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2018 Journal Article Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathwaysDuffy, David L., Zhu, Gu, Li, Xin, Sanna, Marianna, Iles, Mark M., Jacobs, Leonie C., Evans, David M., Yazar, Seyhan, Beesley, Jonathan, Law, Matthew H., Kraft, Peter, Visconti, Alessia, Taylor, John C., Lui, Fan, Wright, Margaret J., Henders, Anjali K., Bowdler, Lisa, Glass, Dan, Ikram, Arfan M., Uitterlinden, André G., Madden, Pamela A., Heath, Andrew C., Nelson, Elliot C., Green, Adele C., Chanock, Stephen, Barrett, Jennifer H., Brown, Matthew A., Hayward, Nicholas K., MacGregor, Stuart ... Martin, Nicholas G. (2018). Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature Communications, 9 (1) 4774, 4774. doi: 10.1038/s41467-018-06649-5 |
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2018 Journal Article Imputation-based analysis of MICA alleles in the susceptibility to ankylosing spondylitisCortes, Adrian, Gladman, Dafna, Raychaudhuri, Soumya, Cui, Jing, Wheeler, Lawrie, Brown, Matthew A., International Genetics of Ankylosing Spondylitis Consortium (IGAS) and Evans, David (2018). Imputation-based analysis of MICA alleles in the susceptibility to ankylosing spondylitis. Annals of the Rheumatic Diseases, 77 (11), 1691-1692. doi: 10.1136/annrheumdis-2018-213413 |
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2018 Journal Article Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disordersLigthart, Symen, Vaez, Ahmad, Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Prins, Bram P., Van der Most, Peter J., Tanaka, Toshiko, Naderi, Elnaz, Rose, Lynda M., Wu, Ying, Karlsson, Robert, Barbalic, Maja, Lin, Honghuang, Pool, René, Zhu, Gu, Macé, Aurélien, Sidore, Carlo, Trompet, Stella, Mangino, Massimo, Sabater-Lleal, Maria, Kemp, John P., Abbasi, Ali, Kacprowski, Tim, Verweij, Niek, Smith, Albert V., Huang, Tao, Marzi, Carola, Feitosa, Mary F. ... Alizadeh, Behrooz Z. (2018). Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders. American Journal of Human Genetics, 103 (5), 691-706. doi: 10.1016/j.ajhg.2018.09.009 |
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2018 Journal Article Identification of novel loci associated with hip shape: a meta-analysis of genomewide association studiesBaird, Denis A., Evans, Daniel S., Kamanu, Frederick K., Gregory, Jennifer S., Saunders, Fiona R., Giuraniuc, Claudiu V., Barr, Rebecca J., Aspden, Richard M., Jenkins, Deborah, Kiel, Douglas P., Orwoll, Eric S., Cummings, Steven R., Lane, Nancy E., Mullin, Benjamin H., Williams, Frances M. K., Richards, J Brent, Wilson, Scott G., Spector, Tim D., Faber, Benjamin G., Lawlor, Deborah A., Grundberg, Elin, Ohlsson, Claes, Pettersson-Kymmer, Ulrika, Capellini, Terence D., Richard, Daniel, Beck, Thomas J., Evans, David M., Paternoster, Lavinia, Karasik, David and Tobias, Jonathan H. (2018). Identification of novel loci associated with hip shape: a meta-analysis of genomewide association studies. Journal of Bone and Mineral Research, 34 (2), 241-251. doi: 10.1002/jbmr.3605 |
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2018 Other Outputs Machine Learning to Predict Osteoporotic Fracture Risk from GenotypesForgetta, Vincenzo, Keller-Baruch, Julyan, Forest, Marie, Durand, Audrey, Bhatnagar, Sahir, Kemp, John, Morris, John A, Kanis, John A, Kiel, Douglas P., McCloskey, Eugene V, Rivadeneira, Fernando, Johannson, Helena, Harvey, Nicholas, Cooper, Cyrus, Evans, David M, Pineau, Joelle, Leslie, William D, Greenwood, Celia MT and Richards, J Brent (2018). Machine Learning to Predict Osteoporotic Fracture Risk from Genotypes. doi: 10.1101/413716 |
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2018 Journal Article Genome-wide association study of extreme high bone mass: contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genesGregson, Celia L., Newell, Felicity, Leo, Paul J., Clark, Graeme R., Paternoster, Lavinia, Marshall, Mhairi, Forgetta, Vincenzo, Morris, John A., Ge, Bing, Bao, Xiao, Duncan Bassett, J. H., Williams, Graham R., Youlten, Scott E., Croucher, Peter I., Davey Smith, George, Evans, David M., Kemp, John P., Brown, Matthew A., Tobias, Jon H. and Duncan, Emma L. (2018). Genome-wide association study of extreme high bone mass: contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. Bone, 114, 62-71. doi: 10.1016/j.bone.2018.06.001 |
