on Osteoporosis

Morris, John, Kemp, John, Youlten, Scott, Logan, John, Chai, Ryan, Vulpescu, Nicholas, Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu, Sergio, Marcelo, Medina-Gomez, Carolina, Trajanoska, Katerina, Quinn, Julian, Ghirardello, Elena, Butterfield, Natalie, Curry, Katharine, Leitch, Victoria, Sparkes, Penny, Laurent, Laetitia, Adoum, Anne-Tounsia, Mannan, Naila, Komla-Ebri, Davide, Pollard, Andrea, Dewhurst, Hannah, Kaptoge, Stephen, Baldock, Paul, Cooper, Cyrus, Reeve, Jonathan, Ntzani, Evangelia ... Richards, Brent (2018). An Atlas of Human and Murine Genetic Influences on Osteoporosis. Annual Meeting of the American Society for Bone and Mineral Research, Montreal, Canada, 28 September - 1 October, 2018. Hoboken, NJ United States: Wiley-Blackwell Publishing. doi: 10.1002/jbmr.3621

An Atlas of Human and Murine Genetic Influences on Osteoporosis

2017

Conference Publication

Small cell lung carcinoma (SCLC) cell line screen of standard of care (etoposide/carboplatin) plus a third agent

Teicher, Beverly A., Selby, Michael, Silvers, Thomas, Laudeman, Julie, Reinhart, Russell, Delosh, Rene, Ogle, Chad, Parchment, Ralph, Krushkal, Julia, Sonkin, Dmitriy, Morris, Joel, Kunkel, Mark and Evans, David (2017). Small cell lung carcinoma (SCLC) cell line screen of standard of care (etoposide/carboplatin) plus a third agent. Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington Dc, Apr 01-05, 2017. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2017-4831

Small cell lung carcinoma (SCLC) cell line screen of standard of care (etoposide/carboplatin) plus a third agent

2017

Conference Publication

A clinical pharmacodynamic biomarker assay that distinguishes potentially repairable, cytotoxic drug-induced DNA double strand breaks (DSBs) from DSBs associated with apoptotic cell death

Dull, Angie B., Wilsker, Deborah, Kinders, Robert J., Parchment, Ralph E., Evans, David, Teicher, Beverly A. and Doroshow, James H. (2017). A clinical pharmacodynamic biomarker assay that distinguishes potentially repairable, cytotoxic drug-induced DNA double strand breaks (DSBs) from DSBs associated with apoptotic cell death. Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington Dc, Apr 01-05, 2017. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2017-3072

A clinical pharmacodynamic biomarker assay that distinguishes potentially repairable, cytotoxic drug-induced DNA double strand breaks (DSBs) from DSBs associated with apoptotic cell death

2017

Conference Publication

Comparison of the response of the NCI60 NSCLC panel with the response of patient-derived NSCLC lines to approved and investigational agents

Teicher, Beverly A., Evans, David, Silvers, Thomas, Selby, Michael, Delosh, Rene, Laudeman, Julie, Ogle, Chad, Reinhart, Russell, Morris, Joel, Kaur, Gurmeet and Doroshow, James (2017). Comparison of the response of the NCI60 NSCLC panel with the response of patient-derived NSCLC lines to approved and investigational agents. Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington Dc, Apr 01-05, 2017. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2017-348

Comparison of the response of the NCI60 NSCLC panel with the response of patient-derived NSCLC lines to approved and investigational agents

2017

Conference Publication

Developmental changes in genetic relationships between traits and disease: Analyses of genetic overlaps between social-communication difficulties, autism spectrum disorders and schizophrenia

St Pourcain, Beate, Robinson, Elise, Bulik-Sullivan, Brendan, Anttila, Verneri, Maller, Julian, Skuse, David, Rings, Susan, Evans, David, Timpson, Nicholas, Ronald, Angelica, Grove, Jakob, Borglum, Anders, Mortensen, Preben Bo, Daly, Mark and Smiths, George Davey (2017). Developmental changes in genetic relationships between traits and disease: Analyses of genetic overlaps between social-communication difficulties, autism spectrum disorders and schizophrenia. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, Oct 16-20 2015. Amsterdam, Netherlands: Elsevier.