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2018 Journal Article Assessing the role of DNA methylation-derived neutrophil-to-lymphocyte ratio in rheumatoid arthritisAmbatipudi, Srikant, Sharp, Gemma C., Clarke, Sarah L. N., Plant, Darren, Tobias, Jonathan H., Evans, David M., Barton, Anne and Belton, Caroline L. (2018). Assessing the role of DNA methylation-derived neutrophil-to-lymphocyte ratio in rheumatoid arthritis. Journal of Immunology Research, 2018 2624981, 1-10. doi: 10.1155/2018/2624981 |
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2018 Journal Article Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization studyMoen, Gunn-Helen, Qvigstad, Elisabeth, Birkeland, Kåre I., Evans, David M. and Sommer, Christine (2018). Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study. The American Journal of Clinical Nutrition, 108 (2), 398-404. doi: 10.1093/ajcn/nqy101 |
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2018 Journal Article Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humansCuellar Partida, Gabriel, Laurin, Charles, Ring, Susan M., Gaunt, Tom R., McRae, Allan, Visscher, Peter M., Montgomery, Grant W., Martin, Nicholas G., Hemani, Gibran, Suderman, Matthew, Relton, Caroline L., Davey Smith, George and Evans, David M. (2018). Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans. Human Molecular Genetics, 27 (16), 2927-2939. doi: 10.1093/hmg/ddy206 |
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2018 Journal Article Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive errorTedja, Milly S., Wojciechowski, Robert, Hysi, Pirro G., Eriksson, Nicholas, Furlotte, Nicholas A., Verhoeven, Virginie J. M., Iglesias, Adriana I., Meester-Smoor, Magda A., Tompson, Stuart W., Fan, Qiao, Khawaja, Anthony P., Cheng, Ching-Yu, Höhn, René, Yamashiro, Kenji, Wenocur, Adam, Grazal, Clare, Haller, Toomas, Metspalu, Andres, Wedenoja, Juho, Jonas, Jost B., Wang, Ya Xing, Xie, Jing, Mitchell, Paul, Foster, Paul J., Klein, Barbara E. K., Klein, Ronald, Paterson, Andrew D., Hosseini, S. Mohsen, Shah, Rupal L. ... UK Biobank Eye and Vision Consortium (2018). Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nature Genetics, 50 (6), 834-848. doi: 10.1038/s41588-018-0127-7 |
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2018 Journal Article The MR-Base platform supports systematic causal inference across the human phenomeHemani, Gibran, Zheng, Jie, Elsworth, Benjamin, Wade, Kaitlin H., Haberland, Valeriia, Baird, Denis, Laurin, Charles, Burgess, Stephen, Bowden, Jack, Langdon, Ryan, Tan, Vanessa Y., Yarmolinsky, James, Shihab, Hashem A., Timpson, Nicholas J., Evans, David M., Relton, Caroline, Martin, Richard M., Davey Smith, George, Gaunt, Tom R. and Haycock, Philip C. (2018). The MR-Base platform supports systematic causal inference across the human phenome. eLife, 7 e34408. doi: 10.7554/eLife.34408 |
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2018 Journal Article Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization AnalysisYarmolinsky, James, Bonilla, Carolina, Haycock, Philip C., Langdon, Ryan J. Q., Lotta, Luca A., Langenberg, Claudia, Relton, Caroline L., Lewis, Sarah J., Evans, David M., PRACTICAL Consortium, Davey Smith, George and Martin, Richard M. (2018). Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis. Journal of the National Cancer Institute, 110 (9) djy081, 1035-1038. doi: 10.1093/jnci/djy081 |
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2018 Journal Article Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritabilityHysi, Pirro G., Valdes, Ana M., Liu, Fan, Furlotte, Nicholas A., Evans, David M., Bataille, Veronique, Visconti, Alessia, Hemani, Gibran, McMahon, George, Ring, Susan M., Smith, George Davey, Duffy, David L., Zhu, Gu, Gordon, Scott D., Medland, Sarah E., Lin, Bochao D., Willemsen, Gonneke, Jan Hottenga, Jouke, Vuckovic, Dragana, Girotto, Giorgia, Gandin, Ilaria, Sala, Cinzia, Concas, Maria Pina, Brumat, Marco, Gasparini, Paolo, Toniolo, Daniela, Cocca, Massimiliano, Robino, Antonietta, Yazar, Seyhan ... Spector, Timothy D. (2018). Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability. Nature Genetics, 50 (5), 652-656. doi: 10.1038/s41588-018-0100-5 |
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2018 Journal Article Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in uteroWarrington, Nicole M., Shevroja, Enisa, Hemani, Gibran, Hysi, Pirro G., Jiang, Yunxuan, Auton, Adam, Boer, Cindy G., Mangino, Massimo, Wang, Carol A., Kemp, John P., McMahon, George, Medina-Gomez, Carolina, Hickey, Martha, Trajanoska, Katerina, Wolke, Dieter, Ikram, Arfan M., 23 and Me Research Team, Montgomery, Grant W., Felix, Janine F., Wright, Margaret J., Mackey, David A., Jaddoe, Vincent W., Martin, Nicholas G., Tung, Joyce Y., Davey Smith, George, Pennell, Craig E., Spector, Tim D., van Meurs, Joyce, Rivadeneira, Fernando ... Evans, David M. (2018). Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero. Human Molecular Genetics, 27 (11), 2025-2038. doi: 10.1093/hmg/ddy121 |
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2018 Journal Article Elucidating the genetics of craniofacial shapeEvans, David M (2018). Elucidating the genetics of craniofacial shape. Nature Genetics, 50 (3), 319-321. doi: 10.1038/s41588-018-0065-4 |
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2018 Journal Article Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inferenceCorbin, Laura J., Tan, Vanessa Y., Hughes, David A., Wade, Kaitlin H., Paul, Dirk S., Tansey, Katherine E., Butcher, Frances, Dudbridge, Frank, Howson, Joanna M., Jallow, Momodou W., John, Catherine, Kingston, Nathalie, Lindgren, Cecilia M., O'Donavan, Michael, O'Rahilly, Stephen, Owen, Michael J., Palmer, Colin N. A., Pearson, Ewan R., Scott, Robert A., van Heel, David A., Whittaker, John, Frayling, Tim, Tobin, Martin D., Wain, Louise V., Smith, George Davey, Evans, David M., Karpe, Fredrik, McCarthy, Mark I., Danesh, John ... Timpson, Nicholas J. (2018). Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference. Nature Communications, 9 (1) 711, 711. doi: 10.1038/s41467-018-03109-y |
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2018 Journal Article Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal geneticsBeaumont, Robin N., Warrington, Nicole M., Cavadino, Alana, Tyrrell, Jessica, Nodzenski, Michael, Horikoshi, Momoko, Geller, Frank, Myhre, Ronny, Richmond, Rebecca C., Paternoster, Lavinia, Bradfield, Jonathan P., Kreiner-Møller, Eskil, Huikari, Ville, Metrustry, Sarah, Lunetta, Kathryn L., Painter, Jodie N., Hottenga, Jouke-Jan, Allard, Catherine, Barton, Sheila J., Espinosa, Ana, Marsh, Julie A., Potter, Catherine, Zhang, Ge, Ang, Wei, Berry, Diane J., Bouchard, Luigi, Das, Shikta, Early Growth Genetics (EGG) Consortium, Hakonarson, Hakon ... Freathy, Rachel M. (2018). Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Human Molecular Genetics, 27 (4) ddx429, 742-756. doi: 10.1093/hmg/ddx429 |
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2018 Journal Article Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK BiobankWarrington, Nicole M., Freathy, Rachel M., Neale, Michael C. and Evans, David M. (2018). Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank. International Journal of Epidemiology, 47 (4), 1229-1241. doi: 10.1093/ije/dyy015 |
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2018 Journal Article MHC-dependent mate selection within 872 spousal pairs of European ancestry from the health and retirement studyQiao, Zhen, Powell, Joseph E. and Evans, David M. (2018). MHC-dependent mate selection within 872 spousal pairs of European ancestry from the health and retirement study. Genes, 9 (1) 53, 53. doi: 10.3390/genes9010053 |
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2018 Journal Article Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific EffectsMedina-Gomez, Carolina, Kemp, John P., Trajanoska, Katerina, Luan, Jian'an, Chesi, Alessandra, Ahluwalia, Tarunveer S., Mook-Kanamori, Dennis O., Ham, Annelies, Hartwig, Fernando P., Evans, Daniel S., Joro, Raimo, Nedeljkovic, Ivana, Zheng, Hou-Feng, Zhu, Kun, Atalay, Mustafa, Liu, Ching-Ti, Nethander, Maria, Broer, Linda, Porleifsson, Gudmar, Mullin, Benjamin H., Handelman, Samuel K., Nalls, Mike A., Jessen, Leon E, Heppe, Denise H. M., Richards, J. Brent, Wang, Carol, Chawes, Bo, Schraut, Katharina E, Amin, Najaf ... Rivadeneira, Fernando (2018). Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. American journal of human genetics, 102 (1), 88-102. doi: 10.1016/j.ajhg.2017.12.005 |