Developmental changes in genetic relationships between traits and disease: Analyses of genetic overlaps between social-communication difficulties, autism spectrum disorders and schizophrenia

2017

Conference Publication

Genome-wide association study identifies three novel genetic determinants of dental maturation

Grgic, Olja, Medina-Gomez, Carolina, Dhamo, Brunilda, Trajanoska, Katerina, Vucic, Strahinja, Ongkosuwito, Edwin M., Jaddoe, Vincent W. V., Uitterlinden, Andre G., Jarvelin, Marjo-Riitta, Timpson, Nicholas, Evans, David M., Wolvius, Eppo B. and Rivadeneira, Fernando (2017). Genome-wide association study identifies three novel genetic determinants of dental maturation. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Denver, CO USA, 8-11 September 2017. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Genome-wide association study identifies three novel genetic determinants of dental maturation

2017

Conference Publication

Estimating developmental changes within the genetic architecture of social communication traits: a multivariate study of genetic variance in unrelated individuals

St Pourcain, Beate, Eaves, Lindon, Verhoef, Ellen, Shapland, Chin Yang, Ring, Susan M., Fisher, Simon E., Medland, Sarah, Evans, David and Smith, George Davey (2017). Estimating developmental changes within the genetic architecture of social communication traits: a multivariate study of genetic variance in unrelated individuals. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, Jun 28-Jul 01, 2017. New York, NY, United States: Springer.

Estimating developmental changes within the genetic architecture of social communication traits: a multivariate study of genetic variance in unrelated individuals

2017

Conference Publication

Performing Mendelian randomization using structural equation models

Evans, David and Warrington, Nicole (2017). Performing Mendelian randomization using structural equation models. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, 28 June - 1 July 2017. New York NY United States: Springer.

Performing Mendelian randomization using structural equation models

2017

Conference Publication

Trait-specific patterns of common genetic factors influence social-communication difficulties and ADHD symptoms during child and adolescent development

St Pourcain, Beate, Eaves, Lindon, Evans, David M., Stergiakouli, Evie, Fisher, Simon E., Ring, Susan M., Carey, Gregory and George, Davey Smith (2017). Trait-specific patterns of common genetic factors influence social-communication difficulties and ADHD symptoms during child and adolescent development. 24th World Congress of Psychiatric Genetics (WCPG), Jerusalem Israel, October 30 - November 4 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2016.09.411

Trait-specific patterns of common genetic factors influence social-communication difficulties and ADHD symptoms during child and adolescent development

2017

Conference Publication

Genome-wide association study of extreme high bone mass identifies NPR3 as a novel BMD-associated gene and highlights the contribution of common genetic variation to extreme BMD phenotypes

Gregson, Celia, Newell, Felicity, Leo, Paul, Paternoster, Lavinia, Marshall, Mhairi, Clark, Graeme, Morris, John, Ge, Bing, Bao, Xiao, Bassett, Duncan, Williams, Graham, Youlten, Scott, Croucher, Peter, Smith, George Davey, Evans, David, Kemp, John, Brown, Matthew, Tobias, Jon and Duncan, Emma (2017). Genome-wide association study of extreme high bone mass identifies NPR3 as a novel BMD-associated gene and highlights the contribution of common genetic variation to extreme BMD phenotypes. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Denver CO, United States, 8-11 September 2017. Hoboken, NJ United States: Wiley.

Genome-wide association study of extreme high bone mass identifies NPR3 as a novel BMD-associated gene and highlights the contribution of common genetic variation to extreme BMD phenotypes

2017

Conference Publication

Genetic links between social-communication traits, ADHD traits and clinical ADHD during development

St Pourcain, Beate, Martin, Joanna, Stergiakouli, Evie, Robinson, Elise, Skuse, David, Susan, Ring, Ronald, Angelica, Evans, David, Timpson, Nicholas, Thapar, Anita and Smith, George Davey (2017). Genetic links between social-communication traits, ADHD traits and clinical ADHD during development. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, Oct 16-20 2015. Amsterdam, Netherlands: Elsevier.

Genetic links between social-communication traits, ADHD traits and clinical ADHD during development

2017

Conference Publication

Common polygenic risk for ASD and ADHD is associated with childhood linguistic traits within the general population, but with opposite effects

St Pourcain, Beate, Verhoef, Ellen, Fisher, Simon E., Stergiakouli, Evie, Evans, David E., Ring, Susan M. and Smith, George Davey (2017). Common polygenic risk for ASD and ADHD is associated with childhood linguistic traits within the general population, but with opposite effects. 24th World Congress of Psychiatric Genetics (WCPG), Jerusalem Israel, October 30-November 4 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2016.09.470

Common polygenic risk for ASD and ADHD is associated with childhood linguistic traits within the general population, but with opposite effects